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List of works by David Vilchez

A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells.

scientific article published on 13 November 2017

Author Correction: Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy

scientific article published on 13 May 2020

Author Correction: Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.

scientific article published on 3 July 2018

Author Correction: The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients

scientific article published on 17 February 2020

Carboxyl-terminal fragment of amyloid precursor protein and hydrogen peroxide induce neuronal cell death through different pathways.

scientific article published on 6 June 2006

Down's syndrome astrocytes have greater antioxidant capacity than euploid astrocytes.

scientific article published on November 2004

Embryonic stem cells: a novel paradigm to study proteostasis?

scientific article

FOXO4 is necessary for neural differentiation of human embryonic stem cells.

scientific article published on June 2013

Induced pluripotent stem cells from Huntington's disease patients: a promising approach to define and correct disease-related alterations

scientific article published on 01 May 2019

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

scientific article published on 6 March 2018

Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations

scientific article published on 01 December 2018

Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy.

scientific article published on 21 October 2007

Mechanisms of protein homeostasis (proteostasis) maintain stem cell identity in mammalian pluripotent stem cells

scientific article published on 26 July 2017

Mediation of organismal aging and somatic proteostasis by the germline

scientific article

Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.

scientific article published on 21 May 2018

Neurotoxic effects of trimethyltin and triethyltin on human fetal neuron and astrocyte cultures: a comparative study with rat neuronal cultures and human cell lines.

scientific article published on August 2004

Prostaglandin signals from adult germ stem cells delay somatic aging of Caenorhabditis elegans

scientific article published on 19 August 2019

Proteostasis and aging of stem cells

scientific article published on 03 October 2013

Proteostasis of Huntingtin in Health and Disease

scientific article published on 19 July 2017

RPN-6 determines C. elegans longevity under proteotoxic stress conditions

scientific article published in September 2012

Regulation of glycogen synthesis by the laforin-malin complex is modulated by the AMP-activated protein kinase pathway

scientific article published on 20 November 2007

Rewiring of the ubiquitinated proteome determines ageing in C. elegans

scientific article published on 28 July 2021

Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan

scientific article

The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells

scientific article published on 08 August 2019

The Mechanistic Links Between Proteasome Activity, Aging and Age-related Diseases

scientific article published on February 2014

The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy

scientific article published on 11 December 2019

The intrinsic chaperone network of Arabidopsis stem cells confers protection against proteotoxic stress

scientific article published on 30 July 2021

The role of protein clearance mechanisms in organismal ageing and age-related diseases.

scientific article

The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients

scientific article published in Nature Communications

The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes

scientific article published on 19 January 2016

The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells

scientific article published on 25 May 2020