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List of works by Umit Yasar

5-Fluorouracil-induced coronary spasm: may inhibition of hyperpolarization factors produced by CYP2C enzymes be the cause?

scientific article published in January 2004

A screening study on the liability of eight different female sex steroids to inhibit CYP2C9, 2C19 and 3A4 activities in human liver microsomes.

scientific article published in August 2003

Acenocoumarol sensitivity and pharmacokinetic characterization of CYP2C9 *5/*8,*8/*11,*9/*11 and VKORC1*2 in black African healthy Beninese subjects.

scientific article

Analysis of CYP2C9*5 in Caucasian, Oriental and black-African populations

scientific article

Aqueous humour penetration of moxifloxocin and gatifloxacin eye drops in different dosing regimens before phacoemulsification surgery

scientific article published on 28 October 2010

Association between ADH1C and ALDH2 polymorphisms and alcoholism in a Turkish sample.

scientific article

Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes

scientific article published on 9 April 2003

CYP1A2*1F Polymorphism Decreases Clinical Response to Clozapine in Patients with Schizophrenia

article

CYP2C9 genetic variants and losartan oxidation in a Turkish population.

scientific article

CYP2C9 genotypes and diclofenac metabolism in Spanish healthy volunteers

scientific article published on 7 May 2003

Capecitabine-induced severe hypertriglyceridemia: report of two cases

scientific article published on 3 January 2006

Decreased Activity and Genetic Polymorphisms of CYP2C19 in Behçet's Disease.

scientific article

Differential alteration of drug-metabolizing enzyme activities after cyclophosphamide/adriamycin administration in breast cancer patients

scientific article published on 01 January 2007

Disposition of a CYP2C9 phenotyping agent, losartan, is not influenced by the common 3435C > T variation of the drug transporter gene ABCB1 (MDR1).

scientific article published in August 2008

Does celecoxib inhibit agomelatine metabolism via CYP2C9 or CYP1A2?

scientific article published on 11 July 2018

Effect of atorvastatin on CYP2C9 metabolic activity as measured by the formation rate of losartan metabolite in hypercholesterolaemic patients

scientific article published on 16 March 2011

Effect of raloxifene on cerebral vasospasm following experimental subarachnoid hemorrhage in rats

scientific article published in December 2007

Effects of Genetic Polymorphisms of Cytochrome P450 Enzymes and MDR1 Transporter on Pantoprazole Metabolism and Helicobacter pylori Eradication.

scientific article

Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway

scientific article published in December 2002

Evaluation of lansoprazole as a probe for assessing cytochrome P450 2C19 activity and genotype-phenotype correlation in childhood

scientific article published on 11 November 2011

Evidence for regulation of UDP-glucuronosyltransferase (UGT) 1A1 protein expression and activity via DNA methylation in healthy human livers

scientific article published on 21 March 2013

Extracorporeal circulation systems in coronary artery bypass surgery can affect pharmacokinetics of drugs: may altered CYP-mediated liver function be a possible reason?

scientific article published on 09 May 2018

Functional effects of endothelial nitric oxide synthase genetic polymorphisms on haemorheological parameters in healthy human individuals.

scientific article

Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population.

scientific article

Hepatotoxicity due to a possible interaction between cytosine arabinoside and dipyridamole: a case report.

scientific article

Improved anti-emetic efficacy of 5-HT3 receptor antagonists in cancer patients with genetic polymorphisms of ABCB1 (MDR1) drug transporter

scientific article published on 06 November 2014

Increased risk for cerebral ischemic stroke in diabetes: genetically polymorphic CYP mediated production of neuroprotective EETs and sulfonylurea metabolism in relation with KATP channels

scientific article published on 25 September 2018

Inhibitory effect of 5-fluorouracil on cytochrome P450 2C9 activity in cancer patients

scientific article published in February 2006

Inhibitory effect of valproic acid on cytochrome P450 2C9 activity in epilepsy patients

scientific article published on 01 June 2007

Lower CYP2C9 activity in Turkish patients with Behçet's disease compared to healthy subjects: a down-regulation due to inflammation?

scientific article published on 02 August 2015

Molecular diagnosis and clinical characterization of pseudohypoparathyroidism type-Ib in a patient with mild Albright's hereditary osteodystrophy-like features, epileptic seizures, and defective renal handling of uric acid

scientific article published in July 2008

Multidrug resistance in patients undergoing resective epilepsy surgery is not associated with C3435T polymorphism in the ABCB1 (MDR1) gene

scientific article published on 23 April 2008

Ocular pharmacokinetics, safety and efficacy of intracameral moxifloxacin 0.5% solution in a rabbit model

scientific article published on 01 February 2013

Oxidation of celecoxib by polymorphic cytochrome P450 2C9 and alcohol dehydrogenase

scientific article

Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity.

scientific article published in June 2002

Penetration of ofloxacin in human aqueous and vitreous humors following oral and topical administration

scientific article published on 01 January 1998

Penetration of topical, oral, and combined administered ofloxacin into the subretinal fluid

scientific article

Pharmacogenetics of cyclophosphamide in patients with hematological malignancies

scientific article published on 23 September 2005

Pharmacokinetics of losartan and its metabolite E-3174 in relation to the CYP2C9 genotype

scientific article published in January 2002

Relationship between genetic polymorphisms of drug efflux transporter MDR1 (ABCB1) and response to losartan in hypertension patients

scientific article published in June 2016

Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation

Successful treatment of propafenone, digoxin and warfarin overdosage with plasma exchange therapy and rifampicin

scientific article published in January 2007

Tamoxifen inhibits cytochrome P450 2C9 activity in breast cancer patients

scientific article published on 01 August 2006

The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes.

scientific article

The possible role of endothelin(s) in cyclosporine A preparations--induced contraction of guinea pig isolated gallbladder strips

scientific article published on 01 October 1998

The role of pharmacogenetics of cytochrome P450s in phenytoin-induced DRESS syndrome

scientific article published on 30 June 2018

The therapeutic effects of melatonin and nimodipine in rats after cerebral cortical injury

scientific article published in January 2012

Translating biotechnology to knowledge-based innovation, peace, and development? Deploy a Science Peace Corps--an open letter to world leaders

scientific article

Two-sided action of Danshen on cytoprotective endogenous substances, epoxyeicosatrienoic acids

scientific article published on 20 June 2018

Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population.

scientific article published in January 1999

Variant alleles and genotypes of alcohol dehydrogenase 3 in a Turkish population

scientific article published on 01 May 2006

[μ-Opioid Receptor Gene (OPRM1) Polymorphisms A118G and C17T in Alcohol Dependence: A Turkish Sample].

scientific article

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