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List of works by Dina C. Simes

A dual role for GRP in cardiovascular disease

scientific article published on 01 March 2019

Amentadione from the Alga <i>Cystoseira usneoides</i> as a Novel Osteoarthritis Protective Agent in an Ex Vivo Co-Culture OA Model

scientific article published on 07 December 2020

Assessment of protein digestive capacity and utilisation during ontogeny of Senegalese sole larvae: a tracer study using in vivo produced radiolabelled peptide fractions

scientific article published in January 2013

Characterization of osteocalcin (BGP) and matrix Gla protein (MGP) fish specific antibodies: validation for immunodetection studies in lower vertebrates

scientific article published on 15 December 2003

Chronic Kidney Disease Circulating Calciprotein Particles and Extracellular Vesicles Promote Vascular Calcification: A Role for GRP (Gla-Rich Protein).

scientific article published on 4 January 2018

Cloning and characterization of the cDNA and gene encoding Xenopus laevis osteocalcin.

scientific article

Cloning of matrix Gla protein in a marine cartilaginous fish, Prionace glauca: preferential protein accumulation in skeletal and vascular systems

scientific article published on 13 January 2006

Dysregulated fetuin-mineral complexes are linked to vascular calcification in chronic kidney disease: The role of Gla-rich protein

scientific article published in January 2017

Gla-Rich Protein (GRP) as an Early and Novel Marker of Vascular Calcification and Kidney Dysfunction in Diabetic Patients with CKD: A Pilot Cross-Sectional Study

scientific article published on 27 February 2020

Gla-rich Protein (GRP): A New Player In The Burden Of Vascular Calcification

Gla-rich protein (GRP), a new vitamin K-dependent protein identified from sturgeon cartilage and highly conserved in vertebrates

scientific article

Gla-rich protein acts as a calcification inhibitor in the human cardiovascular system.

scientific article published on 23 December 2014

Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: Implications for calcification-related chronic inflammatory diseases.

scientific article

Gla-rich protein is a novel vitamin K-dependent protein present in serum that accumulates at sites of pathological calcifications.

scientific article

Gla-rich protein is a potential new vitamin K target in cancer: evidences for a direct GRP-mineral interaction

scientific article

Gla-rich protein is involved in the cross-talk between calcification and inflammation in osteoarthritis

scientific article published on 4 September 2015

Identification of proteins with potential osteogenic activity present in the water-soluble matrix proteins from Crassostrea gigas nacre using a proteomic approach.

scientific article published in May 2012

Insights into the association of Gla-rich protein and osteoarthritis, novel splice variants and γ-carboxylation status

scientific article published on 28 May 2014

Isolation and characterisation of metallothionein from the clam Ruditapes decussatus

scientific article published in May 2003

Osteocalcin and matrix GLA protein in developing teleost teeth: identification of sites of mRNA and protein accumulation at single cell resolution

scientific article published on 01 August 2005

Osteocalcin and matrix Gla protein in zebrafish (Danio rerio) and Senegal sole (Solea senegalensis): comparative gene and protein expression during larval development through adulthood.

scientific article published on 2 February 2006

Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish.

scientific article

Structural Evidence of a Fourth Gla Residue in Fish Osteocalcin: Biological Implications†,‡

scientific article published on 01 February 2005

Sturgeon osteocalcin shares structural features with matrix Gla protein: evolutionary relationship and functional implications.

scientific article published on 24 July 2013

Teleost fish osteocalcin 1 and 2 share the ability to bind the calcium mineral phase

scientific article published on 2 November 2013

The interplay between mineral metabolism, vascular calcification and inflammation in Chronic Kidney Disease (CKD): challenging old concepts with new facts

scientific article published on 01 June 2019

Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling.

scientific article published on 21 March 2018

Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases

scientific article published on 03 January 2020

Vitamin K as a Powerful Micronutrient in Aging and Age-Related Diseases: Pros and Cons from Clinical Studies ⬇️

scientific article published on 25 August 2019

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