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List of works by Adolfo García-Sastre

"Host immune response-inspired development of the influenza vaccine"

scientific article published on 20 April 2020

17β-estradiol protects primary macrophages against HIV infection through induction of interferon-alpha

scientific article

1918 and 2009 H1N1 influenza viruses are not pathogenic in birds

scientific article

2 methylate or not 2 methylate: viral evasion of the type I interferon response

scientific article published on February 1, 2011

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

scientific article published on 04 September 2020

292 p53 Transcriptionally activates IRF9 to enhance antiviral immunity

article published in 2008

5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication

scientific article

A Chimeric Influenza Virus Expressing an Epitope of Outer Membrane Protein F ofPseudomonas aeruginosaAffords Protection against Challenge withP. aeruginosain a Murine Model of Chronic Pulmonary Infection

scientific article published on August 1, 1998

A High-Resolution Look at Influenza Virus Antigenic Drift

scientific article published on 6 May 2016

A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals

scientific article published on 18 April 2020

A Newcastle Disease Virus (NDV) Expressing a Membrane-Anchored Spike as a Cost-Effective Inactivated SARS-CoV-2 Vaccine

scientific article published on 17 December 2020

A Newcastle disease virus (NDV) expressing membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine

scientific article published on 31 July 2020

A Newly Emerged Swine-Origin Influenza A(H3N2) Variant Dampens Host Antiviral Immunity but Induces Potent Inflammasome Activation.

scientific article

A Potent Anti-influenza Compound Blocks Fusion through Stabilization of the Prefusion Conformation of the Hemagglutinin Protein

scientific article

A RIG-I 2CARD-MAVS200 Chimeric Protein Reconstitutes IFN-β Induction and Antiviral Response in Models Deficient in Type I IFN Response.

scientific article

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

scientific article published on 30 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

journal article from 'bioRxiv' published in 2020

A Sendai virus-derived RNA agonist of RIG-I as a virus vaccine adjuvant.

scientific article

A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface

scientific article published on 01 May 2019

A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain

scientific article

A Universal Influenza Virus Vaccine Candidate Tested in a Pig Vaccination-Infection Model in the Presence of Maternal Antibodies

article

A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial

scientific article published on 07 December 2020

A combination in-ovo vaccine for avian influenza virus and Newcastle disease virus

scientific article published on 3 December 2007

A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cells

scientific article

A conserved influenza A virus nucleoprotein code controls specific viral genome packaging

scientific article published on 21 September 2016

A dual vaccine against influenza & Alzheimer's disease failed to enhance anti-β-amyloid antibody responses in mice with pre-existing virus specific memory

scientific article

A genetically engineered influenza A virus with ras-dependent oncolytic properties

scientific article published on November 15, 2001

A genome-wide CRISPR-Cas9 screen reveals the requirement of host cell sulfation for Schmallenberg virus infection

scientific article published on 10 June 2020

A household case evidences shorter shedding of SARS-CoV-2 in naturally infected cats compared to their human owners

scientific article published on 15 December 2020

A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesis

scientific article

A novel SUMOylation site in the influenza a virus NS1 protein identified with a highly sensitive FRET assay

scientific article published on 18 August 2020

A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses

scientific article (publication date: 9 March 2017)

A novel high-throughput cell-based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery

scientific article

A novel paramyxovirus?

scientific article published on January 2005

A plasmid-based reverse genetics system for influenza A virus.

scientific article published on June 1996

A reassortment-incompetent live attenuated influenza virus vaccine for protection against pandemic virus strains.

scientific article

A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice

scientific journal article

A serological assay to detect SARS-CoV-2 seroconversion in humans

scientific article published on 18 March 2020

A serological assay to detect SARS-CoV-2 seroconversion in humans

scientific article published on 12 May 2020

A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity.

scientific article

A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence.

scientific article published on 30 July 2014

A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission

scientific article

A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies

scientific article published on 14 September 2017

A viral-vectored RSV vaccine induces long-lived humoral immunity in cotton rats

scholarly article by Jessica L Grieves et al published 18 June 2018 in Vaccine

ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA.

scientific article published on 26 November 2015

ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon

scientific article published on 12 July 2013

Accumulation of CD11b⁺Gr-1⁺ cells in the lung, blood and bone marrow of mice infected with highly pathogenic H5N1 and H1N1 influenza viruses

scientific article

Activation and regulation of pathogen sensor RIG-I.

scientific article published on 23 August 2014

Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein

scientific article

Activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs) by human dendritic cells infected with an attenuated influenza A virus expressing a CTL epitope derived from the HER-2/neu proto-oncogene

scientific article

Active opioid use does not attenuate the humoral responses to inactivated influenza vaccine

scientific article published on 6 February 2016

Activity of human serum antibodies in an influenza virus hemagglutinin stalk-based ADCC reporter assay correlates with activity in a CD107a degranulation assay

scientific article published on 17 January 2020

Activity of influenza C virus O-acetylesterase with O-acetyl-containing compounds

scientific article

After the pandemic: perspectives on the future trajectory of COVID-19

scientific article published in 2021

Against the clock towards new Ebola virus therapies

scientific article

An HER2-Displaying Virus-Like Particle Vaccine Protects from Challenge with Mammary Carcinoma Cells in a Mouse Model

scientific article published on 20 May 2019

An Immunocompetent Mouse Model of Zika Virus Infection.

scientific article published in May 2018

An In Vitro Microneutralization Assay for SARS-CoV-2 Serology and Drug Screening

scientific article published on 01 September 2020

An enzymatic assay for detection of viral entry

scientific article published on June 2011

An enzymatic virus-like particle assay for sensitive detection of virus entry

scientific article

An infectious bat-derived chimeric influenza virus harbouring the entry machinery of an influenza A virus

scientific article published on 23 July 2014

An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation

scientific article published on 10 August 2020

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

scientific article published on 05 November 2020

An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoprotein

scientific article

Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus

scientific article

Animal models for COVID-19

scientific article published on 23 September 2020

Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)

scientific article published in 2023

Antagonism of type I interferon by flaviviruses

scientific article published on 30 May 2017

Antitumor properties of influenza virus vectors.

scientific article

Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection

scientific article

Antiviral innate immunity through the lens of systems biology

scientific article

Antiviral response in pandemic influenza viruses

scientific article

Apical budding of a recombinant influenza A virus expressing a hemagglutinin protein with a basolateral localization signal

scientific article published on April 2002

Arterivirus and nairovirus ovarian tumor domain-containing Deubiquitinases target activated RIG-I to control innate immune signaling

scientific article published on 9 November 2011

Assessment of influenza virus hemagglutinin stalk-based immunity in ferrets.

scientific article

Attenuated influenza virus construct with enhanced hemagglutinin protein expression

scientific article

Attenuated influenza virus vaccines with modified NS1 proteins

scientific article

Attenuation and immunogenicity in mice of temperature-sensitive influenza viruses expressing truncated NS1 proteins

scientific article published in October 2005

Attenuation of Influenza A Virus mRNA Levels by Promoter Mutations

scientific article published on August 1, 1998

Attenuation of equine influenza viruses through truncations of the NS1 protein

scientific article

Author Correction: Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

scientific article published on 16 June 2020

Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.

scientific article

Avian flu: Gain-of-function experiments on H7N9.

scientific article published in August 2013

Avian influenza A H10N8--a virus on the verge?

scientific article published on 5 February 2014

Bat influenza viruses transmit among bats but are poorly adapted to non-bat species

scientific article published on 16 September 2019

BioHealthBase: informatics support in the elucidation of influenza virus host pathogen interactions and virulence

scientific article

Blocking interhost transmission of influenza virus by vaccination in the guinea pig model

scientific article published on 19 January 2009

Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein.

scientific article published on 21 December 2017

Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines

scientific article published on 19 August 2008

Broadly Cross-Reactive, Nonneutralizing Antibodies against Influenza B Virus Hemagglutinin Demonstrate Effector Function-Dependent Protection against Lethal Viral Challenge in Mice

scientific article published on 05 March 2019

Broadly neutralizing antibodies target a haemagglutinin anchor epitope

scientific article published on 23 December 2021

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

scientific article published in 2021

COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms

scientific article (preprint) published on 22 June 2020

COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms

scientific article

COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms

scholarly article

CS17-5. Arteri- and nairovirus OTU domain-containing proteases target ubiquitin-regulated factors in the RLR-mediated innate immune signaling pathway

Cell biology: Beneficial lessons from viruses

scientific article published on 30 January 2013

Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing

scientific article (publication date: 2013)

Cellular localization and antigenic characterization of crimean-congo hemorrhagic fever virus glycoproteins

scientific article

Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza

scientific article

Characterization of HIV-1 entry inhibitors with broad activity against R5 and X4 viral strains

scientific article

Characterization of a mitochondrial-targeting signal in the PB2 protein of influenza viruses

scientific article published on 18 October 2005

Characterization of influenza virus variants with different sizes of the non-structural (NS) genes and their potential as a live influenza vaccine in poultry

scientific article

Characterization of swine-origin H1N1 canine influenza viruses

scientific article published on 01 January 2019

Characterization of the reconstructed 1918 Spanish influenza pandemic virus

scientific article

Characterizing Emerging Canine H3 Influenza Viruses

scientific article published on 14 April 2020

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor

scientific article published on 11 September 2011

Chemical intervention of influenza virus mRNA nuclear export

scientific article published on 02 April 2020

Chimeric Hemagglutinin-Based Influenza Virus Vaccines Induce Protective Stalk-Specific Humoral Immunity and Cellular Responses in Mice

article

Chimeric animal and plant viruses expressing epitopes of outer membrane protein F as a combined vaccine against Pseudomonas aeruginosa lung infection

scientific article published on 01 April 2000

Chimeric influenza A viruses with a functional influenza B virus neuraminidase or hemagglutinin

scientific article published on September 2003

Chimeric influenza viruses incorporating epitopes of outer membrane protein F as a vaccine against pulmonary infection with Pseudomonas aeruginosa

scientific article published on February 1, 1997

Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing.

scientific article

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis

scientific article published on 01 December 2018

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

scientific article published on 15 October 2020

Comparison of Heterologous Prime-Boost Strategies against Human Immunodeficiency Virus Type 1 Gag Using Negative Stranded RNA Viruses

scientific article

Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection

scientific article published on 06 July 2020

Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection

scientific article published on 17 October 2020

Comparison of biological and physical properties of human and animal A(H1N1) influenza viruses

scientific article

Complete-proteome mapping of human influenza A adaptive mutations: implications for human transmissibility of zoonotic strains.

scientific article

Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.

scientific article published on 6 April 2018

Constitutive resistance to viral infection in human CD141+ dendritic cells.

scientific article published on July 2017

Contribution of Double-Stranded RNA and CPSF30 Binding Domains of Influenza Virus NS1 to the Inhibition of Type I Interferon Production and Activation of Human Dendritic Cells

scientific article published on December 19, 2012

Contribution of NS1 effector domain dimerization to influenza A virus replication and virulence

scientific article

Contribution of the Purinergic Receptor P2X7 to Development of Lung Immunopathology during Influenza Virus Infection

scientific article published on 28 March 2017

Coronavirus Disease (COVID-19) hospitalized patients with acute kidney injury (AKI) treated with acute peritoneal dialysis do not have infectious PD effluent

scientific article published on 24 June 2020

Correction for Eduardo-Correia et al., ISG15 Is Counteracted by Vaccinia Virus E3 Protein and Controls the Proinflammatory Response against Viral Infection

scientific article

Correction: ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA

scientific article published on 2 March 2016

Correction: ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection

scientific article published on 13 October 2016

Correction: ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection.

scientific article published on 30 October 2013

Correction: The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

scientific article published on 18 April 2017

Corrigendum: Influenza virus mRNA trafficking through host nuclear speckles

scientific article

Corrigendum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

scientific article published on 8 July 2015

Cross-presenting CD103+ dendritic cells are protected from influenza virus infection

scientific article

Current status of COVID-19 (pre)clinical vaccine development

scientific article published on 14 July 2020

Cutting edge: a potent adjuvant effect of ligand to receptor activator of NF-kappa B gene for inducing antigen-specific CD8+ T cell response by DNA and viral vector vaccination

scientific article published on December 2003

Cytopathogenesis of vesicular stomatitis virus is regulated by the PSAP motif of M protein in a species-dependent manner

scientific article

DNA immunization of newborn mice with a plasmid-expressing nucleoprotein of influenza virus

scientific article published in January 1996

Defining the antibody cross-reactome directed against the influenza virus surface glycoproteins

scientific article

Defining the risk of SARS-CoV-2 variants on immune protection

scientific article published on 31 March 2022

Delivery of Chlamydia vaccines

scientific article

Dengue Virus Immunity Increases Zika Virus-Induced Damage during Pregnancy

scientific article published on 30 January 2019

Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.

scientific article published on 27 March 2017

Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling

scientific article

Detection of Respiratory Viruses and Subtype Identification of Influenza A Viruses by GreeneChipResp Oligonucleotide Microarray

scientific article

Development and Assessment of a Pooled Serum as Candidate Standard to Measure Influenza A Virus Group 1 Hemagglutinin Stalk-Reactive Antibodies

scientific article published on 09 November 2020

Development and characterization of a highly specific and sensitive SYBR green reverse transcriptase PCR assay for detection of the 2009 pandemic H1N1 influenza virus on the basis of sequence signatures

scientific article

Development of Novel Influenza Virus Vaccines and Vectors

scientific article published on August 1, 1997

Differences in antibody responses between trivalent inactivated influenza vaccine and live attenuated influenza vaccine correlate with the kinetics and magnitude of interferon signaling in children

scientific article

Differential Modulation of Innate Immune Responses in Human Primary Cells by Influenza A Viruses Carrying Human or Avian Nonstructural Protein 1

scientific article published on 12 December 2019

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species

scientific article

Differential inhibition of type I interferon induction by arenavirus nucleoproteins

scientific article published on 5 September 2007

Differential recognition of viral RNA by RIG-I

scientific article published on March 1, 2011

Differential requirement for the IKKβ/NF-κB signaling module in regulating TLR- versus RLR-induced type 1 IFN expression in dendritic cells

scientific article published on 23 July 2014

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

scientific article published on 24 July 2020

Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway

scientific article

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

scientific article (publication date: 2008)

Distinct cross-reactive B-cell responses to live attenuated and inactivated influenza vaccines

scientific article

Distinct patterns of B-cell activation and priming by natural influenza virus infection versus inactivated influenza vaccination.

scientific article

Divergent H7 immunogens offer protection from H7N9 virus challenge.

scientific article

ERRATUM: The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways.

scientific article

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

scientific article

Editorial overview: Emerging viruses: interspecies transmission: Expect the unexpected

scientific article published on 01 February 2019

Editorial overview: host-microbe interactions: viruses

scientific article published on 20 July 2015

Effect of anaesthesia and acute intestinal ischemia on serum beta-N-acetylhexosaminidase activity in rabbit as biological model

scientific article published in June 1992

Effect of cholecalciferol supplementation on inflammation and cellular alloimmunity in hemodialysis patients: data from a randomized controlled pilot trial

scientific article

Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis.

scientific article published on February 2002

Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine

scientific article

Emergence and Evolution of Novel Reassortant Influenza A Viruses in Canines in Southern China.

scientific article published on 5 June 2018

Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.

scientific article published on 5 June 2018

Engineered RNA viral synthesis of microRNAs

scientific article

Engineered viral vaccine constructs with dual specificity: avian influenza and Newcastle disease

scholarly article

Enhanced CD8+ T cell response to HIV-1 env by combined immunization with influenza and vaccinia virus recombinants

scientific article published in February 1999

Enhanced cellular immune responses to SIV Gag by immunization with influenza and vaccinia virus recombinants

scientific article published in May 2003

Enhanced oncolytic potency of vesicular stomatitis virus through vector-mediated inhibition of NK and NKT cells

scientific article

Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity

scientific article (publication date: 30 March 2017)

Enhancement of oncolytic properties of recombinant newcastle disease virus through antagonism of cellular innate immune responses

scientific article

Enhancement of the proapoptotic properties of newcastle disease virus promotes tumor remission in syngeneic murine cancer models

scientific article published on 11 March 2015

Enzymatic glycosidase activities in experimental obesity

scientific article published on September 1, 1992

Erratum to: Induction of type I interferon by RNA viruses: cellular receptors and their substrates

scientific article published on 17 February 2011

Erratum: Author Correction: Newcastle disease virus-based H5 influenza vaccine protects chickens from lethal challenge with a highly pathogenic H5N2 avian influenza virus.

scientific article

Erratum: Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

scientific article published in Nature

Erratum: Sunwoo, S.-Y. et al. A Universal Influenza Virus Vaccine Candidate Tested in a Pig Vaccination-Infection Model in the Presence of Maternal Antibodies. Vaccines 2018, 6(3), 64

article

Evasion of innate and adaptive immune responses by influenza A virus

scientific article

Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions.

scientific article

Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus.

scientific article

Expected and Unexpected Features of the Newly Discovered Bat Influenza A-like Viruses

scientific article published on 4 June 2015

Experimental infection of pigs with the human 1918 pandemic influenza virus

scientific article

Exponential enhancement of oncolytic vesicular stomatitis virus potency by vector-mediated suppression of inflammatory responses in vivo

scientific article published on 11 December 2007

Expression of a foreign protein by influenza A virus.

scientific article published on July 1994

Extrapulmonary tissue responses in cynomolgus macaques (Macaca fascicularis) infected with highly pathogenic avian influenza A (H5N1) virus.

scientific article

FACS-Mediated Isolation of Neuronal Cell Populations From Virus-Infected Human Embryonic Stem Cell-Derived Cerebral Organoid Cultures

article

Faculty of 1000 evaluation for A viral RNA structural element alters host recognition of nonself RNA

Faculty of 1000 evaluation for Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus

Faculty of 1000 evaluation for Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses

article

Faculty of 1000 evaluation for From the Cover: IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

article

Faculty of 1000 evaluation for Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

Faculty of 1000 evaluation for IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage

Faculty of 1000 evaluation for Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation

Faculty of 1000 evaluation for RIG-I Forms Signaling-Competent Filaments in an ATP-Dependent, Ubiquitin-Independent Manner

Faculty of 1000 evaluation for The DHX33 RNA Helicase Senses Cytosolic RNA and Activates the NLRP3 Inflammasome

Flow Cytometric and Cytokine ELISpot Approaches To Characterize the Cell-Mediated Immune Response in Ferrets following Influenza Virus Infection

scientific article published on 29 June 2016

Functional Characterization and Direct Comparison of Influenza A, B, C, and D NS1 Proteins in vitro and in vivo

scientific article published on 17 December 2019

Functional Effects of Cardiomyocyte Injury in COVID-19

scientific article published on 20 October 2021

Functional Genomic and Serological Analysis of the Protective Immune Response Resulting from Vaccination of Macaques with an NS1-Truncated Influenza Virus.

scientific article

Functional Landscape of SARS-CoV-2 Cellular Restriction

scientific article published on 30 September 2020

Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus.

scientific article

Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains.

scientific article

Fusion between Newcastle disease virus and erythrocyte ghosts using octadecyl Rhodamine B fluorescence assay produces dequenching curves that fit the sum of two exponentials

scientific article published on June 1994

Gain-of-Function Experiments on H7N9

scientific article published in Science

Gain-of-function experiments on H7N9.

scientific article published in August 2013

Gastrointestinal involvement attenuates COVID-19 severity and mortality

scientific article published on 09 September 2020

Generation of Recombinant Influenza Virus from Plasmid DNA

scientific article published on August 3, 2010

Genetic manipulation of negative-strand RNA virus genomes

scientific article

Genetic requirement for hemagglutinin glycosylation and its implications for influenza A H1N1 virus evolution

scientific article

Genetically engineered Newcastle disease virus for malignant melanoma therapy

scientific article

Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus

scientific article

Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus.

scientific article

Glycine 184 in nonstructural protein NS1 determines the virulence of influenza A virus strain PR8 without affecting the host interferon response

scientific article

Glycosylations in the globular head of the hemagglutinin protein modulate the virulence and antigenic properties of the H1N1 influenza viruses

scientific article

Gut microbiota manipulation during the prepubertal period shapes behavioral abnormalities in a mouse neurodevelopmental disorder model

scientific article published on 13 March 2020

H3N2 influenza virus infection induces broadly reactive hemagglutinin stalk antibodies in humans and mice

scientific article published on 13 February 2013

H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice.

scientific article

H5N1 virus: Transmission studies resume for avian flu.

scientific article published on 23 January 2013

H5N1, a wealth of knowledge to improve pandemic preparedness

scientific article

H7N9 influenza virus neutralizing antibodies that possess few somatic mutations

scientific article

H7N9 influenza viruses interact preferentially with α2,3-linked sialic acids and bind weakly to α2,6-linked sialic acids

scientific article published on 15 August 2013

HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells

scientific article

HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3.

scientific article

Hantaan virus nucleocapsid protein binds to importin alpha proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor kappa B.

scientific article

Hemagglutinin (HA) proteins from H1 and H3 serotypes of influenza A viruses require different antigen designs for the induction of optimal protective antibody responses as studied by codon-optimized HA DNA vaccines

scientific article

Hemagglutinin Stalk Immunity Reduces Influenza Virus Replication and Transmission in Ferrets

scientific article published on 30 December 2015

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

scientific article

Hemagglutinin stalk-based universal vaccine constructs protect against group 2 influenza A viruses.

scientific article published on 31 July 2013

Hemagglutinin-pseudotyped green fluorescent protein-expressing influenza viruses for the detection of influenza virus neutralizing antibodies

scientific article

Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses

scientific article

Hepatitis C Virus Drugs Simeprevir and Grazoprevir Synergize with Remdesivir to Suppress SARS-CoV-2 Replication in Cell Culture

scientific article

Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture

scientific article

Heterologous HA DNA vaccine prime--inactivated influenza vaccine boost is more effective than using DNA or inactivated vaccine alone in eliciting antibody responses against H1 or H3 serotype influenza viruses.

scientific article

Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responses

scientific article

Host modulators of H1N1 cytopathogenicity

scientific article

Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins

scientific article

Host-Specific NS5 Ubiquitination Determines Yellow Fever Virus Tropism

scientific article published on 28 June 2019

Host-range restriction of vaccinia virus E3L deletion mutant can be overcome in vitro, but not in vivo, by expression of the influenza virus NS1 protein

scientific article (publication date: 2011)

Host–pathogen interactions

Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses.

scientific article

Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air.

scientific article

Human Monoclonal Antibodies Potently Neutralize Zika Virus and Select for Escape Mutations on the Lateral Ridge of the Envelope Protein

scientific article published on 28 June 2019

Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response

scientific article (publication date: February 2014)

Human host factors required for influenza virus replication

scientific article

Human interactome of the influenza B virus NS1 protein.

scientific article published on 4 September 2017

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

scientific article

Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses

scientific article

Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements

scientific article

ICOS(+)PD-1(+)CXCR3(+) T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination

scientific article

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

scientific journal article

INFLUENZA VIRUSES (ORTHOMYXOVIRIDAE) | Molecular Biology

scholarly article by Peter Palese published in January 1999

IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein

scientific article (publication date: 23 March 2001)

ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection

scientific article (publication date: 2013)

ISG15 deficiency and increased viral resistance in humans but not mice

scientific article

ISG15 is counteracted by vaccinia virus E3 protein and controls the proinflammatory response against viral infection

scientific article published on 20 November 2013

ISRE-Reporter Mouse Reveals High Basal and Induced Type I IFN Responses in Inflammatory Monocytes

article

Identification and characterization of viral antagonists of type I interferon in negative-strand RNA viruses.

scientific article published in January 2004

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

scientific article

Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus

scientific article

Identification of cellular interaction partners of the influenza virus ribonucleoprotein complex and polymerase complex using proteomic-based approaches

scientific article published on February 2007

Identification of small molecules with type I interferon inducing properties by high-throughput screening

scientific article

Immunization with live attenuated influenza viruses that express altered NS1 proteins results in potent and protective memory CD8+ T-cell responses

scientific article

Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial

scientific article published on 17 October 2019

Immunologic characterization of a rhesus macaque H1N1 challenge model for candidate influenza virus vaccine assessment.

scientific article

In Vivo Replication and Pathogenesis of Vesicular Stomatitis Virus Recombinant M40 Containing Ebola Virus L-Domain Sequences

scientific article published on November 2012

In memoriam--Richard M. Elliott (1954-2015)

scientific article

In vivo ligands of MDA5 and RIG-I in measles virus-infected cells

scientific article

InTRIMsic immunity: Positive and negative regulation of immune signaling by tripartite motif proteins

scientific article

Inactivated influenza virus vaccines: the future of TIV and QIV.

scientific article published on 12 May 2017

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

scientific article published on 24 September 2020

Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling

scientific article

Increased influenza A virus sialidase activity with N-acetyl-9-O-acetylneuraminic acid-containing substrates resulting from influenza C virus O-acetylesterase action

scientific article published in September 1992

Increased serum N-acetyl-beta-D-glucosaminidase and alpha-D-mannosidase activities in obese subjects

scientific article published in October 1992

Increased viral loads and exacerbated innate host responses in aged macaques infected with the 2009 pandemic H1N1 influenza A virus

scientific article

Induction and Evasion of Type-I Interferon Responses during Influenza A Virus Infection

scientific article published on 06 July 2020

Induction and evasion of type I interferon responses by influenza viruses

scientific article published on October 21, 2011

Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination

scientific article published on March 2013

Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans.

scientific article

Induction of cellular immune responses to simian immunodeficiency virus gag by two recombinant negative-strand RNA virus vectors

scientific article published on September 2004

Induction of cross-reactive antibodies to novel H7N9 influenza virus by recombinant Newcastle disease virus expressing a North American lineage H7 subtype hemagglutinin

scientific article published on 22 May 2013

Induction of humoral and cellular immunity against influenza virus by immunization of newborn mice with a plasmid bearing a hemagglutinin gene

scientific article published in November 1997

Induction of immunological memory in baboons primed with DNA vaccine as neonates

scientific article

Induction of protective immunity against malaria by priming-boosting immunization with recombinant cold-adapted influenza and modified vaccinia Ankara viruses expressing a CD8+-T-cell epitope derived from the circumsporozoite protein of Plasmodium y

scientific article published on November 2003

Induction of type I interferon by RNA viruses: cellular receptors and their substrates

scientific article (publication date: November 2009)

Induction of type I interferon secretion through recombinant Newcastle disease virus expressing measles virus hemagglutinin stimulates antibody secretion in the presence of maternal antibodies

scientific article

Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein

scientific article

Infection in Health Personnel with High and Low Levels of Exposure in a Hospital Setting during the H1N1 2009 Influenza A Pandemic

scientific article

Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

scientific article

Influenza

Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

scientific article (publication date: 20 December 1998)

Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach

scientific article

Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon

scientific article published on December 2000

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

scientific article

Influenza A virus RNA polymerase has the ability to stutter at the polyadenylation site of a viral RNA template during RNA replication

scientific article

Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase

scientific article

Influenza A virus transmission bottlenecks are defined by infection route and recipient host.

scientific article

Influenza A virus-generated small RNAs regulate the switch from transcription to replication

scientific article

Influenza A viruses and PI3K: are there time, place and manner restrictions?

scientific article published on 22 June 2012

Influenza A viruses with truncated NS1 as modified live virus vaccines: pilot studies of safety and efficacy in horses

scientific article

Influenza A viruses: new research developments

scientific article published on July 11, 2011

Influenza A(H1N1)pdm09 virus infection in marine mammals in California

scientific article published on June 2013

Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility.

scientific article published on January 2013

Influenza B and C virus NEP (NS2) proteins possess nuclear export activities

scientific article

Influenza B virus NS1-truncated mutants: live-attenuated vaccine approach

scientific article

Influenza B virus reverse genetic backbones with improved growth properties in the EB66® cell line as basis for vaccine seed virus generation

scientific article published on 25 January 2018

Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR

scientific article

Influenza Virus NS1 Protein RNA-Interactome Reveals Intron Targeting

scientific article

Influenza Virus mRNA Trafficking Through Host Nuclear Speckles.

scientific article

Influenza and vaccinia viruses expressing malaria CD8+ T and B cell epitopes. Comparison of their immunogenicity and capacity to induce protective immunity.

scientific article

Influenza research database: an integrated bioinformatics resource for influenza research and surveillance.

scientific article

Influenza vaccines: a moving interdisciplinary field.

scientific article

Influenza vaccines: present and future

scientific article

Influenza vaccines: present and future

Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication.

scientific article

Influenza virus NS1- C/EBPβ gene regulatory complex inhibits RIG-I transcription

scientific article published on 21 February 2020

Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1.

scientific article published on 30 September 2005

Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.

scientific article

Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.

scientific article published on 27 September 2017

Influenza virus evades innate and adaptive immunity via the NS1 protein

scientific article published on July 2006

Influenza virus exploits tunneling nanotubes for cell-to-cell spread

scientific article

Influenza virus infection causes global RNAPII termination defects

Influenza virus receptor specificity: disease and transmission

scientific article

Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

scientific article published on 24 August 2020

Influenza virus sequence feature variant type analysis: evidence of a role for NS1 in influenza virus host range restriction.

scientific article published on 7 March 2012

Influenza virus still surprises.

scientific article

Influenza virus vaccine based on the conserved hemagglutinin stalk domain

scientific article

Influenza virus vectors

scientific article published on June 1995

Influenza-infected neutrophils within the infected lungs act as antigen presenting cells for anti-viral CD8(+) T cells

scientific article

Inhibition of Alpha/Beta Interferon Signaling by the NS4B Protein of Flaviviruses

scientific article

Inhibition of Beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3.

scientific article

Inhibition of interferon signaling by dengue virus

scientific article

Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses

scientific article

Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export

scientific article published on February 2012

Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus

scientific article

Inhibition of the alpha/beta interferon response by mouse hepatitis virus at multiple levels

scientific article published on 25 April 2007

Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus

scientific article published on September 2006

Inhibition of the ubiquitin-proteasome system affects influenza A virus infection at a postfusion step

scientific article

Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1

scientific article published on 30 September 2019

Innate immune evasion strategies of influenza viruses

scientific article

Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus

scientific article published on 29 June 2018

Insertion of a GFP reporter gene in influenza virus

scientific article published on January 2013

Integrated molecular signature of disease: analysis of influenza virus-infected macaques through functional genomics and proteomics

scientific article

Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina)

scientific article published in October 2004

Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases

scientific article

Interference of viral effector proteins with chromatin, transcription, and the epigenome

scientific article published on 29 July 2015

Interferon Antagonists of Influenza Viruses

Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing

scholarly article

Interferon priming enables cells to partially overturn the SARS coronavirus-induced block in innate immune activation

scientific article

Interferon resistance promotes oncolysis by influenza virus NS1-deletion mutants

scientific article published on May 2004

Introduction of foreign sequences into the genome of influenza A virus

scientific article published on January 1, 1994

Introduction of two prolines and removal of the polybasic cleavage site leads to optimal efficacy of a recombinant spike based SARS-CoV-2 vaccine in the mouse model

scientific article published on 17 September 2020

Introductions and early spread of SARS-CoV-2 in the New York City area

scientific article published on 29 May 2020

Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Toward a Universal Influenza Virus Vaccine: Potential Target Antigens and Critical Aspects for Vaccine Development

scientific article published on 29 June 2017

La Piedad Michoacán Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation

scientific article published on 3 November 2015

Lack of essential role of NF-kappa B p50, RelA, and cRel subunits in virus-induced type 1 IFN expression

scientific article published on June 2007

Learning from our foes: a novel vaccine concept for influenza virus

scientific article

Lessons from lipids in the fight against influenza

scientific article

Lessons learned from reconstructing the 1918 influenza pandemic.

scientific article

Live Visualization of Hemagglutinin Dynamics During Infection by Using a Novel Reporter Influenza A Virus

scientific article published on 26 June 2020

Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccine-associated enhanced respiratory disease

scientific article

Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza

scientific article

Live-attenuated influenza viruses as delivery vectors for Chlamydia vaccines

scientific article published on 23 April 2007

Loss of IL-7R and IL-15R expression is associated with disappearance of memory T cells in respiratory tract following influenza infection

scientific article published on January 2008

Loss of Sendai virus C protein leads to accumulation of RIG-I immunostimulatory defective interfering RNA.

scientific article published on 20 June 2017

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.

scientific article published on 25 January 2018

MHC class II proteins mediate cross-species entry of bat influenza viruses

scientific article published in Nature

Macaque proteome response to highly pathogenic avian influenza and 1918 reassortant influenza virus infections

scientific article

Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8(+) T Cell Responses.

scientific article published on 20 April 2016

Major histocompatibility complex class II expression and hemagglutinin subtype influence the infectivity of type A influenza virus for respiratory dendritic cells

scientific article

Mapping of the RNA promoter of Newcastle disease virus.

scientific article

Mapping of the interaction domains of the Crimean-Congo hemorrhagic fever virus nucleocapsid protein

scientific article published on 11 November 2014

Mass Cytometry Defines Virus-Specific CD4<sup>+</sup> T Cells in Influenza Vaccination

scientific article published on 11 December 2020

Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT₂A and mGlu₂ receptors in the adult offspring

scientific article

Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes.

scientific article

Mechanism of attenuation of a chimeric influenza A/B transfectant virus

scientific article published on August 1992

Mechanisms of inhibition of the host interferon alpha/beta-mediated antiviral responses by viruses

scientific article

Membrane glycoproteins of Newcastle disease virus: nucleotide sequence of the hemagglutinin-neuraminidase cloned gene and structure/function relationship of predicted amino acid sequence

scientific article published on April 2001

Memory CD8+ T cell responses expand when antigen presentation overcomes T cell self-regulation.

scientific article published in January 2008

Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.

scientific article

Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection

scientific article published on 12 November 2008

MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies

scientific article published on 11 August 2013

Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

scientific article published on 21 May 2020

Model of influenza A virus infection: dynamics of viral antagonism and innate immune response.

scientific article

Modifications of the PSAP region of the matrix protein lead to attenuation of vesicular stomatitis virus in vitro and in vivo

scientific article

Mouse STAT2 restricts early dengue virus replication

scientific article published in November 2010

Mouse dendritic cell (DC) influenza virus infectivity is much lower than that for human DCs and is hemagglutinin subtype dependent

scientific article published on 28 November 2012

Moving from Empirical to Rational Vaccine Design in the 'Omics' Era

scientific article published on 14 August 2019

Mucosal immunization with attenuated Shigella flexneri harboring an influenza hemagglutinin DNA vaccine protects mice against a lethal influenza challenge.

scientific article published in August 2004

Mucosal model of immunization against human immunodeficiency virus type 1 with a chimeric influenza virus

scientific article published in November 1995

Mucosal polyinosinic-polycytidylic acid improves protection elicited by replicating influenza vaccines via enhanced dendritic cell function and T cell immunity.

scientific article published on 23 June 2014

Multiple anti-interferon actions of the influenza A virus NS1 protein

scientific article

Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity

scientific article

Murine coronavirus delays expression of a subset of interferon-stimulated genes

scientific article published on 31 March 2010

Mutation of neuraminidase cysteine residues yields temperature-sensitive influenza viruses

scientific article

Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus.

scientific article

Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs

scientific article

Mutations to PB2 and NP proteins of an avian influenza virus combine to confer efficient growth in primary human respiratory cells.

scientific article

N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses

scientific article published on 01 June 2019

NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication

scientific article published on 7 July 2010

NS-based live attenuated H1N1 pandemic vaccines protect mice and ferrets

scientific article

NS5 of dengue virus mediates STAT2 binding and degradation

scientific article

Nairovirus Deubiquitinylating Peptidase

Negative regulation of NF-κB activity by brain-specific TRIpartite Motif protein 9.

scientific article

Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production

scientific article

Negative-strand RNA viruses: applications to biotechnology

scientific article published on May 1, 1998

Negative-strand RNA viruses: genetic engineering and applications

scientific article published on October 1996

New data on influenza virus type C confirm its peculiarities as a new genus

scientific article

New directions in vaccine research

scientific article

New prospects for the rational design of antivirals

scientific article

Newcastle Disease Virus (NDV) Oncolytic Activity in Human Glioma Tumors Is Dependent on CDKN2A-Type I IFN Gene Cluster Codeletion

scientific article published on 05 June 2020

Newcastle Disease Virus-Vectored H7 and H5 Live Vaccines Protect Chickens from Challenge with H7N9 or H5N1 Avian Influenza Viruses

scientific article published on 29 April 2015

Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate

scientific article published on 21 November 2020

Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate

scientific article published on 26 July 2020

Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins

scientific article

Newcastle disease virus V protein is a determinant of host range restriction

scientific article published on September 2003

Newcastle disease virus expressing a dendritic cell-targeted HIV gag protein induces a potent gag-specific immune response in mice

scientific article

Newcastle disease virus-based H5 influenza vaccine protects chickens from lethal challenge with a highly pathogenic H5N2 avian influenza virus

scientific article published on 4 December 2017

Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively

scientific article

Non-sterilizing, Infection-Permissive Vaccination With Inactivated Influenza Virus Vaccine Reshapes Subsequent Virus Infection-Induced Protective Heterosubtypic Immunity From Cellular to Humoral Cross-Reactive Immune Responses

scientific article published on 09 June 2020

Nonconserved nucleotides at the 3' and 5' ends of an influenza A virus RNA play an important role in viral RNA replication

scientific article published in March 1996

North American triple reassortant and Eurasian H1N1 swine influenza viruses do not readily reassort to generate a 2009 pandemic H1N1-like virus.

scientific article

Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity

scientific article

Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model

scientific article published on 07 June 2017

Novel triple-reassortant influenza viruses in pigs, Guangxi, China.

scientific article published on 16 May 2018

Novel vaccine strategies against emerging viruses

scientific article published on March 7, 2013

Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression

scientific article

OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1

scientific article published on 01 February 2020

On the inhibition mechanism of the sialidase activity from Newcastle disease virus

scientific article published in October 1991

Oncolysis of hepatic metastasis of colorectal cancer by recombinant vesicular stomatitis virus in immune-competent mice

scientific article published on September 2003

Oncolytic vesicular stomatitis virus for treatment of orthotopic hepatocellular carcinoma in immune-competent rats

scientific article published on July 2003

One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge.

scientific article

Optimization of human immunodeficiency virus gag expression by newcastle disease virus vectors for the induction of potent immune responses

scientific article

Origins of the 2009 H1N1 influenza pandemic in swine in Mexico

scientific article

Oseltamivir-resistant variants of the 2009 pandemic H1N1 influenza A virus are not attenuated in the guinea pig and ferret transmission models.

scientific article

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

scientific article

Overcoming NS1-mediated immune antagonism involves both interferon-dependent and independent mechanisms

scientific article published on 17 June 2013

PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models

scientific article

PKR is not required for interferon-gamma inhibition of VSV replication in neurons

scientific article published in January 2003

PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.

scientific article published in June 2015

Packaging of the influenza A virus genome is governed by a plastic network of RNA/protein interactions

scientific article published on 05 February 2019

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

scientific article

Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus

scientific article

Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death.

scientific article

Pandemic H1N1 influenza isolated from free-ranging Northern Elephant Seals in 2010 off the central California coast

scientific article

Pandemic influenza virus vaccines boost hemagglutinin stalk-specific antibody responses in primed adult and pediatric cohorts

scientific article published on 06 December 2019

Paramyxovirus V proteins interact with the RIG-I/TRIM25 regulatory complex and inhibit RIG-I signaling

scientific article published on 10 January 2018

Passenger Mutations Confound Phenotypes of SARM1-Deficient Mice

scientific article published on 01 April 2020

Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus.

scientific article

Pathogenicity and transmissibility of reassortant H9 influenza viruses with genes from pandemic H1N1 virus

scientific article

Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice

scientific article

Pause on avian flu transmission research

scientific article published on January 2012

Pause on avian flu transmission studies

scientific article published on 20 January 2012

Peptide-mediated interference with influenza A virus polymerase

scientific article published on 9 May 2007

Phosphorylation-mediated negative regulation of RIG-I antiviral activity

scientific article published on 13 January 2010

Physiology of cardiomyocyte injury in COVID-19

scientific article published on 13 November 2020

Pioneers of pathogenesis: past and present

scientific article published on July 23, 2011

Plasmid-only rescue of influenza A virus vaccine candidates.

scientific article

Poly-ADP Ribosyl Polymerase 1 (PARP1) Regulates Influenza A Virus Polymerase

scholarly article by Liset Westera et al published 2019 in Advances in virology

Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses

scientific article published on 17 October 2020

Pre-existing Hemagglutinin Stalk Antibodies Correlate with Protection of Lower Respiratory Symptoms in Flu-Infected Transplant Patients

scientific article published on 03 November 2020

Predicting the pathogenesis of influenza from genomic response: a step toward early diagnosis

scientific article

Preexisting human antibodies neutralize recently emerged H7N9 influenza strains.

scientific article

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

scientific article

Preparation of genetically engineered A/H5N1 and A/H7N1 pandemic vaccine viruses by reverse genetics in a mixture of Vero and chicken embryo cells.

scientific article

Prime-boost immunization schedules based on influenza virus and vaccinia virus vectors potentiate cellular immune responses against human immunodeficiency virus Env protein systemically and in the genitorectal draining lymph nodes

scientific article

Programming the magnitude and persistence of antibody responses with innate immunity

scientific article

Prostate tumor cells infected with a recombinant influenza virus expressing a truncated NS1 protein activate cytolytic CD8+ cells to recognize noninfected tumor cells

scientific article published on January 2006

Protection against influenza infection requires early recognition by inflammatory dendritic cells through C-type lectin receptor SIGN-R1

scientific article published on 29 July 2019

Protection against lethal influenza with a viral mimic

scientific article published on 29 May 2013

Protection against respiratory syncytial virus by a recombinant Newcastle disease virus vector

scientific article

Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines.

scientific article

Protective cellular immunity against influenza virus induced by plasmid inoculation of newborn mice

scientific article published in January 1998

Protective immunity to lethal challenge of the 1918 pandemic influenza virus by vaccination.

scientific article

Protein-Protein Interactions in Membranes: A Simple Practical Laboratory Class for Advanced Students of Biochemistry and Molecular Biology

scholarly article by Adolfo García-Sastre published in October 1990

Proteins of Newcastle disease virus envelope: interaction between the outer hemagglutinin-neuraminidase glycoprotein and the inner non-glycosylated matrix protein

scientific article

Proteins of newcastle disease virus envelope: interaction between the outer hemagglutinin-neuraminidase glycoprotein and the inner non-glycosylated matrix protein

Prothymosin α variants isolated from CD8+ T cells and cervicovaginal fluid suppress HIV-1 replication through type I interferon induction

scientific article published on 17 November 2014

Qualitatively different memory CD8+ T cells are generated after lymphocytic choriomeningitis virus and influenza virus infections

scientific article published on 16 July 2010

Quantitative and qualitative features of heterologous virus-vector-induced antigen-specific CD8+ T cells against Trypanosoma cruzi infection

scientific article

RIG-I Mediates an Antiviral Response to Crimean-Congo Hemorrhagic Fever Virus

scientific article

RIG-I detects mRNA of intracellular Salmonella enterica serovar Typhimurium during bacterial infection

scientific article published on April 2014

RNase L targets distinct sites in influenza A virus RNAs.

scientific article

Recent strategies to identify broadly neutralizing antibodies against influenza A virus

scientific article published on February 24, 2009

Recombinant IgA is sufficient to prevent influenza virus transmission in guinea pigs

scientific article published on 22 May 2013

Recombinant Newcastle disease virus as a vaccine vector

scientific article

Recombinant Newcastle disease virus as a vaccine vector for cancer therapy

scientific article

Recombinant Newcastle disease virus expressing H9 HA protects chickens against heterologous avian influenza H9N2 virus challenge

scientific article published on 18 April 2016

Recombinant Paramyxovirus Type 1-Avian Influenza-H7 Virus as a Vaccine for Protection of Chickens Against Influenza and Newcastle Disease

scientific article published on January 1, 2003

Recombinant influenza A viruses with enhanced levels of PB1 and PA viral protein expression

scientific article published on 7 March 2012

Recombinant influenza virus vectors

Recombinant viruses expressing a human malaria antigen can elicit potentially protective immune CD8+ responses in mice

scientific article

Reduced levels of neuraminidase of influenza A viruses correlate with attenuated phenotypes in mice

scientific article

Regulation of PURA gene transcription by three promoters generating distinctly spliced 5-prime leaders: a novel means of fine control over tissue specificity and viral signals

scientific article

Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene

scholarly article

Rescue of influenza A virus from recombinant DNA.

scientific article

Rescue of recombinant Newcastle disease virus from cDNA.

scientific article published on 11 October 2013

Residue Y161 of influenza virus hemagglutinin is involved in viral recognition of sialylated complexes from different hosts

scientific article published in February 2012

Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy

scientific article published on 23 September 2021

Reverse genetics studies on the filamentous morphology of influenza A virus

scientific article published on March 2003

SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection

scientific article published on 7 June 2013

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

scientific article published on 10 November 2020

SARS-CoV-2 infection, disease and transmission in domestic cats

scientific article published on 08 October 2020

SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses

scientific article published in February 2018

STAT2 Limits Host Species Specificity of Human Metapneumovirus

scientific article published on 04 July 2020

STAT2 signaling and dengue virus infection

scientific article

Scalable, effective, and rapid decontamination of SARS-CoV-2 contaminated N95 respirators using germicidal ultra-violet C (UVC) irradiation device

scientific article published on 06 October 2020

Sensing RNA virus infections

scientific article published in January 2007

Sequence analysis and receptor specificity of the hemagglutinin of a recent influenza H2N2 virus isolated from chicken in North America

scientific article published in February 2006

Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes

scientific article

Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model

scientific article published on 10 April 2019

Severe influenza pneumonitis in children with inherited TLR3 deficiency

scientific article published on 19 June 2019

Shedding of Viable SARS-CoV-2 after Immunosuppressive Therapy for Cancer

scientific article published on 01 December 2020

Sialidase activity in rimantadine-resistant and -sensitive influenza A viruses

scientific article published in January 1990

Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus

scientific article

Single-cell analysis of early antiviral gene expression reveals a determinant of stochastic IFNB1 expression

scientific article published on 3 November 2017

Snatch-and-Grab Inhibitors to Fight the Flu

scientific article published on 01 May 2019

Spatial-Temporal Lineage Restrictions of Embryonic p63+ Progenitors Establish Distinct Stem Cell Pools in Adult Airways.

scientific article published in March 2018

Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein

scientific article

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein

scientific article

Specific mutations in the PB2 protein of influenza A virus compensate for the lack of efficient IFN antagonism of the NS1 protein of bat influenza A-like viruses

scientific article published on 10 January 2018

Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine

scientific article published on 23 October 2020

Stimulation of human T cells by an influenza A vector expressing a CTL epitope from the HER-2/neu protooncogene results in higher numbers of antigen-specific TCRhi cells than stimulation with peptide. Divergent roles of IL-2 and IL-15

scientific article published on 01 March 2005

Strain-specific contribution of NS1-activated phosphoinositide 3-kinase signaling to influenza A virus replication and virulence

scientific article

Strong interferon-inducing capacity of a highly virulent variant of influenza A virus strain PR8 with deletions in the NS1 gene

scientific article

Structural basis for STAT2 suppression by flavivirus NS5

scientific article published on 10 August 2020

Structural basis for influenza virus NS1 protein block of mRNA nuclear export

scientific article published on 01 July 2019

Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease

scientific article

Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.

scientific article published on 11 December 2018

Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation

scientific article

Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer

scientific article

Structure of the NS3 helicase from Zika virus

scientific article

Structures of NS5 Methyltransferase from Zika Virus

scientific article (publication date: 20 September 2016)

Subcellular Localizations of RIG-I, TRIM25, and MAVS Complexes

scientific article

Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza A virus increase lethality but decrease transmission

scientific article

Suppression of the antiviral response by an influenza histone mimic

scientific article

Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer

scientific article published on May 2004

Synergistic drug combination effectively blocks Ebola virus infection

scientific article

Synthetically derived bat influenza A-like viruses reveal a cell type- but not species-specific tropism

scientific article published on 24 October 2016

Systems vaccinology informs influenza vaccine immunogenicity

scientific article

Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.

scientific article

TIPICO IX: report of the 9th interactive infectious disease workshop on infectious diseases and vaccines

scientific article published on 03 June 2019

TIPICO X: report of the 10th interactive infectious disease workshop on infectious diseases and vaccines

scientific article published on 05 August 2020

TIV Vaccination Modulates Host Responses to Influenza Virus Infection that Correlate with Protection against Bacterial Superinfection

scientific article published on 12 September 2019

TRIM25 in the Regulation of the Antiviral Innate Immunity

scientific article published on 22 September 2017

TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity

scientific article published on 12 December 2013

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

scientific article published on January 2016

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

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Taxol Increases the Amount and T Cell–Activating Ability of Self-Immune Stimulatory Multimolecular Complexes Found in Ovarian Cancer Cells

Ten Strategies of Interferon Evasion by Viruses

scientific article published on August 2017

The DBA.2 mouse is susceptible to disease following infection with a broad, but limited, range of influenza A and B viruses

scientific article published on 14 September 2011

The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors

scientific article published on February 2013

The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response

scientific article published on 04 November 2019

The Ebola virus VP35 protein functions as a type I IFN antagonist.

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The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.

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The Global Phosphorylation Landscape of SARS-CoV-2 Infection

scientific article published on 28 June 2020

The M segment of the 2009 new pandemic H1N1 influenza virus is critical for its high transmission efficiency in the guinea pig model

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The Mx1 gene protects mice against the pandemic 1918 and highly lethal human H5N1 influenza viruses.

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The N- and C-terminal domains of the NS1 protein of influenza B virus can independently inhibit IRF-3 and beta interferon promoter activation

scientific article published on November 2004

The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells

scientific article published on 29 April 2009

The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways

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The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways

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The NS1 protein: a multitasking virulence factor

scientific article published on January 2015

The NS5 Protein of the Virulent West Nile Virus NY99 Strain Is a Potent Antagonist of Type I Interferon-Mediated JAK-STAT Signaling

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The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity

scientific article published on May 2017

The Role of Interferon in Influenza Virus Tissue Tropism

scientific article published on November 1, 1998

The SARS-CoV-2 B.1.1.529 Omicron virus causes attenuated infection and disease in mice and hamsters

The cytoplasmic tail of the neuraminidase protein of influenza A virus does not play an important role in the packaging of this protein into viral envelopes

scientific article published on June 1995

The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3.

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The functional impairment of natural killer cells during influenza virus infection

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The guinea pig as a transmission model for human influenza viruses

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The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease

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The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors

scientific article published on November 2002

The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein

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The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon

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The intracellular sites of early replication and budding of SARS-coronavirus

scholarly article by Silke Stertz published in May 2007

The makings of a killer

scientific article published in September 2002

The morphology and composition of influenza A virus particles are not affected by low levels of M1 and M2 proteins in infected cells

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The neuraminidase and matrix genes of the 2009 pandemic influenza H1N1 virus cooperate functionally to facilitate efficient replication and transmissibility in pigs

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The neuraminidase of bat influenza viruses is not a neuraminidase

scientific article published on October 25, 2012

The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA.

scientific article

The origin of the PB1 segment of swine influenza A virus subtype H1N2 determines viral pathogenicity in mice

scientific article

The pause on Avian H5N1 influenza virus transmission research should be ended

scientific article

The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

scientific article published on 12 September 2016

The therapeutic effect of death: Newcastle disease virus and its antitumor potential

scientific article published on 26 July 2015

The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion

scientific article

Thogoto virus ML protein suppresses IRF3 function

scientific article published in January 2005

Three-stranded antiviral attack

scientific article published on January 2014

Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses

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Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes

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Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.

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Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models

scientific article published on 01 December 2020

Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion

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Transcription Elongation Can Affect Genome 3D Structure

scientific article published on 23 August 2018

Transcription factor redundancy ensures induction of the antiviral state

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Transcriptional role of p53 in interferon-mediated antiviral immunity.

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Transcriptome Analysis of Infected and Bystander Type 2 Alveolar Epithelial Cells during Influenza A Virus Infection Reveals Wnt Pathway Downregulation

scientific article published on 12 October 2018

Transfectant influenza A viruses are effective recombinant immunogens in the treatment of experimental cancer

scientific article published on September 1998

Transfectant influenza viruses as antigen delivery vectors

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Transfection-mediated recombination of influenza A virus

scientific article published on December 1, 1992

Transmission of influenza virus via aerosols and fomites in the guinea pig model.

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Transmission of pandemic H1N1 influenza virus and impact of prior exposure to seasonal strains or interferon treatment.

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Transmission studies resume for avian flu.

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Tumor suppressor cylindromatosis (CYLD) controls HIV transcription in an NF-κB-dependent manner

scientific article published on 23 April 2014

Turkey versus guinea pig red blood cells: hemagglutination differences alter hemagglutination inhibition responses against influenza A/H1N1.

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Type 1 interferons and the virus-host relationship: a lesson in détente .

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Type I IFN modulates innate and specific antiviral immunity

scientific article published in April 2000

Type I Interferon Induction Pathway, but Not Released Interferon, Participates in the Maturation of Dendritic Cells Induced by Negative‐Strand RNA Viruses

scientific article published on 19 March 2003

Type I interferon imposes a TSG101/ISG15 checkpoint at the Golgi for glycoprotein trafficking during influenza virus infection.

scientific article published on November 2013

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response

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Use of a mammalian internal ribosomal entry site element for expression of a foreign protein by a transfectant influenza virus.

scientific article published on October 1994

Use of reverse genetics to enhance the oncolytic properties of Newcastle disease virus

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Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine

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Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes

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Variations in the hemagglutinin of the 2009 H1N1 pandemic virus: potential for strains with altered virulence phenotype?

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Varying Inoculum Dose to Assess the Roles of the Immune Response and Target Cell Depletion by the Pathogen in Control of Acute Viral Infections

scientific article published on 03 March 2020

Vicious circle: systemic autoreactivity in Ro52/TRIM21-deficient mice

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Viral Determinants in H5N1 Influenza A Virus Enable Productive Infection of HeLa Cells

scientific article published on 31 January 2020

Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses

scientific article published on 01 December 2019

Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways

scientific article published on July 11, 2013

Viral reassortment and transmission after co-infection of pigs with classical H1N1 and triple-reassortant H3N2 swine influenza viruses

scientific article

Viral tricks to grid-lock the type I interferon system

scientific article published on 10 June 2010

Virology. Unanchored ubiquitin in virus uncoating

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Virulence determinants of pandemic influenza viruses

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Virulence-associated substitution D222G in the hemagglutinin of 2009 pandemic influenza A(H1N1) virus affects receptor binding

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Virus-induced autophagic degradation of STAT2 as a mechanism for interferon signaling blockade

scientific article published on 11 October 2019

Viruses and the type I interferon antiviral system: induction and evasion

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What can we learn from reconstructing the extinct 1918 pandemic influenza virus?

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Working Safely with H5N1 Viruses

scientific article published on March 6, 2012

Zika Virus Alters DNA Methylation of Neural Genes in an Organoid Model of the Developing Human Brain

scientific article published in January 2018

Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling

scientific article

alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s).

scientific article published on 10 August 2007

mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection

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miR-122 is more than a shield for the hepatitis C virus genome

scientific article published on January 16, 2013

p53 serves as a host antiviral factor that enhances innate and adaptive immune responses to influenza A virus.

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rVSV(M Delta 51)-M3 is an effective and safe oncolytic virus for cancer therapy

scientific article published on June 2008