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List of works by Leonard Appleman

A Phase I study of bortezomib plus irinotecan in patients with advanced solid tumors

scientific article

A phase I study of foretinib, a multi-targeted inhibitor of c-Met and vascular endothelial growth factor receptor 2.

scientific article published on 14 May 2010

A phase I, open-label study of trebananib combined with sorafenib or sunitinib in patients with advanced renal cell carcinoma

scientific article

A phase i study of DMS612, a novel bifunctional alkylating agent

scientific article

Autophagy Inhibition to Augment mTOR Inhibition: a Phase I/II Trial of Everolimus and Hydroxychloroquine in Patients with Previously Treated Renal Cell Carcinoma

scientific article published on 11 January 2019

Calcium carbonate does not affect imatinib pharmacokinetics in healthy volunteers

scientific article published on 30 October 2013

Calcium carbonate does not affect nilotinib pharmacokinetics in healthy volunteers

scientific article published on 14 September 2013

DLK1: A Novel Target for Immunotherapeutic Remodeling of the Tumor Blood Vasculature ⬇️

scientific article published on July 30, 2013

Dominant‐negative p53 can restore tumorigenicity of L‐929 cells in immunocompetent mice ⬇️

scientific article published on November 15, 1995

Effect of a proton pump inhibitor on the pharmacokinetics of imatinib

scientific article published on September 2009

Helper T cell anergy: from biochemistry to cancer pathophysiology and therapeutics.

scientific article

Inhibiting autophagy: a novel approach for the treatment of renal cell carcinoma

scientific article published on July 2013

MET Signaling Pathway: A Rational Target for Cancer Therapy ⬇️

scientific article published on October 31, 2011

Mifepristone: pharmacology and clinical impact in reproductive medicine, endocrinology and oncology.

scientific article published on February 2010

Neoadjuvant Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin With Pegfilgrastim Support in Muscle-Invasive Urothelial Cancer: Pathologic, Radiologic, and Biomarker Correlates

scientific article published on 12 May 2014

Pharmacologic administration of interleukin-2.

scientific article

Phase 1 study of veliparib (ABT-888), a poly (ADP-ribose) polymerase inhibitor, with carboplatin and paclitaxel in advanced solid malignancies

scientific article published on 23 September 2019

Phase I and pharmacokinetic study of dasatinib and cetuximab in patients with advanced solid malignancies ⬇️

scientific article published on September 1, 2011

Phase I and pharmacokinetic study of the dolastatin-15 analogue tasidotin (ILX651) administered intravenously on days 1, 3, and 5 every 3 weeks in patients with advanced solid tumors

scientific article published on 01 November 2005

Phase I clinical trial of bortezomib in combination with gemcitabine in patients with advanced solid tumors

scientific article

Phase I clinical trial of the farnesyltransferase inhibitor BMS-214662 administered as a weekly 24 h continuous intravenous infusion in patients with advanced solid tumors

scientific article published on 13 December 2005

Rat adenocarcinoma 13762 expresses tumor rejection antigens but tumor-bearing animals exhibit tumor-specific immunosuppression

scientific article published on 01 November 1993

Rate and Determinants of Completing Neoadjuvant Chemotherapy in Medicare Beneficiaries With Bladder Cancer: A SEER-Medicare Analysis

scientific article published on 10 November 2018

Renal cell carcinoma from a transplanted allograft: two case reports and a review of the literature.

scientific article published on March 2008

Sarcomatoid Renal Cell Carcinoma: Population-Based Study of 879 Patients

scientific article published on 17 January 2019

Selective kinase inhibition with daily imatinib intensifies toxicity of chemotherapy in patients with solid tumours

scientific article published on 28 February 2006

The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment

scientific article

Tumors antigens encoded by oncogenes and the impact of oncogenes upon the immune responses.

scientific article published on May 1996

Tyrosine Kinase and Mammalian Target of Rapamycin Inhibitors in the Treatment of Advanced Renal Cell Carcinoma: Practical Clinical Implications of Pharmacologic Features

scientific article

Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas.

scientific article published on 21 October 2013

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