List of works - Grace Mugumbate

Anopheles gambiae, Anoga-HrTH hormone, free and bound structure--a nuclear magnetic resonance experiment

scientific article published on 21 February 2013

ChEMBL: towards direct deposition of bioassay data

article by David Mendez et al published 6 November 2018 in Nucleic Acids Research

Drug metabolite generation using a laboratory evolved NADPH independent cytochrome P450: application of in vitro and in silico approaches

scientific article published on March 2013

In silico comparison of antimycobacterial natural products with known antituberculosis drugs

scientific article published on 22 February 2013

Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation

scientific article

Natural Products: A Potential Source of Malaria Transmission Blocking Drugs?

scientific article published on 17 September 2020

Novel anti-plasmodial hits identified by virtual screening of the ZINC database

scientific article

Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen

scientific article (publication date: 16 December 2016)

Open conformation of adipokinetic hormone receptor from the malaria mosquito facilitates hormone binding

scientific article published on 8 September 2010

Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery

scientific article

Strategies and opportunities for promoting bioinformatics in Zimbabwe

scientific article published on 29 November 2018

Structural studies of adipokinetic hormones in water and DPC micelle solution using NMR distance restrained molecular dynamics

scientific article

Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds

scientific article

Synthesis and structure-activity-relationship studies of thiazolidinediones as antiplasmodial inhibitors of the Plasmodium falciparum cysteine protease falcipain-2.

scientific article published on 2 December 2014

TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species.

scientific article

Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach.

scientific article published on 26 September 2017

Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents

scientific article published on 11 July 2013

The relationship between target-class and the physicochemical properties of antibacterial drugs

scientific article

List of works by Grace Mugumbate

Anopheles gambiae, Anoga-HrTH hormone, free and bound structure--a nuclear magnetic resonance experiment

ChEMBL: towards direct deposition of bioassay data

Drug metabolite generation using a laboratory evolved NADPH independent cytochrome P450: application of in vitro and in silico approaches

In silico comparison of antimycobacterial natural products with known antituberculosis drugs

Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation

Natural Products: A Potential Source of Malaria Transmission Blocking Drugs?

Novel anti-plasmodial hits identified by virtual screening of the ZINC database

Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen

Open conformation of adipokinetic hormone receptor from the malaria mosquito facilitates hormone binding

Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery

Strategies and opportunities for promoting bioinformatics in Zimbabwe

Structural studies of adipokinetic hormones in water and DPC micelle solution using NMR distance restrained molecular dynamics

Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds

Synthesis and structure-activity-relationship studies of thiazolidinediones as antiplasmodial inhibitors of the Plasmodium falciparum cysteine protease falcipain-2.

TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species.

Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach.

Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents

The relationship between target-class and the physicochemical properties of antibacterial drugs