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List of works by Jaap Jan Boelens

A novel Dutch mutation in UNC13D reveals an essential role of the C2B domain in munc13-4 function

scientific article (publication date: April 2012)

A novel FcγRIIa Q27W gene variant is associated with common variable immune deficiency through defective FcγRIIa downstream signaling.

scientific article published on 19 September 2014

A risk factor analysis of outcomes after unrelated cord blood transplantation for children with Wiskott-Aldrich syndrome

scientific article

A semi-mechanistic model based on glutathione depletion to describe intra-individual reduction in busulfan clearance

scientific article published on 18 February 2020

Adenovirus DNA positivity in nasopharyngeal aspirate preceding hematopoietic stem cell transplantation: a very strong risk factor for adenovirus DNAemia in pediatric patients

scientific article published on 01 November 2009

Advances in unrelated and alternative donor hematopoietic cell transplantation for nonmalignant disorders

scientific article

Allele-level HLA matching for umbilical cord blood transplantation for non-malignant diseases in children: a retrospective analysis.

scientific article published on 13 June 2017

Allogeneic haematopoietic stem cell transplantation for mitochondrial neurogastrointestinal encephalomyopathy

scientific article published on 10 August 2015

Allogeneic hematopoietic SCT for alpha-mannosidosis: an analysis of 17 patients

scientific article published on 9 May 2011

Anakinra for flares of pyogenic arthritis in PAPA syndrome

scientific article published on 05 January 2005

Antigen cross-presentation: extending recent laboratory findings to therapeutic intervention.

scientific article published on 11 May 2011

Antithymocyte Globulin: Steps Toward Individualized Dosing

scientific article published on 28 November 2017

Antithymocyte globulin: Importance of good clinical pharmacological practice.

scientific article

Antitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentation

scientific article

Association between anti-thymocyte globulin exposure and CD4+ immune reconstitution in paediatric haemopoietic cell transplantation: a multicentre, retrospective pharmacodynamic cohort analysis

scientific article published on 21 April 2015

Association between anti-thymocyte globulin exposure and survival outcomes in adult unrelated haemopoietic cell transplantation: a multicentre, retrospective, pharmacodynamic cohort analysis

scientific article

Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematologic stem cell transplantation

scientific article published in February 2009

Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis.

scientific article published on 13 October 2016

Biomarker profiling of steroid-resistant acute GVHD in patients after infusion of mesenchymal stromal cells.

scientific article published on 3 April 2015

Biomaterial-associated persistence of Staphylococcus epidermidis in pericatheter macrophages

scientific article published on 13 April 2000

Body weight-dependent pharmacokinetics of busulfan in paediatric haematopoietic stem cell transplantation patients: towards individualized dosing

scientific article published in May 2012

Bone-marrow transplantation in non-malignant disease

scientific article published on 02 September 2009

Breastfeeding, atopy, and asthma

scientific article published in January 2003

Busulfan after HSCT in children and young adults - Authors' reply

scientific article

Challenges and opportunities for international cooperative studies in pediatric hematopoeitic cell transplantation: priorities of the Westhafen Intercontinental Group

scientific article

Challenges in the harmonization of immune monitoring studies and trial design for cell-based therapies in the context of hematopoietic cell transplantation for pediatric cancer patients.

scientific article published on December 2015

Changing winds in refractory autoimmune disease in children: clearing the road for tolerance with cellular therapies

scientific article published on May 2012

Choice of conditioning regimens for bone marrow transplantation in severe aplastic anemia

scientific article published on 01 October 2019

Chromosomally integrated human herpesvirus 6: transmission via cord blood-derived unrelated hematopoietic stem cell transplantation.

scientific article published on 8 July 2009

Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation

scientific article published on 19 January 2020

Clofarabine-fludarabine-busulfan in HCT for pediatric leukemia: an effective, low toxicity, TBI-free conditioning regimen

scientific article published on 01 March 2022

Cognate CD4 T-cell licensing of dendritic cells heralds anti-cytomegalovirus CD8 T-cell immunity after human allogeneic umbilical cord blood transplantation

scientific article

Comparison of pediatric allogeneic transplant outcomes using myeloablative busulfan with cyclophosphamide or fludarabine

scientific article published on 01 June 2018

Cord-Blood-Stem-Cell-Derived Conventional Dendritic Cells Specifically Originate from CD115-Expressing Precursors

scientific article published on 05 February 2019

Current international perspectives on hematopoietic stem cell transplantation for inherited metabolic disorders.

scientific article published on February 2010

Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients

scientific article published on 15 September 2007

Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations

scientific article published on 17 May 2013

Defibrotide for prophylaxis of hepatic veno-occlusive disease in paediatric haemopoietic stem-cell transplantation: an open-label, phase 3, randomised controlled trial

scientific article published on 23 February 2012

Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease: Final Results From the International Compassionate-Use Program

scientific article published on 7 July 2016

Dendritic Cell Therapy in an Allogeneic-Hematopoietic Cell Transplantation Setting: An Effective Strategy toward Better Disease Control?

scientific article

Development of a unique anti-AML immune therapy consisting of cord blood HSCT and cord blood stem cell-derived dendritic cell (CB-DC) vaccination.

scientific article published on 7 November 2013

Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity

scientific article

Diffusion tensor imaging in metachromatic leukodystrophy.

scientific article published on 30 January 2018

Does high-resolution CT has diagnostic value in patients presenting with respiratory symptoms after hematopoietic stem cell transplantation?

scientific article published on 02 February 2011

Dried blood spot analysis: an easy and reliable tool to monitor the biochemical effect of hematopoietic stem cell transplantation in hurler syndrome patients.

scientific article published on 21 January 2010

EBV post transplantation lymphoproliferative disease-associated pneumomediastinum in a pediatric patient with long-lasting low loads of plasma EBV-DNA positivity

scientific article published on 28 July 2008

Early Umbilical Cord Blood-Derived Stem Cell Transplantation Does Not Prevent Neurological Deterioration in Mucopolysaccharidosis Type III.

scientific article

Early and late outcomes after cord blood transplantation for pediatric patients with inherited leukodystrophies

scientific article published on 04 January 2018

Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe aplastic anemia

scientific article published on 24 March 2017

Effect of weight and maturation on busulfan clearance in infants and small children undergoing hematopoietic cell transplantation

scientific article published on 09 September 2013

Efficacy of hematopoietic cell transplantation in metachromatic leukodystrophy: the Dutch experience

scientific article published on 26 April 2016

Enhanced susceptibility to subcutaneous abscess formation and persistent infection around catheters is associated with sustained interleukin-1beta levels

scientific article

Enzyme replacement therapy and/or hematopoietic stem cell transplantation at diagnosis in patients with mucopolysaccharidosis type I: results of a European consensus procedure

scientific article

Epstein-Barr virus-associated haemophagocytic lympho-histiocytosis after stem cell transplantation.

scientific article published on 2 October 2006

Evaluation of effects of busulfan and DMA on SOS in pediatric stem cell recipients.

scientific article published on 30 October 2013

Excellent T-cell reconstitution and survival depend on low ATG exposure after pediatric cord blood transplantation.

scientific article

Familial hemophagocytic lymphohistiocytosis in a pediatric patient diagnosed by brain magnetic resonance imaging

scientific article

Fatal hemophagocytic lymphohistiocytosis in X-linked chronic granulomatous disease associated with a perforin gene variant

scientific article

Fcγ receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells

scientific article published on 23 October 2012

Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation

scientific article published on 01 March 2018

Fine-Tuning Antithymocyte Globulin Dosing and Harmonizing Clinical Trial Design.

scientific article published on 7 February 2018

First analysis of human herpesvirus 6T-cell responses: specific boosting after HHV6 reactivation in stem cell transplantation recipients.

scientific article

Fludarabine and exposure-targeted busulfan compares favorably with busulfan/cyclophosphamide-based regimens in pediatric hematopoietic cell transplantation: maintaining efficacy with less toxicity.

scientific article published on 04 December 2013

Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes

scientific article published on 01 July 2019

Fludarabine in paediatric steroid-refractory inflammatory lung injury after stem cell transplantation

scientific article published on 01 February 2013

Functional and genetic characterization of two extremely rare cases of Williams-Beuren syndrome associated with chronic granulomatous disease.

scientific article published on 23 January 2013

GSTA1 diplotypes affect busulfan clearance and toxicity in children undergoing allogeneic hematopoietic stem cell transplantation: a multicenter study.

scientific article published on 27 August 2017

Gallbladder and the risk of polyps and carcinoma in metachromatic leukodystrophy

scientific article published on 3 June 2016

Generation of a cord blood-derived Wilms Tumor 1 dendritic cell vaccine for AML patients treated with allogeneic cord blood transplantation.

scientific article

Glutathione S-transferase polymorphisms are not associated with population pharmacokinetic parameters of busulfan in pediatric patients.

scientific article published in August 2008

Granulocyte concentrates: prolonged functional capacity during storage in the presence of phenotypic changes

scientific article published on 27 May 2008

Haematopoietic cell transplantation (HCT) in combination with enzyme replacement therapy (ERT) in patients with Hurler syndrome.

scientific article published on 22 May 2006

Hematopoietic cell transplantation does not prevent myelopathy in X-linked adrenoleukodystrophy: a retrospective study

scientific article published on 9 December 2014

Hematopoietic cell transplantation for mucopolysaccharidosis patients is safe and effective: results after implementation of international guidelines

scientific article published on 20 February 2015

Hematopoietic stem cell transplantation for CD40 ligand deficiency: results from an EBMT/ESID-IEWP-SCETIDE-PIDTC Study

scientific article published on 17 January 2019

Hematopoietic stem cell transplantation for infantile osteopetrosis

scientific article

Hemorrhagic cystitis in a cohort of pediatric transplantations: incidence, treatment, outcome, and risk factors.

scientific article published on 24 May 2013

High Diagnostic Yield of Dedicated Pulmonary Screening before Hematopoietic Cell Transplantation in Children.

scientific article published on 10 June 2015

High-resolution CT can differentiate between alloimmune and nonalloimmune lung disease early after hematopoietic cell transplantation

scientific article published in September 2014

Highly variable plasma concentrations of voriconazole in pediatric hematopoietic stem cell transplantation patients.

scientific article published on 31 October 2012

How I treat adenovirus in hematopoietic stem cell transplant recipients

scientific article published on 13 September 2010

How to define and measure thymopoiesis after transplantation?

scientific article published on 03 May 2018

Human herpes virus 6 plasma DNA positivity after hematopoietic stem cell transplantation in children: an important risk factor for clinical outcome.

scientific article published in July 2008

Human herpesvirus 6 viremia affects T-cell reconstitution after allogeneic hematopoietic stem cell transplantation

scientific article published on 01 February 2018

Human herpesvirus type 6 reactivation after haematopoietic stem cell transplantation.

scientific article published on October 2008

Immune Reconstitution after Allogeneic Hematopoietic Cell Transplantation in Children

scientific article published on September 2015

Immune reconstitution and outcomes after conditioning with anti-thymocyte-globulin in unrelated cord blood transplantation; the good, the bad, and the ugly.

scientific article published on 16 May 2017

Immune reconstitution kinetics as an early predictor for mortality using various hematopoietic stem cell sources in children.

scientific article

Impact of thymoglobulin prior to pediatric unrelated umbilical cord blood transplantation on immune reconstitution and clinical outcome

scientific article published on November 2013

Improvement of White Matter Changes on Neuroimaging Modalities After Stem Cell Transplant in Metachromatic Leukodystrophy

scientific article published on 01 June 2013

In vivo and in vitro palatability testing of a new paediatric formulation of valaciclovir

scientific article published on 11 August 2017

Incomplete biomarker response in mucopolysaccharidosis type I after successful hematopoietic cell transplantation

scientific article published on 18 May 2017

Increased proportion of perforin-expressing CD8+T-cells indicates control of herpesvirus reactivation in children after stem cell transplantation.

scientific article published on 22 March 2013

Individualized conditioning regimes in cord blood transplantation: Towards improved and predictable safety and efficacy.

scientific article

Innate immune recovery predicts CD4+ T-cell reconstitution after Hematopoietic Cell Transplantation

article

Intensive care unit mortality trends in children after hematopoietic stem cell transplantation: a meta-regression analysis

scientific article published on October 2008

Interferon-gamma protects against biomaterial-associated Staphylococcus epidermidis infection in mice

scientific article published on 01 March 2000

Interleukin-1 receptor type I gene-deficient mice are less susceptible to Staphylococcus epidermidis biomaterial-associated infection than are wild-type mice.

scientific article published on December 2000

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy

scientific article

Leukemia-free survival in myeloid leukemia, but not in lymphoid leukemia, is predicted by early CD4+ reconstitution following unrelated cord blood transplantation in children: a multicenter retrospective cohort analysis.

scientific article published on 9 May 2016

Life-threatening human herpes virus-6 infection in early childhood: presenting symptom of a primary immunodeficiency?

scientific article published in March 2009

Long-term effect of hematopoietic cell transplantation on systemic inflammation in patients with mucopolysaccharidoses

scientific article published on 01 August 2021

Long-term outcome of Hurler syndrome patients after hematopoietic cell transplantation: an international multicenter study.

scientific article published on 26 January 2015

Lymphoid and myeloid immune cell reconstitution after nicotinamide-expanded cord blood transplantation

scientific article published on 26 July 2021

Metachromatic leukodystrophy genotypes in The Netherlands reveal novel pathogenic ARSA variants in non-Caucasian patients

scientific article published on 07 July 2020

Metachromatic leukodystrophy: Disease spectrum and approaches for treatment

scientific article published on 16 October 2014

Morbidity and Mortality Associated With Respiratory Virus Infections in Allogeneic Hematopoietic Cell Transplant: Too Little Defense or Harmful Immunity?

scientific article published in 2018

Multi-institutional assessments of transplantation for metabolic disorders

scientific article

Musculoskeletal manifestations of lysosomal storage disorders.

scientific article

Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma

scientific article

Neurodevelopmental Outcome after Hematopoietic Cell Transplantation in Inborn Errors of Metabolism: Current Considerations and Future Perspectives.

scientific article published on 16 June 2016

Ocular complications in children within 1 year after hematopoietic stem cell transplantation

scientific article published in April 2013

Once-daily intravenous busulfan with therapeutic drug monitoring compared to conventional oral busulfan improves survival and engraftment in children undergoing allogeneic stem cell transplantation

scientific article published in January 2008

Outcome of hematopoietic stem cell transplantation for adenosine deaminase-deficient severe combined immunodeficiency.

scientific article published on 12 July 2012

Outcomes of hematopoietic stem cell transplantation for Hurler's syndrome in Europe: a risk factor analysis for graft failure

scientific article published on 28 May 2007

Outcomes of transplantation of unrelated cord blood in children with malignant and non-malignant diseases: an Utrecht-Prague collaborative study

scientific article published on 10 November 2008

Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning

scientific article

Paediatric reduced intensity conditioning: analysis of centre strategies on regimens and definitions by the EBMT Paediatric Diseases and Complications and Quality of Life WP.

scientific article published on 26 January 2015

Pain: a prevalent feature in patients with mucopolysaccharidosis. Results of a cross-sectional national survey

scientific article published on 22 July 2014

Perioperative complications in patients diagnosed with mucopolysaccharidosis and the impact of enzyme replacement therapy followed by hematopoietic stem cell transplantation at early age.

scientific article published on 10 March 2014

Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood Unit Expanded Ex Vivo With Nicotinamide.

scientific article published on 4 December 2018

Pleconaril-resistant chronic parechovirus-associated enteropathy in agammaglobulinaemia

scientific article published on 01 January 2011

Population Pharmacokinetics of Alemtuzumab (Campath) in Pediatric Hematopoietic Cell Transplantation: Towards Individualized Dosing to Improve Outcome

scientific article published on 01 December 2019

Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

scientific article published on 01 May 2019

Population pharmacokinetic modeling of Thymoglobulin(®) in children receiving allogeneic-hematopoietic cell transplantation: towards improved survival through individualized dosing

scientific article published in April 2015

Population pharmacokinetics of dimethylacetamide in children during standard and once-daily IV busulfan administration.

scientific article published on 15 September 2013

Potential of Systemic Allogeneic Mesenchymal Stromal Cell Therapy for Children with Recessive Dystrophic Epidermolysis Bullosa

scientific article published on 23 April 2015

Pre-emptive granulocyte transfusions enable allogeneic hematopoietic stem cell transplantation in pediatric patients with chronic infections

scientific article published on 01 February 2006

Predicted Indirectly ReCognizable HLA Epitopes Class I Promote Antileukemia Responses after Cord Blood Transplantation: Indications for a Potential Novel Donor Selection Tool.

scientific article published on 26 August 2015

Predictive performance of a busulfan pharmacokinetic model in children and young adults.

scientific article published in October 2012

Predictors of invasive fungal infection in pediatric allogeneic hematopoietic SCT recipients

scientific article published on 14 October 2013

Quality of life of Hurler syndrome patients after successful hematopoietic stem cell transplantation

scientific article published on 07 November 2017

Quantitative MR spectroscopic imaging in metachromatic leukodystrophy: value for prognosis and treatment

scientific article published on 9 September 2017

Rabbit ATG/ATLG in preventing graft-versus-host disease after allogeneic stem cell transplantation: consensus-based recommendations by an international expert panel

scientific article published on 22 January 2020

Rabbit anti-T cell globulin in allogeneic hematopoietic cell transplantation

scientific article

Rabbit anti-human-T-lymphocyte globulin-less is more.

scientific article

Recurrent and opportunistic infections in children with primary intestinal lymphangiectasia

scientific article published on 01 March 2007

Related and unrelated donor transplantation for β-thalassemia major: results of an international survey

scientific article published on 01 September 2019

Relationship between Mixed Donor-Recipient Chimerism and Disease Recurrence after Hematopoietic Cell Transplantation for Sickle Cell Disease

scientific article published on 4 September 2017

Respiratory Virus prior to Hematopoietic Cell Transplantation is associated with allo-immune mediated lung syndromes.

scientific article

Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome

scientific article

Simultaneous quantification of busulfan, clofarabine and F-ARA-A using isotope labelled standards and standard addition in plasma by LC-MS/MS for exposure monitoring in hematopoietic cell transplantation conditioning

scientific article published on 15 April 2017

Slowly Progressive Psychiatric Symptoms: Think Metachromatic Leukodystrophy

scientific article published in February 2018

Spectrum of clinical presentations in familial hemophagocytic lymphohistiocytosis type 5 patients with mutations in STXBP2.

scientific article published on 17 June 2010

Stem cell comparison: what can we learn clinically from unrelated cord blood transplantation as an alternative stem cell source?

scientific article published on 18 March 2015

Strategies before, during, and after hematopoietic cell transplantation to improve T-cell immune reconstitution.

scientific article published on 3 October 2016

Strategies to Genetically Modulate Dendritic Cells to Potentiate Anti-Tumor Responses in Hematologic Malignancies.

scientific article published on 18 May 2018

Strong Association between Respiratory Viral Infection Early after Hematopoietic Stem Cell Transplantation and the Development of Life-Threatening Acute and Chronic Alloimmune Lung Syndromes

article

Subcutaneous abscess formation around catheters induced by viable and nonviable Staphylococcus epidermidis as well as by small amounts of bacterial cell wall components

scientific article published on 01 June 2000

Successful cord blood transplantation in a premature and dysmature neonate of 1700 g with reticular dysgenesis

scientific article published on 29 January 2007

Sufficient Immunosuppression with Thymoglobulin Is Essential for a Successful Haplo-Myeloid Bridge in Haploidentical-Cord Blood Transplantation.

scientific article published on 25 June 2015

Survival in a recent cohort of mechanically ventilated pediatric allogeneic hematopoietic stem cell transplantation recipients

scientific article published on 01 December 2008

The clinical outcome of Hurler syndrome after stem cell transplantation.

scientific article published on May 2008

The influence of stem cell source on transplant outcomes for pediatric patients with acute myeloid leukemia

scientific article published on 01 April 2019

The power of cord blood cells

scientific article

Towards evidence-based dosing regimens in children on the basis of population pharmacokinetic pharmacodynamic modelling

scientific article

Towards new long-term composite 'Quality of Survival' endpoints

scientific article published on 12 June 2020

Transplantation in inborn errors of metabolism: current considerations and future perspectives

scientific article published on 30 July 2014

Trends in haematopoietic cell transplantation for inborn errors of metabolism

scientific article published on April 2006

Umbilical cord blood from an unrelated donor as source for stem cell transplantations in inborn errors of metabolism

scientific article published in August 2008

Umbilical cord blood: advances and opportunities. Introduction

scientific article published on 01 June 2015

Use of cord blood derived T-cells in cancer immunotherapy: milestones achieved and future perspectives.

scientific article

Viral PCR positivity in stool before allogeneic hematopoietic cell transplantation is strongly associated with acute intestinal graft-versus-host disease

scientific article published on 15 January 2015

Viral reactivations and associated outcomes in the context of immune reconstitution after pediatric hematopoietic cell transplantation

scientific article published on 6 April 2017

Will post-transplantation cell therapies for pediatric patients become standard of care?

scientific article

X-ALD: centralize care in an international network ⬇️

scientific article published on August 18, 2011

[Clinical reasoning and decision-making in practice. A patient with fever and pancytopenia]

scientific article published on 01 August 2008

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