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List of works by Gudula Schmidt

A new member of a growing toxin family--Escherichia coli cytotoxic necrotizing factor 3 (CNF3).

scientific article

Activation of RhoA,B,C by Yersinia Cytotoxic Necrotizing Factor (CNFy) induces apoptosis in LNCaP prostate cancer cells

scientific article published on 21 November 2013

Auto-ADP-ribosylation of Pseudomonas aeruginosa ExoS.

scientific article published on 30 January 2002

Bacterial Toxins for Cancer Therapy

scientific article

Change in substrate specificity of cytotoxic necrotizing factor unmasks proteasome-independent down-regulation of constitutively active RhoA.

scientific article published on 12 February 2007

Cleavage of Escherichia coli cytotoxic necrotizing factor 1 is required for full biologic activity

scientific article

Cytotoxic Necrotizing Factors (CNFs)−A Growing Toxin Family

scientific article published on April 8, 2011

Cytotoxic Necrotizing Factors: Rho-Activating Toxins from Escherichia coli

scientific article published on December 2004

Diverse effects of RacV12 on cell transformation by Raf: partial inhibition of morphological transformation versus deregulation of cell cycle control

scientific article

EhRho1, a RhoA-like GTPase of Entamoeba histolytica, is modified by clostridial glucosylating cytotoxins

scientific article

Endoproteolytic processing of RhoA by Rce1 is required for the cleavage of RhoA by Yersinia enterocolitica outer protein T.

scientific article published on March 2006

Engineering Photorhabdus luminescens toxin complex (PTC) into a recombinant injection nanomachine

scientific article published on 20 September 2019

ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways

scientific article

Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1.

scientific article published on 31 May 2013

Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway

scientific article published on 11 May 2010

From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract

scientific article (publication date: 2014)

How to Analyze Bacterial Toxins Targeting Rho GTPases

scientific article published on January 1, 2012

IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation

scientific article

Increased Cell-Matrix Adhesion upon Constitutive Activation of Rho Proteins by Cytotoxic Necrotizing Factors from E. Coli and Y. Pseudotuberculosis

scientific article published on 5 July 2012

Inhibition of Rho A activity causes pemphigus skin blistering

scientific article

Inhibition of cytokinesis by Clostridium difficile toxin B and cytotoxic necrotizing factors--reinforcing the critical role of RhoA in cytokinesis

scientific article published on November 2009

Involvement of Osteocytes in the Action of Toxin

scientific article published on 13 August 2018

Isotype-specific degradation of Rac activated by the cytotoxic necrotizing factor 1.

scientific article

Listeria monocytogenes induced Rac1-dependent signal transduction in endothelial cells

scientific article

Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo-2 cells

scientific article published on 6 July 2016

Lu/BCAM adhesion glycoprotein is a receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1)

scientific article

Modification of plant Rac/Rop GTPase signalling using bacterial toxin transgenes

scientific article

Novel receptors for bacterial protein toxins

scientific article

Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis

scientific article

Photorhabdus luminescens toxins ADP-ribosylate actin and RhoA to force actin clustering

scientific article

Photorhabdus luminescens toxins TccC3 and TccC5: insecticidal ADP-ribosyltransferases that modify threonine and glutamine

scientific article

Pituitary adenylyl cyclase-activating polypeptide 38 reduces astroglial proliferation by inhibiting the GTPase RhoA

scientific journal article

Pleiotropic role of Rac in mast cell activation revealed by a cell permeable Bordetella dermonecrotic fusion toxin

scientific article

Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac.

scientific article published on August 2002

RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

scientific article

Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni

scientific article published on 23 May 2007

Small rho GTPases regulate antigen presentation in dendritic cells

scientific article

Targeting of the actin cytoskeleton by insecticidal toxins from Photorhabdus luminescens

scientific article published on 12 November 2010

The C terminus of YopT is crucial for activity and the N terminus is crucial for substrate binding

scientific article

The Yersinia pseudotuberculosis cytotoxic necrotizing factor (CNFY) selectively activates RhoA.

scientific article published on 3 February 2004

The actin filament architecture: tightly regulated by the cells, manipulated by pathogens. International Titisee Conference on the actin cytoskeleton: from signalling to bacterial pathogenesis

scientific article published on March 2002

The cytotoxic necrotizing factors from Yersinia pseudotuberculosis and from Escherichia coli bind to different cellular receptors but take the same route to the cytosol

scientific article published on 16 April 2007

The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2.

scientific article

The polybasic region of Rho GTPases defines the cleavage by Yersinia enterocolitica outer protein T (YopT).

scientific article

The protein kinase A inhibitor H89 acts on cell morphology by inhibiting Rho kinase

scientific article published in March 2002

Toxin-induced RhoA activity mediates CCL1-triggered signal transducers and activators of transcription protein signaling

scientific article published on 6 February 2012

Yersinia enterocolitica outer protein T (YopT)

scientific article published on January 20, 2011