List of works by Alessandro Cozzi-Lepri

A376S in the connection subdomain of HIV-1 reverse transcriptase confers increased risk of virological failure to nevirapine therapy.

scientific article

Access and response to direct antiviral agents (DAA) in HIV-HCV co-infected patients in Italy: Data from the Icona cohort

scientific article

Adherence to highly active antiretroviral therapy is better in patients receiving non-nucleoside reverse transcriptase inhibitor-containing regimens than in those receiving protease inhibitor-containing regimens

scientific article published in May 2003

An observational comparison of first-line combination antiretroviral treatment (cART) with 2NRTI and ATV/r or DRV/r in HIV-infected patients in Italy

scientific article published on 2 November 2014

Baseline resistance and virological outcome in patients with virological failure who start a regimen containing abacavir: EuroSIDA study

scientific article published in October 2004

CD4 cell count and the risk of infective and non-infective serious non-AIDS events in HIV-positive persons seen for care in Italy

scientific article

CD4 cell-monitored treatment interruption in patients with a CD4 cell count > 500 x 106 cells/l.

scientific article published on February 2005

CD4/CD8 ratio normalisation and non-AIDS-related events in individuals with HIV who achieve viral load suppression with antiretroviral therapy: an observational cohort study

scientific article published on 6 February 2015

Can linear regression modeling help clinicians in the interpretation of genotypic resistance data? An application to derive a lopinavir-score

scientific article

Co-administration of ritonavir-boosted protease inhibitors and rate of tenofovir discontinuation in clinical practice

scientific article

Coinfection with hepatitis viruses and outcome of initial antiretroviral regimens in previously naive HIV-infected subjects

scientific article published in October 2002

Common genetic variation and the control of HIV-1 in humans

scientific article published in December 2009

Comparison of genotypic resistance profiles and virological response between patients starting nevirapine and efavirenz in EuroSIDA.

scientific article

Computer-Aided Optimization of Combined Anti-Retroviral Therapy for HIV: New Drugs, New Drug Targets and Drug Resistance

scientific article

Cytomegalovirus coinfection is associated with an increased risk of severe non-AIDS-defining events in a large cohort of HIV-infected patients

scientific article published on 31 July 2014

Death rates in HIV-positive antiretroviral-naive patients with CD4 count greater than 350 cells per microL in Europe and North America: a pooled cohort observational study

scientific article

Detection of HIV drug resistance during antiretroviral treatment and clinical progression in a large European cohort study

article

Detection of resistance mutations and CD4 slopes in individuals experiencing sustained virological failure

scientific article published on 2 November 2014

Determinants of use of the fixed dose combination emtricitabine/rilpivirine/tenofovir (Eviplera) in HIV-infected persons receiving care in Italy

scientific article published on 2 November 2014

Development of a didanosine genotypic resistance interpretation system based on large derivation and validation datasets

scientific article published in January 2010

Discontinuation of Initial Antiretroviral Therapy in Clinical Practice: Moving Toward Individualized Therapy

scientific article published on March 2016

Drop in CD4+ counts below 200 cells/µL after reaching (or starting from) values higher than 350 cells/µL in HIV-infected patients with virological suppression

scientific article

Durability and tolerability of first-line regimens including two nucleoside reverse transcriptase inhibitors and raltegravir or ritonavir boosted-atazanavir or -darunavir: data from the ICONA Cohort

article by Antonella d'Arminio Monforte et al published April 2018 in HIV Clinical Trials

Durability of lopinavir/ritonavir dual-therapies in individuals with viral load <50 copies/mL in the observational setting

scientific article

Durability of lopinavir/ritonavir monotherapy in individuals with viral load ≤50 copies/ml in an observational setting

scientific article published on 13 September 2013

During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ

scientific article

Effect of hepatitis C virus genotype on CD4+ T cell count in a cohort of antiretroviral-naive HIV-1-infected individuals

scientific article published in August 2005

Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study

scientific article published on 25 February 2011

Effectiveness of dolutegravir-based regimens as either first-line or switch antiretroviral therapy: data from the Icona cohort

Efficacy and tolerability of switching to a dual therapy with darunavir/ritonavir plus raltegravir in HIV-infected patients with HIV-1 RNA ≤50 cp/mL.

scientific article published on 5 May 2017

Estimating prevalence of accumulated HIV-1 drug resistance in a cohort of patients on antiretroviral therapy

scientific article published on 31 January 2011

Evaluation of the Prognostic Value of Impaired Renal Function on Clinical Progression in a Large Cohort of HIV-Infected People Seen for Care in Italy

scientific article published on May 2015

Evolution of HVR-1 quasispecies after 1-year treatment in HIV/HCV-coinfected patients according to the pattern of response to highly active antiretroviral therapy

scientific article published in January 2006

Evolution of drug resistance in HIV-infected patients remaining on a virologically failing combination antiretroviral therapy regimen

scientific article published in March 2007

Evolution of major non-HIV-related comorbidities in HIV-infected patients in the Italian Cohort of Individuals, Naïve for Antiretrovirals (ICONA) Foundation Study cohort in the period 2004-2014

article

Evolution of the prevalence of HCV infection and HCV genotype distribution in HIV-infected patients in Italy between 1997 and 2015.

scientific article published on 29 July 2017

Exposure to abacavir and biomarkers of cardiovascular disease in HIV-1-infected patients on suppressive antiretroviral therapy: a longitudinal study

scientific article published in July 2012

Fosamprenavir/ritonavir in patients with viral hepatitis coinfection: an observational multicohort study

scientific article published on 16 March 2016

HIV resistance testing and detected drug resistance in Europe

scientific article published on July 2015

HIV-1 co-receptor tropism and liver fibrosis in HIV-infected patients

scientific article published on 11 January 2018

Immune activation and microbial translocation in liver disease progression in HIV/hepatitis co-infected patients: results from the Icona Foundation study

scientific article

Immuno-virological discordance and the risk of non-AIDS and AIDS events in a large observational cohort of HIV-patients in Europe

scientific article (publication date: 2014)

Impact of HIV-1 reverse transcriptase polymorphism F214L on virological response to thymidine analogue-based regimens in antiretroviral therapy (ART)-naive and ART-experienced patients

scientific article published on 19 September 2007

Impact of lamivudine on the risk of liver-related death in 2,041 HBsAg- and HIV-positive individuals: results from an inter-cohort analysis

scientific article

Impaired CD4 T-Cell Count Response to Combined Antiretroviral Therapy in Antiretroviral-Naive HIV-Infected Patients Presenting With Tuberculosis as AIDS-Defining Condition

scientific article published on 12 December 2011

Improved darunavir genotypic mutation score predicting treatment response for patients infected with HIV-1 subtype B and non-subtype B receiving a salvage regimen

scientific article published on 28 January 2016

Incidence and predictors of single drug discontinuation according to the presence of HCV coinfection in HIV patients from the ICONA Foundation Cohort Study

scientific article published on 9 January 2018

Incidence of adipose tissue alterations in first-line antiretroviral therapy: the LipoICoNa Study

scientific article published on December 2002

Increased incidence of sexually transmitted diseases in the recent years: data from the ICONA cohort

scientific article

Initiatives for developing and comparing genotype interpretation systems: external validation of existing systems for didanosine against virological response

scientific article published in August 2008

Invasive Candida infections and the harm from antibacterial drugs in critically ill patients: data from a randomized, controlled trial to determine the role of ciprofloxacin, piperacillin-tazobactam, meropenem, and cefuroxime

scientific article published on March 2015

Is the increased risk of liver enzyme elevation in patients co-infected with HIV and hepatitis virus greater in those taking antiretroviral therapy?

scientific article published on March 2007

Is there any potential for first-line etravirine use? Analysis from a large data set of antiretroviral therapy-naive HIV-infected patients undergoing resistance test

scientific article published in January 2010

Late presenters in new HIV diagnoses from an Italian cohort of HIV-infected patients: prevalence and clinical outcome

scientific article published on January 2011

Liver enzyme elevation during darunavir-based antiretroviral treatment in HIV-1-infected patients with or without hepatitis C coinfection: data from the ICONA foundation cohort

scientific article

Long term effectiveness of once-daily unboosted atazanavir plus abacavir/lamivudine as a switch strategy in subjects with virological suppression

scientific article

Long-Term Durability of Tenofovir-Based Antiretroviral Therapy in Relation to the Co-Administration of Other Drug Classes in Routine Clinical Practice

scientific article

Long-term effectiveness of unboosted atazanavir plus abacavir/lamivudine in subjects with virological suppression: A prospective cohort study

scientific article published on October 2016

Low prevalence of primary mutations associated with drug resistance in antiviral-naive patients at therapy initiation.

scientific article

Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART: a multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing

scientific article

Machine learning can identify newly diagnosed patients with CLL at high risk of infection

scientific article published on 17 January 2020

Mild induced hypothermia: effects on sepsis-related coagulopathy--results from a randomized controlled trial

scientific article

Minor mutations in HIV protease at baseline and appearance of primary mutation 90M in patients for whom their first protease-inhibitor antiretroviral regimens failed

scientific article

Mitochondrial DNA Haplogroups and Incidence of Lipodystrophy in HIV-Infected Patients on Long-Term Antiretroviral Therapy

article

Mitochondrial DNA haplogroups and incidence of lipodystrophy in HIV-infected patients on long-term antiretroviral therapy

article

Modelled in vivo HIV fitness under drug selective pressure and estimated genetic barrier towards resistance are predictive for virological response.

scientific article published in January 2008

Multiple viral infections

scientific article

Outcomes of influenza A(H1N1)pdm09 virus infection: results from two international cohort studies

scientific article

Plasma HIV-1 Tropism and the Risk of Short-Term Clinical Progression to AIDS or Death

scientific article

Plasma HIV-1 tropism and risk of short-term clinical progression to AIDS or death

scientific article

Plasma levels of cytokines and chemokines and the risk of mortality in HIV-infected individuals: a case-control analysis nested in a large clinical trial

scientific article published on April 2015

Predicting the magnitude of short-term CD4+ T-cell recovery in HIV-infected patients during first-line highly active antiretroviral therapy

scientific article published in January 2010

Predictors of having a resistance test following confirmed virological failure of combination antiretroviral therapy: data from EuroSIDA.

scientific article

Prevalence of Hypovitaminosis D and Factors Associated With Vitamin D Deficiency and Morbidity Among HIV-Infected Patients Enrolled in a Large Italian Cohort

article

Profound endothelial damage predicts impending organ failure and death in sepsis

scientific article published on 15 January 2015

Prognostic Value of the Fibrosis-4 Index in Human Immunodeficiency Virus Type-1 Infected Patients Initiating Antiretroviral Therapy with or without Hepatitis C Virus

scientific article published on 7 December 2015

Projections of non-communicable disease and health care costs among HIV-positive persons in Italy and the U.S.A.: A modelling study

scientific article published on 23 October 2017

Proportion and factors associated with recent HIV infection in a cohort of patients seen for care in Italy over 1996-2014: Data from the ICONA Foundation Study cohort

scientific article published on 5 December 2017

Randomized trial of DRV/r or LPV/r QD monotherapy vs maintaining a PI/r-based antiretroviral regimen in persons with suppressed HIV replication

scientific article

Rate of CD4+ cell count increase over periods of viral load suppression: relationship with the number of previous virological failures

scientific article published in August 2010

Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settings.

scientific article published in September 2009

Refining criteria for selecting candidates for a safe lopinavir/ritonavir or darunavir/ritonavir monotherapy in HIV-infected virologically suppressed patients

scientific article

Relative prognostic value of self-reported adherence and plasma NNRTI/PI concentrations to predict virological rebound in patients initially responding to HAART.

scientific article published in April 2004

Relevance of Interleukin-6 and D-Dimer for Serious Non-AIDS Morbidity and Death among HIV-Positive Adults on Suppressive Antiretroviral Therapy

scientific article

Reply to Manfredi

scientific article published on 7 November 2014

Response to First-Line Ritonavir-Boosted Protease Inhibitors (PI/r)-Based Regimens in HIV Positive Patients Presenting to Care with Low CD4 Counts: Data from the Icona Foundation Cohort

scientific article

Resumption of HIV replication is associated with monocyte/macrophage derived cytokine and chemokine changes: results from a large international clinical trial

scientific article

Risk of clinical progression among patients with immunological nonresponse despite virological suppression after combination antiretroviral treatment

scientific article published on March 2013

Risk of developing specific AIDS-defining illnesses in patients coinfected with HIV and hepatitis C virus with or without liver cirrhosis

scientific article published on August 2009

Risk of failure in patients with 215 HIV-1 revertants starting their first thymidine analog-containing highly active antiretroviral therapy

scientific article published on January 2004

Role of hepatitis C virus (HCV) viremia and HCV genotype in the immune recovery from highly active antiretroviral therapy in a cohort of antiretroviral-naive HIV-infected individuals

scientific article published on 5 May 2005

Role of serum free light chains in predicting HIV-associated non-Hodgkin lymphoma and Hodgkin's lymphoma and its correlation with antiretroviral therapy

scientific article published on 20 June 2012

Self-Reported Sexual Dysfunction Is Frequent Among HIV-Infected Persons and Is Associated with Suboptimal Adherence to Antiretrovirals

article

Sequence analysis of in vivo defective interfering-like RNA of influenza A H1N1 pandemic virus

scientific article

Switch of predicted HIV-1 tropism in treated subjects and its association with disease progression

scientific article published on November 2016

Switching to dual/monotherapy determines an increase in CD8+ in HIV-infected individuals: an observational cohort study.

scientific article

The association between detected drug resistance mutations and CD4(+) T-cell decline in HIV-positive individuals maintained on a failing treatment regimen

scientific article published on 19 June 2017

The association between serum biomarkers and disease outcome in influenza A(H1N1)pdm09 virus infection: results of two international observational cohort studies

scientific article

The association of high-sensitivity c-reactive protein and other biomarkers with cardiovascular disease in patients treated for HIV: a nested case-control study

scientific article published on 03 September 2013

The effects of HIV-1 subtype and ethnicity on the rate of CD4 cell count decline in patients naive to antiretroviral therapy: a Canadian-European collaborative retrospective cohort study

scientific article

The management of hepatitis B virus/HIV-1 co-infected patients starting their first HAART regimen. Treating two infections for the price of one drug?

scientific article

The potential of antimicrobials to induce thrombocytopenia in critically ill patients: data from a randomized controlled trial

scientific article (publication date: 2013)

Thymidine analogue mutation profiles: factors associated with acquiring specific profiles and their impact on the virological response to therapy

scientific article published in January 2005

Timing of antiretroviral therapy initiation after a first AIDS-defining event: temporal changes in clinical attitudes in the ICONA cohort

scientific article

Transmitted Drug Resistant HIV-1 and Association With Virologic and CD4 Cell Count Response to Combination Antiretroviral Therapy in the EuroSIDA Study

scientific article published in July 2008

Transmitted HIV-1 drug resistance in a large international cohort using next-generation sequencing: results from the Strategic Timing of Antiretroviral Treatment (START) study

scientific article published on 25 December 2020

Treatment discontinuation in HIV-1-infected individuals starting their first-line HAART after 2008: data from the ICONA Foundation Study Cohort

scientific article

Triglyceride/HDL ratio and its impact on the risk of diabetes mellitus development during ART.

scientific article published on 5 June 2016

Triple-class virologic failure in HIV-infected patients undergoing antiretroviral therapy for up to 10 years

scientific article published in March 2010

Viral tropism by geno2pheno as a tool for predicting CD4 decrease in HIV-1-infected naive patients with high CD4 counts

scientific article published on 31 January 2012

Virologic and immunologic response to regimens containing nevirapine or efavirenz in combination with 2 nucleoside analogues in the Italian Cohort Naive Antiretrovirals (I.Co.N.A.) study

scientific article

Virologic correlates of adherence to antiretroviral medications and therapeutic failure.

scientific article

Virological monitoring and resistance to first-line highly active antiretroviral therapy in adults infected with HIV-1 treated under WHO guidelines: a systematic review and meta-analysis

scientific article published on July 2009

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