Search filters

List of works by Anthony J Day

A bug in CUB's clothing: similarity between clostridial CBMs and complement CUBs.

scientific article

A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function

scientific article published on 08 January 2014

Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation

scientific article published on 21 January 2016

Age-dependent changes in heparan sulfate in human Bruch's membrane: implications for age-related macular degeneration

scientific article published on 29 July 2014

Age-related macular degeneration and the role of the complement system.

scientific article published on 21 March 2015

Analysis of CD44-hyaluronan interactions in an artificial membrane system: insights into the distinct binding properties of high and low molecular weight hyaluronan

scientific article published on 27 July 2010

Articular cartilage proteoglycans as boundary lubricants: structure and frictional interaction of surface-attached hyaluronan and hyaluronan--aggrecan complexes.

scientific article

Associative and structural properties of the region of complement factor H encompassing the Tyr402His disease-related polymorphism and its interactions with heparin

scientific article

Biotinyl analogues of amylin as biologically active probes for amylin/CGRP receptor recognition

scientific article published on 01 January 1992

C-reactive protein and pentraxin-3 binding of factor H-like protein 1 differs from complement factor H: implications for retinal inflammation

scientific article

Characterization of a functional hyaluronan-binding domain from the human CD44 molecule expressed in Escherichia coli

scientific article published on 01 December 1998

Characterization of complexes formed between TSG-6 and inter-alpha-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan.

scientific article

Characterization of hyaluronan and TSG-6 in skin scarring: differential distribution in keloid scars, normal scars and unscarred skin.

scientific article

Characterization of the interaction between tumor necrosis factor-stimulated gene-6 and heparin: implications for the inhibition of plasmin in extracellular matrix microenvironments.

scientific article published on 24 May 2005

Characterization of xenopus laevis complement factor I structure—conservation of modular structure except for an unusual insert not present in human factor I ⬇️

scientific article published on October 1, 1993

Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathology.

scientific article published on October 2010

Complementing the Sugar Code: Role of GAGs and Sialic Acid in Complement Regulation

scientific article

Constitutive expression of inter-α-inhibitor (IαI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex.

scientific article published on 20 February 2012

Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6.

scientific article

Decreased expression of tumor necrosis factor-alpha-stimulated gene 6 in cumulus cells of the cyclooxygenase-2 and EP2 null mice

scientific article published in March 2003

Determining the molecular basis for the pH-dependent interaction between the link module of human TSG-6 and hyaluronan.

scientific article published on 15 February 2007

Development of a microtiter plate-based glycosaminoglycan array for the investigation of glycosaminoglycan-protein interactions.

scientific article

Disrupted function of tumor necrosis factor-alpha-stimulated gene 6 blocks cumulus cell-oocyte complex expansion

scientific article published on 17 July 2003

Experimental evidence for all-or-none cooperative interactions between the G1-domain of versican and multivalent hyaluronan oligosaccharides.

scientific article published on 26 September 2005

Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6-8.

scientific article published on 5 May 2007

His-384 Allotypic Variant of Factor H Associated with Age-related Macular Degeneration Has Different Heparin Binding Properties from the Non-disease-associated Form

scientific article published in Journal of Biological Chemistry

Homodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic Endothelium

scientific article

Hyaluronan and Hyaluronan Binding Proteins Are Normal Components of Mouse Pancreatic Islets and Are Differentially Expressed by Islet Endocrine Cell Types ⬇️

scientific article published on July 21, 2012

Hyaluronan and homeostasis: a balancing act.

scientific article

Hyaluronan and hyaluronan-binding proteins accumulate in both human type 1 diabetic islets and lymphoid tissues and associate with inflammatory cells in insulitis.

scientific article

Hyaluronan binding properties of a CD44 chimera containing the link module of TSG-6.

scientific article

Hyaluronan binding to link module of TSG-6 and to G1 domain of aggrecan is differently regulated by pH.

scientific article

Hyaluronan cross-linking: a protective mechanism in inflammation?

scientific article

Hyaluronan fragments/CD44 mediate oxidative stress-induced MUC5B up-regulation in airway epithelium.

scientific article published on 28 August 2008

Hyaluronan, TSG-6, and inter-α-inhibitor in periprosthetic breast capsules: reduced levels of free hyaluronan and TSG-6 expression in contracted capsules.

scientific article

Identification of CD44 residues important for hyaluronan binding and delineation of the binding site

scientific article published on 01 January 1998

Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina.

scientific article

Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice

scientific article published in May 2003

Implication of the oligomeric state of the N-terminal PTX3 domain in cumulus matrix assembly

scientific article

Incorporation of pentraxin 3 into hyaluronan matrices is tightly regulated and promotes matrix cross-linking ⬇️

scientific article

Induction of the hyaluronic acid-binding protein, tumor necrosis factor-stimulated gene-6, in cervical smooth muscle cells by tumor necrosis factor-alpha and prostaglandin E(2).

scientific article published on April 2002

Inhibitory effects of TSG-6 Link module on leukocyte-endothelial cell interactions in vitro and in vivo.

scientific article published on October 2004

Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation

scientific article published on 06 March 2020

Inter-α-inhibitor impairs TSG-6-induced hyaluronan cross-linking

scientific article published on 04 September 2013

Isolation and purification of versican and analysis of versican proteolysis.

scientific article

Localization and characterization of the hyaluronan-binding site on the link module from human TSG-6.

scientific article published on July 2000

Long pentraxin 3/tumor necrosis factor-stimulated gene-6 interaction: a biological rheostat for fibroblast growth factor 2-mediated angiogenesis

scientific journal article

Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera

scientific article

Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix. ⬇️

scientific article

Method for quantitative refolding of the link module from human TSG-6.

scientific article

Molecular analysis of the cumulus matrix: insights from mice with O-glycan-deficient oocytes.

scientific article

New strategies for cartilage regeneration exploiting selected glycosaminoglycans to enhance cell fate determination

scientific article published on 01 June 2014

Normal and shear interactions between hyaluronan-aggrecan complexes mimicking possible boundary lubricants in articular cartilage in synovial joints

scientific article published on November 2012

Nuclear Magnetic Resonance Insight into the Multiple Glycosaminoglycan Binding Modes of the Link Module from Human TSG-6

scientific article (publication date: 19 January 2016)

Overexpression, purification, and refolding of link module from human TSG-6 in Escherichia coli: effect of temperature, media, and mutagenesis on lysine misincorporation at arginine AGA codons.

scientific article

Overlapping sites on the Link module of human TSG‐6 mediate binding to hyaluronan and chondroitin‐4‐sulphate ⬇️

scientific article published on June 30, 1997

PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization

scientific article

Partial characterization of human complement factor H by protein and cDNA sequencing: homology with other complement and non-complement proteins

scientific article published on 01 January 1986

Plasticity of the TSG-6 HA-binding loop and mobility in the TSG-6-HA complex revealed by NMR and X-ray crystallography

scientific article

Secondary structure of a complement control protein module by two-dimensional 1H NMR

scientific article published on 01 January 1991

Selective inhibition of ADAMTS-1, -4 and -5 by catechin gallate esters.

scientific article published on June 2003

Sequence polymorphism of human complement factor H

scientific article published on 01 January 1988

Shiga toxin activates complement and binds factor H: evidence for an active role of complement in hemolytic uremic syndrome

scientific article (publication date: 15 May 2009)

Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation

scientific article published on 29 October 2008

Specificity of the tumor necrosis factor-induced protein 6-mediated heavy chain transfer from inter-alpha-trypsin inhibitor to hyaluronan: implications for the assembly of the cumulus extracellular matrix

scientific article

Structural basis for complement factor H linked age-related macular degeneration

scientific article

Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organization

scientific article published on 25 January 2008

Structure and specificity of complement receptors.

scientific article

Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44.

scientific article published in February 2004

Structure-function relationships of the complement components

scientific article published on 01 June 1989

Sulfation of the bikunin chondroitin sulfate chain determines heavy chain·hyaluronan complex formation

scientific article published on 25 June 2013

Superficial zone chondrocytes in normal and osteoarthritic human articular cartilages synthesize novel truncated forms of inter-alpha-trypsin inhibitor heavy chains which are attached to a chondroitin sulfate proteoglycan other than bikunin.

scientific article published on 3 June 2008

Supramolecular synergy in the boundary lubrication of synovial joints.

scientific article published on 10 March 2015

Synthesis of tumor necrosis factor alpha-induced protein 6 in porcine preovulatory follicles: a study with A38 antibody

scientific article published on 6 February 2008

TNFalpha-stimulated gene product (TSG-6) and its binding protein, IalphaI, in the human intervertebral disc: new molecules for the disc.

scientific article

TSG-6 binds via its CUB_C domain to the cell-binding domain of fibronectin and increases fibronectin matrix assembly

scientific journal article

TSG-6 inhibits neutrophil migration via direct interaction with the chemokine CXCL8

scientific journal article

TSG-6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin

scientific article published on 30 March 2011

TSG-6 modulates the interaction between hyaluronan and cell surface CD44.

scientific article published on April 2004

TSG-6 potentiates the antitissue kallikrein activity of inter-alpha-inhibitor through bikunin release.

scientific article published on 27 July 2006

TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation

scientific article published on 26 June 2008

TSG-6: a multifunctional protein associated with inflammation ⬇️

scientific article published on May 15, 2003

TSG‐6 interacts with hyaluronan and aggrecan in a pH‐dependent manner via a common functional element: implications for its regulation in inflamed cartilage ⬇️

scientific article published on May 29, 1998

The C1q and collectin binding site within C1q receptor (cell surface calreticulin)

scientific article

The N-terminal module of thrombospondin-1 interacts with the link domain of TSG-6 and enhances its covalent association with the heavy chains of inter-alpha-trypsin inhibitor.

scientific article

The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity ⬇️

scientific article published on October 15, 1997

The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2

scientific journal article

The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells

scientific article published on 9 February 2007

The inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers

scientific article published on 19 May 2011

The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner.

scientific article

The microvascular extracellular matrix in brains with Alzheimer's disease neuropathologic change (ADNC) and cerebral amyloid angiopathy (CAA)

scientific article published on 29 September 2020

The proteoglycan glycomatrix: a sugar microenvironment essential for complement regulation.

scientific article

The role of complement in age-related macular degeneration: heparan sulphate, a ZIP code for complement factor H?

scientific article published on 07 December 2013

Three-dimensional structure of a complement control protein module in solution ⬇️

scientific article published on June 20, 1991

Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions

scientific article

Towards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: insights into other members of the link module superfamily.

scientific article

Up-regulation and differential expression of the hyaluronan-binding protein TSG-6 in cartilage and synovium in rheumatoid arthritis and osteoarthritis

scientific article published on 01 January 2001

Use of 15N-NMR to resolve molecular details in isotopically-enriched carbohydrates: sequence-specific observations in hyaluronan oligomers up to decasaccharides.

scientific article

Using Molecular Dynamics Simulations To Provide New Insights into Protein Structure on the Nanosecond Timescale:  Comparison with Experimental Data and Biological Inferences for the Hyaluronan-Binding Link Module of TSG-6.

scientific article

Versican-thrombospondin-1 binding in vitro and colocalization in microfibrils induced by inflammation on vascular smooth muscle cells.

scientific article

Paulina is supported by:

About Paulina

Help