List of works - Kevin L. Legge

Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection

scientific article

Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice

scientific article published on 21 November 2011

Antigen Exposure History Defines CD8 T Cell Dynamics and Protection during Localized Pulmonary Infections

scientific article published on 27 January 2017

Chronic Ethanol Consumption Reduces Existing CD8 T Cell Memory and Is Associated with Lesions in Protection against Secondary Influenza A Virus Infections

scientific article published on 11 November 2019

Chronic ethanol exposure selectively inhibits the influenza-specific CD8 T cell response during influenza a virus infection

scientific article published on 26 August 2014

Chronic ethanol induces inhibition of antigen-specific CD8+ but not CD4+ immunodominant T cell responses following Listeria monocytogenes inoculation

scientific article published on 26 September 2008

Cutting edge: contribution of lung-resident T cell proliferation to the overall magnitude of the antigen-specific CD8 T cell response in the lungs following murine influenza virus infection

scientific article published on October 2009

Dendritic cells in chronic in vivo ethanol exposure models

scientific article published in January 2008

Diet-induced obesity does not impact the generation and maintenance of primary memory CD8 T cells

scientific article

Differential control of neonatal tolerance by antigen dose versus extended exposure and adjuvant.

scientific article

Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge

scientific article

Endoplasmic Reticulum Stress, A Potential Therapeutic Target For Influenza A Viral Infection

Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly

scientific article

Fetal exposure to ethanol has long-term effects on the severity of influenza virus infections

scientific article published on June 2009

IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

scientific article

Influenza A Virus Vaccination: Immunity, Protection, and Recent Advances Toward A Universal Vaccine

scientific article published on 03 August 2020

Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway.

scientific article published on 22 December 2011

Influenza-induced expression of functional tumor necrosis factor-related apoptosis-inducing ligand on human peripheral blood mononuclear cells

scientific article

Innate immune control and regulation of influenza virus infections

scientific article published on 30 July 2009

Lymph node dendritic cells control CD8+ T cell responses through regulated FasL expression

scientific article published in December 2005

Lymphopenia associated with highly virulent H5N1 virus infection due to plasmacytoid dendritic cell-mediated apoptosis of T cells

scientific article

Mechanisms by which chronic ethanol feeding limits the ability of dendritic cells to stimulate T-cell proliferation

scientific article

Natural Killer Cell Recruitment to the Lung During Influenza A Virus Infection Is Dependent on CXCR3, CCR5, and Virus Exposure Dose.

scientific article

Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension.

scientific article published on 17 August 2012

Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment

scientific article published on 25 October 2016

On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity

scientific article

Oseltamivir treatment prevents the increased influenza virus disease severity and lethality occurring in chronic ethanol consuming mice

scientific article

Peripheral regulation of T cells by dendritic cells during infection

scientific article published on August 2014

Plasmacytoid Dendritic Cells Require Direct Infection To Sustain the Pulmonary Influenza A Virus-Specific CD8 T Cell Response

scientific article published on 30 December 2015

Plasmacytoid dendritic cells enhance mortality during lethal influenza infections by eliminating virus-specific CD8 T cells

scientific article

Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T Cell Responses In Vivo.

scientific article

Presentation of a T cell receptor antagonist peptide by immunoglobulins ablates activation of T cells by a synthetic peptide or proteins requiring endocytic processing

scientific article

Primary and long-term B-cell responses in the upper airway and lung after influenza A virus infection.

scientific article

Protective CD8 T cell-mediated immunity against influenza A virus infection following influenza virus-like particle vaccination

scientific article published on 24 July 2013

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

scientific article published on July 2008

Pulmonary infection with influenza A virus induces site-specific germinal center and T follicular helper cell responses

scientific article (publication date: 2012)

Quantification of the frequency and multiplicity of infection of respiratory- and lymph node-resident dendritic cells during influenza virus infection

scientific article

Respiratory dendritic cells: maturation and migration following pulmonary influenza virus infection

Respiratory dendritic cells: mediators of tolerance and immunity

scientific article published on January 2007

T regulatory cells participate in the control of germinal centre reactions

scientific article published on 3 June 2011

The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL.

scientific article

List of works by Kevin L. Legge

Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection

Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice

Antigen Exposure History Defines CD8 T Cell Dynamics and Protection during Localized Pulmonary Infections

Chronic Ethanol Consumption Reduces Existing CD8 T Cell Memory and Is Associated with Lesions in Protection against Secondary Influenza A Virus Infections

Chronic ethanol exposure selectively inhibits the influenza-specific CD8 T cell response during influenza a virus infection

Chronic ethanol induces inhibition of antigen-specific CD8+ but not CD4+ immunodominant T cell responses following Listeria monocytogenes inoculation

Cutting edge: contribution of lung-resident T cell proliferation to the overall magnitude of the antigen-specific CD8 T cell response in the lungs following murine influenza virus infection

Dendritic cells in chronic in vivo ethanol exposure models

Diet-induced obesity does not impact the generation and maintenance of primary memory CD8 T cells

Differential control of neonatal tolerance by antigen dose versus extended exposure and adjuvant.

Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge

Endoplasmic Reticulum Stress, A Potential Therapeutic Target For Influenza A Viral Infection

Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly

Fetal exposure to ethanol has long-term effects on the severity of influenza virus infections

IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

Influenza A Virus Vaccination: Immunity, Protection, and Recent Advances Toward A Universal Vaccine

Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway.

Influenza-induced expression of functional tumor necrosis factor-related apoptosis-inducing ligand on human peripheral blood mononuclear cells

Innate immune control and regulation of influenza virus infections

Lymph node dendritic cells control CD8+ T cell responses through regulated FasL expression

Lymphopenia associated with highly virulent H5N1 virus infection due to plasmacytoid dendritic cell-mediated apoptosis of T cells

Mechanisms by which chronic ethanol feeding limits the ability of dendritic cells to stimulate T-cell proliferation

Natural Killer Cell Recruitment to the Lung During Influenza A Virus Infection Is Dependent on CXCR3, CCR5, and Virus Exposure Dose.

Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension.

Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment

On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity

Oseltamivir treatment prevents the increased influenza virus disease severity and lethality occurring in chronic ethanol consuming mice

Peripheral regulation of T cells by dendritic cells during infection

Plasmacytoid Dendritic Cells Require Direct Infection To Sustain the Pulmonary Influenza A Virus-Specific CD8 T Cell Response

Plasmacytoid dendritic cells enhance mortality during lethal influenza infections by eliminating virus-specific CD8 T cells

Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T Cell Responses In Vivo.

Presentation of a T cell receptor antagonist peptide by immunoglobulins ablates activation of T cells by a synthetic peptide or proteins requiring endocytic processing

Primary and long-term B-cell responses in the upper airway and lung after influenza A virus infection.

Protective CD8 T cell-mediated immunity against influenza A virus infection following influenza virus-like particle vaccination

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

Pulmonary infection with influenza A virus induces site-specific germinal center and T follicular helper cell responses

Quantification of the frequency and multiplicity of infection of respiratory- and lymph node-resident dendritic cells during influenza virus infection

Respiratory dendritic cells: maturation and migration following pulmonary influenza virus infection

Respiratory dendritic cells: mediators of tolerance and immunity

T regulatory cells participate in the control of germinal centre reactions

The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL.