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List of works by Simona Di Giambenedetto

A Prognostic Model for Estimating the Time to Virologic Failure in HIV-1 Infected Patients Undergoing a New Combination Antiretroviral Therapy Regimen ⬇️

scientific article published on June 14, 2011

A comparison between abacavir and efavirenz as the third drug used in combination with a background therapy regimen of 2 nucleoside reverse-transcriptase inhibitors in patients with initially suppressed viral loads

scientific article published on 16 May 2006

A novel methodology for large-scale phylogeny partition

scientific article published on 24 May 2011

A randomized controlled trial to evaluate antiretroviral salvage therapy guided by rules-based or phenotype-driven HIV-1 genotypic drug-resistance interpretation with or without concentration-controlled intervention: the Resistance and Dosage Adapte

scientific article published on 12 May 2005

Adherence and plasma drug concentrations are predictors of confirmed virologic response after 24-week salvage highly active antiretroviral therapy

scientific article

Antiretroviral neuropenetration scores better correlate with cognitive performance of HIV-infected patients after accounting for drug susceptibility

scientific article published on 17 December 2014

Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models

scientific article

Are mutations in HIV type-1 reverse transcriptase 245 codon predictive of abacavir hypersensitivity reaction?

scientific article published in January 2009

Association of HIV-1 replication capacity with treatment outcomes in patients with virologic treatment failure

scientific article published on 01 August 2007

Asymmetry of the regimen is correlated to self-reported suboptimal adherence: results from AdUCSC, a cohort study on adherence in Italy

scientific article published in November 2010

Atazanavir/ritonavir monotherapy as maintenance strategy in HIV-1 treated subjects with viral suppression: 96-week analysis results of the MODAT study

scientific article

Atazanavir/ritonavir monotherapy: 96 week efficacy, safety and bone mineral density from the MODAt randomized trial

scientific article published on 5 March 2016

Baseline CD4(+) T-cell count and cardiovascular risk factors predict the evolution of cognitive performance during 2-year follow-up in HIV-infected patients

scientific article published on 11 December 2014

Budget impact analysis of the simplification to atazanavir + ritonavir + lamivudine dual therapy of HIV-positive patients receiving atazanavir-based triple therapies in Italy starting from data of the Atlas-M trial

scientific article

CD4 cell-monitored treatment interruption in patients with a CD4 cell count > 500 x 106 cells/l.

scientific article published on February 2005

Characterization of JC virus in cerebrospinal fluid from HIV-1 infected patients with progressive multifocal leukoencephalopathy: insights into viral pathogenesis and disease prognosis

scientific article published in August 2007

Cidofovir in addition to antiretroviral treatment is not effective for AIDS-associated progressive multifocal leukoencephalopathy: a multicohort analysis

scientific article published in September 2008

Coccidioidomycosis of cervical lymph nodes in an HIV-infected patient with immunologic reconstitution on potent HAART: a rare observation in a nonendemic area ⬇️

scientific article published on November 21, 2011

Cognitive reserve and neuropsychological functioning in older HIV-infected people.

scientific article published on 10 March 2016

Combining social and genetic networks to study HIV transmission in mixing risk groups

article

Comparative determination of HIV-1 co-receptor tropism by Enhanced Sensitivity Trofile, gp120 V3-loop RNA and DNA genotyping

scientific article

Construction, training and clinical validation of an interpretation system for genotypic HIV-1 drug resistance based on fuzzy rules revised by virological outcomes.

scientific article published in August 2004

Cross-resistance among nonnucleoside reverse transcriptase inhibitors limits recycling efavirenz after nevirapine failure

scientific article published in August 2002

Darunavir/ritonavir and raltegravir coadministered in routine clinical practice: Potential role for an unexpected drug interaction

scientific article published on 02 December 2010

Declining Prevalence of HIV-1 Drug Resistance in Antiretroviral Treatment-exposed Individuals in Western Europe ⬇️

scientific article published on January 11, 2013

Declining prevalence of HIV-1 drug resistance in treatment-failing patients: a clinical cohort study

scientific article published on January 2007

Deep salvage with amprenavir and lopinavir/ritonavir: correlation of pharmacokinetics and drug resistance with pharmacodynamics.

scientific article published in April 2004

Detection of HLA-B*57:01 by real-time PCR: implementation into routine clinical practice and additional validation data

scientific article

Detection of drug resistance mutations at low plasma HIV-1 RNA load in a European multicentre cohort study ⬇️

scientific article published on May 30, 2011

Determination of Phenotypic Resistance Cutoffs From Routine Clinical Data

scientific article

Dolutegravir Plus Rilpivirine as a Switch Option in cART-Experienced Patients: 96-Week Data.

scientific article

Drug-resistant mutants of HIV-1 in patients exhibiting increasing CD4 cell count despite virological failure of highly active antiretroviral therapy.

scientific article

Effect of aging and human immunodeficiency virus infection on cognitive abilities

scientific article published on 30 October 2012

Efficacy and tolerability of dolutegravir and two nucleos(t)ide reverse transcriptase inhibitors in HIV-1-positive, virologically suppressed patients

scientific article

Efficacy and tolerability of lamivudine plus dolutegravir compared with lamivudine plus boosted PIs in HIV-1 positive individuals with virologic suppression: a retrospective study from the clinical practice

article

Efficacy and tolerability of switching to a dual therapy with darunavir/ritonavir plus raltegravir in HIV-infected patients with HIV-1 RNA ≤50 cp/mL.

scientific article published on 5 May 2017

Erratum: Budget impact analysis of the simplification to atazanavir + ritonavir + lamivudine dual therapy of HIV-positive patients receiving atazanavir-based triple therapies in Italy starting from data of the Atlas-M trial [Corrigendum]

article

Evaluation and Optimization of an ELISA Procedure to Quantify Antibodies Against Pneumococcal Polysaccharides Included in the 13-Valent Conjugate Vaccine.

scientific article published on 27 October 2015

Evaluation of emotion processing in HIV-infected patients and correlation with cognitive performance.

scientific article

Evolution and predictors of HIV type-1 drug resistance in patients failing combination antiretroviral therapy in Italy

scientific article published on January 2009

Evolution of blood-associated HIV-1 DNA levels after 48 weeks of switching to atazanavir/ritonavir+lamivudine dual therapy versus continuing triple therapy in the randomized AtLaS-M trial

scientific article

Exploratory Analysis for the Evaluation of Estimated Glomerular Filtration Rate, Cholesterol and Triglycerides after Switching from Tenofovir/Emtricitabine plus Atazanavir/Ritonavir (ATV/r) to Abacavir/Lamivudine plus ATV/r in Patients with Preserve

scientific article published on 15 July 2016

Female sex and the use of anti-allergic agents increase the risk of developing cutaneous rash associated with nevirapine therapy

scientific article

Frequency and Treatment‐Related Predictors of Thymidine‐Analogue Mutation Patterns in HIV‐1 Isolates after Unsuccessful Antiretroviral Therapy

article

Genotypic resistance to lopinavir and fosamprenavir with or without ritonavir of clinical isolates from patients failing protease inhibitors-containing HAART regimens: prevalence and predictors

scientific article published in January 2007

HIV tropism and its relationship with transmitted resistance in naive patients

article

HIV-infected patients show impaired cellular immune response to influenza vaccination compared to healthy subjects

scientific article published on 24 April 2013

Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients

article

Immunogenicity and Safety of the 13-Valent Pneumococcal Conjugate Vaccine versus the 23-Valent Polysaccharide Vaccine in Unvaccinated HIV-Infected Adults: A Pilot, Prospective Controlled Study

scientific article

Impact of 48 weeks of atazanavir/ritonavir plus lamivudine dual therapy on cellular HIV-DNA levels in the AtLaS pilot study

scientific article published on 3 August 2016

Impact of the M184V Resistance Mutation on Virological Efficacy and Durability of Lamivudine-Based Dual Antiretroviral Regimens as Maintenance Therapy in Individuals With Suppressed HIV-1 RNA: A Cohort Study.

scientific article

Improved interpretation of genotypic changes in the HIV-1 reverse transcriptase coding region that determine the virological response to didanosine

scientific article published on 26 October 2007

Increased ophthalmic artery resistance index is associated with cognitive impairment in HIV-infected patients.

scientific article published on 3 August 2012

Influence of viral chronic hepatitis co-infection on plasma drug concentrations and liver transaminase elevations upon therapy switch in HIV-positive patients

scientific article published on 2 October 2006

Interpretation of genotypic HIV-1 resistance to darunavir and virological response: validation of available systems and of a new score

scientific article

Is There a Drug–Drug Interaction Between Darunavir/Ritonavir and Raltegravir?

scientific article published on 01 May 2012

Is the virulence of HIV changing? A meta-analysis of trends in prognostic markers of HIV disease progression and transmission

scientific article

Late presenters in new HIV diagnoses from an Italian cohort of HIV-infected patients: prevalence and clinical outcome

scientific article published on January 2011

Lipid abnormalities in HIV-infected patients are not correlated with lopinavir plasma concentrations

scientific article published in March 2004

Lipid-lowering effect and changes in estimated cardiovascular risk after switching to a tenofovir-containing regimen for the treatment of HIV-infected patients

scientific article published on 26 December 2016

Lipid-lowering effect of tenofovir in HIV-infected patients

article

Liver fibrosis is associated with cognitive impairment in HIV-positive patients

scientific article published on 2 November 2014

Liver fibrosis progression and clinical outcomes are intertwined: role of CD4+ T-cell count and NRTI exposure from a large cohort of HIV/HCV-coinfected patients with detectable HCV-RNA: A MASTER cohort study

scientific article published on July 2016

Liver fibrosis stage predicts early treatment outcomes with peginterferon plus ribavirin in HIV/hepatitis C virus co-infected patients

scientific article published in July 2004

Local Epidemics Gone Viral: Evolution and Diffusion of the Italian HIV-1 Recombinant Form CRF60_BC

article

Longitudinal analysis of HIV-1 coreceptor tropism by single and triplicate HIV-1 RNA and DNA sequencing in patients undergoing successful first-line antiretroviral therapy

scientific article published on 23 October 2013

Low rate of virological failure and maintenance of susceptibility to HIV‐1 protease inhibitors with first‐line lopinavir/ritonavir‐based antiretroviral treatment in clinical practice ⬇️

scientific article published on December 1, 2010

Macrophage chemoattractant protein-1 levels in cerebrospinal fluid correlate with containment of JC virus and prognosis of acquired immunodeficiency syndrome--associated progressive multifocal leukoencephalopathy

scientific article

Mitochondrial DNA Haplogroups and Incidence of Lipodystrophy in HIV-Infected Patients on Long-Term Antiretroviral Therapy

article

Mitochondrial DNA haplogroups and incidence of lipodystrophy in HIV-infected patients on long-term antiretroviral therapy

article

Mortality in patients with early- or late-onset candidaemia

scientific article published on 12 December 2012

Naturally occurring hepatitis C virus (HCV) NS3/4A protease inhibitor resistance-related mutations in HCV genotype 1-infected subjects in Italy

scientific article published on 18 January 2012

Neuropsychological screening tools in Italian HIV+ patients: a comparison of Montreal Cognitive Assessment (MoCA) and Mini Mental State Examination (MMSE).

scientific article published on 16 May 2016

No pol mutation is associated independently with the lack of immune recovery in patients infected with HIV and failing antiretroviral therapy

scientific article published on March 2011

Novel sensitive, specific and rapid pharmacogenomic test for the prediction of abacavir hypersensitivity reaction: HLA-B*57:01 detection by real-time PCR.

scientific article published in April 2011

Ophthalmic artery resistance index is increased in HIV-Infected patients and is influenced by protease inhibitors exposure

article

Pharmacokinetic variability of antiretroviral drugs and correlation with virological outcome: 2 years of experience in routine clinical practice

scientific article published on 27 April 2009

Predictors of first-line antiretroviral therapy discontinuation due to drug-related adverse events in HIV-infected patients: a retrospective cohort study

scientific article

Prevalence of osteoporosis and predictors of low BMD in a cohort of HIV-1-infected patients in Rome: features of a population at high risk

scientific article published on 2 November 2014

Prognostic Value of the Fibrosis-4 Index in Human Immunodeficiency Virus Type-1 Infected Patients Initiating Antiretroviral Therapy with or without Hepatitis C Virus

scientific article published on 7 December 2015

Prospective evaluation of epidemiological, clinical, and microbiological features of pandemic influenza A (H1N1) virus infection in Italy

scientific article

Reduced rate of diagnostic positive detection of JC virus DNA in cerebrospinal fluid in cases of suspected progressive multifocal leukoencephalopathy in the era of potent antiretroviral therapy

scientific article

Reduced soluble CD14 levels after switching from a dual regimen with lamivudine plus boosted protease inhibitors to lamivudine plus dolutegravir in virologically suppressed HIV-infected patients

scientific article published on 03 September 2019

Relationship between self-reported adherence, antiretroviral drug concentration measurement and self-reported symptoms in patients treated for HIV-1 infection.

scientific article published on 2 September 2015

Revised central nervous system neuropenetration-effectiveness score is associated with cognitive disorders in HIV-infected patients with controlled plasma viraemia

scientific article published on 13 March 2013

Risk of Liver Enzyme Elevation During Treatment With Ritonavir-Boosted Protease Inhibitors Among HIV-Monoinfected and HIV/HCV-Coinfected Patients

scientific article published on 26 February 2015

Risk of Severe Non AIDS Events Is Increased among Patients Unable to Increase their CD4+ T-Cell Counts >200+/μl Despite Effective HAART

scientific article published on 28 May 2015

Rules-based HIV-1 genotypic resistance interpretation systems predict 8 week and 24 week virological antiretroviral treatment outcome and benefit from drug potency weighting

article

Safety and efficacy of treatment switch to raltegravir plus tenofovir/emtricitabine or abacavir/lamivudine in patients with optimal virological control: 48-week results from a randomized pilot study (Raltegravir Switch for Toxicity or Adverse Events

scientific article published on 28 October 2013

Safety and feasibility of treatment simplification to atazanavir/ritonavir + lamivudine in HIV-infected patients on stable treatment with two nucleos(t)ide reverse transcriptase inhibitors + atazanavir/ritonavir with virological suppression (Atazana

scientific article published on 30 January 2013

Safety and therapeutic efficacy of the switch to maraviroc+darunavir/ritonavir in HIV/HCV coinfected patients: initial results from GUSTA study

scientific article published on 2 November 2014

Simplification to atazanavir/ritonavir+lamivudine in virologically suppressed HIV-infected patients: 24-weeks interim analysis from ATLAS-M trial

scientific article

Simplification to co-formulated rilpivirine/emtricitabine/tenofovir in virologically suppressed patients: Data from a multicenter cohort

scientific article

Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients

scientific article published on 13 January 2014

Switch to Dolutegravir plus Rilpivirine Dual Therapy in cART-Experienced Subjects: An Observational Cohort

scientific article

Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA.

scientific article published on 2 November 2014

Switching to Coformulated Rilpivirine/Emtricitabine/Tenofovir in Virologically Suppressed Patients: Data From a Multicenter Cohort

scientific article published on 18 June 2015

Switching to boosted protease inhibitor plus a second antiretroviral drug (dual therapy) for treatment simplification: a multicenter analysis

scientific article

Switching to boosted protease inhibitor plus a second antiretroviral drug (dual therapy) for treatment simplification: a multicenter observational study

scientific article

Switching to lamivudine plus darunavir/r dual therapy in a cohort of treatment-experienced HIV-positive patients: the experience of an Italian centre.

scientific article published on 2 November 2014

Tenofovir discontinuation could predispose to urolithiasis in atazanavir-treated patients

scientific article published on 15 February 2011

The effect of polymorphisms in candidate genes on the long-term risk of lipodystrophy and dyslipidemia in HIV-infected white patients starting antiretroviral therapy

scientific article published on 20 June 2011

The effect of primary drug resistance on CD4 cell decline and the viral load set-point in HIV positive individuals before the start of antiretroviral therapy

article

The effect of primary drug resistance on CD4+ cell decline and the viral load set-point in HIV-positive individuals before the start of antiretroviral therapy

article

The influence of hepatitis C virus coinfection on the risk of lipid abnormalities in a cohort of HIV-1-infected patients after initiation of highly active antiretroviral therapy

scientific article published in May 2004

The threshold bootstrap clustering: a new approach to find families or transmission clusters within molecular quasispecies

scientific article

Total cellular HIV-1 DNA decreases after switching to raltegravir-based regimens in patients with suppressed HIV-1 RNA.

scientific article published on 23 March 2017

Treatment simplification to atazanavir/ritonavir + lamivudine versus maintenance of atazanavir/ritonavir + two NRTIs in virologically suppressed HIV-1-infected patients: 48 week results from a randomized trial (ATLAS-M).

scientific article

Triple-nucleoside regimens versus efavirenz

scientific article

Two Distinct Hepatitis C Virus Genotype 1a Clades Have Different Geographical Distribution and Association With Natural Resistance to NS3 Protease Inhibitors

scientific article published on 31 March 2015

Update of the budget impact analysis of the simplification to atazanavir + ritonavir + lamivudine dual therapy of HIV-positive patients receiving atazanavir-based triple therapies in Italy starting from data of the Atlas-M trial

scientific article published on 27 September 2017

Usefulness of monitoring HIV drug resistance and adherence in individuals failing highly active antiretroviral therapy: a randomized study (ARGENTA).

scientific article published in February 2002

Using a database of HIV patients undergoing genotypic resistance test after HAART failure to understand the dynamics of M184V mutation.

scientific article published in February 2003

Validation of an UPLC-MS/MS method for quantitative analysis of raltegravir in human plasma samples

scientific article published in April 2013

Variability in the interpretation of transmitted genotypic HIV-1 drug resistance and prediction of virological outcomes of the initial HAART by distinct systems.

scientific article published in October 2004

Variable prediction of antiretroviral treatment outcome by different systems for interpreting genotypic human immunodeficiency virus type 1 drug resistance

scientific article published on 22 May 2003

Verbal list learning and memory profiles in HIV-infected adults, Alzheimer's disease, and Parkinson's disease: An evaluation of the "cortical hypothesis" of NeuroAIDS.

scientific article published on 13 June 2016

Virological effectiveness and CD4+ T-cell increase over early and late courses in HIV infected patients on antiretroviral therapy: focus on HCV and anchor class received

scientific article

Virological suppression reduces clinical progression in patients with multiclass-resistant HIV type 1.

scientific article published on March 2009

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