Search filters

List of works by Benita Katzenellenbogen

14-3-3ζ as a predictor of early time to recurrence and distant metastasis in hormone receptor-positive and -negative breast cancers ⬇️

scientific article published on December 28, 2012

A MicroRNA196a2* and TP63 circuit regulated by estrogen receptor-α and ERK2 that controls breast cancer proliferation and invasiveness properties

scientific article published on 19 December 2012

A human estrogen receptor (ER)alpha mutation with differential responsiveness to nonsteroidal ligands: novel approaches for studying mechanism of ER action

scientific article published on May 2008

A repressive role for prohibitin in estrogen signaling.

scientific article

Activation of ERα is necessary for estradiol's anorexigenic effect in female rats ⬇️

scientific article published on August 31, 2010

Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression

scientific article published on August 2003

Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells.

scientific article published on 28 June 2017

Allosteric control of ligand selectivity between estrogen receptors alpha and beta: implications for other nuclear receptors

scientific article published on February 2004

Alteration of large-scale chromatin structure by estrogen receptor

scientific article

Analogs of methyl-piperidinopyrazole (MPP): antiestrogens with estrogen receptor alpha selective activity

scientific article published on 6 November 2008

Antagonists selective for estrogen receptor alpha

scientific article published in March 2002

Aryl hydrocarbon receptor modulation of estrogen receptor α-mediated gene regulation by a multimeric chromatin complex involving the two receptors and the coregulator RIP140.

scientific article published on 9 November 2011

Bibenzyl- and stilbene-core compounds with non-polar linker atom substituents as selective ligands for estrogen receptor beta

scientific article

Biomedicine. Defining the "S" in SERMs

scientific article

Bridged bicyclic cores containing a 1,1-diarylethylene motif are high-affinity subtype-selective ligands for the estrogen receptor

scientific article published in April 2003

Characterization of the biological roles of the estrogen receptors, ERalpha and ERbeta, in estrogen target tissues in vivo through the use of an ERalpha-selective ligand

scientific article published in November 2002

Characterization of the interactions of estrogen receptor and MNAR in the activation of cSrc

scientific article

Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs).

scientific article

Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers

scientific article published on 24 August 2020

Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity

scientific article

Contrasting activities of estrogen receptor beta isoforms in triple negative breast cancer

scientific article published on 01 October 2020

Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain

scientific article published on 01 May 2017

Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity

scientific article

DNA shuffling method for generating estrogen receptor alpha and beta chimeras in yeast

scientific article published on 01 February 2003

Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

scientific article

Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland

scientific article published on 10 November 2015

Differential estradiol and selective estrogen receptor modulator (SERM) regulation of Keratin 13 gene expression and its underlying mechanism in breast cancer cells

scientific article

Differential utilization of nuclear and extranuclear receptor signaling pathways in the actions of estrogens, SERMs, and a tissue-selective estrogen complex (TSEC).

scientific article published on 12 December 2015

Directed evolution of human estrogen receptor variants with significantly enhanced androgen specificity and affinity

scientific article

Distinct roles for AF-1 and -2 of ER-alpha in regulation of MMP-13 promoter activity

scientific article

Distinctive actions of membrane-targeted versus nuclear localized estrogen receptors in breast cancer cells

scientific article

Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis

scientific article published on January 2015

Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands

scientific article

Endocrine Society 2014 Laureate Awards

scientific article published in October 2014

Endocrine treatment in breast cancer: Cure, resistance and beyond

scientific article published on 7 September 2016

Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta

scientific article published in March 2004

Erratum: Full antagonism of the estrogen receptor without a prototypical ligand side chain

scientific article published on 01 May 2017

Estrogen Receptor-β Modulation of the ERα-p53 Loop Regulating Gene Expression, Proliferation, and Apoptosis in Breast Cancer.

scientific article published on 2 June 2017

Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding

scientific article

Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action

scientific article published on 23 November 2005

Estrogen down-regulation of the corepressor N-CoR: mechanism and implications for estrogen derepression of N-CoR-regulated genes

scientific article

Estrogen receptor alpha represses transcription of early target genes via p300 and CtBP1

scientific article

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.

scientific article published on 2 February 2016

Estrogen receptor inducibility of the human Na+/H+ exchanger regulatory factor/ezrin-radixin-moesin binding protein 50 (NHE-RF/EBP50) gene involving multiple half-estrogen response elements

scientific article published on August 2002

Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts

scientific article published on April 2002

Estrogen receptor regulation of carbonic anhydrase XII through a distal enhancer in breast cancer

scientific article published in May 2008

Estrogen receptor regulation of quinone reductase in breast cancer: implications for estrogen-induced breast tumor growth and therapeutic uses of tamoxifen

scientific article

Estrogen receptor β ligands: recent advances and biomedical applications.

scientific article

Estrogen receptor-mediated transcription involves the activation of multiple kinase pathways in neuroblastoma cells.

scientific article published on 10 October 2013

Estrogen receptor-α and aryl hydrocarbon receptor involvement in the actions of botanical estrogens in target cells.

scientific article published on 16 August 2016

Estrogen regulation of the glucuronidation enzyme UGT2B15 in estrogen receptor-positive breast cancer cells

scientific article published on 11 May 2006

Estrogen-induced CCN1 is critical for establishment of endometriosis-like lesions in mice

scientific article

Estrogen-occupied estrogen receptor represses cyclin G2 gene expression and recruits a repressor complex at the cyclin G2 promoter

scientific article

Estrogen-regulated gene networks in human breast cancer cells: involvement of E2F1 in the regulation of cell proliferation

scientific article published on 5 June 2007

Estrogen-regulated prohibitin is required for mouse uterine development and adult function.

scientific article

Estrogenic diazenes: heterocyclic non-steroidal estrogens of unusual structure with selectivity for estrogen receptor subtypes

scientific article published in February 2003

Estrogens and androgens inhibit association of RANKL with the pre-osteoblast membrane through post-translational mechanisms

scientific article published on 18 February 2017

Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells

scientific article published on 23 August 2014

Expression of steroid hormone receptors in BRCA1-associated ovarian carcinomas

scientific article published in April 2005

Extranuclear estrogen receptor-alpha stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

scientific article

Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome

scientific article published on July 2006

General esterases of silkmoth moulting fluid: Preliminary characterization

Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo

scientific article

Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation

scientific article

Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection

scientific article

Genomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs

scientific article

Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland

scientific journal article

Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model

scientific article

Highly sensitive quantitative imaging for monitoring single cancer cell growth kinetics and drug response

scientific article

Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells

scientific article published on 29 June 2006

In memoriam: Jack Gorski (1931-2006).

scientific article

Indazole estrogens: highly selective ligands for the estrogen receptor beta.

scientific article published on February 2005

Integration of molecular profiling and chemical imaging to elucidate fibroblast-microenvironment impact on cancer cell phenotype and endocrine resistance in breast cancer

scientific article (publication date: 2014)

Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators

scientific article published on 25 April 2017

Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators

scientific article published on 18 June 2013

Isocoumarins as estrogen receptor beta selective ligands: Isomers of isoflavone phytoestrogens and their metabolites

scientific article published on 15 August 2005

Kinase-specific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity

scientific article published on 31 August 2006

Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities

scientific article

Ligand Accessibility and Bioactivity of a Hormone-Dendrimer Conjugate Depend on pH and pH History

scientific article published on 17 July 2015

Lipin1 regulation by estrogen in uterus and liver: implications for diabetes and fertility

scientific article published on 26 April 2007

Localization of androgen and estrogen receptors in adult male mouse reproductive tract

scientific article

MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression.

scientific article published on 13 February 2017

Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens

scientific article published on 23 July 2013

Mechanistic Aspects of Estrogen Receptor Activation Probed with Constitutively Active Estrogen Receptors: Correlations with DNA and Coregulator Interactions and Receptor Conformational Changes

Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications.

scientific article

Metabolite ligands of estrogen receptor-beta reduce primate coronary hyperreactivity

scientific article

Modulation of estrogen receptor activity by selective coregulators

scientific article

Molecular basis for the subtype discrimination of the estrogen receptor-beta-selective ligand, diarylpropionitrile

scientific article

Molecular cloning of porcine estrogen receptor-beta complementary DNAs and developmental expression in periimplantation embryos

scientific article published on March 2002

Monoaryl-substituted salicylaldoximes as ligands for estrogen receptor beta

scientific article published on 13 February 2008

Multiple Beneficial Roles of Repressor of Estrogen Receptor Activity (REA) in Suppressing the Progression of Endometriosis

scientific article published on 14 December 2015

NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses

scientific article

Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice

scientific article

Non-nuclear estrogen receptor alpha activation in endothelium reduces cardiac ischemia-reperfusion injury in mice.

scientific article published on 27 April 2017

Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice

scientific article

Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass

scientific article published on 26 February 2013

Nonnuclear Estrogen Receptor Activation Improves Hepatic Steatosis in Female Mice.

scientific article published on 23 August 2016

Novel estrogen receptor ligands based on an anthranylaldoxime structure: role of the phenol-type pseudocycle in the binding process

scientific article published in September 2003

Novel roles for ERK5 and cofilin as critical mediators linking ERα-driven transcription, actin reorganization, and invasiveness in breast cancer

scientific article

Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors

scientific article published on 10 July 2008

Phenethyl pyridines with non-polar internal substituents as selective ligands for estrogen receptor beta

scientific article

Phosphorylation by p38 Mitogen-Activated Protein Kinase Promotes Estrogen ReceptorαTurnover and Functional Activity via the SCFSkp2Proteasomal Complex ⬇️

scientific article published on March 19, 2012

Post-transcriptional regulation of chemokine receptor CXCR4 by estrogen in HER2 overexpressing, estrogen receptor-positive breast cancer cells

scientific article published on 19 September 2008

Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype

scientific article published on 10 July 2003

Protective Hematopoietic Effect of Estrogens in a Mouse Model of Thrombosis: Respective Roles of Nuclear Versus Membrane Estrogen Receptor α

scientific article

Protein kinase A activation of estrogen receptor alpha transcription does not require proteasome activity and protects the receptor from ligand-mediated degradation

scientific article

Proteinases of silkmoth moulting fluid: Physical and catalytic properties

Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity

scientific article

Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97)

scientific article

Repressor of estrogen receptor activity (REA) is essential for mammary gland morphogenesis and functional activities: studies in conditional knockout mice

scientific article

Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ERbeta in the uterus

scientific article

Reversal of endocrine resistance in breast cancer: interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis ⬇️

scientific article published on June 29, 2011

Science Signaling podcast for 24 May 2016: Designer estrogens

scientific article published on 24 May 2016

Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells

scientific article published on February 2004

Selective recognition of distinct classes of coactivators by a ligand-inducible activation domain

scientific article published on March 2004

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

scientific article

Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors

scientific article

Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains.

scientific article published on January 2007

Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds

scientific article published on 29 November 2019

Suppression of Tumor Growth, Metastasis, and Signaling Pathways by Reducing FOXM1 Activity in Triple Negative Breast Cancer

scientific article published on 19 September 2020

Suppression of breast cancer metastasis and extension of survival by a new antiestrogen in a preclinical model driven by mutant estrogen receptors

scientific article published on 10 April 2020

Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: estrogen antagonists of unusual structure

scientific article published on November 2005

Targeting Metabolic Adaptations in the Breast Cancer–Liver Metastatic Niche Using Dietary Approaches to Improve Endocrine Therapy Efficacy

scientific article published in 2022

The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle Cells.

scientific article

The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits prostate cancer cell migration through activation of the estrogen receptor beta subtype

scientific article published on June 2005

The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro

scientific article published on 9 December 2015

The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization

scientific article published on 7 February 2013

The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells ⬇️

scientific article published on August 25, 2011

The forkhead transcription factor FOXM1 promotes endocrine resistance and invasiveness in estrogen receptor-positive breast cancer by expansion of stem-like cancer cells

scientific article

The roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cells

scientific journal article

Therapeutic targeting in the estrogen receptor hormonal pathway

scientific article published on February 2004

Thyroid hormone can increase estrogen-mediated transcription from a consensus estrogen response element in neuroblastoma cells.

scientific article

Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) alpha or ERbeta in human osteosarcoma cells: distinct and common target genes for these receptors

scientific article (publication date: July 2004)

Transcriptomic analysis identifies gene networks regulated by estrogen receptor α (ERα) and ERβ that control distinct effects of different botanical estrogens

scientific article

Uterine Development and Fertility Are Dependent on Gene Dosage of the Nuclear Receptor Coregulator REA ⬇️

scientific article published on May 14, 2012

Whole-Genome Cartography of Estrogen Receptorα Binding Sites

Whole-genome cartography of estrogen receptor alpha binding sites

scientific article

Paulina is supported by:

About Paulina

Help