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List of works by Philip G. Knight

'Free' inhibin α subunit is expressed by bovine ovarian theca cells and its knockdown suppresses androgen production

scientific article published on 24 December 2019

A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-alphaC and follistatin during pregnancy

scientific article published on 01 December 1998

Active immunisation against inhibin promotes a recurrent increase in litter size in sheep

scientific article published in January 1994

Active immunization of heifers against inhibin: effects on plasma concentrations of gonadotrophins, steroids and ovarian follicular dynamics during prostaglandin-synchronized cycles

scientific article published on 01 March 1994

Activin A and inhibin A as possible endocrine markers for pre-eclampsia

scientific article published on 01 May 1997

Alterations in amounts of different forms of inhibin during follicular atresia

scientific article published on 01 June 1994

Alterations in intrafollicular levels of different molecular mass forms of inhibin during development of follicular- and luteal-phase dominant follicles in heifers

scientific article published on 01 February 1996

Alterations in intrafollicular regulatory factors and apoptosis during selection of follicles in the first follicular wave of the bovine estrous cycle.

scientific article

Anastomosis of the ovarian vein to the hepatic portal vein in sheep induces ovarian hyperstimulation associated with increased LH pulsatility, but only in the absence of the contralateral ovary

scientific article published on 01 May 2000

Association between ovarian follicle development and pregnancy rates in dairy cows undergoing spontaneous oestrous cycles.

scientific article published in May 2004

Attenuation by an opioid agonist of the oestradiol-induced LH surge in anoestrous ewes and its reversal by naloxone

scientific article

Bone morphogenetic protein (BMP) ligands and receptors in bovine ovarian follicle cells: actions of BMP-4, -6 and -7 on granulosa cells and differential modulation of Smad-1 phosphorylation by follistatin.

scientific article published on February 2004

Bone morphogenetic protein-6 enhances gonadotrophin-dependent progesterone and inhibin secretion and expression of mRNA transcripts encoding gonadotrophin receptors and inhibin/activin subunits in chicken granulosa cells.

scientific article

Bone morphogenetic proteins (BMP) -4, -6, and -7 potently suppress basal and luteinizing hormone-induced androgen production by bovine theca interna cells in primary culture: could ovarian hyperandrogenic dysfunction be caused by a defect in thecal

scientific article published on 29 December 2004

Bovine follicle development is associated with divergent changes in activin-A, inhibin-A and follistatin and the relative abundance of different follistatin isoforms in follicular fluid

scientific article published in February 2006

Changes in expression of bone morphogenetic proteins (BMPs), their receptors and inhibin co-receptor betaglycan during bovine antral follicle development: inhibin can antagonize the suppressive effect of BMPs on thecal androgen production.

scientific article published on 25 August 2010

Changes in hypothalamic monoamine concentrations accompany the progesterone-induced release of luteinizing hormone in the domestic hen.

scientific article

Changes in inhibin-A (alpha-beta A dimer) and total alpha inhibin in the peripheral circulation and ovaries of rats after gonadotrophin-induced follicular development and during the normal oestrous cycle

scientific article published on 01 November 1995

Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy

scientific article published on 01 September 1996

Changes in plasma concentrations of immunoreactive inhibin, progesterone, and bioactive gonadotrophin during pregnancy in the marmoset monkey

scientific article published on 01 January 1994

Changes in plasma inhibin A levels during sexual maturation in the female chicken and the effects of active immunization against inhibin alpha-subunit on reproductive hormone profiles and ovarian function.

scientific article

Chicken ovulation cycle.

scientific article published on December 1984

Circulating concentrations of inhibin-related proteins during the ovulatory cycle of the domestic fowl (Gallus domesticus) and after induced cessation of egg laying

scientific article published on 01 July 2000

Circulating inhibins and activin A during GnRH-analogue down-regulation and ovarian hyperstimulation with recombinant FSH for in-vitro fertilization-embryo transfer

scientific article published in December 1996

Circulating insulin-like factor 3 (INSL3) in healthy and infertile women

scientific article published on 05 September 2013

Comparison of bioactivities, binding properties and intrafollicular levels of bovine follistatins

scientific article published on 11 May 2015

Comparison of the effects of crude and highly purified bovine inhibin (Mr 32,000) on plasma concentrations of FSH and LH in chronically ovariectomized prepubertal heifers

scientific article published on 01 April 1990

Concentrations of immunoreactive luteinizing hormone releasing hormone in discrete brain regions of the cockerel: effects of castration and testosterone replacement therapy

scientific article published on 01 March 1983

Day 5 inhibin B levels in a treatment cycle are predictive of IVF outcome.

scientific article published in June 2002

Decline in serum follicle-stimulating hormone concentrations alters key intrafollicular growth factors involved in selection of the dominant follicle in heifers

scientific article published on 01 December 1997

Demonstration of a nonsteroidal factor in human follicular fluid that attenuates the self-priming action of gonadotropin-releasing hormone on pituitary gonadotropes.

scientific article published in April 1990

Demonstration of a suppressive effect of inhibin alpha-subunit on the developmental competence of in vitro matured bovine oocytes

scientific article published in March 1999

Development and application of a two-site enzyme immunoassay for the determination of 'total' activin-A concentrations in serum and follicular fluid

scientific article published on 01 February 1996

Development of a two-site immunoradiometric assay for dimeric inhibin using antibodies against chemically synthesized fragments of the alpha and beta subunit

scientific article published on 01 May 1991

Development, validation and application of a two-site enzyme-linked immunosorbent assay for activin-AB

scientific article

Differential changes in inhibin A, activin A, and total alpha-subunit levels in granulosa and thecal layers of developing preovulatory follicles in the chicken

scientific article published on 01 March 1998

Differential control of immunoreactive alpha-inhibin and progesterone production by marmoset luteal cells in vitro: evidence for a paracrine action of alpha-inhibin on basal and gonadotropin-stimulated progesterone production.

scientific article

Differential effects of activin A on basal and gonadotrophin-induced secretion of inhibin A and progesterone by granulosa cells from preovulatory (F1-F3) chicken follicles.

scientific article

Differential expression of mRNAs encoding the putative inhibin co-receptor (betaglycan) and activin type-I and type-II receptors in preovulatory and prehierarchical follicles of the laying hen ovary

scientific article published in February 2006

Dysregulation of granulosal bone morphogenetic protein receptor 1B density is associated with reduced ovarian reserve and the age-related decline in human fertility.

scientific article published on 20 January 2016

Effect of active immunization of heifers against inhibin on plasma FSH concentrations, ovarian follicular development and ovulation rate

scientific article published on 01 July 1992

Effect of dominant follicle persistence on follicular fluid oestradiol and inhibin and on oocyte maturation in heifers

scientific article published in July 1999

Effect of gonadectomy on the concentrations of catecholamines in discrete areas of the diencephalon of the domestic fowl

scientific article published on 01 June 1981

Effect of mifepristone (RU486) on the pituitary response to gonadotrophin releasing hormone in women

scientific article published in December 1996

Effects of active immunization against a synthetic peptide sequence of the inhibin alpha-subunit on plasma gonadotrophin concentrations, ovulation rate and lambing rate in ewes

scientific article published in May 1992

Effects of active immunization of sheep against an amino terminal peptide of the inhibin alpha C subunit on intrafollicular levels of activin A, inhibin A and follistatin

scientific article published in April 1998

Effects of androgens, progesterone and their antagonists on the developmental competence of in vitro matured bovine oocytes

scientific article published in July 2000

Effects of bovine follicular fluid on gonadotrophin secretion in intact and chronically ovariectomized ewes before and after desensitization of pituitary gonadotrophs to gonadotrophin-releasing hormone

scientific article published in June 1988

Effects of bovine follicular fluid on the secretion of LH and FSH in inhibin-immunized seasonally anoestrous ewes

scientific article published on 01 March 1991

Effects of inhibin-related peptides and oestradiol on androstenedione and progesterone secretion by bovine theca cells in vitro ⬇️

scientific article published on June 1, 1995

Effects of ovarian follicle ablation on FSH, oestradiol and inhibin A concentrations and growth of other follicles in sheep.

scientific article published in January 2002

Effects of passive immunization against oestradiol-17 beta on some endocrine values of the male lamb

scientific article

Effects of supplementary treatment with bovine growth hormone on hormonal and ovulatory responses to inhibin immunization in ewes

scientific article published on 01 July 1997

Enzyme immunoassays for inhibins, activins and follistatins.

scientific article

Evidence for an inhibitory role of bone morphogenetic protein(s) in the follicular-luteal transition in cattle

scientific article published on 20 October 2008

Evidence for the involvement of central catecholaminergic mechanisms in mediating the preovulatory surge of luteinizing hormone in the domestic hen.

scientific article published in August 1982

Evidence for the involvement of central conversion of testosterone to oestradiol-17 beta in the regulation of luteinizing hormone secretion in the cockerel.

scientific article

Evidence that most of the radioimmunoassayable inhibin secreted by the corpus luteum of the common marmoset monkey is of a non-dimeric form

scientific article published on 01 October 1992

Evidence that the bovine ovary secretes large amounts of monomeric inhibin alpha subunit and its isolation from bovine follicular fluid

scientific article published on 01 May 1989

Expression of bovine inhibin beta subunit in Escherichia coli

scientific article published on 01 January 1991

Follicle wave growth in cattle.

scientific article

Follicular expression of pro-inflammatory cytokines tumour necrosis factor-α (TNFα), interleukin 6 (IL6) and their receptors in cattle: TNFα, IL6 and macrophages suppress thecal androgen production in vitro.

scientific article

Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production

scientific article published on 25 March 2013

Functional significance of the signal transduction pathways Akt and Erk in ovarian follicles: in vitro and in vivo studies in cattle and sheep.

scientific article

Gonadotrophin surge-attenuating factor bioactivity is present in follicular fluid from naturally cycling women

scientific article published in January 1995

Gonadotrophins modulate hormone secretion and steady-state mRNA levels for activin receptors (type I, IIA, IIB) and inhibin co-receptor (betaglycan) in granulosa and theca cells from chicken prehierarchical and preovulatory follicles

scientific article published on 01 June 2007

Granulosa Cell Apoptosis in the Ovarian Follicle-A Changing View

scientific article published on 2 March 2018

Granulosal and thecal expression of bone morphogenetic protein- and activin-binding protein mRNA transcripts during bovine follicle development and factors modulating their expression in vitro

scientific article published on 05 August 2011

Gremlin, Noggin, Chordin and follistatin differentially modulate BMP induced suppression of androgen secretion by bovine ovarian theca cells

scientific article published on 01 October 2018

Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes

scientific article published on 01 December 2018

Higher gonadotrophin surge-attenuating factor bioactivity is found in small follicles from superovulated women.

scientific article

Hypothalamic contents of LHRH and catecholamines during the ovulatory cycle of the hen (Gallus domesticus).

scientific article published in May 1984

Immunohistochemical localization of inhibin/activin alpha, betaA and betaB subunits and follistatin in bovine oocytes during in vitro maturation and fertilization.

scientific article

Increased concentrations of immunoreactive inhibin during conception cycles in the marmoset monkey: suppression with an LHRH antagonist and cloprostenol

scientific article published on 01 March 1991

Infertility and ovarian follicle reserve depletion are associated with dysregulation of the FSH and LH receptor density in human antral follicles

scientific article published on 7 February 2017

Influence of mutations affecting gonadotropin production or responsiveness on expression of inhibin subunit mRNA and protein in the mouse ovary

scientific article

Inhibin immunoneutralization by antibodies raised against synthetic peptide sequences of inhibin alpha subunit: effects on gonadotrophin concentrations and ovulation rate in sheep

scientific article published on 01 January 1990

Inhibin-A in Down's syndrome pregnancies: revised estimate of standard deviation

scientific article published on 01 March 1997

Intra-ovarian roles of activins and inhibins ⬇️

scientific article published on August 15, 2012

Involvement of Bone Morphogenetic Proteins (BMP) in the Regulation of Ovarian Function.

scientific article published on 8 March 2018

Involvement of endogenous opioid peptides in the neuroendocrine response of ewe lambs to the introduction of a ram.

scientific article

Measurement of dimeric inhibin using a modified two-site immunoradiometric assay specific for oxidized (Met O) inhibin

scientific article published on 01 June 1994

Measurement of dimeric inhibins and effects of active immunization against inhibin alpha-subunit on plasma hormones and testis morphology in the developing cockerel

scientific article published on 01 July 2000

Measurement of inhibin-A (alpha beta A dimer) during the oestrous cycle, after manipulation of ovarian activity and during pregnancy in ewes

scientific article published on 01 May 1998

Measurement of serum concentrations of inhibin-A (alpha-beta A dimer) during human pregnancy

scientific article published on 01 April 1995

Modulation of sex hormone secretion in cows by acute infection with bovine viral diarrhoea virus.

scientific article published in February 2002

Modulatory actions of activin-A and follistatin on the developmental competence of in vitro-matured bovine oocytes

scientific article published in February 1998

Modulatory effects of gonadotrophins and insulin-like growth factor on the secretion of inhibin A and progesterone by granulosa cells from chicken preovulatory (F1-F3) follicles.

scientific article

Myostatin is expressed in bovine ovarian follicles and modulates granulosal and thecal steroidogenesis

scientific article published on 01 October 2018

Oocyte-mediated suppression of follicle-stimulating hormone- and insulin-like growth factor-induced secretion of steroids and inhibin-related proteins by bovine granulosa cells in vitro: possible role of transforming growth factor alpha

scientific article published on March 2003

Ovarian expression of insulin-like peptide 3 (INSL3) and its receptor (RXFP2) during development of bovine antral follicles and corpora lutea and measurement of circulating INSL3 levels during synchronized estrous cycles.

scientific article

Prenatal screening for Down's syndrome using inhibin-A as a serum marker

scientific article published on 01 February 1996

Relationship between follicle size and gonadotrophin surge attenuating factor (GnSAF) bioactivity during spontaneous cycles in women

scientific article published in July 2001

Relationships between the level of atresia and inhibin contents (alpha subunit and alpha-beta dimer) in morphologically dominant follicles during their growing and regressing phases of development in cattle

scientific article published on 01 February 1993

Release of LHRH in vitro and anterior pituitary responsiveness to LHRH in vivo during sexual maturation in pullets (Gallus domesticus).

scientific article published in May 1985

Seasonal variations in the developmental competence of bovine oocytes matured in vitro

scientific article published in April 2006

Serum concentrations of dimeric inhibin during the spontaneous human menstrual cycle and after treatment with exogenous gonadotrophin

scientific article published on 01 September 1994

Stimulation of immunoreactive inhibin production by preimplantation embryos during early pregnancy in the marmoset monkey (Callithrix jacchus)

scientific article published on 01 September 1992

The ability of steroid-free bovine follicular fluid to suppress FSH secretion and delay ovulation persists in heifers actively immunized against inhibin

scientific article published in January 1993

The anti-epileptic drug valproic acid (VPA) inhibits steroidogenesis in bovine theca and granulosa cells in vitro

scientific article

The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction

scientific journal article

The effect of exogenous gonadotropins on ovarian function in goats actively immunized against inhibin

scientific article published on 14 September 2011

The effect of gonadotrophins with differing LH/FSH ratios on the secretion of the various species of inhibin in women receiving IVF.

scientific article published in June 2001

The effect of ovarian reserve and receptor signalling on granulosa cell apoptosis during human follicle development

scientific article published on 4 November 2017

The global effect of follicle-stimulating hormone and tumour necrosis factor α on gene expression in cultured bovine ovarian granulosa cells

scientific article published on 28 January 2014

The long-term effect of active immunization against inhibin in goats

scientific article published on 31 August 2008

The reproductive response of rams to thyroidectomy: mediation by impaired inhibin feedback rather than a change in LH pulsatility.

scientific article published in September 2003

Transcriptomal profiling of bovine ovarian granulosa and theca interna cells in primary culture in comparison with their in vivo counterparts.

scientific article

Treatment of ovariectomized heifers with bovine follicular fluid specifically suppresses pituitary levels of FSH-beta mRNA

scientific article published on 01 September 1989

Variation in pituitary expression of mRNAs encoding the putative inhibin co-receptor (betaglycan) and type-I and type-II activin receptors during the chicken ovulatory cycle.

scientific article published in September 2005

Variation in the ovarian reserve is linked to alterations in intrafollicular estradiol production and ovarian biomarkers of follicular differentiation and oocyte quality in cattle.

scientific article published on 21 January 2009

Variations in hypothalamic luteinizing hormone releasing hormone content and release in vitro and plasma concentrations of luteinizing hormone and testosterone in developing cockerels.

scientific article published on November 1983

Women with poor response to IVF have lowered circulating gonadotrophin surge-attenuating factor (GnSAF) bioactivity during spontaneous and stimulated cycles.

scientific article published in March 2002

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