Search filters

List of works by Mercedes Armand-Ugón

5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile

scientific article published on 17 July 2008

A Combination of Molecular Dynamics and Docking Calculations to Explore the Binding Mode of ADS-J1, a Polyanionic Compound Endowed with Anti-HIV-1 Activity

article

A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs

scientific article

Anti-HIV activity and resistance profile of the CXC chemokine receptor 4 antagonist POL3026.

scientific article published on 8 January 2008

Anti-HIV-1 activity of enfuvirtide (T-20) by inhibition of bystander cell death.

scientific article published in April 2003

Anti-human immunodeficiency virus type 1 (HIV-1) activity of lectins from Narcissus species.

scientific article published on February 2003

CLCN1 myotonia congenita mutation with a variable pattern of inheritance suggests a novel mechanism of dominant myotonia

scientific article published on 9 February 2018

Cell-Surface-Expressed HIV-1 Envelope Induces the Death of CD4 T Cells during GP41-Mediated Hemifusion-like Events

scientific article published on 01 January 2003

Depolarization causes the formation of a ternary complex between GlialCAM, MLC1 and ClC-2 in astrocytes: implications in megalencephalic leukoencephalopathy

scientific article published on 7 April 2017

Different selection patterns of resistance and cross-resistance to HIV-1 agents targeting CCR5.

scientific article

Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants.

scientific article

Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants

scientific article

Discovery of novel non-cyclam polynitrogenated CXCR4 coreceptor inhibitors

scientific article

Effect of polyanion-resistance on HIV-1 infection.

scientific article published on August 2004

Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G.

scientific article published on April 2000

GlialCAM/MLC1 modulates LRRC8/VRAC currents in an indirect manner: Implications for megalencephalic leukoencephalopathy

scientific article published on 01 August 2018

HIV-1 escape to CCR5 coreceptor antagonism through selection of CXCR4-using variants in vitro

scientific article published on January 2008

HIV-1 resistance to the anti-HIV activity of a shRNA targeting a dual-coding region

scientific article published on 18 December 2007

HIV-1 resistance to the gp41-dependent fusion inhibitor C-34.

scientific article

Inhibition of coreceptor-independent cell-to-cell human immunodeficiency virus type 1 transmission by a CD4-immunoglobulin G2 fusion protein

scientific article

Megalencephalic leukoencephalopathy with subcortical cysts: A personal biochemical retrospective.

scientific article published on 24 October 2017

Memory Improvement in the AβPP/PS1 Mouse Model of Familial Alzheimer’s Disease Induced by Carbamylated-Erythropoietin is Accompanied by Modulation of Synaptic Genes

scientific article published in January 2015

Multiparametric assay to screen and dissect the mode of action of anti-human immunodeficiency virus envelope drugs

scientific article

Neuroinflammatory Gene Regulation, Mitochondrial Function, Oxidative Stress, and Brain Lipid Modifications With Disease Progression in Tau P301S Transgenic Mice as a Model of Frontotemporal Lobar Degeneration-Tau

scientific article published on 10 September 2015

Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity

scientific article published on December 2005

Preferential attachment of HIV particles to activated and CD45RO+CD4+ T cells

scientific article published in January 2002

Reduced Mitochondrial Activity is Early and Steady in the Entorhinal Cortex but it is Mainly Unmodified in the Frontal Cortex in Alzheimer's Disease

scientific article published on 4 May 2017

Reduced fitness of HIV-1 resistant to CXCR4 antagonists

scientific article published on February 2003

Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants

scientific article published in September 2008

Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication

article

Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains

scientific article

The anti-HIV activity of ADS-J1 targets the HIV-1 gp120.

scientific article published on 15 September 2005

Towards novel S-DABOC inhibitors: synthesis, biological investigation, and molecular modeling studies

scientific article

Use of N-methylpiperazine for the preparation of piperazine-based unsymmetrical bis-ureas as anti-HIV agents.

scientific article

Paulina is supported by:

About Paulina

Help