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List of works by Alex Gutterres Taranto

21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na,K-ATPase and epithelial tight junctions

scientific article

A critical view on antimalarial endoperoxide QSAR studies.

scientific article published on June 2012

Antimalarial activity of 4-metoxychalcones: docking studies as falcipain/plasmepsin inhibitors, ADMET and lipophilic efficiency analysis to identify a putative oral lead candidate.

scientific article published on 10 December 2013

Brazilian malaria molecular targets (BraMMT): selected receptors for virtual high-throughput screening experiments

article

Caffeoylquinic acids from antiplasmodial active extract of Xanthium cavanillesii fruits and their molecular modelling studies

scientific article published on 13 August 2016

Comparative modeling of DNA and RNA polymerases from Moniliophthora perniciosa mitochondrial plasmid.

scientific article published on 10 September 2009

Cytotoxic and cytostatic effects of digitoxigenin monodigitoxoside (DGX) in human lung cancer cells and its link to Na,K-ATPase.

scientific article published in November 2017

Cytotoxic effects of the cardenolide convallatoxin and its Na,K-ATPase regulation.

scientific article

Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+-ATPase inhibition

scientific article published on 11 August 2018

DFT study of the reductive decomposition of artemisinin

scientific article published on 2 November 2005

Dengue outbreaks in Divinopolis, south-eastern Brazil and the geographic and climatic distribution of Aedes albopictus and Aedes aegypti in 2011-2012.

scientific article published on 20 October 2014

Detection of the antiviral activity of epicatechin isolated from Salacia crassifolia (Celastraceae) against Mayaro virus based on protein C homology modelling and virtual screening.

scientific article

Docking, QM/MM, and molecular dynamics simulations of the hexose transporter from Plasmodium falciparum (PfHT).

scientific article published in April 2016

Docking-based virtual screening of Brazilian natural compounds using the OOMT as the pharmacological target database.

scientific article published on 11 March 2017

Epitopes rationally selected through computational analyses induce T-cell proliferation in mice and are recognized by serum from individuals infected with Schistosoma mansoni.

scientific article published on 3 April 2017

Evidence for the involvement of spinal cord-inhibitory and cytokines-modulatory mechanisms in the anti-hyperalgesic effect of hecogenin acetate, a steroidal sapogenin-acetylated, in mice.

scientific article

Homology modelling of pyrophosphosrylase, enzyme involved in chitin pathway of Moniliophthora perniciosa

scientific article published in January 2009

Identification and characterization of a class III chitin synthase gene of Moniliophthora perniciosa, the fungus that causes witches' broom disease of cacao.

scientific article published in August 2009

Identification of a vaccine against schistosomiasis using bioinformatics and molecular modeling tools.

scientific article published on 20 August 2013

Identification of novel antiplasmodial compound by hierarquical virtual screening and in vitro assays

scientific article published on 04 May 2020

In silico studies of the interaction between BRN2 protein and MORE DNA.

scientific article published on 27 August 2016

Larvicidal activity of essential oil of Peumus boldus Molina and its ascaridole-enriched fraction against Culex quinquefasciatus

scientific article published in November 2016

Methyl Chavicol and Its Synthetic Analogue as Possible Antioxidant and Antilipase Agents Based on the In Vitro and In Silico Assays.

scientific article

Octopus: a platform for the virtual high-throughput screening of a pool of compounds against a set of molecular targets

scientific article published on 7 January 2017

Pharmacophoric characteristics of dengue virus NS2B/NS3pro inhibitors: a systematic review of the most promising compounds.

scientific article published on 16 November 2017

Production, purification and characterization of a thermostable β-1,3-glucanase produced by Moniliophthora perniciosa.

scientific article

QM/QM studies for Michael reaction in coronavirus main protease (3CL Pro).

scientific article published on 9 May 2008

Rational selection of immunodominant and preserved epitope Sm043300e from Schistosoma mansoni and design of a chimeric molecule for biotechnological purposes

scientific article published on 22 November 2017

Selectivity analyses of γ-benzylidene digoxin derivatives to different Na,K-ATPase α isoforms: a molecular docking approach

scientific article published in December 2018

Structure-based drug design studies of UDP-N-acetylglucosamine pyrophosphosrylase, a key enzyme for the control of witches' broom disease.

scientific article

Structure-based drug design studies of the interactions of ent-kaurane diterpenes derived from Wedelia paludosa with the Plasmodium falciparum sarco/endoplasmic reticulum Ca²⁺-ATPase PfATP6.

scientific article published on April 2015

Successful application of virtual screening and molecular dynamics simulations against antimalarial molecular targets

scientific article published on 10 November 2016

Synthesis, SAR, and Docking Studies Disclose 2-Arylfuran-1,4-naphthoquinones as In Vitro Antiplasmodial Hits

scientific article published on 31 October 2017

The Use of Reverse Vaccinology and Molecular Modeling Associated with Cell Proliferation Stimulation Approach to Select Promiscuous Epitopes from Schistosoma mansoni.

scientific article published on 16 March 2016

γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na,K-ATPase activity effect.

scientific article

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