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List of works by Audun Stubhaug

9 Post-operative analgesic trials: some important issues

A new method to evaluate central sensitization to pain following surgery. Effect of ketamine ⬇️

scientific article published on January 1, 1997

A new treatable chronic pain diagnosis? Flank pain caused by entrapment of posterior cutaneous branch of intercostal nerves, lateral ACNES coined LACNES.

scientific article published on 25 October 2017

A new treatment principle for neuropathic pain? Approved oncologic drugs: Epidermal growth factor receptor (EGFR) inhibitors dramatically relieve severe neuropathic pain in a case series

A population-based study of quantitative sensory testing in adolescents with and without chronic pain

scientific article published on 15 September 2016

A randomized double-blind controlled trial of intra-annular radiofrequency thermal disc therapy--a 12-month follow-up

scientific article

A throat infection with rapid deterioration

scientific article published in August 2002

A tonic heat test stimulus yields a larger and more reliable conditioned pain modulation effect compared to a phasic heat test stimulus

scientific article published on 15 November 2017

Adding propacetamol to ketorolac increases the tolerance to painful pressure

scientific article published on April 2006

Additive analgesic effect of codeine and paracetamol can be detected in strong, but not moderate, pain after Caesarean section. Baseline pain-intensity is a determinant of assay-sensitivity in a postoperative analgesic trial

scientific article published on April 1996

Advances in understanding and treatment of opioid-induced-bowel-dysfunction, opioid-induced-constipation in particular: Nordic recommendations based on multi-specialist input

scientific article published on 9 March 2016

Analgesia and sedation of mechanically ventilated patients – a national survey of clinical practice ⬇️

scientific article published on September 26, 2011

Assessment of pain

scientific article

Association between intracranial pulse pressure levels and brain energy metabolism in a patient with an aneurysmal subarachnoid haemorrhage

scientific article published on 20 August 2007

Burden of disease is often aggravated by opioid treatment of chronic pain patients: Etiology and prevention

scientific article published on 16 September 2014

C-reactive protein and cold-pressor tolerance in the general population: the Tromsø Study

scientific article published on 31 March 2017

CNS-mechanisms contribute to chronification of pain

scientific article published on 4 April 2017

Can opioids prevent post-operative chronic pain?

scientific article

Cancer-pain intractable to high-doses systemic opioids can be relieved by intraspinal local anaesthetic plus an opioid and an alfa2-adrenoceptor agonist

scientific article published on 27 June 2017

Cardiac arrest after intravenous metoclopramide - a case of five repeated injections of metoclopramide causing five episodes of cardiac arrest

scientific article

Central dysesthesia pain after traumatic spinal cord injury is dependent on N-methyl-D-aspartate receptor activation

scientific article published in December 1995

Changes in blood pressure and cardiac output during cesarean delivery: the effects of oxytocin and carbetocin compared with placebo

scientific article published in September 2013

Chronic Abdominal Pain and Symptoms 5 Years After Gastric Bypass for Morbid Obesity

scientific article published on 27 December 2016

Chronic compartment syndrome is an under-recognized cause of leg-pain

scientific article published on 6 May 2016

Chronic pain and sensory changes after augmentation mammoplasty: Long term effects of preincisional administration of methylprednisolone

Chronic pain-related changes in cardiovascular regulation and impact on comorbid hypertension in a general population: the Tromsø study

scientific article

Cognitive Effects of Perioperative Pregabalin: Secondary Exploratory Analysis of a Randomized Placebo-controlled Study

scientific article published on 01 January 2019

Cold allodynia and hyperalgesia in neuropathic pain: the effect of N-methyl-D-aspartate (NMDA) receptor antagonist ketamine--a double-blind, cross-over comparison with alfentanil and placebo

scientific article published in February 2003

Comparison of intracranial pressure measured simultaneously within the brain parenchyma and cerebral ventricles

scientific article published on 3 October 2006

Comparison of tramadol with morphine for post-operative pain following abdominal surgery

scientific article published on 01 July 1996

Complex Regional Pain Syndrome (CRPS) after viper-bite in a pregnant young woman: Pathophysiology and treatment options

scientific article

Conditioned pain modulation: A useful test paradigm in research and in clinical practice

Continuous invasive blood pressure and cardiac output monitoring during cesarean delivery: a randomized, double-blind comparison of low-dose versus high-dose spinal anesthesia with intravenous phenylephrine or placebo infusion

scientific article

Continuous subcutaneous administration of the N-methyl-D-aspartic acid (NMDA) receptor antagonist ketamine in the treatment of post-herpetic neuralgia

scientific article published on May 1995

Current threshold for nerve stimulation depends on electrical impedance of the tissue: a study of ultrasound-guided electrical nerve stimulation of the median nerve

scientific article published in April 2009

Detecting postoperative urinary retention with an ultrasound scanner

scientific article published in March 2002

Differential effects of osmotherapy on static and pulsatile intracranial pressure

scientific article published in August 2008

Difficult drug reimbursement system for pain patients

scientific article published in January 2013

Effective pain relief from intra-articular saline with or without morphine 2 mg in patients with moderate-to-severe pain after knee arthroscopy: a randomized, double-blind controlled clinical study

scientific article

Effects of COX inhibition on experimental pain and hyperalgesia during and after remifentanil infusion in humans

scientific article published on 10 March 2011

Electrical nerve stimulation or ultrasound guidance for lateral sagittal infraclavicular blocks: a randomized, controlled, observer-blinded, comparative study

scientific article published in June 2008

Endocrinopathies in women during opioid therapy cause loss of androgens, fatigue, listlessness, loss of libido and quality of life: stop prescribing opioids or follow the 2016 Centers for Disease Control and Prevention guidelines?

scientific article

Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

scientific article published in October 2016

Experimental comparison of parametric versus nonparametric analyses of data from the cold pressor test

scientific article published on 20 March 2015

From intracranial pressure to intracranial pressure wave-guided intensive care management of a patient with an aneurysmal subarachnoid haemorrhage

scientific article published in April 2007

Gabapentin in traumatic nerve injury pain: a randomized, double-blind, placebo-controlled, cross-over, multi-center study

scientific article

Gender is a confounding factor in pain trials: women report more pain than men after arthroscopic surgery

scientific article published in December 2004

Genetic variation in P2RX7 and pain tolerance

scientific article published on 20 February 2018

Glucocorticoids reduce acute postoperative pain

scientific article

Gradual withdrawal of remifentanil infusion may prevent opioid-induced hyperalgesia

scientific article

Haemodynamic effects of oxytocin in women with severe preeclampsia

scientific article

Haemodynamic effects of repeated doses of oxytocin during Caesarean delivery in healthy parturients

scientific article published on 5 June 2009

Health-related quality of life in intensive care survivors: Associations with social support, comorbidity, and pain interference.

scientific article published on 25 June 2018

Hemodynamic effects of oxytocin during cesarean delivery

scientific article published on 21 August 2006

Hypertension prevalence and diminished blood pressure-related hypoalgesia in individuals reporting chronic pain in a general population: the Tromsø study.

scientific article

Hypertonic saline (7.2%) in 6% hydroxyethyl starch reduces intracranial pressure and improves hemodynamics in a placebo-controlled study involving stable patients with subarachnoid hemorrhage*

Ibuprofen plus codeine, ibuprofen, and placebo in a single- and multidose cross-over comparison for coxarthrosis pain

scientific article published on 01 September 1992

Importance of early diagnosis of complex regional pain syndrome (CRPS-1 and C RPS-2): Delayed diagnosis of CRPS is a major problem

scientific article published on 19 December 2015

Important development: Extended Acute Pain Service for patients at high risk of chronic pain after surgery

scientific article published on 7 May 2016

Increased pain sensitivity among adults reporting irritable bowel syndrome symptoms in a large population-based study ⬇️

scientific article published on December 5, 2012

Indirect calorimetry reveals that better monitoring of nutrition therapy in pediatric intensive care is needed

scientific article published on 19 November 2013

Individual differences in pain sensitivity: genetic and environmental contributions

scientific article published on 9 August 2007

Intensive care survivor-reported symptoms: a longitudinal study of survivors' symptoms

scientific article published on 15 December 2017

Intra-Articular Morphine 5 mg After Knee Arthroscopy Does Not Produce Significant Pain Relief When Administered to Patients With Moderate to Severe Pain via an Intra-Articular Catheter

article published in 2006

Intra-Articular Morphine in Acute Pain Trials

Intra-articular (IA) catheter administration of postoperative analgesics. A new trial design allows evaluation of baseline pain, demonstrates large variation in need of analgesics, and finds no analgesic effect of IA ketamine compared with IA saline

scientific article

Intra-articular morphine 5 mg after knee arthroscopy does not produce significant pain relief when administered to patients with moderate to severe pain via an intra-articular catheter

scientific article published on November 2006

Intra-articular morphine for pain relief after knee arthroscopy

scientific article

Investigating the Burden of Chronic Pain: An Inflammatory and Metabolic Composite

scientific article published on 02 June 2016

Ketamine, an NMDA receptor antagonist, suppresses spatial and temporal properties of burn-induced secondary hyperalgesia in man: a double-blind, cross-over comparison with morphine and placebo ⬇️

scientific article published on August 1, 1997

Knee osteoarthritis patients with intact pain modulating systems may have low risk of persistent pain after knee joint replacement

article by Audun Stubhaug & Harald Breivik published 1 January 2015 in Scandinavian Journal of Pain

Lack of analgesic effect of 50 and 100 mg oral tramadol after orthopaedic surgery: a randomized, double-blind, placebo and standard active drug comparison

scientific article published in July 1995

Les corticoïdes diminuent-ils la douleur et les nausées–vomissements postopératoires ?

Local treatment with the N-methyl-D-aspartate receptor antagonist ketamine, inhibit development of secondary hyperalgesia in man by a peripheral action

scientific article published in May 1997

Long-term treatment of chronic neuropathic pain with the NMDA (N-methyl-D-aspartate) receptor antagonist ketamine

scientific article published in March 1997

Low-dose versus a Higher-dose Bupivacaine Spinal Anesthesia for Cesarean Delivery

Management of acute postoperative pain: still a long way to go!

scientific article published on 13 May 2008

Mapping of punctuate hyperalgesia around a surgical incision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery ⬇️

scientific article published on October 1, 1997

Mental and somatic co-morbidities in chronic orofacial pain conditions: Pain patients in need of multiprofessional team approach

scientific article published on 01 October 2011

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

scientific article

Methylprednisolone and ketorolac rapidly reduce hyperalgesia around a skin burn injury and increase pressure pain thresholds

scientific article

Methylprednisolone intravenously 1 day after surgery has sustained analgesic and opioid-sparing effects

scientific article

Methylprednisolone reduces pain, emesis, and fatigue after breast augmentation surgery: a single-dose, randomized, parallel-group study with methylprednisolone 125 mg, parecoxib 40 mg, and placebo

scientific article published in February 2006

Mirror-therapy: An important tool in the management of Complex Regional Pain Syndrome (CRPS)

Moderate-to-severe pain after knee arthroscopy is relieved by intraarticular saline: a randomized controlled trial

scientific article

Pain Tolerance in Persons With Recognized and Unrecognized Myocardial Infarction: A Population-Based, Cross-Sectional Study

scientific article published on 21 December 2016

Pain and disability 1 year after knee arthroscopic procedures

scientific article published in March 2008

Pain and pain tolerance in whiplash-associated disorders: A population-based study

scientific article

Pain and quality of life in hospitalized patients with heart failure

scientific article published on 10 July 2008

Pain experiences of men and women after cardiac surgery

scientific article published on 15 June 2016

Pain sensitivity and analgesic use among 10,486 adults: the Tromsø study

scientific article

Paratracheal placement of orotracheal tube: a complication when aborting percutaneous tracheotomy

scientific article

Percutaneous dilatational tracheotomy in intensive care unit patients with increased bleeding risk or obesity. A prospective analysis of 1000 procedures

scientific article published on 25 May 2011

Persistent analgesic use and the association with chronic pain and other risk factors in the population-a longitudinal study from the Tromsø Study and the Norwegian Prescription Database

scientific article

Persistent pain after surgery for cutaneous melanoma

scientific article published in February 2012

Persistent post-surgical pain and experimental pain sensitivity in the Tromsø study: comorbid pain matters.

scientific article

Persistent post-surgical pain and signs of nerve injury: the Tromsø Study

scientific article

Persistent postsurgical pain in a general population: prevalence and predictors in the Tromsø study

scientific article published on 24 March 2012

Placebo control--still the most ethical study design

scientific article published on 03 December 2009

Postoperative urinary retention

scientific article published in April 2002

Predictable reduction of intracranial hypertension with hypertonic saline hydroxyethyl starch: a prospective clinical trial in critically ill patients with subarachnoid haemorrhage

scientific article published in October 2004

Pregabalin Has Analgesic, Ventilatory, and Cognitive Effects in Combination with Remifentanil

scientific article published on 3 November 2015

Pregabalin reduces opioid consumption and hyperalgesia but not pain intensity after laparoscopic donor nephrectomy

scientific article published on 28 August 2017

Preinjury treatment with morphine or ketamine inhibits the development of experimentally induced secondary hyperalgesia in man.

scientific article published in June 2000

Preoperative quantitative sensory testing (QST) predicting postoperative pain: Image or mirage?

scientific article published on 24 February 2017

Pressure-derived versus pressure wave amplitude–derived indices of cerebrovascular pressure reactivity in relation to early clinical state and 12-month outcome following aneurysmal subarachnoid hemorrhage ⬇️

scientific article published on February 10, 2012

Prevalence, Location, and Characteristics of Chronic Pain in Intensive Care Survivors

scientific article

Prostaglandin E2 production in synovial tissue and acute postoperative pain after knee arthroscopy

Randomized controlled trial of intra-articular ketorolac on pain and inflammation after minor arthroscopic knee surgery

scientific article published on 7 March 2018

Relief of Glossopharyngeal Neuralgia by Ketamine-induced /V-Methyl-aspartate Receptor Blockade ⬇️

scientific article published on August 1, 1997

Relief of Trigeminal Neuralgia after Percutaneous Retrogasserian Glycerol Rhizolysis Is Dependent on Normalization of Abnormal Temporal Summation of Pain, without General Impairment of Sensory Perception ⬇️

scientific article published on September 1, 1998

Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo

scientific article

Reply to S.T. Meller: Ketamine: relief from chronic pain through actions at the NMDA receptor

scientific article published in August 1997

Response to the Letter to the Editor: Experimental Comparison of Parametric Versus Nonparametric Analyses of Data From the Cold Pressor Test

scientific article published in January 2016

Sensory Perception in Patients with Trigeminal Neuralgia: Effects of Percutaneous Retrogasserian Glycerol Rhizotomy ⬇️

scientific article published on January 1, 1997

Skin pain and discomfort in psoriasis: an exploratory study of symptom prevalence and characteristics

scientific article published in January 2010

Skin pain and skin discomfort is associated with quality of life in patients with psoriasis ⬇️

scientific article published on March 8, 2011

Sleep and pain sensitivity in adults

scientific article published on August 2015

Statistical pearls: Importance of effect-size, blinding, randomization, publication bias, and the overestimated p-values

article

Surgical treatment of aneurysmal subarachnoid haemorrhage in the presence of 24-h endovascular availability: management and results

scientific article published in February 2008

The effect of peripheral glycerol on trigeminal neuropathic pain examined by quantitative assessment of abnormal pain and sensory perception

scientific article

The effect of tracheotomy on drug consumption in patients with acute aneurysmal subarachnoid hemorrhage: an observational study

scientific article

The impact of an educational pain management booklet intervention on postoperative pain control after cardiac surgery

scientific article published on 4 February 2016

The incidence of delirium in Norwegian intensive care units; deep sedation makes assessment difficult ⬇️

scientific article published on October 17, 2012

Ultrasound controlled nerve stimulation in the elbow region: high currents and short distances needed to obtain motor responses

scientific article

Use of magnetic resonance imaging to define the anatomical location closest to all three cords of the infraclavicular brachial plexus

scientific article published in December 2006

Validation of the Norwegian Pain Sensitivity Questionnaire

scientific article

Why are some patients with chronic pain from anterior abdominal nerve entrapment syndrome (ACNES) refractory to peripheral treatment with neurectomy?

scientific article published on 16 December 2016

Why we publish negative studies – and prescriptions on how to do clinical pain trials well

Widespread hyperalgesia in adolescents with symptoms of irritable bowel syndrome: results from a large population-based study

scientific article published on 4 June 2014

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