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List of works by Hans Adomat

A novel communication role for CYP17A1 in the progression of castration-resistant prostate cancer

scientific article published on June 2009

A novel oral dosage formulation of the ginsenoside aglycone protopanaxadiol exhibits therapeutic activity against a hormone-insensitive model of prostate cancer ⬇️

scientific article published on June 1, 2012

Abiraterone inhibits 1α,25-dihydroxyvitamin D3 metabolism by CYP3A4 in human liver and intestine in vitro

scientific article

Age-dependent alterations of the kynurenine pathway in the YAC128 mouse model of Huntington disease

scientific article published on 15 July 2013

Anticancer activity of a novel selective CYP17A1 inhibitor in preclinical models of castrate-resistant prostate cancer

scientific article

Arachidonic acid activation of intratumoral steroid synthesis during prostate cancer progression to castration resistance

scientific article published on February 2010

Assessing the therapeutic and toxicological effects of cesium chloride following administration to nude mice bearing PC-3 or LNCaP prostate cancer xenografts

scientific article

Calcitriol and 20(S)-protopanaxadiol synergistically inhibit growth and induce apoptosis in human prostate cancer cells

scientific article published on 17 December 2015

Capsaicin reduces the metastatic burden in the transgenic adenocarcinoma of the mouse prostate model

scientific article published on 5 June 2015

Capsaicin: a novel radio-sensitizing agent for prostate cancer

scientific article published on 13 October 2014

Characterization of a new class of androgen receptor antagonists with potential therapeutic application in advanced prostate cancer

scientific article published on 12 August 2013

Discovery of small-molecule inhibitors selectively targeting the DNA-binding domain of the human androgen receptor

scientific article

Effect of noncompetitive proteasome inhibition on bortezomib resistance

scientific article

Evidence for contamination of herbal erectile dysfunction products with phosphodiesterase type 5 inhibitors

scientific article published in August 2005

Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins Derived from a Panel of Prostate Cell Lines with Distinct AR Phenotypes ⬇️

scientific article published on June 21, 2012

Genistein Increases Epidermal Growth Factor Receptor Signaling and Promotes Tumor Progression in Advanced Human Prostate Cancer ⬇️

scientific article published on May 16, 2011

Hypoxia in the androgen-dependent Shionogi model for prostate cancer at three stages.

scientific article

Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor

scientific article published on 3 November 2015

Identification of a potent antiandrogen that targets the BF3 site of the androgen receptor and inhibits enzalutamide-resistant prostate cancer

scientific article

Identification of human cytochrome P450 enzymes involved in the hepatic and intestinal biotransformation of 20(S)-protopanaxadiol

scientific article

Investigating contamination of phytotherapy products for benign prostatic hyperplasia with alpha-blockers and 5alpha-reductase inhibitors

scientific article published on 19 March 2010

Next-generation steroidogenesis inhibitors, dutasteride and abiraterone, attenuate but still do not eliminate androgen biosynthesis in 22RV1 cells in vitro

scientific article published on 6 September 2014

Pomegranate extracts impact the androgen biosynthesis pathways in prostate cancer models in vitro and in vivo

scientific article published on 22 February 2014

Pre-clinical evaluation of Rh2 in PC-3 human xenograft model for prostate cancer in vivo: formulation, pharmacokinetics, biodistribution and efficacy

scientific article published on 20 March 2009

Protein profiling of microdissected prostate tissue links growth differentiation factor 15 to prostate carcinogenesis

scientific article

The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer

scientific article published on 29 July 2015

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