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List of works by Laura E. Randle

Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice

scientific article

Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes.

scientific article published on 31 August 2005

Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice

scientific article published on 23 October 2007

Isoquine and Related Amodiaquine Analogues: A New Generation of Improved 4-Aminoquinoline Antimalarials ⬇️

scientific article published on November 6, 2003

Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture

scientific article published in PLoS ONE

Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver.

scientific article

The Generation, Detection, and Effects of Reactive Drug Metabolites ⬇️

scientific article published on October 22, 2012

The Metabolism and Toxicity of Furosemide in the Wistar Rat and CD-1 Mouse: a Chemical and Biochemical Definition of the Toxicophore

article

The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system

scientific article published on October 2008

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