List of works - Alex Boussioutas

2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer

scientific article published in December 2012

A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer

scientific article

A cohort study and meta-analysis of the evidence for consideration of Lauren subtype when prescribing adjuvant or palliative chemotherapy for gastric cancer

scientific article published on 23 July 2020

A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets ⬇️

scientific article published on 7 February 2012

A signature predicting poor prognosis in gastric and ovarian cancer represents a coordinated macrophage and stromal response

scientific article published on 21 March 2014

A systematic review of risk-reducing cancer surgery outcomes for hereditary cancer syndromes

scientific article published on 25 June 2019

Acceptability and accuracy of a non-endoscopic screening test for Barrett's oesophagus in primary care: cohort study

scientific article

An orthotopic mouse model of gastric cancer invasion and metastasis.

scientific article published on 16 January 2018

Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

scientific article published on 22 February 2013

Audit of adherence to GI screening recommendations for Lynch Syndrome Patients

Augmented gp130-mediated cytokine signalling accompanies human gastric cancer progression

scientific article published in October 2007

Becoming and being a parent with an inherited predisposition to diffuse gastric cancer: A qualitative study of young adults with a <i>CDH1</i> pathogenic variant

scientific article published in 2022

CD10 and Das1: a biomarker study using immunohistochemistry to subtype gastric intestinal metaplasia

scientific article published on 21 April 2022

Cancer risks for MLH1 and MSH2 mutation carriers

scientific article

Cell graph neural networks enable the precise prediction of patient survival in gastric cancer

scientific article published in 2022

Clinical problem-solving. Spot diagnosis

scientific article

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer

scientific article published on 26 June 2012

Contribution of the -Omics Era to Our Understanding of Preinvasive Disease and Progression to Cancer

scientific article published on 26 August 2010

Cost-effectiveness of family history-based colorectal cancer screening in Australia.

scientific article

Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients

scientific article

Current and potential uses for DNA microarrays in transplantation medicine: lessons from other disciplines.

scientific article

Current mismatch repair deficiency tumor testing practices and capabilities: A survey of Australian pathology providers

article

DEMoS: a deep learning-based ensemble approach for predicting the molecular subtypes of gastric adenocarcinomas from histopathological images

scientific article published in 2022

DNA methylation in peripheral blood and risk of gastric cancer: a prospective nested case-control study

scientific article published on 21 September 2020

Defective macrophage handling of Escherichia coli in Crohn's disease

scientific article published on August 2015

Determining epithelial contribution to in vivo mesenchymal tumour expression signature using species-specific microarray profiling analysis of xenografts.

scientific article published in February 2013

Dietary Intake of Nutrients Involved in One-Carbon Metabolism and Risk of Gastric Cancer: A Prospective Study

scientific article published on 15 March 2019

Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer

article

Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer.

scientific article

Early relapses after adjuvant chemotherapy suggests primary chemoresistance in diffuse gastric cancer.

scientific article published on 18 September 2017

Family history-based colorectal cancer screening in Australia: A modelling study of the costs, benefits, and harms of different participation scenarios

article

Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations

scientific article published on 08 January 2019

Gastric involvement of plasmacytoma associated with t(4:14) and chromosome 13 deletion

scientific article published in January 2006

Gastrointestinal: Tuberculosis of the sigmoid colon-a cautionary tale

scientific article published on 20 October 2011

Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort.

scientific article published on 19 February 2016

Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers

scientific article

Hereditary diffuse gastric cancer: updated clinical practice guidelines

scientific article published on 01 August 2020

High-dimensional analyses reveal a distinct role of T-cell subsets in the immune microenvironment of gastric cancer

scientific article published on 05 May 2020

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

scientific article

IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization.

scientific article published on 21 June 2019

Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer

scientific article published in May 2014

Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil

scientific article published on 14 May 2013

Imaging of goblet cells as a marker for intestinal metaplasia of the stomach by one-photon and two-photon fluorescence endomicroscopy

scientific article published in November 2009

Immunological battlefield in gastric cancer and role of immunotherapies

scientific article

Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer

scientific article published on 24 April 2007

Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically

scientific article published on August 2013

Intestinal metaplasia: a premalignant lesion involved in gastric carcinogenesis.

scientific article published on February 2009

Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy

scientific article

Lamina propria macrophage phenotypes in relation to Escherichia coli in Crohn's disease.

scientific article published on 3 July 2015

Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry

scientific article published on 02 September 2019

Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome

scientific article published on 10 April 2016

Non-endoscopic screening biomarkers for Barrett's oesophagus: from microarray analysis to the clinic

scientific article published on 2 August 2009

Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization

scientific article published in March 2005

Oncogenic pathway combinations predict clinical prognosis in gastric cancer.

scientific article published on 02 October 2009

Pathophysiology of Hereditary Diffuse Gastric Cancer

scientific article published in 2015

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant

scientific article

Predictors of outcome after surgery for gastric cancer in a Western cohort.

scientific article

Premalignant lesions and gastric cancer: Current understanding

scientific article published on 01 September 2019

Preoperative Diagnosis of Lynch Syndrome With DNA Mismatch Repair Immunohistochemistry on a Diagnostic Biopsy

scientific article published in December 2011

Processed pseudogenes acquired somatically during cancer development

scientific article published on 09 April 2014

Quantification and characterization of mucosa-associated and intracellular Escherichia coli in inflammatory bowel disease.

scientific article

Revised Australian national guidelines for colorectal cancer screening: family history

article

Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study.

scientific article

Risk of colorectal cancer for carriers of mutations in MUTYH, with and without a family history of cancer

scientific article published on 17 January 2014

Risk of metachronous colon cancer following surgery for rectal cancer in mismatch repair gene mutation carriers

scientific article

Role of p53 in the progression of gastric cancer

scientific article published on December 2014

Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives

scientific article

SFRP4 drives invasion in gastric cancer and is an early predictor of recurrence

scientific article published on 04 December 2020

Safety and Acceptability of Esophageal Cytosponge Cell Collection Device in a Pooled Analysis of Data From Individual Patients

scientific article published in March 2019

Screening participation for people at increased risk of colorectal cancer due to family history: a systematic review and meta-analysis

scientific article published on September 2013

Screening participation predictors for people at familial risk of colorectal cancer: a systematic review

scientific article published on May 2013

Screening practices of Australian men and women categorized as "at or slightly above average risk" of colorectal cancer

scientific article

Screening practices of unaffected people at familial risk of colorectal cancer

scientific article published on 26 October 2011

Second harmonic generation imaging via nonlinear endomicroscopy.

scientific article

Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas. ⬇️

scientific article

TOPGEAR: A Randomized, Phase III Trial of Perioperative ECF Chemotherapy with or Without Preoperative Chemoradiation for Resectable Gastric Cancer: Interim Results from an International, Intergroup Trial of the AGITG, TROG, EORTC and CCTG.

scientific article published on 23 March 2017

TOPGEAR: a randomised phase III trial of perioperative ECF chemotherapy versus preoperative chemoradiation plus perioperative ECF chemotherapy for resectable gastric cancer (an international, intergroup trial of the AGITG/TROG/EORTC/NCIC CTG).

scientific article published on 21 July 2015

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The challenges of gene expression microarrays for the study of human cancer

scientific article

The conundrum of quality in colonoscopy

scientific article published in April 2018

The interleukin-6 family cytokine interleukin-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development.

scientific article

The predicted impact and cost-effectiveness of systematic testing of people with incident colorectal cancer for Lynch syndrome

scientific article published on 08 October 2019

The unfolded protein response is activated in Helicobacter-induced gastric carcinogenesis in a non-cell autonomous manner

scientific article

Topological and Functional Discovery in a Gene Coexpression Meta-Network of Gastric Cancer

scientific article published in January 2006

Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts

scientific article published on 6 June 2016

mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice

scientific article published on 16 January 2013

‘Why don’t I need a colonoscopy?’: A novel approach to communicating risks and benefits of colorectal cancer screening

scientific article published in June 2018

List of works by Alex Boussioutas

2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer

A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer

A cohort study and meta-analysis of the evidence for consideration of Lauren subtype when prescribing adjuvant or palliative chemotherapy for gastric cancer

A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets ⬇️

A signature predicting poor prognosis in gastric and ovarian cancer represents a coordinated macrophage and stromal response

A systematic review of risk-reducing cancer surgery outcomes for hereditary cancer syndromes

Acceptability and accuracy of a non-endoscopic screening test for Barrett's oesophagus in primary care: cohort study

An orthotopic mouse model of gastric cancer invasion and metastasis.

Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

Audit of adherence to GI screening recommendations for Lynch Syndrome Patients

Augmented gp130-mediated cytokine signalling accompanies human gastric cancer progression

Becoming and being a parent with an inherited predisposition to diffuse gastric cancer: A qualitative study of young adults with a <i>CDH1</i> pathogenic variant

CD10 and Das1: a biomarker study using immunohistochemistry to subtype gastric intestinal metaplasia

Cancer risks for MLH1 and MSH2 mutation carriers

Cell graph neural networks enable the precise prediction of patient survival in gastric cancer

Clinical problem-solving. Spot diagnosis

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

Comprehensive Characterization of Cancer Driver Genes and Mutations

Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer

Contribution of the -Omics Era to Our Understanding of Preinvasive Disease and Progression to Cancer

Cost-effectiveness of family history-based colorectal cancer screening in Australia.

Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients

Current and potential uses for DNA microarrays in transplantation medicine: lessons from other disciplines.

Current mismatch repair deficiency tumor testing practices and capabilities: A survey of Australian pathology providers

DEMoS: a deep learning-based ensemble approach for predicting the molecular subtypes of gastric adenocarcinomas from histopathological images

DNA methylation in peripheral blood and risk of gastric cancer: a prospective nested case-control study

Defective macrophage handling of Escherichia coli in Crohn's disease

Determining epithelial contribution to in vivo mesenchymal tumour expression signature using species-specific microarray profiling analysis of xenografts.

Dietary Intake of Nutrients Involved in One-Carbon Metabolism and Risk of Gastric Cancer: A Prospective Study

Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer

Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer.

Early relapses after adjuvant chemotherapy suggests primary chemoresistance in diffuse gastric cancer.

Family history-based colorectal cancer screening in Australia: A modelling study of the costs, benefits, and harms of different participation scenarios

Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations

Gastric involvement of plasmacytoma associated with t(4:14) and chromosome 13 deletion

Gastrointestinal: Tuberculosis of the sigmoid colon-a cautionary tale

Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort.

Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers

Hereditary diffuse gastric cancer: updated clinical practice guidelines

High-dimensional analyses reveal a distinct role of T-cell subsets in the immune microenvironment of gastric cancer

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization.

Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer

Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil

Imaging of goblet cells as a marker for intestinal metaplasia of the stomach by one-photon and two-photon fluorescence endomicroscopy

Immunological battlefield in gastric cancer and role of immunotherapies

Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer

Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically

Intestinal metaplasia: a premalignant lesion involved in gastric carcinogenesis.

Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy

Lamina propria macrophage phenotypes in relation to Escherichia coli in Crohn's disease.

Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry

Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome

Non-endoscopic screening biomarkers for Barrett's oesophagus: from microarray analysis to the clinic

Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization

Oncogenic pathway combinations predict clinical prognosis in gastric cancer.

Pathophysiology of Hereditary Diffuse Gastric Cancer

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant

Predictors of outcome after surgery for gastric cancer in a Western cohort.

Premalignant lesions and gastric cancer: Current understanding

Preoperative Diagnosis of Lynch Syndrome With DNA Mismatch Repair Immunohistochemistry on a Diagnostic Biopsy

Processed pseudogenes acquired somatically during cancer development

Quantification and characterization of mucosa-associated and intracellular Escherichia coli in inflammatory bowel disease.

Revised Australian national guidelines for colorectal cancer screening: family history

Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study.

Risk of colorectal cancer for carriers of mutations in MUTYH, with and without a family history of cancer

Risk of metachronous colon cancer following surgery for rectal cancer in mismatch repair gene mutation carriers

Role of p53 in the progression of gastric cancer

Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives

SFRP4 drives invasion in gastric cancer and is an early predictor of recurrence

Safety and Acceptability of Esophageal Cytosponge Cell Collection Device in a Pooled Analysis of Data From Individual Patients

Screening participation for people at increased risk of colorectal cancer due to family history: a systematic review and meta-analysis

Screening participation predictors for people at familial risk of colorectal cancer: a systematic review

Screening practices of Australian men and women categorized as "at or slightly above average risk" of colorectal cancer

Screening practices of unaffected people at familial risk of colorectal cancer

Second harmonic generation imaging via nonlinear endomicroscopy.

Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas. ⬇️

TOPGEAR: A Randomized, Phase III Trial of Perioperative ECF Chemotherapy with or Without Preoperative Chemoradiation for Resectable Gastric Cancer: Interim Results from an International, Intergroup Trial of the AGITG, TROG, EORTC and CCTG.

TOPGEAR: a randomised phase III trial of perioperative ECF chemotherapy versus preoperative chemoradiation plus perioperative ECF chemotherapy for resectable gastric cancer (an international, intergroup trial of the AGITG/TROG/EORTC/NCIC CTG).