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List of works by Stephen A. Baldwin

3D reconstruction of mammalian septin filaments

scientific article

A conformationally mobile cysteine residue (Cys-561) modulates Na+ and H+ activation of human CNT3

scientific article published on 11 July 2008

A high-throughput assay of membrane protein stability.

scientific article

A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (Cys-561) in human concentrative nucleoside transporter 3.

scientific article

A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults

scientific article

A urea channel from Bacillus cereus reveals a novel hexameric structure

scientific article published on July 2012

Activation of the Cl- channel ANO1 by localized calcium signals in nociceptive sensory neurons requires coupling with the IP3 receptor

scientific article

Allantoin transport protein, PucI, from Bacillus subtilis: evolutionary relationships, amplified expression, activity and specificity ⬇️

scientific article

Allelic isoforms of the H+/nucleoside co-transporter (CaCNT) from Candida albicans reveal separate high- and low-affinity transport systems for nucleosides

scientific article published in November 2004

An ancient prevertebrate Na+-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti).

scientific article

At-hatch administration of probiotic to chickens can introduce beneficial changes in gut microbiota

scientific article published on 23 March 2018

Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3.

scientific article

Characterisation of the DAACS Family Escherichia coli Glutamate/Aspartate-Proton Symporter GltP Using Computational, Chemical, Biochemical and Biophysical Methods

scientific article published on 26 December 2016

Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells

scientific article

Characterization of the transport mechanism and permeant binding profile of the uridine permease Fui1p of Saccharomyces cerevisiae

scientific article

Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation.

scientific article published on May 2005

Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan

scientific article published on 21 April 2003

Comparison of the interaction of uridine, cytidine, and other pyrimidine nucleoside analogues with recombinant human equilibrative nucleoside transporter 2 (hENT2) produced in Saccharomyces cerevisiae

scientific article published in January 2002

Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3

scientific article published on 20 April 2009

Conserved glutamate residues are critically involved in Na+/nucleoside cotransport by human concentrative nucleoside transporter 1 (hCNT1).

scientific article published on 17 August 2007

Constitutive protein secretion from the trans-Golgi network to the plasma membrane

scientific article

Control of glutamatergic neurotransmission in the rat spinal dorsal horn by the nucleoside transporter ENT1

scientific journal article

Creating a regional pediatric medical disaster preparedness network: imperative and issues

scientific article

Cysteine-accessibility analysis of transmembrane domains 11-13 of human concentrative nucleoside transporter 3.

scientific article published in March 2006

Defining topological features of membrane proteins by nanoelectrospray ionisation mass spectrometry

scientific article published in February 2010

Differential expression of human equilibrative nucleoside transporter 1 (hENT1) protein in the Reed-Sternberg cells of Hodgkin's disease

scientific article

Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH.

scientific article published on 27 July 2006

Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human ⬇️

scientific article published on 6 June 2015

Dynamic action of the Sec machinery during initiation, protein translocation and termination revealed by single molecule fluorescence

Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes

scientific article

Equilibrative nucleoside transporters of Arabidopsis thaliana. cDNA cloning, expression pattern, and analysis of transport activities

scientific article

Equipping a Research Scale Fermentation Laboratory for Production of Membrane Proteins

article

Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation

scientific article (publication date: 12 July 2002)

Functional and structural characterization of the first prokaryotic member of the L-amino acid transporter (LAT) family: a model for APC transporters

scientific article published on 6 March 2007

Functional characterization of a H+/nucleoside co-transporter (CaCNT) from Candida albicans, a fungal member of the concentrative nucleoside transporter (CNT) family of membrane proteins

scientific article

Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes

scientific article published on 8 February 2005

Functional redundancy of two nucleoside transporters of the ENT family (CeENT1, CeENT2) required for development of Caenorhabditis elegans

scientific article published in July 2004

How to move an amphipathic molecule across a lipid bilayer: different mechanisms for different ABC transporters? ⬇️

scientific article

Human concentrative nucleoside transporter 3 is a determinant of fludarabine transportability and cytotoxicity in human renal proximal tubule cell cultures

scientific article published on 24 May 2008

Identification and functional characterization of variants in human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), arising from single nucleotide polymorphisms in coding regions of the hCNT3 gene

scientific article published in March 2005

Identification and mutational analysis of amino acid residues involved in dipyridamole interactions with human and Caenorhabditis elegans equilibrative nucleoside transporters

scientific article

Insights into the Molecular Mechanisms Underlying Mammalian P2X7 Receptor Functions and Contributions in Diseases, Revealed by Structural Modeling and Single Nucleotide Polymorphisms

scientific article

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

scientific article

Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface

scientific article published on 16 July 2003

Investigation of the structure and function of a Shewanella oneidensis arsenical-resistance family transporter

scientific article published in December 2008

Large-scale preparation of bacterial cell membranes by tangential flow filtration.

scientific article

Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney

scientific article

Localization of the NBMPR-sensitive equilibrative nucleoside transporter, ENT1, in the rat dorsal root ganglion and lumbar spinal cord

scientific article

Malleability of the folding mechanism of the outer membrane protein PagP: parallel pathways and the effect of membrane elasticity

scientific article published on 8 January 2012

Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis

scientific article

Membrane Transport Proteins: The Proton-Dependent Oligopeptide Transporter Family

Methyl-beta-cyclodextrin stimulates glucose uptake in Clone 9 cells: a possible role for lipid rafts ⬇️

scientific article published on March 1, 2004

Modeling, docking, and simulation of the major facilitator superfamily

scientific article

Molecular Biology of Nucleoside Transporters and their Distributions and Functions in the Brain ⬇️

scientific article published on January 1, 2011

Molecular biology and regulation of nucleoside and nucleobase transporter proteins in eukaryotes and prokaryotes

scientific article

Mutation of Residue 33 of Human Equilibrative Nucleoside Transporters 1 and 2 Alters Sensitivity to Inhibition of Transport by Dilazep and Dipyridamole ⬇️

scientific article published on October 31, 2001

Mutation of Trp29 of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity

scientific article

Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkers ⬇️

scientific article

Nucleobase Transport by Human Equilibrative Nucleoside Transporter 1 (hENT1) ⬇️

scientific article published on July 27, 2011

Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy ⬇️

scientific article published on October 20, 2003

Nucleoside transport as a potential target for chemotherapy in malaria

scientific article published on January 2007

Nucleoside transporters: from scavengers to novel therapeutic targets

scientific article published on 3 July 2006

PIMS sequencing extension: a laboratory information management system for DNA sequencing facilities

scientific article

Phosphate concentration and arbuscular mycorrhizal colonisation influence the growth, yield and expression of twelve PHT1 family phosphate transporters in foxtail millet (Setaria italica). ⬇️

scientific article

Pi sensing and signalling: from prokaryotic to eukaryotic cells ⬇️

scientific article published on June 2016

Plant Peroxisomal ABC Transporters: Flexible and Unusual

scientific article published in 2014

Polarized distribution of nucleoside transporters in rat brain endothelial and choroid plexus epithelial cells

scientific article published in September 2005

Probing metal ion substrate-binding to the E. coli ZitB exporter in native membranes by solid state NMR.

scientific article published in December 2008

Pseudo half-molecules of the ABC transporter, COMATOSE, bind Pex19 and target to peroxisomes independently but are both required for activity

scientific article published on 16 June 2012

Purification and properties of the Escherichia coli nucleoside transporter NupG, a paradigm for a major facilitator transporter sub-family

scientific article published on September 2004

Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis

scientific article

Relative substrate affinities of wild-type and mutant forms of the Escherichia coli sugar transporter GalP determined by solid-state NMR.

scientific article

Reliable scale-up of membrane protein over-expression by bacterial auto-induction: from microwell plates to pilot scale fermentations.

scientific article

Renal nucleoside transporters: physiological and clinical implications

scientific article published on December 2006

Residue 33 of human equilibrative nucleoside transporter 2 is a functionally important component of both the dipyridamole and nucleoside binding sites

scientific article

Residues 155 and 348 contribute to the determination of P2X7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms

scientific article

Retraction of "Characterization of the Escherichia coli Concentrative Nucleoside Transporter NupC Using Computational, Biochemical, and Biophysical Methods".

scientific article

Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions

scientific article

Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling

scientific article published in February 2007

Structural biology: Bundles of insights into sugar transporters

scientific article published in October 2012

Structure and function of the bacterial heterodimeric ABC transporter CydDC: stimulation of ATPase activity by thiol and heme compounds. ⬇️

scientific article

Studies of nucleoside transporters using novel autofluorescent nucleoside probes

scientific article published in January 2006

Substituted cysteine accessibility method analysis of human concentrative nucleoside transporter hCNT3 reveals a novel discontinuous region of functional importance within the CNT family motif (G/A)XKX3NEFVA(Y/M/F).

scientific article published on 20 April 2009

Sugar-cation symport systems in bacteria

scientific article published on January 1, 1992

The Arabidopsis peroxisomal ABC transporter, comatose, complements the Saccharomyces cerevisiae pxa1 pxa2Delta mutant for metabolism of long-chain fatty acids and exhibits fatty acyl-CoA-stimulated ATPase activity ⬇️

scientific article published on 21 July 2010

The N-terminal helix is a post-assembly clamp in the bacterial outer membrane protein PagP.

scientific article

The Nucleobase-Cation-Symport-1 Family of Membrane Transport Proteins

The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics

scientific article published on 3 May 2005

The conservation of phosphate-binding residues among PHT1 transporters suggests that distinct transport affinities are unlikely to result from differences in the phosphate-binding site ⬇️

scientific article published on October 2016

The equilibrative nucleoside transporter family, SLC29

scientific article (publication date: February 2004)

The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29.

scientific article published on April 2013

The nucleoside transport proteins, NupC and NupG, from Escherichia coli: specific structural motifs necessary for the binding of ligands

scientific article

The oligomeric state and arrangement of the active bacterial translocon

scientific article

The role of nucleoside transporters in cancer chemotherapy with nucleoside drugs

scientific article published on March 2007

The sodium-dependent D-glucose transport protein of Helicobacter pylori

scientific article published in January 2009

The transition state for folding of an outer membrane protein

scientific article

The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy. ⬇️

scientific article

This is about the in and the out.

scientific article published in June 2013

Topology-informed strategies for the overexpression and purification of membrane proteins

scientific article published in September 2007

Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3.

scientific article

Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H(+) cotransporter (NupC) produced in Xenopus laevis oocytes

scientific article

Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation ⬇️

scientific article published on 16 May 2016

Uridine binding and transportability determinants of human concentrative nucleoside transporters

scientific article

Uridine binding motifs of human concentrative nucleoside transporters 1 and 3 produced in Saccharomyces cerevisiae

scientific article

Uridine recognition motifs of human equilibrative nucleoside transporters 1 and 2 produced in Saccharomyces cerevisiae

scientific article published in January 2004

Use of Escherichia coli for the Production and Purification of Membrane Proteins ⬇️

scientific article published on January 1, 2013

Use of molecular modelling to probe the mechanism of the nucleoside transporter NupG ⬇️

scientific article published on December 21, 2012

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