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List of works by Thomas R Cox

AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.

scientific article

Automated annotation and visualisation of high-resolution spatial proteomic mass spectrometry imaging data using HIT-MAP

scientific article published on 28 May 2021

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

scientific article published on 12 August 2019

Charting the unexplored extracellular matrix in cancer.

scientific article published on 19 April 2018

Correlation of Ultrasound Shear Wave Elastography with Pathological Analysis in a Xenografic Tumour Model

scientific article

Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism

scientific article published on 23 October 2015

Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments

scientific article published in September 2017

Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease.

scientific article published on 2 November 2017

Fibrosis and Cancer: Partners in Crime or Opposing Forces?

scientific article

Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis

scientific article

Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

scientific article

ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix.

scientific article published on 12 June 2017

Kinome-wide decoding of network-attacking mutations rewiring cancer signaling

scientific article

LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis

scientific article published on 23 January 2013

LOXL1 Is Regulated by Integrin α11 and Promotes Non-Small Cell Lung Cancer Tumorigenicity

scientific article published on 22 May 2019

LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling

scientific article published on January 2013

LOXL2-mediated matrix remodeling in metastasis and mammary gland involution

scientific article published on 13 January 2011

Lamin A/C is a risk biomarker in colorectal cancer

scientific article

Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis

scientific article

Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.

scientific article

Lysyl oxidase in colorectal cancer

scientific article published on 05 September 2013

Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis

scientific article

Meeting report: Metastasis Research Society (MRS) 17th Biennial conference and associated Young Investigator Satellite Meeting (YISM) on cancer metastasis

scientific article published on 23 January 2019

Meeting report: Metastasis Research Society-Chinese Tumor Metastasis Society joint conference on metastasis

scientific article published on 4 March 2017

Molecular Pathways: Connecting Fibrosis and Solid Tumor Metastasis

scientific article published on 01 July 2014

Multi-Channel Optical Coherence Elastography Using Relative and Absolute Shear-Wave Time of Flight

scientific article

Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients

scientific article published on 26 May 2016

Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer

scientific article

Pre-metastatic niches: organ-specific homes for metastases.

scientific article published on 17 March 2017

Recent advances in understanding the complexities of metastasis

scientific article published on 01 August 2018

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

scientific article

Removing physiological motion from intravital and clinical functional imaging data

scientific article published on 09 July 2018

Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse.

scientific article published on 18 February 2018

Stromal cell diversity associated with immune evasion in human triple-negative breast cancer

scientific article published on 13 August 2020

Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer

scientific article published on 28 October 2017

Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer

scientific article published in Nature Communications

Targeting the lysyl oxidases in tumour desmoplasia

scientific article published on 01 December 2019

The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development

scientific article published on 01 August 2019

The extracellular matrix as a key regulator of intracellular signalling networks.

scientific article published on 6 March 2018

The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.

scientific article published on 27 May 2015

The interplay between extracellular matrix remodelling and kinase signalling in cancer progression and metastasis.

scientific article published on 23 November 2017

The pre-metastatic niche: is metastasis random?

scientific article

The rationale for targeting the LOX family in cancer

scientific article published on 19 July 2012

The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer

scientific article

The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis

scientific article

Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology.

scientific article published on 4 December 2017

Tissue section AFM: In situ ultrastructural imaging of native biomolecules

scientific article

Transient targeting of the pancreatic cancer stroma as a 'fine-tuned' anti-tumor and anti-metastatic therapy.

scientific article published on 3 October 2017

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

scientific article published in April 2017

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