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List of works by Lin Xu

1-Methyl-4-phenylpyridinium stereotactic infusion completely and specifically ablated the nigrostriatal dopaminergic pathway in rhesus macaque

scientific article published on 26 May 2015

A matrilineal genetic legacy from the last glacial maximum confers susceptibility to schizophrenia in Han Chinese

scientific article published on 2 June 2014

A mouse line for inducible and reversible silencing of specific neurons

scientific article

A neural circuit for comorbid depressive symptoms in chronic pain

scientific article published on 26 August 2019

A new method for piercing the tentorium cerebelli for implanting fragile electrodes into the brain stem in the rhesus monkey (Macaca mulatta).

scientific article published on 11 December 2013

A quantitative approach to developing Parkinsonian monkeys (Macaca fascicularis) with intracerebroventricular 1-methyl-4-phenylpyridinium injections

scientific article

A study of N-methyl-D-aspartate receptor gene (GRIN2B) variants as predictors of treatment-resistant major depression

scientific article published on 11 October 2013

A-type GABA receptor as a central target of TRPM8 agonist menthol

scientific article

Abnormal anxiety- and depression-like behaviors in mice lacking both central serotonergic neurons and pancreatic islet cells.

scientific article

Abnormal resting-state activities and functional connectivities of the anterior and the posterior cortexes in medication-naïve patients with obsessive-compulsive disorder

scientific article (publication date: 2013)

Actin polymerization-dependent increase in synaptic Arc/Arg3.1 expression in the amygdala is crucial for the expression of aversive memory associated with drug withdrawal.

scientific article published in August 2012

Acute behavioural stress facilitates long-term depression in temporoammonic-CA1 pathway

scientific article published in May 2006

Acute cannabinoids impair working memory through astroglial CB1 receptor modulation of hippocampal LTD.

scientific article

Acute ketamine induces hippocampal synaptic depression and spatial memory impairment through dopamine D1/D5 receptors

scientific article published on 14 March 2013

Acute low-dose melamine affects hippocampal synaptic plasticity and behavior in rats

scientific article published on 19 August 2012

Amplitude/frequency of spontaneous mEPSC correlates to the degree of long-term depression in the CA1 region of the hippocampal slice

scientific article published on July 2005

Antistress effect of TRPV1 channel on synaptic plasticity and spatial memory.

scientific article

Atg5- and Atg7-dependent autophagy in dopaminergic neurons regulates cellular and behavioral responses to morphine

scientific article

Behavioural stress facilitates the induction of long-term depression in the hippocampus

scientific article published in May 1997

Brain-derived neurotrophic factor levels and bipolar disorder in patients in their first depressive episode: 3-year prospective longitudinal study

scientific article

Chronic clomipramine treatment reverses core symptom of depression in subordinate tree shrews

scientific article

Chronic constant light-induced hippocampal late-phase long-term potentiation impairment in vitro is attenuated by antagonist of D1/D5 receptors

scientific article

Chronic morphine treatment impaired hippocampal long-term potentiation and spatial memory via accumulation of extracellular adenosine acting on adenosine A1 receptors.

scientific article published in April 2010

Coincident activity of converging pathways enables simultaneous long-term potentiation and long-term depression in hippocampal CA1 network in vivo

scientific article

Complement factor H and susceptibility to major depressive disorder in Han Chinese

scientific article published on 3 March 2016

Convergent and divergent intranetwork and internetwork connectivity patterns in patients with remitted late-life depression and amnestic mild cognitive impairment

scientific article published on 10 August 2016

Correction: 1-Methyl-4-Phenylpyridinium Stereotactic Infusion Completely and Specifically Ablated the Nigrostriatal Dopaminergic Pathway in Rhesus Macaque

scientific article published on 8 January 2016

Corticosterone Signaling and a Lateral Habenula-Ventral Tegmental Area Circuit Modulate Compulsive Self-Injurious Behavior in a Rat Model

scientific article published on 14 May 2018

Corticosterone regulates fear memory via Rac1 activity in the hippocampus.

scientific article published on 18 May 2016

Decreased regional homogeneity in schizophrenia: a resting state functional magnetic resonance imaging study.

scientific article published in January 2006

Delineation of early and later adult onset depression by diffusion tensor imaging

scientific article

Despair-associated memory requires a slow-onset CA1 long-term potentiation with unique underlying mechanisms

scientific article

Dissociated large-scale functional connectivity networks of the precuneus in medication-naïve first-episode depression

scientific article published on 20 March 2015

Distinct neurobehavioral consequences of prenatal exposure to sulpiride (SUL) and risperidone (RIS) in rats.

scientific article published on 15 September 2007

Dynamic changes in orbitofrontal neuronal activity in rats during opiate administration and withdrawal.

scientific article published on 27 December 2005

Effect of repeated ipsapirone treatment on hippocampal excitatory synaptic transmission in the freely behaving rat: role of 5-HT1A receptors and relationship to anxiolytic effect

scientific article published in March 1997

Effects of pentylenetetrazol-induced brief convulsive seizures on spatial memory and fear memory.

scientific article published on 30 June 2009

Effects of unconditioned and conditioned aversive stimuli in an intense fear conditioning paradigm on synaptic plasticity in the hippocampal CA1 area in vivo

scientific article published in January 2005

Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice

scientific article published on 2 May 2017

Enriched environment experience overcomes the memory deficits and depressive-like behavior induced by early life stress

scientific article published on 21 June 2006

Enriched environment treatment counteracts enhanced addictive and depressive-like behavior induced by prenatal chronic stress

scientific article published on 14 November 2006

Enriched environment treatment restores impaired hippocampal synaptic plasticity and cognitive deficits induced by prenatal chronic stress

scientific article published on 17 October 2006

Escitalopram Ameliorates Forskolin-Induced Tau Hyperphosphorylation in HEK239/tau441 Cells

scientific article

Escitalopram Ameliorates Tau Hyperphosphorylation and Spatial Memory Deficits Induced by Protein Kinase A Activation in Sprague Dawley Rats.

scientific article

Escitalopram attenuates β-amyloid-induced tau hyperphosphorylation in primary hippocampal neurons through the 5-HT1A receptor mediated Akt/GSK-3β pathway

scientific article published on 29 February 2016

Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia.

scientific article published on 2 October 2007

Exposure to chronic constant light impairs spatial memory and influences long-term depression in rats.

scientific article published in July 2007

Ferulic Acid Ameliorates Alzheimer's Disease-like Pathology and Repairs Cognitive Decline by Preventing Capillary Hypofunction in APP/PS1 Mice

scientific article published on 30 March 2021

Fluoxetine and S-citalopram inhibit M1 activation and promote M2 activation of microglia in vitro

scientific article

Fluoxetine reverses stress-induced fimbria-prefrontal long-term potentiation facilitation

scientific article published in February 2006

Fluoxetine treatment reverses the intergenerational impact of maternal separation on fear and anxiety behaviors

scientific article

Frontal and cingulate gray matter volume reduction in heroin dependence: optimized voxel-based morphometry

scientific article published on 15 June 2009

GABA transporter-1 activity modulates hippocampal theta oscillation and theta burst stimulation-induced long-term potentiation.

scientific article published in December 2009

Genome of the Chinese tree shrew

scientific article published on January 2013

Glucocorticoid receptor and protein/RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress

scientific article

Glutamate receptor 1 phosphorylation at serine 845 contributes to the therapeutic effect of olanzapine on schizophrenia-like cognitive impairments

scientific article

Glycine uptake regulates hippocampal network activity via glycine receptor-mediated tonic inhibition

scientific article

Hippocampal Administration of Levothyroxine Impairs Contextual Fear Memory Consolidation in Rats.

scientific article published on 31 July 2017

Hippocampal Atrophy in Systemic Lupus Erythematosus Patients without Major Neuropsychiatric Manifestations

scientific article published on 12 June 2020

Impaired contextual fear extinction and hippocampal synaptic plasticity in adult rats induced by prenatal morphine exposure

scientific article published on 5 June 2014

Influence of BCL2 gene in major depression susceptibility and antidepressant treatment outcome.

scientific article published on 25 November 2013

Inhibition of Rac1 Activity in the Hippocampus Impairs the Forgetting of Contextual Fear Memory

scientific article

Inhibition of Rac1 activity in the hippocampus impaired extinction of contextual fear

scientific article published on 18 June 2016

Interaction between behavioral despair and addictive behaviors in rats

scientific article published on 16 October 2010

Interference of TRPV1 function altered the susceptibility of PTZ-induced seizures

scientific article

LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in experimental autoimmune encephalomyelitis mice

scientific article

Lead exposure through gestation-only caused long-term learning/memory deficits in young adult offspring

scientific article published in November 2003

Light exposure before learning improves memory consolidation at night

scientific article

Long-term effects of controllability or the lack of it on coping abilities and stress resilience in the rat.

scientific article

Maternal separation exaggerates spontaneous recovery of extinguished contextual fear in adult female rats

scientific article published on 18 April 2014

Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation.

scientific article published on 20 August 2015

MiRNA-206 and BDNF genes interacted in bipolar I disorder

scientific article published on 3 April 2014

Morphine conditioned place preference depends on glucocorticoid receptors in both hippocampus and nucleus accumbens

scientific article published in January 2006

Morphine induces Beclin 1- and ATG5-dependent autophagy in human neuroblastoma SH-SY5Y cells and in the rat hippocampus

scientific journal article

Morphine withdrawal modifies antinociceptive effects of acute morphine in rats.

scientific article published on 5 June 2006

N-methyl-D-aspartate receptor-dependent long-term potentiation in CA1 region affects synaptic expression of glutamate receptor subunits and associated proteins in the whole hippocampus

scientific article published on 12 June 2006

NMDA and D1 receptors are involved in one-trial tolerance to the anxiolytic-like effects of diazepam in the elevated plus maze test in rats

scientific article published on 21 May 2015

NR2B-containing N-methyl-D-aspartate subtype glutamate receptors regulate the acute stress effect on hippocampal long-term potentiation/long-term depression in vivo

scientific article published in August 2006

Nicotinic acid activates the capsaicin receptor TRPV1: Potential mechanism for cutaneous flushing.

scientific article

Offline memory reprocessing: involvement of the brain's default network in spontaneous thought processes

scientific article published on 17 March 2009

Opiate withdrawal modifies synaptic plasticity in subicular-nucleus accumbens pathway in vivo

scientific article published on 4 December 2006

Opioid addiction and withdrawal differentially drive long-term depression of inhibitory synaptic transmission in the hippocampus.

scientific article published on 05 May 2015

Opposite effective connectivity in the posterior cingulate and medial prefrontal cortex between first-episode schizophrenic patients with suicide risk and healthy controls.

scientific article

Periaqueductal Grey differential modulation of Nucleus Accumbens and Basolateral Amygdala plasticity under controllable and uncontrollable stress

scientific article

Prefrontal white matter abnormalities in young adult with major depressive disorder: a diffusion tensor imaging study.

scientific article published on 31 July 2007

Prenatal stress modifies hippocampal synaptic plasticity and spatial learning in young rat offspring

scientific article published in January 2006

Protective effect of APOE epsilon 2 on intrinsic functional connectivity of the entorhinal cortex is associated with better episodic memory in elderly individuals with risk factors for Alzheimer's disease

scientific article published on 14 August 2016

Protective efficacy of a single salvianolic acid A treatment on photothrombosis-induced sustained spatial memory impairments

scientific article

Publisher Correction: A neural circuit for comorbid depressive symptoms in chronic pain

scientific article published on 01 November 2019

Rapid-onset antidepressant efficacy of glutamatergic system modulators: the neural plasticity hypothesis of depression.

scientific article published on 06 December 2014

Reducing central serotonin in adulthood promotes hippocampal neurogenesis.

scientific article published on 3 February 2016

Resting-state brain alteration after a single dose of SSRI administration predicts 8-week remission of patients with major depressive disorder

scientific article published on 4 October 2016

Schizophrenia patients and their healthy siblings share disruption of white matter integrity in the left prefrontal cortex and the hippocampus but not the anterior cingulate cortex.

scientific article published on 29 July 2009

Sensory input is required for callosal axon targeting in the somatosensory cortex

scientific article

Significantly decreased mRNA levels of BDNF and MEK1 genes in treatment-resistant depression

scientific article published on July 2014

Spatial exploration induces a persistent reversal of long-term potentiation in rat hippocampus

scientific article published in August 1998

Spatial learning and memory impairments are associated with increased neuronal activity in 5XFAD mouse as measured by manganese-enhanced magnetic resonance imaging

scientific article

Stereotaxic 18F-FDG PET and MRI templates with three-dimensional digital atlas for statistical parametric mapping analysis of tree shrew brain

scientific article

Stress and long-term synaptic depression.

scientific article

Stress enables synaptic depression in CA1 synapses by acute and chronic morphine: possible mechanisms for corticosterone on opiate addiction.

scientific article published in March 2004

Synaptic P-Rex1 signaling regulates hippocampal long-term depression and autism-like social behavior

scientific article

Synaptic neurotransmission depression in ventral tegmental dopamine neurons and cannabinoid-associated addictive learning

scientific article

The Small GTPase Rac1 Contributes to Extinction of Aversive Memories of Drug Withdrawal by Facilitating GABAA Receptor Endocytosis in the vmPFC.

scientific article

The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats

scientific article

The first observation of seasonal affective disorder symptoms in Rhesus macaque.

scientific article

The interhemispheric CA1 circuit governs rapid generalisation but not fear memory

scientific article published on 19 December 2017

The role of the GABAA receptor Alpha 1 subunit in the ventral hippocampus in stress resilience

scientific article published on 18 September 2019

The stress experience dependent long-term depression disassociated with stress effect on spatial memory task.

scientific article published in August 2003

Unilateral hippocampal inactivation or lesion selectively impairs remote contextual fear memory.

scientific article published on 2 August 2016

White matter abnormalities in first-episode, treatment-naive young adults with major depressive disorder

scientific article

White matter integrity of the whole brain is disrupted in first-episode schizophrenia.

scientific article published in January 2006

Whole-brain spatial organization of hippocampal single-neuron projectomes

scientific article published on 01 February 2024

Whole-scale neurobehavioral assessments of photothrombotic ischemia in freely moving mice.

scientific article

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