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List of works by Brigitte van Zundert

1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA

scientific article

A Myosin Va mutant mouse with disruptions in glutamate synaptic development and mature plasticity in visual cortex

scientific article published on May 2013

ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers

scientific article

ALS-linked protein disulfide isomerase variants cause motor dysfunction

scientific article

ALS: new molecular mechanisms and emerging therapeutic targets.

scientific article

Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress

scientific article published on 07 February 2014

Changes on the properties of glycine receptors during neuronal development

scientific article published on 01 December 2004

Chronic infusion of SOD1G93A astrocyte-secreted factors induces spinal motoneuron degeneration and neuromuscular dysfunction in healthy rats.

scientific article

Developmental-dependent action of microtubule depolymerization on the function and structure of synaptic glycine receptor clusters in spinal neurons

scientific article published on 10 September 2003

Differential roles of NMDA Receptor Subtypes NR2A and NR2B in dendritic branch development and requirement of RasGRF1.

scientific article published on 27 January 2010

Dissecting the role of redox signaling in neuronal development

scientific article published on 14 February 2016

Downregulation of the Polycomb-Associated Methyltransferase Ezh2 during Maturation of Hippocampal Neurons Is Mediated by MicroRNAs Let-7 and miR-124

scientific article published on 11 November 2020

Early pathogenesis in the adult-onset neurodegenerative disease amyotrophic lateral sclerosis

scientific article published on November 2012

Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B.

scientific article published on 9 October 2015

Epigenetic Signatures at the RUNX2-P1 and Sp7 Gene Promoters Control Osteogenic Lineage Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells

scientific article published on 30 September 2016

Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer's disease mice

scientific article published on 16 November 2017

Epigenetic silencing of the osteoblast-lineage gene program during hippocampal maturation

scientific article published on 02 November 2020

Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons

scientific journal article

Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis

scientific article published on 29 December 2017

Glycine receptors involved in synaptic transmission are selectively regulated by the cytoskeleton in mouse spinal neurons

scientific article published in January 2002

Glycinergic and GABAergic synaptic transmission are differentially affected by gephyrin in spinal neurons

scientific article published in July 2005

Interactive and additive influences of Gender, BMI and Apolipoprotein 4 on cognition in children chronically exposed to high concentrations of PM2.5 and ozone. APOE 4 females are at highest risk in Mexico City

scientific article published in July 2016

Interfering of the Reelin/ApoER2/PSD95 Signaling Axis Reactivates Dendritogenesis of Mature Hippocampal Neurons

scientific article

Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts

scientific article published on 07 September 2018

Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability

scientific article published on 13 March 2013

NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB-P, and H3K27ac

scientific article

Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis

scientific article published on October 2008

PSD95 regulates morphological development of adult-born granule neurons in the mouse hippocampus

scientific article published on 30 April 2019

PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors.

scientific article

Pathogenicity of lupus anti-ribosomal P antibodies: role of cross-reacting neuronal surface P antigen in glutamatergic transmission and plasticity in a mouse model.

scientific article published in June 2015

Polycomb PRC2 complex mediates epigenetic silencing of a critical osteogenic master regulator in the hippocampus

scientific article published on 20 May 2016

Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling

scientific article published on 9 June 2015

Receptor compartmentalization and trafficking at glutamate synapses: a developmental proposal

scientific article published in July 2004

Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollution

scientific article published on 04 February 2020

Runx1 and C/EBPβ transcription factors directly up-regulate P2X3 gene transcription

scientific article published on 01 April 2012

Silencing strategies for therapy of SOD1-mediated ALS.

scientific article

Superoxide generation via the NR2B-NMDAR/RasGRF1/NOX2 pathway promotes dendritogenesis

scientific article published on 27 June 2019

Synaptic drive at developing synapses: transient upregulation of kainate receptors

scientific article

The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model

scientific article published on 01 August 2018

Transcription of the pain-related TRPV1 gene requires Runx1 and C/EBPβ factors

scientific article published in April 2013

Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons

scientific article published on 6 June 2013

Variable transcriptional responsiveness of the P2 × 3 receptor gene during CFA-induced inflammatory hyperalgesia

scientific article published on 8 December 2017

Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione

scientific article published on 02 April 2007

Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice

scientific article published on 18 February 2020

αVβ3 Integrin regulates astrocyte reactivity

scientific article published on 29 September 2017

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