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List of works by Ina Schuppe-Koistinen

A generic operational strategy to qualify translational safety biomarkers

scientific article published on 06 May 2011

A longitudinal assessment of miR-122 and GLDH as biomarkers of drug-induced liver injury in the rat.

scientific article published on 15 December 2016

A solution to the 1D NMR alignment problem using an extended generalized fuzzy Hough transform and mode support

scientific article published on 22 July 2009

A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran

scientific article published in December 2009

Analysis of time-related metabolic fluctuations induced by ethionine in the rat.

scientific article published on 30 October 2007

Application of Dolichos biflorus in immunoassay detection of kidney collecting duct biomarkers

scientific article published in August 2010

Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort

scientific article

Correlation network analysis for data integration and biomarker selection

scientific article

Differentiation of human hepatoma cells during confluence as revealed by gene expression profiling

scientific article published on April 2004

Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients

scientific article published on 29 February 2016

Elevated levels of circulating CDH5 and FABP1 in association with human drug-induced liver injury

scientific article

Evaluation of patterns of liver toxicity in patients on antiretroviral and anti-tuberculosis drugs: a prospective four arm observational study in ethiopian patients

scientific article

Feature detection and alignment of hyphenated chromatographic-mass spectrometric data. Extraction of pure ion chromatograms using Kalman tracking

scientific article

Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity

scientific article

Identification of S-glutathionylated cellular proteins during oxidative stress and constitutive metabolism by affinity purification and proteomic analysis

scientific article published on October 2002

Identification of end points relevant to detection of potentially adverse drug reactions

scientific article

Imbalanced kynurenine pathway in schizophrenia

scientific article published on 16 September 2014

Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans

scientific article published on 23 August 2012

Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts

scientific article published on 14 October 2013

Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity.

scientific article published on 16 November 2016

Metabolic fingerprinting of rat urine by LC/MS Part 1. Analysis by hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry

scientific article published on 21 September 2005

Metabolic fingerprinting of rat urine by LC/MS Part 2. Data pretreatment methods for handling of complex data

scientific article

Molecular profiling of hepatotoxicity induced by a aminoguanidine carboxylate in the rat: gene expression profiling

scientific article published in October 2002

Plasma profiling reveals human fibulin-1 as candidate marker for renal impairment

scientific article

Predictive metabolite profiling applying hierarchical multivariate curve resolution to GC-MS data--a potential tool for multi-parametric diagnosis

scientific article

Proof of principle of a generalized fuzzy Hough transform approach to peak alignment of one-dimensional 1H NMR data

scientific article

Real time identification of drug-induced liver injury (DILI) through daily screening of ALT results: a prospective pilot cohort study

scientific article

S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenase: role of thiol oxidation and catalysis by glutaredoxin

scientific article published in January 2002

SOT/EUROTOX Debate: Biomarkers From Blood and Urine Will Replace Traditional Histopathological Evaluation to Determine Adverse Responses ⬇️

scientific article published on October 1, 2012

Screening of biomarkers in rat urine using LC/electrospray ionization-MS and two-way data analysis

scientific article

Second-order peak detection for multicomponent high-resolution LC/MS data

scientific article

Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery

scientific article

Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression

Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression

scientific article

The development of in vitro culture methods to characterize primary T-cell responses to drugs

scientific article published on 13 February 2012

The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model

scientific article published on 25 December 2008

Time-resolved biomarker discovery in 1H-NMR data using generalized fuzzy Hough transform alignment and parallel factor analysis

scientific article

Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact

scientific article published in June 2010

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