List of works - Enni Markkanen

A switch between DNA polymerases δ and λ promotes error-free bypass of 8-oxo-G lesions

scientific article

Analysis of Gene Expression Signatures in Cancer-Associated Stroma from Canine Mammary Tumours Reveals Molecular Homology to Human Breast Carcinomas

scientific article

Base excision repair in physiology and pathology of the central nervous system

scientific article published on 30 November 2012

Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability

scientific article

DNA Damage and Repair in Schizophrenia and Autism: Implications for Cancer Comorbidity and Beyond

scientific article

DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass

scientific article

Deficient DNA base-excision repair in the forebrain leads to a sex-specific anxiety-like phenotype in mice

scientific article published in 2022

Differential stromal reprogramming in benign and malignant naturally occurring canine mammary tumours identifies disease-modulating stromal components

scientific article published on 26 March 2020

Gap-directed translesion DNA synthesis of an abasic site on circular DNA templates by a human replication complex.

scientific article

Identification of disease-promoting stromal components by comparative proteomic and transcriptomic profiling of canine mammary tumors using laser-capture microdissected FFPE tissue

scientific article published on 29 March 2021

Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability

scientific article published on 8 November 2017

In Vitro Gap-directed Translesion DNA Synthesis of an Abasic Site Involving Human DNA Polymerases ϵ, λ, and β ⬇️

scientific article published on July 13, 2011

Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation

scientific article

MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNA

scientific article published in 2013

Next-generation RNA sequencing of FFPE subsections reveals highly conserved stromal reprogramming between canine and human mammary carcinoma

scientific article published on 08 August 2019

Not breathing is not an option: How to deal with oxidative DNA damage

scientific article published on 22 September 2017

Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine

scientific article published on June 2010

Persistent DNA damage triggers activation of the integrated stress response to promote cell survival under nutrient restriction

scientific article published on 30 March 2020

Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination

scientific article published on 27 December 2011

Regulation of oxidative DNA damage repair: The adenine:8-oxo-guanine problem

scientific article published on 15 March 2012

Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.

scientific article published on 29 December 2015

The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery

scientific article

Ubiquitylation of DNA polymerase λ.

scientific article published on 08 April 2011

List of works by Enni Markkanen

A switch between DNA polymerases δ and λ promotes error-free bypass of 8-oxo-G lesions

Analysis of Gene Expression Signatures in Cancer-Associated Stroma from Canine Mammary Tumours Reveals Molecular Homology to Human Breast Carcinomas

Base excision repair in physiology and pathology of the central nervous system

Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability

DNA Damage and Repair in Schizophrenia and Autism: Implications for Cancer Comorbidity and Beyond

DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass

Deficient DNA base-excision repair in the forebrain leads to a sex-specific anxiety-like phenotype in mice

Differential stromal reprogramming in benign and malignant naturally occurring canine mammary tumours identifies disease-modulating stromal components

Gap-directed translesion DNA synthesis of an abasic site on circular DNA templates by a human replication complex.

Identification of disease-promoting stromal components by comparative proteomic and transcriptomic profiling of canine mammary tumors using laser-capture microdissected FFPE tissue

Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability

In Vitro Gap-directed Translesion DNA Synthesis of an Abasic Site Involving Human DNA Polymerases ϵ, λ, and β ⬇️

Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation

MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNA

Next-generation RNA sequencing of FFPE subsections reveals highly conserved stromal reprogramming between canine and human mammary carcinoma

Not breathing is not an option: How to deal with oxidative DNA damage

Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine

Persistent DNA damage triggers activation of the integrated stress response to promote cell survival under nutrient restriction

Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination

Regulation of oxidative DNA damage repair: The adenine:8-oxo-guanine problem

Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.

The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery

Ubiquitylation of DNA polymerase λ.