List of works by Marie-Cécile Le Deley

A Pharmacokinetic and Pharmacogenetic Analysis of Osteosarcoma Patients Treated With High-Dose Methotrexate: Data From the OS2006/Sarcoma-09 Trial

scientific article published on 23 May 2018

A double-blind placebo-controlled randomized phase II trial assessing the activity and safety of regorafenib in non-adipocytic sarcoma patients previously treated with both chemotherapy and pazopanib

scientific article published on 06 January 2020

A new approach to integrate toxicity grade and repeated treatment cycles in the analysis and reporting of phase I dose-finding trials.

scientific article published on 17 November 2014

Anthracyclines, mitoxantrone, radiotherapy, and granulocyte colony-stimulating factor: risk factors for leukemia and myelodysplastic syndrome after breast cancer.

scientific article published on 11 December 2006

Bayesian survival analysis in clinical trials: What methods are used in practice?

scientific article

Can postoperative radiotherapy be omitted in localised standard-risk Ewing sarcoma? An observational study of the Euro-E.W.I.N.G group

scientific article published on 10 May 2016

Central nervous system involvement in anaplastic large cell lymphoma in childhood: results from a multicentre European and Japanese study

scientific article published on 29 May 2013

Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite

scientific article

Circulating Cell-Free Tumor DNA Analysis of 50 Genes by Next-Generation Sequencing in the Prospective MOSCATO Trial

scientific article published on 12 January 2016

Clinical analysis and prognostic significance of haemophagocytic lymphohistiocytosis-associated anaplastic large cell lymphoma in children.

scientific article published on 21 January 2014

Concomitant chemo-radiotherapy and local dose of radiation as risk factors for second malignant neoplasms after solid cancer in childhood: a case-control study

scientific article published on January 2007

Cyclophosphamide compared with ifosfamide in consolidation treatment of standard-risk Ewing sarcoma: results of the randomized noninferiority Euro-EWING99-R1 trial

scientific article

Dose-finding approach for dose escalation with overdose control considering incomplete observations

scientific article published on 24 February 2011

Dose-finding designs using a novel quasi-continuous endpoint for multiple toxicities

scientific article published on 21 January 2013

EPT-01DOSE-FINDING STUDY OF VINBLASTINE IN COMBINATION WITH NILOTINIB IN CHILDREN, ADOLESCENTS AND YOUNG ADULTS WITH REFRACTORY OR RECURRENT LOW-GRADE GLIOMA: RESULTS OF THE ITCC/SIOPE-BRAIN VINILO PHASE I TRIAL (NCT01887522).

scientific article published on 30 May 2016

Effect of a misspecification of response rates on type I and type II errors, in a phase II Simon design.

scientific article published on 13 April 2011

Efficacy and safety of regorafenib compared to placebo and to post-cross-over regorafenib in advanced non-adipocytic soft tissue sarcoma

Equal access to innovative therapies and precision cancer care

scientific article published on 22 March 2016

Factors associated with success of image-guided tumour biopsies: Results from a prospective molecular triage study (MOSCATO-01).

scientific article published on 24 March 2016

Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations

scientific article

Hematopoietic stem cell transplantation in relapsed ALK+ anaplastic large cell lymphoma in children and adolescents: a study on behalf of the SFCE and SFGM-TC.

scientific article published on 30 March 2015

High cumulative rate of secondary leukemia after continuous etoposide treatment for solid tumors in children and young adults

scientific article published in July 2005

High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial

scientific article published on 01 April 2017

Identification of single nucleotide polymorphisms of the PI3K-AKT-mTOR pathway as a risk factor of central nervous system metastasis in metastatic breast cancer

scientific article published on 2 November 2017

Impact of early palliative care on overall survival of patients with metastatic upper gastrointestinal cancers treated with first-line chemotherapy: a randomised phase III trial

scientific article published on 23 January 2018

Impact of gender on efficacy and acute toxicity of alkylating agent -based chemotherapy in Ewing sarcoma: secondary analysis of the Euro-Ewing99-R1 trial

scientific article published on 10 August 2015

Impact of the methotrexate administration dose on the need for intrathecal treatment in children and adolescents with anaplastic large-cell lymphoma: results of a randomized trial of the EICNHL Group

scientific article published on 12 January 2009

Innovative Therapies for Children with Cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors

scientific article

Investigating the heterogeneity of alkylating agents' efficacy and toxicity between sexes: A systematic review and meta-analysis of randomized trials comparing cyclophosphamide and ifosfamide (MAIAGE study).

scientific article published on 23 January 2017

Limited stage I disease is not necessarily indicative of an excellent prognosis in childhood anaplastic large cell lymphoma.

scientific article published on 28 March 2011

Long-term results of the combination of the N7 induction chemotherapy and the busulfan-melphalan high dose chemotherapy

scientific article published on 23 August 2013

Multicenter randomized trial of chewing gum for preventing oral mucositis in children receiving chemotherapy

scientific article published on 01 February 2007

Neuro-meningeal relapse in anaplastic large-cell lymphoma: incidence, risk factors and prognosis - a report from the European intergroup for childhood non-Hodgkin lymphoma

scientific article published on 09 July 2020

New drugs for children and adolescents with cancer: the need for novel development pathways.

scientific article published on 20 February 2013

New insights into the evaluation of randomized controlled trials for rare diseases over a long-term research horizon: a simulation study

scientific article

Non-Hodgkin Lymphoma in Children and Adolescents: Progress Through Effective Collaboration, Current Knowledge, and Challenges Ahead

scientific article

Once weekly paclitaxel associated with a fixed dose of oral metronomic cyclophosphamide: a dose-finding phase 1 trial

scientific article published on 31 July 2018

Operating characteristics of two independent sample design in phase I trials in paediatric oncology.

scientific article published on 20 February 2010

Paediatric anaplastic large cell lymphoma with leukaemic presentation in children: a report of nine French cases

scientific article published on 14 February 2014

Phase I study of temsirolimus in combination with cetuximab in patients with advanced solid tumours.

scientific article published on 12 June 2017

Phase I study of topotecan in combination with temozolomide (TOTEM) in relapsed or refractory paediatric solid tumours

scientific article

Phase I trial of bortezomib daily dose: safety, pharmacokinetic profile, biological effects and early clinical evaluation in patients with advanced solid tumors.

scientific article published on 2 November 2017

Phase II study of temozolomide in combination with topotecan (TOTEM) in relapsed or refractory neuroblastoma: a European Innovative Therapies for Children with Cancer-SIOP-European Neuroblastoma study.

scientific article

Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma.

scientific article published on 7 February 2018

Phase-II trials in osteosarcoma recurrences: A systematic review of past experience

scientific article

Population analysis of erlotinib in adults and children reveals pharmacokinetic characteristics as the main factor explaining tolerance particularities in children.

scientific article published on 8 June 2011

Postoperative chemotherapy without irradiation for ependymoma in children under 5 years of age: a multicenter trial of the French Society of Pediatric Oncology.

scientific article

Postoperative radiotherapy in the management of adult soft tissue sarcoma of the extremities: results with two different total dose, fractionation, and overall treatment time schedules

scientific article published on 01 July 1999

Prediction of fluid responsiveness by a continuous non-invasive assessment of arterial pressure in critically ill patients: comparison with four other dynamic indices

scientific article published on 26 June 2012

Primary cutaneous and subcutaneous Ewing sarcoma.

scientific article published on 20 April 2015

Primary disseminated multifocal Ewing sarcoma: results of the Euro-EWING 99 trial.

scientific article published on 14 June 2010

Prognostic and predictive factors for angiosarcoma patients receiving paclitaxel once weekly plus or minus bevacizumab: an ancillary study derived from a randomized clinical trial

scientific article published on 11 October 2018

Prognostic factors in childhood anaplastic large cell lymphoma: results of a large European intergroup study

scientific article

Prognostic impact of morphologic and phenotypic features of childhood ALK-positive anaplastic large-cell lymphoma: results of the ALCL99 study

scientific article published on 14 November 2011

Prognostic value of circulating VEGFR2+ bone marrow-derived progenitor cells in patients with advanced cancer

scientific article published on 25 February 2012

Progression-free survival in children with optic pathway tumors: dependence on age and the quality of the response to chemotherapy--results of the first French prospective study for the French Society of Pediatric Oncology

scientific article published in December 2003

Pure and mixed fibrolamellar hepatocellular carcinomas differ in natural history and prognosis after complete surgical resection

scientific article published on 13 March 2012

RECIST response and variation of circulating tumour cells in phase 1 trials: A prospective multicentric study

scientific article published on 22 July 2017

Relapses of childhood anaplastic large-cell lymphoma: Treatment results in a series of 41 children - a report from the French Society of Pediatric Oncology

article

Relationship between the brain radiation dose for the treatment of childhood cancer and the risk of long-term cerebrovascular mortality

scientific article published on 01 May 2011

Results of API-AI based regimen in osteosarcoma adult patients included in the French OS2006/Sarcome-09 study

scientific article published on 19 July 2019

Results of a multicenter phase I dose-finding trial of hyperthermic intraperitoneal cisplatin after neoadjuvant chemotherapy and complete cytoreductive surgery and followed by maintenance bevacizumab in initially unresectable ovarian cancer.

scientific article

Results of methotrexate-etoposide-ifosfamide based regimen (M-EI) in osteosarcoma patients included in the French OS2006/sarcome-09 study.

scientific article

Risk of Subsequent Leukemia After a Solid Tumor in Childhood: Impact of Bone Marrow Radiation Therapy and Chemotherapy

scientific article

Risk of secondary leukemia after a solid tumor in childhood according to the dose of epipodophyllotoxins and anthracyclines: a case-control study by the Société Française d'Oncologie Pédiatrique.

scientific article published in March 2003

Role of radiation dose in the risk of secondary leukemia after a solid tumor in childhood treated between 1980 and 1999.

scientific article published on 19 March 2010

Role of radiotherapy and chemotherapy in the risk of secondary leukaemia after a solid tumour in childhood

scientific article published on 11 September 2006

SAE: an R package for early stopping rules in clinical trials

scientific article published on 07 July 2011

SFOP OS94: a randomised trial comparing preoperative high-dose methotrexate plus doxorubicin to high-dose methotrexate plus etoposide and ifosfamide in osteosarcoma patients

scientific article published on 30 January 2007

Safety assessment of intensive induction therapy in childhood anaplastic large cell lymphoma: Report of the ALCL99 randomised trial

scientific article published on 28 January 2011

Taking the long view: how to design a series of Phase III trials to maximize cumulative therapeutic benefit

scientific article published on 08 May 2012

Target-driven exploratory study of imatinib mesylate in children with solid malignancies by the Innovative Therapies for Children with Cancer (ITCC) European Consortium.

scientific article

Treatment of medulloblastoma with postoperative chemotherapy alone: an SFOP prospective trial in young children.

scientific article published in August 2005

Variations in the breast reconstruction rate in France: A nationwide study of 19,466 patients based on the French medico-administrative database

scientific article published on 06 August 2018

Vinblastine in children and adolescents with high-risk anaplastic large-cell lymphoma: results of the randomized ALCL99-vinblastine trial.

scientific article published on 2 August 2010

Zoledronate in combination with chemotherapy and surgery to treat osteosarcoma (OS2006): a randomised, multicentre, open-label, phase 3 trial

scientific article published on 17 June 2016

[Neoadjuvant treatment in osteosarcomas]

scientific article published on 01 November 2006

[Parents' opinions of pediatric oncology day hospitals]

scientific article published on 01 August 2000

[The role of the expansion cohort in phase I trials in oncology: guidelines of the phase I HUB]

scientific article published on 02 January 2015

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