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List of works by Antony R. Young

4-thiothymidine sensitization of DNA to UVA offers potential for a novel photochemotherapy ⬇️

scientific article published on November 2, 2011

5-MOP induced protection against epidermal DNA damage by ultraviolet radiation in human skin

scientific article published on 01 January 1990

A Commercial Sunscreen's Protection Against Ultraviolet Radiation-induced Immunosuppression is More Than 50% Lower Than Protection Against Sunburn in Humans

scientific article published on 01 January 2003

A Distinct Genotype of XP Complementation Group A: Surprisingly Mild Phenotype Highly Prevalent in Northern India/Pakistan/Afghanistan

article

A broad-spectrum sunscreen prevents cumulative damage from repeated exposure to sub-erythemal solar ultraviolet radiation representative of temperate latitudes

scientific article published on 11 June 2009

A comparison of the phototumorigenic potential of 8-MOP and 5-MOP in hairless albino mice exposed to solar simulated radiation

scientific article published on 01 May 1983

A single exposure of solar simulated radiation suppresses contact hypersensitivity responses both locally and systemically in humans: quantitative studies with high-frequency ultrasound

scientific article published on 01 July 1998

A sun holiday is a sunburn holiday

scientific article published on 01 August 2013

A sunscreen's labeled sun protection factor may overestimate protection at temperate latitudes: a human in vivo study.

scientific article published on 10 June 2010

ASTHMA - comparing the impact of vitamin D versus UVR on clinical and immune parameters.

scientific article published on 16 January 2017

Aberrant gene expression with deficient apoptotic keratinocyte clearance may predispose to polymorphic light eruption

scientific article published on 29 June 2017

Action spectra and chromophores for lethal photosensitization of Candida albicans by DNA monoadducts formed by 8-methoxypsoralen and monofunctional furocoumarins.

scientific article published in December 1989

Acute effects of UVR on human eyes and skin.

scientific article

An action spectrum (290-320 nm) for TNFalpha protein in human skin in vivo suggests that basal-layer epidermal DNA is the chromophore.

scholarly article

An action spectrum for 8-MOP induced sunburn cells in mammalian epidermis

scientific article published on 01 May 1981

An action spectrum for lethal photosensitization of Candida albicans by 8-MOP after low-dose broad-band UV-A irradiation; an action spectrum for 8-MOP 4',5'-monoadducts

scientific article published on 01 August 1987

An evaluation of nalidixic acid film as a UV-A radiation dosimeter

scientific article published on 01 March 1983

An optimal method for experimental provocation of polymorphic light eruption.

scientific article published on March 2004

Are broad-spectrum sunscreens necessary for immunoprotection?

scientific article published on October 2003

Author Correction: Vitamin E inhibits the UVAI induction of "light" and "dark" cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes.

scientific article published on 19 March 2018

Children sustain high levels of skin DNA photodamage, with a modest increase of serum 25(OH)D3 , after a summer holiday in Northern Europe.

scientific article published on 24 April 2018

Chromophores in human skin

scientific article published on May 1997

Comparative quantification of IL-1beta, IL-10, IL-10r, TNFalpha and IL-7 mRNA levels in UV-irradiated human skin in vivo

scientific article published on 01 June 2000

Comparative studies on the photosensitizing potency of 5-methoxypsoralen and 8-methoxypsoralen as measured by cytolysis in Paramecium caudatum and Tetrahymena pyriformis, and growth inhibition and survival in Candida albicans

scientific article published on 01 January 1982

DNA damage in UV-irradiated human skin in vivo: automated direct measurement by image analysis (thymine dimers) compared with indirect measurement (unscheduled DNA synthesis) and protection by 5-methoxypsoralen.

scientific article published in March 1993

Dark cyclobutane pyrimidine dimers are formed in the epidermis of Fitzpatrick skin types I/II and VI in vivo after exposure to solar simulated radiation

scientific article published on 26 December 2020

Deep phenotyping of 89 xeroderma pigmentosum patients reveals unexpected heterogeneity dependent on the precise molecular defect

scientific article published on 16 February 2016

Detection of UVR-induced DNA damage in mouse epidermis in vivo using alkaline elution

scientific article published on 01 February 1995

Determinants of personal ultraviolet-radiation exposure doses on a sun holiday.

scientific article published on May 2013

Determinants of vitamin D status in long-term renal transplant patients

article

Diffuse Reflectance Spectroscopy as a Reliable Means of Comparing Ultraviolet Radiation-induced Erythema in Extreme Skin Colors

scientific article published on 04 July 2018

Do sunscreens help?

scientific article published on 01 March 2000

Dose and time effects of solar-simulated ultraviolet radiation on the in vivo human skin transcriptome

scientific article published on 16 September 2019

Early changes in dermal collagen of mice exposed to chronic UVB irradiation and the effects of a UVB sunscreen

scientific article published on 01 December 1988

Effect of sunscreen application under maximal-use conditions on plasma concentration of sunscreen active ingredients: a critical appraisal

scientific article published on 13 December 2019

Effects of piperine analogues on stimulation of melanocyte proliferation and melanocyte differentiation

article

Effects of solar simulated radiation on the human immune system: influence of phototypes and wavebands

scientific article published on 01 January 2002

Effects of solar-simulated radiation dose fractionation on CD1a+ Langerhans cells and CD11b+ macrophages in human skin

scientific article published on 01 August 2001

Environmental effects of ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2017.

scientific article

Environmental effects of stratospheric ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2019

scientific article published on 04 May 2020

Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, Update 2020

scientific article published in 2021

Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, Update 2021

scientific article published on 21 February 2022

Enzyme therapy of xeroderma pigmentosum: safety and efficacy testing of T4N5 liposome lotion containing a prokaryotic DNA repair enzyme

scientific article published on 01 June 1996

Everyday sunscreen use may compromise vitamin D in temperate climes: reply from authors

scientific article published on 20 December 2019

Failure of UVR dose reciprocity for skin tumorigenesis in hairless mice treated with 8-methoxypsoralen

Furocoumarin‐induced Epidermal Melanogenesis Does Not Protect Against Skin Photocarcinogenesis in Hairless Mice ⬇️

scientific article published on January 1, 1998

Genotoxicity of bergapten and bergamot oil in Saccharomyces cerevisiae

scientific article published on 01 November 1990

Human erythema and matrix metalloproteinase-1 mRNA induction, in vivo, share an action spectrum which suggests common chromophores

scientific article published on 14 November 2011

Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate

article

Human melanocytes and keratinocytes exposed to UVB or UVA in vivo show comparable levels of thymine dimers.

scientific article

Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cells ⬇️

scientific article published on September 2, 2011

Improved protection against solar-simulated radiation-induced immunosuppression by a sunscreen with enhanced ultraviolet A protection

scientific article published on 01 April 2000

In situ repair of cyclobutane pyrimidine dimers and 6-4 photoproducts in human skin exposed to solar simulating radiation

scientific article published on 01 March 1999

In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen

scientific article published on 01 November 1990

Induction of mRNA for matrix metalloproteinase 1 and tissue inhibitor of metalloproteinases 1 in human skin in vivo by solar simulated radiation

scientific article published on 01 June 2001

Inhibition of UV radiation-induced DNA damage by a 5-methoxypsoralen tan in human skin

scientific article published on 01 January 1988

Is psoralen-containing sunscreen tumorigenic in hairless mice?

scientific article published on 01 February 1984

Low-dose ultraviolet-B irradiation depletes human epidermal Langerhans cells

scientific article published on 01 December 1993

Matrix metalloproteinase-1 and skin ageing in smokers

scientific article published in The Lancet

Measurement of sunscreen immune protection factors in humans: a consensus paper

scientific article

Mechanisms of and variables affecting UVR photoadaptation in human skin

scientific article published on 01 December 2018

Melanin distribution in human epidermis affords localized protection against DNA photodamage and concurs with skin cancer incidence difference in extreme phototypes.

scientific article published on 2 February 2018

Melanin has a Small Inhibitory Effect on Cutaneous Vitamin D Synthesis: a Comparison of Extreme Phenotypes

scientific article published on 26 December 2019

Melanogenesis: a photoprotective response to DNA damage?

scientific article

Methods used to evaluate the immune protection factor of a sunscreen: advantages and disadvantages of different in vivo techniques.

scientific article

Modification of 5-methoxypsoralen phototumorigenesis by UVB sunscreens: a statistical and histologic study in the hairless albino mouse

scientific article published on 01 December 1987

Molecular photoprotection of human keratinocytes in vitro by the naturally occurring mycosporine-like amino acid (MAA) palythine.

scientific article

More about: Sunscreen use and duration of sun exposure: a double-blind, randomized trial

scientific article published on 01 September 2000

Mouse skin photosensitivity with dihaematoporphyrin ether (DHE) and aluminium sulphonated phthalocyanine (AlSPc): a comparative study

scientific article (publication date: March 1989)

Mycosporine-like Amino Acids for Skin Photoprotection.

scientific article

Novel aspects of intrinsic and extrinsic aging of human skin: beneficial effects of soy extract.

scientific article published in May 2005

Optimal sunscreen use, during a sun holiday with a very high ultraviolet index, allows vitamin D synthesis without sunburn

scientific article published on 24 May 2019

PUVA TREATMENT STRATEGIES AND CANCER RISK

scientific article published in The Lancet

Personal UVR exposure of farming families in four European countries.

scientific article published on 9 October 2015

Photoadaptation during Narrowband Ultraviolet-B Therapy Is Independent of Skin Type: A Study of 352 Patients

article

Photodamage to human skin by suberythemal exposure to solar ultraviolet radiation can be attenuated by sunscreens: a review ⬇️

scientific article published on November 1, 2010

Photophysical, photochemical and photobiological properties of pyrrolocoumarins; a new class of photoactive compounds.

scientific article

Photoprotection and 5-MOP photochemoprotection from UVR-induced DNA damage in humans: the role of skin type

scientific article published on 01 November 1991

Photoprotection and vitamin D status

scientific article published on 21 March 2010

Photoprotection by furocoumarin-induced melanogenesis against DNA photodamage in mouse epidermis in vivo

scientific article published on 01 March 1997

Phototoxic properties of perfumes containing bergamot oil on human skin: photoprotective effect of UVA and UVB sunscreens.

scientific article published in November 1990

Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model

scientific article published on 01 November 1990

Proceedings from a clinical roundtable

scientific article published on 01 November 2004

Protection by ultraviolet A and B sunscreens against in situ dipyrimidine photolesions in human epidermis is comparable to protection against sunburn.

scientific article published in July 2000

Quantitative assessment of epidermal melanogenesis in C3H/Tif hr/hr mice treated with topical furocoumarins and UVA radiation

scientific article published on 01 July 1994

Relationship between p53 codon 72 polymorphism and susceptibility to sunburn and skin cancer

scientific article

Relationship between the ability of sunscreens containing 2-ethylhexyl-4'-methoxycinnamate to protect against UVR-induced inflammation, depletion of epidermal Langerhans (Ia+) cells and suppression of alloactivating capacity of murine skin in vivo

scientific article published on 01 January 1994

Repeated Suberythemal UVB Preexposure Protects against High-Dose UVB-Induced Expression of Vitamin D Receptor Protein in Human Skin

scientific article published on 04 August 2011

Repeated ultraviolet exposure affords the same protection against DNA photodamage and erythema in human skin types II and IV but is associated with faster DNA repair in skin type IV.

scientific article published in May 2002

Senescence and sunscreens.

scientific article published on April 1990

Shining light on darker skins

scientific article published on 01 March 2019

Singlet oxygen yields of furocoumarins and related molecules--the effect of excitation wavelength

scientific article published on 01 December 1993

Some Light on the Photobiology of Vitamin D

scientific article published on 01 February 2010

Standardized protocols for photocarcinogenesis safety testing

scientific article

Sub-optimal Application of a High SPF Sunscreen Prevents Epidermal DNA Damage in Vivo

article

Sun and ski holidays improve vitamin D status, but are associated with high levels of DNA damage

scientific article published on 20 May 2014

Sun behaviour and personal UVR exposure among Europeans on short term holidays

scientific article published on 19 August 2015

Sun exposure and protection behavior of Danish farm children: parental influence on their children.

scientific article published on 21 April 2014

Sunlight, tanning booths, and vitamin D

scientific article published on 01 May 2005

Sunscreen applied at ≥ 2mg/cm during a sunny holiday prevents erythema; a biomarker of UVR-induced DNA damage and suppression of acquired immunity

scientific article published on 05 December 2018

Sunscreen photoprotection and vitamin D status

scientific article published on 15 July 2019

Sunscreens offer the same UVB protection factors for inflammation and immunosuppression in the mouse

scientific article published on 01 February 1997

Sunscreens with low sun protection factor inhibit ultraviolet B and A photoaging in the skin of the hairless albino mouse

scientific article published on 01 February 1991

Suppressed alloantigen presentation, increased TNF-alpha, IL-1, IL-1Ra, IL-10, and modulation of TNF-R in UV-irradiated human skin

scientific article published on 01 May 1999

Tanning in human skin types II and III offers modest photoprotection against erythema

scientific article published on 01 October 1998

The 0.8% ultraviolet B content of an ultraviolet A sunlamp induces 75% of cyclobutane pyrimidine dimers in human keratinocytes in vitro

scientific article published on 01 June 1999

The Detrimental Effects of Daily Sub-Erythemal Exposure on Human Skin In Vivo Can Be Prevented by a Daily-Care Broad-Spectrum Sunscreen

scientific article published on 02 November 2006

The UV/Visible Radiation Boundary Region (385-405 nm) Damages Skin Cells and Induces "dark" Cyclobutane Pyrimidine Dimers in Human Skin in vivo

scientific article published in Scientific Reports

The UVR wavelength dependence for lomefloxacin photosensitization of human skin

scientific article published on 01 February 1996

The action spectrum for induction of chronic actinic dermatitis is similar to that for sunburn inflammation

scientific article published on 01 December 1995

The acute effects of ultraviolet radiation on the blood transcriptome are independent of plasma 25OHD3.

scientific article

The biological effects of ozone depletion.

scientific article

The consequences for human health of stratospheric ozone depletion in association with other environmental factors

scientific article

The detection of cyclobutane thymine dimers, (6-4) photolesions and the Dewar photoisomers in sections of UV-irradiated human skin using specific antibodies, and the demonstration of depth penetration effects

scientific article published on 01 May 1995

The impact of skin colour on human photobiological responses

scientific article

The in situ repair kinetics of epidermal thymine dimers and 6-4 photoproducts in human skin types I and II

scientific article published on 01 June 1996

The molecular determinants of sunburn cell formation

scientific article published on 01 June 2001

The mycosporine-like amino acids porphyra-334 and shinorine are antioxidants and direct antagonists of Keap1-Nrf2 binding

scientific article published on 30 July 2018

The photochemistry and photobiology of bergamot oil as a perfume ingredient: an overview

scientific article published on 01 November 1990

The quantitation and kinetics of unscheduled (repair) DNA synthesis in ultraviolet-irradiated human skin by automated image analysis

scientific article published on 01 October 1996

The similarity of action spectra for thymine dimers in human epidermis and erythema suggests that DNA is the chromophore for erythema.

scientific article

The soluble eumelanin precursor 5,6-dihydroxyindole-2-carboxylic acid enhances oxidative damage in human keratinocyte DNA after UVA irradiation.

scientific article published on August 1999

The sunburn cell in hairless mouse epidermis: quantitative studies with UV-A radiation and mono- and bifunctional psoralens

scientific article published on 01 October 1982

The sunburn cell.

scientific article

The time of onset and duration of 5-methoxypsoralen photochemoprotection from UVR-induced DNA damage in human skin

scientific article published on 01 October 1994

To tan or not to tan

scientific article published on 01 May 1990

UV irradiation affects melanocyte stimulatory activity and protein binding of piperine.

scientific article published on November 2006

UV radiation, vitamin D and human health: an unfolding controversy introduction

scientific article

UVA hazards in skin associated with the use of tanning equipment

scientific article published on 01 April 1989

UVA sunbeds: tanning, photoprotection, acute adverse effects and immunological changes

scientific article published on 01 June 1989

UVA1 induces cyclobutane pyrimidine dimers but not 6-4 photoproducts in human skin in vivo.

scientific article published on 6 October 2011

UVA1 is skin deep: molecular and clinical implications.

scientific article

UVB-induced collagen changes in the skin of the hairless albino mouse

scientific article published on 01 February 1987

UVR modulates the steady-state levels of skin collagen transcripts in hairless mice

scientific article published on 01 November 1997

UVR radiometry of solar simulated radiation in experimental photocarcinogenesis studies

scientific article published on 01 January 1982

Ultraviolet A1 phototherapy: a British Photodermatology Group workshop report.

scientific article published on 25 January 2012

Ultraviolet radiation and the skin: Photobiology and sunscreen photoprotection.

scientific article

Ultraviolet radiation-induced erythema in human skin

scientific article published on 01 September 2002

Ultraviolet radiation-induced inflammation as a model for cutaneous hyperalgesia.

scientific article published in January 2004

Ultraviolet-B-induced mechanical hyperalgesia: A role for peripheral sensitisation.

scientific article

Ultraviolet-radiation-induced erythema and suppression of contact hypersensitivity responses in patients with polymorphic light eruption

scientific article published in February 2004

Upregulation of MMP12 and Its Activity by UVA1 in Human Skin: Potential Implications for Photoaging

article

Validation of the 'polymorphic light eruption severity index'

scientific article published on 01 August 2006

Vitamin E inhibits the UVAI induction of "light" and "dark" cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes.

scientific article published on 11 January 2018

[Lethal lymphocyte damage caused by angular psoralen derivatives]

scientific article published on 01 January 1983

cis-Urocanic Acid Enhances Prostaglandin E2 Release and Apoptotic Cell Death via Reactive Oxygen Species in Human Keratinocytes

article

cis-Urocanic acid initiates gene transcription in primary human keratinocytes.

scientific article

cis-Urocanic acid stimulates primary human keratinocytes independently of serotonin or platelet-activating factor receptors.

scientific article

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