Search filters

List of works by Stephen Duffull

100 years of modelling ligand-receptor binding and response: A focus on GPCRs

scientific article published on 28 February 2020

A Bayesian Dose-Individualization Method for Warfarin ⬇️

scientific article published on January 1, 2013

A Bayesian approach for population pharmacokinetic modelling of sirolimus.

scientific article published in October 2006

A Framework for Simplification of Quantitative Systems Pharmacology Models in Clinical Pharmacology

scientific article published on 04 July 2020

A Joint Model for Vitamin K-Dependent Clotting Factors and Anticoagulation Proteins

scientific article published on 13 April 2017

A Philosophical Framework for Integrating Systems Pharmacology Models Into Pharmacometrics

scientific article

A Population Pharmacokinetic Model for 51Cr EDTA to Estimate Renal Function.

scientific article published on 9 December 2016

A Review of the Methods and Associated Mathematical Models Used in the Measurement of Fat-Free Mass.

scientific article published on 12 January 2018

A comprehensive model for the humoral coagulation network in humans.

scientific article

A d-optimal designed population pharmacokinetic study of oral itraconazole in adult cystic fibrosis patients

scientific article

A dosing regimen for immediate N-acetylcysteine treatment for acute paracetamol overdose

scientific article published on 19 August 2011

A factor VII-based method for the prediction of anticoagulant response to warfarin

scientific article published in Scientific Reports

A framework for quantifying the influence of adherence and dose individualization

scientific article published on 19 November 2015

A general empirical model for renal drug handling in pharmacokinetic analyses

scientific article

A general method to determine sampling windows for nonlinear mixed effects models with an application to population pharmacokinetic studies

scientific article published on 12 March 2012

A general model for cell death and biomarker release from injured tissues

scientific article published on 29 September 2020

A generalisation of T-optimality for discriminating between competing models with an application to pharmacokinetic studies

scientific article published on 12 October 2012

A learning-based approach for performing an in-depth literature search using MEDLINE.

scientific article published on 26 October 2010

A minimal model to describe short-term haemodynamic changes of the cardiovascular system

scientific article published on 04 September 2020

A model for venom-induced consumptive coagulopathy in snake bite

scientific article published on 12 September 2008

A model-based meta-analysis of the influence of factors that impact adherence to medications

scientific article published on 18 October 2014

A pharmacokinetic model for the glycation of albumin.

scientific article published on 21 April 2012

A pharmacokinetic simulation model for ivabradine in healthy volunteers

scientific article published on 01 January 2000

A philosophical framework for pharmacy in the 21st century guided by ethical principles

scientific article published on 28 April 2017

A population pharmacokinetic and pharmacodynamic evaluation of pralatrexate in patients with relapsed or refractory non-Hodgkin's or Hodgkin's lymphoma.

scientific article published on 27 May 2009

A population pharmacokinetic model for low-dose methotrexate and its polyglutamated metabolites in red blood cells

scientific article

A randomized pilot study of L-arginine infusion in severe falciparum malaria: preliminary safety, efficacy and pharmacokinetics

scientific article (publication date: 2013)

A randomized, controlled trial of oxycodone versus placebo in patients with postherpetic neuralgia and painful diabetic neuropathy treated with pregabalin

scientific article published on 3 December 2009

A reduction in between subject variability is not mandatory for selecting a new covariate

scientific article published on 6 July 2012

A robust design for identification of the Parasite Clearance Estimator

scientific article

A semi-mechanistic red blood cell survival model provides some insight into red blood cell destruction mechanisms.

scientific article published on 18 June 2013

A sequential Bayesian algorithm for dose individualisation of carboplatin

scientific article

A standard weight descriptor for dose adjustment in the obese patient

scientific article published in January 2004

A statistical model for red blood cell survival

scientific article published on 13 October 2010

A suggested approach to once‐daily aminoglycoside dosing ⬇️

scientific article published on June 1, 1995

A systematic review and meta-analysis of pharmacist-led fee-for-services medication review

scientific article

Activated Charcoal Decreases the Risk of QT Prolongation After Citalopram Overdose

scientific article published on 23 August 2007

Adaptive Bayesian compound designs for dose finding studies

Adaptive optimal design for bridging studies with an application to population pharmacokinetic studies

scientific article published on 14 February 2012

Adverse drug reactions

scientific article published on 01 October 1990

Aminoglycoside dosage regimens after therapeutic drug monitoring

scientific article published on 01 January 2002

Aminoglycosides in hemodialysis patients: is the current practice of post dialysis dosing appropriate?

scientific article published on 5 April 2009

Amisulpride overdose is frequently associated with QT prolongation and torsades de pointes

scientific article published in August 2010

An Evaluation of a Factor Xa-Based Clotting Time Test for Enoxaparin: A Proof-of-Concept Study.

scientific article published in January 2017

An In Silico Knockout Model for Gastrointestinal Absorption Using a Systems Pharmacology Approach - Development and Application for Ketones.

scientific article

An approach for identifiability of population pharmacokinetic-pharmacodynamic models

scientific article published on 19 June 2013

An evaluation of the operational model when applied to quantify functional selectivity

scientific article published on 19 February 2018

An extended interval dosing method for gentamicin in neonates ⬇️

scientific article published on 01 December 2001

An identifiability analysis of a parent-metabolite pharmacokinetic model for ivabradine.

scientific article published in February 2001

An intact model for quantifying functional selectivity

scientific article published on 22 February 2019

Analysis of population pharmacokinetic data using NONMEM and WinBUGS.

scientific article

Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria

scholarly article

Another case of high gentamicin clearance and volume of distribution in a patient with high output ileostomy

scientific article published on 01 April 1998

Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review

scientific article

An Extension of Janmahasatian's Fat-Free Mass Model for Universal Application Across Populations of Different Ethnicities

scientific article published on 22 March 2020

Application of Adaptive DP-optimality to Design a Pilot Study for a Clotting Time Test for Enoxaparin

scientific article

Application of pharmacokinetic-pharmacodynamic modeling in management of QT abnormalities after citalopram overdose. Reply to A. Manini

Application of pharmacokinetic-pharmacodynamic modelling in management of QT abnormalities after citalopram overdose

scientific article published on 10 May 2006

Assessing risk of a prolonged QT interval-a survey of emergency physicians

scientific article published on 18 March 2008

Assessing robustness of designs for random effects parameters for nonlinear mixed-effects models.

scientific article published on 24 October 2017

Assessment of markers of glycaemic control in diabetic patients with chronic kidney disease using continuous glucose monitoring

scientific article published in February 2012

Assessment of the relationship between methotrexate polyglutamates in red blood cells and clinical response in patients commencing methotrexate for rheumatoid arthritis

scientific article published in December 2014

Authors' Reply to Friesen: "An Extension of Janmahasatian's Fat-Free Mass Model for Universal Application Across Populations of Different Ethnicities"

scientific article published on 22 May 2020

Automated Scale Reduction of Nonlinear QSP Models With an Illustrative Application to a Bone Biology System

scientific article published on 13 August 2018

Automated proper lumping for simplification of linear physiologically based pharmacokinetic systems

scientific article published on 21 June 2019

Basic Pharmacokinetics and Pharmacodynamics, an Integrated Textbook and Computer Simulations

scientific article published in February 2012

Bayesian Hierarchical Modeling with Markov Chain Monte Carlo Methods

Between-subject variability: should high be the new normal?

scientific article published on 05 September 2014

Caution when lean body weight is used as a size descriptor for obese subjects

scientific article published in December 2002

Choosing the Allometric Exponent in Covariate Model Building

scientific article published on 01 January 2019

Clinical decision-making: An essential skill for 21st century pharmacy practice

scientific article published on 07 August 2018

Clinical pharmacokinetics and dose optimisation of carboplatin.

scientific article

Comparison of intracellular methotrexate kinetics in red blood cells with the kinetics in other cell types

scientific article published in March 2014

Comparison of robust criteria for D-optimal designs

scientific article published in January 2012

Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers

scientific article published in October 2009

Comparison of two Bayesian approaches to dose-individualization for once-daily aminoglycoside regimens

scientific article published on February 1997

Compound optimal design criteria for nonlinear models

scientific article published in January 2008

Concepts for Critical Appraisal of an Original Research Paper

article

Correction: Increased Asymmetric Dimethylarginine in Severe Falciparum Malaria: Association with Impaired Nitric Oxide Bioavailability and Fatal Outcome.

scientific article published on 11 May 2010

Current enoxaparin dosing guidelines have dubious credibility.

scientific article published on 30 April 2010

Dabigatran: rational dose individualisation and monitoring guidance is needed

scientific article published on June 29, 2012

Defining Target Vancomycin Trough Concentrations for Treating Staphylococcus aureus Infection in Infants Aged 0 to 90 Days

scientific article published on 10 June 2019

Design Of Clinical Pharmacology Trials ⬇️

scientific article published on 01 November 2001

Design of experiments for bivariate binary responses modelled by Copula functions

article

Design of pharmacokinetic studies for latent covariates

scientific article published on 10 December 2011

Designs to balance cost and success rate for an early phase clinical study

scientific article published on 23 February 2016

Deterministic identifiability of population pharmacokinetic and pharmacokinetic-pharmacodynamic models

scientific article published on 13 June 2017

Development and evaluation of a prototype of a novel clotting time test to monitor enoxaparin

scientific article published on 6 August 2011

Development and implementation of the population Fisher information matrix for the evaluation of population pharmacokinetic designs

scientific article published in May 2001

Development of a Parsimonious Design for Optimal Classification of Exclusive Breastfeeding

scientific article published on 03 July 2019

Development of a Semimechanistic Model to Describe the Pharmacokinetics of Gentamicin in Patients Receiving Hemodialysis

article

Development of a bayesian forecasting method for warfarin dose individualization

scientific article published on 8 February 2011

Development of a dosage strategy in patients receiving enoxaparin by continuous intravenous infusion using modelling and simulation

scientific article published in August 2006

Development of a dosing strategy for enoxaparin in obese patients

scientific article published in July 2003

Development of a general method of limited sampling for the determination of AUC for a drug that displays two-compartment pharmacokinetics

article

Development of a nonlinear hierarchical model to describe the disposition of deuterium in mother-infant pairs to assess exclusive breastfeeding practice

scientific article published on 14 November 2018

Development of a population pharmacokinetic-pharmacodynamic model of a single bolus dose of unfractionated heparin in paediatric patients

scientific article published on 11 March 2016

Development of a sequential linked pharmacokinetic and pharmacodynamic simulation model for ivabradine in healthy volunteers

article

Development of a sufficient design for estimation of fluconazole pharmacokinetics in people with HIV infection.

scientific article published on 28 June 2008

Dose- and exposure-response to ketamine in depression

scientific article published on 8 April 2011

Dosing in obesity: a simple solution to a big problem.

scientific article published in November 2007

Dosing of gentamicin in patients with end-stage renal disease receiving hemodialysis

scientific article published in November 2006

Effect of Australian elapid venoms on blood coagulation: Australian Snakebite Project (ASP-17).

scientific article published on 11 November 2012

Efficacies of different vancomycin dosing regimens against Staphylococcus aureus determined with a dynamic in vitro model.

scientific article published on October 1994

Enhanced gentamicin clearance associated with ileostomy fluid loss

scientific article published on 01 April 1997

Estimating risk from underpowered, but statistically significant, studies: was APPROVe on TARGET? ⬇️

scientific article published on December 12, 2010

Estimation of pharmacokinetic parameters from non-compartmental variables using Microsoft Excel

scientific article

Evaluating Lean Liver Volume as a Potential Scaler for in vitro-in vivo Extrapolation of Drug Clearance in Obesity using the model drug antipyrine

scientific article published on 14 May 2020

Evaluating the Relationship Between Lean Liver Volume and Fat-Free Mass

scientific article published on 01 April 2020

Evaluation of Approaches to Deal with Low-Frequency Nuisance Covariates in Population Pharmacokinetic Analyses.

scientific article

Evaluation of Assumptions Underpinning Pharmacometric Models

scientific article published on 05 August 2019

Evaluation of designs for renal drug studies based on the EMA and FDA guidelines for drugs that are predominantly secreted

scientific article published on 28 August 2020

Evaluation of graphical diagnostics for assessing goodness of fit of logistic regression models

scientific article published on 14 December 2010

Evaluation of red blood cell labelling methods based on a statistical model for red blood cell survival.

scientific article

Evaluation of the Pre-Posterior Distribution of Optimized Sampling Times for the Design of Pharmacokinetic Studies

scientific article published on 01 January 2012

Evaluation of the profiles of CB1 cannabinoid receptor signalling bias using joint kinetic modelling

scientific article published on 15 April 2020

Evidence for the changing regimens of acetylcysteine

scientific article published on 19 September 2015

Experience of once-daily aminoglycoside dosing using a target area under the concentration-time curve

scientific article published on 01 June 1995

Experience with heparin dosing at Christchurch Hospital

scientific article published on June 26, 1998

Exploring inductive linearization for pharmacokinetic-pharmacodynamic systems of nonlinear ordinary differential equations.

scientific article published on 26 May 2017

Exposure response - getting the dose right

scientific article published on 01 July 2009

Failure of antivenom to improve recovery in Australian snakebite coagulopathy.

scientific article published on July 2009

Fluoxetine distribution in human milk

scientific article published on 01 November 1996

Free mycophenolic acid should be monitored in renal transplant recipients with hypoalbuminemia.

scientific article

GFR may not accurately predict aspects of proximal tubule drug handling

scientific article published on 20 August 2014

General practitioners' perceptions of pharmacists' new services in New Zealand

scientific article published on 23 February 2012

General practitioners' views of pharmacists' current and potential contributions to medication review and prescribing in New Zealand

scientific article published on September 2013

How vancomycin is used in Australasia - A survey

scientific article published on 01 December 1993

Idiosyncratic drug-induced haematological abnormalities. Incidence, pathogenesis, management and avoidance.

scientific article

Impact of anticholinergic discontinuation on cognitive outcomes in older people: a systematic review.

scientific article published on March 2014

Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria

scientific article

In reply

Incidence and risk factors of major bleeding following major orthopaedic surgery with fondaparinux thromboprophylaxis. A time-to-event analysis

scientific article published on 14 July 2018

Increased asymmetric dimethylarginine in severe falciparum malaria: association with impaired nitric oxide bioavailability and fatal outcome

scientific article

Individualized compared with conventional dosing of enoxaparin

scientific article published on 10 October 2007

Individualized dosing of enoxaparin for subjects with renal impairment is superior to conventional dosing at achieving therapeutic concentrations

scientific article published in August 2010

Influence of Genotype on Warfarin Maintenance Dose Predictions Produced Using a Bayesian Dose Individualization Tool.

scientific article published on December 2016

Interaction between amiodarone and phenytoin

scientific article published on 01 February 1991

Interpreting population pharmacokinetic-pharmacodynamic analyses - a clinical viewpoint.

scientific article

Introduction to Pharmacokinetics in Clinical Toxicology ⬇️

scientific article published on January 1, 2012

Investigating myotoxicity following Australian red-bellied black snake (Pseudechis porphyriacus) envenomation

scientific article published on 10 September 2021

Is the dose of dabigatran really more predictable than warfarin? ⬇️

scientific article published on December 1, 2013

Is the ideal anticoagulant a myth? ⬇️

scientific article published on 01 May 2012

Kinetic-pharmacodynamic model for drugs with non-linear elimination: Parameterisation matters

scientific article published on 10 January 2020

Lack of effect of tart cherry concentrate dose on serum urate in people with gout

scientific article published on 31 December 2019

Lean body mass normalizes the effect of obesity on renal function.

scientific article published on 15 February 2008

Measuring the Development of Therapeutic-Decision-Making Skills by Practicing Pharmacists Undertaking a University-Based Postgraduate Clinical Qualification at Distance

scientific article published on 11 May 2020

Methanol and ethylene glycol acute poisonings - predictors of mortality

scientific article

Methods and software tools for design evaluation in population pharmacokinetics-pharmacodynamics studies.

scientific article published on January 2015

Methods for Predicting Warfarin Dose Requirements.

scientific article published on August 2015

Methods of robust design of nonlinear models with an application to pharmacokinetics

scientific article published in July 2010

Methods to Account for Inaccuracies in the Dosing History When Performing Population Pharmacokinetic Analysis

scientific article published on 08 July 2008

Model-free and kinetic modelling approaches for characterising non-equilibrium pharmacological pathway activity: Internalisation of cannabinoid CB1 receptors

scientific article published on 21 May 2019

Modeling and stimulation for clinical trial design involving a categorical response: a phase II case study with naratriptan

scientific article published on August 2001

Modeling red blood cell survival data

scientific article

Modelling the occurrence and severity of enoxaparin-induced bleeding and bruising events

scientific article

Myocardial infarction and type II diabetes--preferential treatment for high risk patients?

scientific article published in October 2002

Once-daily aminoglycoside therapy: potential ototoxicity

scientific article published on 01 April 1997

Optimal Design of Pharmacokinetic–Pharmacodynamic Studies

Optimal crossover designs for logistic regression models in pharmacodynamics

scientific article published in January 2006

Optimal design criteria for discrimination and estimation in nonlinear models

scientific article published in January 2009

Optimal design for model discrimination and parameter estimation for itraconazole population pharmacokinetics in cystic fibrosis patients

scientific article published in August 2005

Optimal design of a population pharmacodynamic experiment for ivabradine

scientific article

Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria

scientific article

Optimal designs for population pharmacokinetic studies of the partner drugs co-administered with artemisinin derivatives in patients with uncomplicated falciparum malaria

scientific article

Optimal designs for studying bioimpedance

scientific article published on 31 October 2007

Optimal dosing of enoxaparin in overweight and obese children

Parameterisation affects identifiability of population models.

scientific article published on 31 December 2013

Paroxetine in human milk

scientific article

Pharmacists' performance of clinical interventions during adherence support medication reviews

scientific article published on 17 May 2013

Pharmacokinetic considerations on the repurposing of ivermectin for treatment of COVID-19

scientific article published on 17 July 2020

Pharmacokinetic software for the health sciences: choosing the right package for teaching purposes

scientific article

Pharmacokinetic-Pharmacodynamic Model for the Effect of l-Arginine on Endothelial Function in Patients with Moderately Severe Falciparum Malaria

scientific article published on 19 October 2015

Pharmacokinetic-pharmacodynamic modelling of QT interval prolongation following citalopram overdoses

scientific article published in February 2006

Pharmacokinetics and efficacy of rectal versus oral sustained-release morphine in cancer patients

scientific article

Pharmacokinetics of L-arginine in adults with moderately severe malaria

scientific article published on 06 October 2008

Pharmacokinetics of Snake Venom.

scientific article published on 7 February 2018

Pharmacokinetics of gentamicin in 957 patients with varying renal function dosed once daily.

scientific article

Pharmacokinetics of quetiapine in overdose and the effect of activated charcoal.

scientific article published on 4 April 2007

Pharmacometrics and Systems Pharmacology 2030

scientific article published on 23 November 2019

Pharmacometrics in Australasia-Twenty Years of Population Approach Group of Australia and New Zealand

scientific article published on 16 September 2019

Population analysis of once‐daily dosing of gentamicin in patients with neutropenia ⬇️

scientific article published on June 1, 1998

Population pharmacokinetic analysis of mycophenolic acid in renal transplant recipients following oral administration of mycophenolate mofetil

scientific article published in August 2003

Population pharmacokinetics and pharmacodynamics of escitalopram in overdose and the effect of activated charcoal

scientific article

Population pharmacokinetics of <i>Pseudechis porphyriacus</i> (red-bellied black snake) venom in snakebite patients

scientific article published on 09 April 2021

Population pharmacokinetics of intramuscular droperidol in acutely agitated patients

scientific article

Population pharmacokinetics of ivermectin for the treatment of scabies in Indigenous Australian children

scientific article published on 07 December 2020

Population pharmacokinetics of melphalan in patients with multiple myeloma undergoing high dose therapy.

scientific article

Population pharmacokinetics of mycophenolic acid during the first week after renal transplantation

scientific article published on 28 July 2005

Potential Issues With Virtual Populations When Applied to Nonlinear Quantitative Systems Pharmacology Models

scientific article published on 24 September 2020

Predicting allopurinol response in patients with gout

scientific article published on 9 October 2015

Predicting the requirement for N-acetylcysteine in paracetamol poisoning from reported dose

scientific article published on 22 August 2013

Prediction of Fat-Free Mass in Children

scientific article published on 5 May 2015

Prediction of drug loss from PVC infusion bags

scientific article published in May 1991

Prediction of torsade de pointes from the QT interval: analysis of a case series of amisulpride overdoses

scientific article (publication date: August 2011)

Promethazine overdose: clinical effects, predicting delirium and the effect of charcoal

scientific article published on 28 November 2008

Prospective evaluation of a D-optimal designed population pharmacokinetic study.

scientific article published in April 2003

Prospective evaluation of a model for the prediction of milk:plasma drug concentrations from physicochemical characteristics

scientific article

Quantification of lean bodyweight

scientific article published in January 2005

Quantification of the Forgiveness of Drugs to Imperfect Adherence

scientific article published on 4 March 2015

Quetiapine overdose: predicting intubation, duration of ventilation, cardiac monitoring and the effect of activated charcoal.

scientific article published in July 2009

Recovery of endothelial function in severe falciparum malaria: relationship with improvement in plasma L-arginine and blood lactate concentrations

scientific article

Red blood cell survival in long-term dialysis patients.

scientific article published on 29 June 2011

Relationship of cell-free hemoglobin to impaired endothelial nitric oxide bioavailability and perfusion in severe falciparum malaria

scientific article

Relationships between sirolimus dosing, concentration and outcomes in renal transplant recipients

scientific article published in November 2005

Relationships of tacrolimus pharmacokinetic measures and adverse outcomes in stable adult liver transplant recipients

scientific article published in February 2006

Reply to Dr. Mégarbane et al. regarding “Pharmacokinetic/pharmacodynamic modelling of cardiac toxicity in venlafaxine overdose”

article

Reply to the editor of Journal of Pharmacokinetics and Pharmacodynamics

Response to “Influence of Lean Body Weight on Anticancer Drug Clearance”

Retrospective examination of selected outcomes of Medicines Use Review (MUR) services in New Zealand.

scientific article published on 15 March 2014

Reusing Smaller Versions of Large Models: A Case Example of Reuse of a Simplified Bone Model

scientific article published on 27 August 2019

Revisiting the Pharmacology of Unfractionated Heparin

scientific article published on 01 August 2019

Routine plasma anti-Xa monitoring is required for low-molecular-weight heparins.

scientific article

Safety profile of L-arginine infusion in moderately severe falciparum malaria

scientific article

Sampling times for monitoring tacrolimus in stable adult liver transplant recipients.

scientific article published in December 2004

Scale reduction of a systems coagulation model with an application to modeling pharmacokinetic-pharmacodynamic data

scientific article

Selection and Qualification of Simplified QSP Models When Using Model Order Reduction Techniques.

scientific article published on 27 November 2017

SimPharm: How pharmacy students made meaning of a clinical case differently in paper- and simulation-based workshops

article

Simplification of a pharmacokinetic model for red blood cell methotrexate disposition

scientific article published on 26 September 2015

Simultaneous versus sequential optimal design for pharmacokinetic-pharmacodynamic models with FO and FOCE considerations

scientific article published on 18 February 2009

Single or multiple daily doses of aminoglycosides. Exposure to aminoglycosides should be monitored during treatment

scientific article published in August 1996

Some Considerations on the Design of Population Pharmacokinetic Studies

scientific article published on 01 August 2005

Students' perceptions of playing a serious game intended to enhance therapeutic decision-making in a pharmacy curriculum

scientific article published on 12 June 2020

Studying drugs in human milk: time to unify the approach.

scientific article

Sulfate conjugation may be the key to hepatotoxicity in paracetamol overdose

scientific article published on 11 November 2020

Systematic comparison of the population pharmacokinetics and pharmacodynamics of piperacillin in cystic fibrosis patients and healthy volunteers

scientific article published on 7 May 2007

Terfenadine ineffective in the prophylaxis of exercise-induced pruritus

scientific article published on 01 April 1992

The Influence of Haemostatic System Maturation on the Dose-Response Relationship of Unfractionated Heparin

scientific article published on 31 October 2020

The Influence of Patient Characteristics on Anticholinergic Events in Older People

scientific article published on September 2015

The Influence of the Different Disposition Characteristics of Snake Toxins on the Pharmacokinetics of Snake Venom

scientific article published on 16 March 2020

The Population Pharmacokinetics of D-β-hydroxybutyrate Following Administration of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate.

scientific article published on 18 February 2016

The effect of body weight on dalteparin pharmacokinetics. A preliminary study

scientific article published in July 2000

The effect of decontamination procedures on the pharmacodynamics of venlafaxine in overdose

scientific article

The effect of decontamination procedures on the pharmacokinetics of venlafaxine in overdose.

scientific article published on 15 July 2009

The influence of dosing time, variable compliance and circadian low-density lipoprotein production on the effect of simvastatin: simulations from a pharmacokinetic-pharmacodynamic model.

scientific article

The intact nephron hypothesis as a model for renal drug handling

article

The pharmacokinetics of meropenem and piperacillin-tazobactam during sustained low efficiency haemodiafiltration (SLED-HDF)

scientific article published on 09 December 2019

The pharmacokinetics of methanol in the presence of ethanol: a case study

scientific article published in April 2011

The pharmacokinetics of sertraline in overdose and the effect of activated charcoal.

scientific article

The pharmacometrician's dilemma: the tension between mechanistic and empirical approaches in mathematical modelling and simulation - a continuation of the age-old dispute between rationalism and empiricism?

scientific article published on 12 June 2016

The population pharmacokinetics of allopurinol and oxypurinol in patients with gout

scientific article published on 10 March 2013

The population pharmacokinetics of citalopram after deliberate self-poisoning: a Bayesian approach

scientific article published in August 2005

The propagation of between-subject variability from dose to response

scientific article published on 19 December 2020

The relevance of gluten in pharmaceutical products

scientific article published on 01 August 1993

The time course of drug effects.

scientific article published on July 2009

The use of a change in gentamicin clearance as an early predictor of gentamicin-induced nephrotoxicity

scientific article published in October 2003

The use of simulated annealing for finding optimal population designs

scientific article published in July 2002

Therapeutic decision-making in primary care pharmacy practice

scientific article published on 10 April 2020

The Association between Metformin Therapy and Lactic Acidosis

scientific article published on 01 December 2019

Towards optimal design of anti-malarial pharmacokinetic studies

scientific article published on 06 August 2009

Twice- and Thrice-daily Cephalexin Dosing for Staphylococcus aureus Infections in Children

scientific article published on 01 June 2020

Understanding probability and exposure in paracetamol overdose risk assessment

scientific article published on 5 November 2013

Understanding the association between metformin plasma concentrations and lactate

scientific article published on 09 June 2020

Understanding the process of clinical judgement for pharmacists when making clinical decisions

scientific article published on 10 August 2018

Understanding the time course of pharmacological effect: a PKPD approach

scientific article published on June 2011

Using Disease Progression Models as a Tool to Detect Drug Effect

scientific article published on 16 May 2007

Vancomycin toxicity. What is the evidence for dose dependency?

scientific article published on January 1994

Warfarin Dosing Algorithms Underpredict Dose Requirements in Patients Requiring ≥7 mg Daily: A Systematic Review and Meta-analysis

scientific article

What do we learn from repeated population analyses?

scientific article published on January 2015

What free services do pharmacists offer? Investigating the provision of unfunded pharmacy services in community pharmacies

scientific article published on 11 May 2020

What is the Best Way to Deliver Therapeutics and Who decides? ⬇️

scientific article published on 01 July 2013

What is the best size descriptor to use for pharmacokinetic studies in the obese?

scientific article published in August 2004

When is research clinical advice? Interpreting an exploratory study of paracetamol overdose.

scientific article

Why monitor peak vancomycin concentrations?

Paulina is supported by:

About Paulina

Help