List of works - Marc Schmidt-Supprian

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response

scientific article

A novel Cre recombinase reporter mouse strain facilitates selective and efficient infection of primary immune cells with adenoviral vectors

scientific article published on 17 April 2015

A20-deficient mast cells exacerbate inflammatory responses in vivo

scientific article published on 14 January 2014

Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice

scientific article

Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells

scientific article

An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression

scientific article published on 23 April 2015

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice

scientific journal article

BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells

scholarly article

Brain endothelial TAK1 and NEMO safeguard the neurovascular unit

scientific article

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells

scientific article published on 20 April 2016

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation

scientific article

Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice

scientific article

Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma

scientific article

Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals

scientific article published on 03 May 2009

Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation

scholarly article

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis

scientific article

GP130 activation induces myeloma and collaborates with MYC.

scientific article published on 10 November 2014

Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis

scholarly article

IkappaB kinase signaling is essential for maintenance of mature B cells

scientific journal article

K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

scientific article

Loss of Roquin induces early death and immune deregulation but not autoimmunity

scientific journal article

Machine Learning-based Classification of Diffuse Large B-cell Lymphoma Patients by Their Protein Expression Profiles

scientific article

N-linked glycosylation enrichment for in-depth cell surface proteomics of diffuse large B-cell lymphoma subtypes

scientific article

NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation

scientific article

NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells

scholarly article

NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses

scientific article

NIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysis

scientific article

NKT cell-TCR expression activates conventional T cells in vivo, but is largely dispensable for mature NKT cell biology

scientific article (publication date: 2013)

Persistent inflammation leads to proliferative neoplasia and loss of smooth muscle cells in a prostate tumor model

scientific article

Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase

scientific article published on October 2011

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway

scientific article published on 14 July 2015

Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation

scientific journal article

Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program

scientific article

Studying Epstein-Barr virus pathologies and immune surveillance by reconstructing EBV infection in mice

scientific article published on 15 November 2013

Super-SILAC allows classification of diffuse large B-cell lymphoma subtypes by their protein expression profiles

scientific article

TCR signals fuel Treg cells

scientific article published on 12 July 2015

Tissue-specific tumorigenesis: context matters

scientific article

Vagaries of conditional gene targeting

scientific article published on July 2007

Yin Yang 1 is a critical regulator of B-cell development

scientific article published on May 2007

γ-Secretase directly sheds the survival receptor BCMA from plasma cells

scientific article published on 11 June 2015

List of works by Marc Schmidt-Supprian

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response

A novel Cre recombinase reporter mouse strain facilitates selective and efficient infection of primary immune cells with adenoviral vectors

A20-deficient mast cells exacerbate inflammatory responses in vivo

Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice

Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells

An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice

BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells

Brain endothelial TAK1 and NEMO safeguard the neurovascular unit

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation

Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice

Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma

Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals

Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis

GP130 activation induces myeloma and collaborates with MYC.

Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis

IkappaB kinase signaling is essential for maintenance of mature B cells

K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

Loss of Roquin induces early death and immune deregulation but not autoimmunity

Machine Learning-based Classification of Diffuse Large B-cell Lymphoma Patients by Their Protein Expression Profiles

N-linked glycosylation enrichment for in-depth cell surface proteomics of diffuse large B-cell lymphoma subtypes

NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation

NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells

NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses

NIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysis

NKT cell-TCR expression activates conventional T cells in vivo, but is largely dispensable for mature NKT cell biology

Persistent inflammation leads to proliferative neoplasia and loss of smooth muscle cells in a prostate tumor model

Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway

Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation

Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program

Studying Epstein-Barr virus pathologies and immune surveillance by reconstructing EBV infection in mice

Super-SILAC allows classification of diffuse large B-cell lymphoma subtypes by their protein expression profiles

TCR signals fuel Treg cells

Tissue-specific tumorigenesis: context matters

Vagaries of conditional gene targeting

Yin Yang 1 is a critical regulator of B-cell development

γ-Secretase directly sheds the survival receptor BCMA from plasma cells