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List of works by Rachel Nechushtai

A point mutation in the [2Fe–2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties

scientific article

Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells

scientific article published on 30 November 2015

Allosteric control in a metalloprotein dramatically alters function ⬇️

scientific article published on December 27, 2012

Allostery in the ferredoxin protein motif does not involve a conformational switch

scientific article

Binding of histidine in the (Cys)3(His)1-coordinated [2Fe-2S] cluster of human mitoNEET.

scientific article

Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters

scientific article published on 12 September 2016

Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis

scientific article published on 8 October 2015

Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2

scientific article

Discovering Novel and Diverse Iron-Chelators in Silico

scientific article published on December 2016

Engineering the Redox Potential over a Wide Range within a New Class of FeS Proteins ⬇️

scientific article published on September 29, 2010

Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein

scientific article

GLP-1-RA Corrects Mitochondrial Labile Iron Accumulation and Improves β-Cell Function in Type 2 Wolfram Syndrome

scientific article published on 26 July 2016

Generation of photocurrents by bis-aniline-cross-linked Pt nanoparticle/photosystem I composites on electrodes

scientific article published on 22 April 2010

Integrated photosystem II-based photo-bioelectrochemical cells ⬇️

scientific article published on March 13, 2012

Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1.

scientific article published on 25 March 2014

Interactions between mitoNEET and NAF-1 in cells

scientific article

MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone

scientific article

Molecular Dynamics Simulations of the [2Fe-2S] Cluster-Binding Domain of NEET Proteins Reveal Key Molecular Determinants That Induce Their Cluster Transfer/Release

scientific article published on 31 October 2017

Mutation of the His ligand in mitoNEET stabilizes the 2Fe–2S cluster despite conformational heterogeneity in the ligand environment

scientific article

NADPH Inhibits [2Fe-2S] Cluster Protein Transfer from Diabetes Drug Target MitoNEET to an Apo-acceptor Protein ⬇️

scientific article published on February 17, 2012

NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth

scientific article published on 19 August 2013

Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs

scientific article

Photosynthetic reaction center-functionalized electrodes for photo-bioelectrochemical cells ⬇️

scientific article published on February 1, 2013

Photosystem I (PSI)/Photosystem II (PSII)-based photo-bioelectrochemical cells revealing directional generation of photocurrents

scientific article published on 18 April 2013

Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates

scientific article published on 16 February 2017

Purification, crystallization and preliminary X-ray analysis of ferredoxin isolated from thermophilic cyanobacterium Mastigocladus laminosus

scientific article published on 25 March 2003

Resonance Raman studies of the (His)(Cys)3 2Fe-2S cluster of MitoNEET: comparison to the (Cys)4 mutant and implications of the effects of pH on the labile metal center

scientific article

Structural basis for the thermostability of ferredoxin from the cyanobacterium Mastigocladus laminosus

scientific article published in July 2005

Structure-function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease

scientific article

The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer

scientific article

The novel 2Fe–2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain

scientific article

The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster

scientific article published on 21 June 2007

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