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List of works by Fiorella Tonello

A Lys49-PLA2 myotoxin of Bothrops asper triggers a rapid death of macrophages that involves autocrine purinergic receptor signaling.

scientific article

Active-site mutagenesis of tetanus neurotoxin implicates TYR-375 and GLU-271 in metalloproteolytic activity

scientific article published on 01 August 2001

Anthrax Edema Factor, Voltage-dependent Binding to the Protective Antigen Ion Channel and Comparison to LF Binding

scientific article published in Journal of Biological Chemistry

Anthrax lethal factor (LF) mediated block of the anthrax protective antigen (PA) ion channel: effect of ionic strength and voltage

scientific article published in March 2006

Anthrax toxins inhibit immune cell chemotaxis by perturbing chemokine receptor signalling

scientific article published on 03 November 2006

Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling

scientific article

Anthrax toxins: A paradigm of bacterial immune suppression

scientific article published on 24 July 2006

Bacillus anthracis factors for phagosomal escape

scientific article

Bacillus anthracis: balancing innocent research with dual-use potential

scientific article published on 28 March 2008

Binding of N-terminal fragments of anthrax edema factor (EF(N)) and lethal factor (LF(N)) to the protective antigen pore

scientific article

Bontoxilysins

Bontoxilysins

Cell entry and cAMP imaging of anthrax edema toxin

scientific article published on 2 November 2006

Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A and mediates its toxic activity

scientific article published in Scientific Reports

Cellular Mechanisms of Action of Snake Phospholipase A2 Toxins

article published in 2015

Chemical synthesis of the RGD-protein decorsin: Pro-->Ala replacement reduces protein thermostability.

scientific article

Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes.

scientific article

DisProt 7.0: a major update of the database of disordered proteins

scientific article published on 13 December 2016

Enzymatic labelling of snake venom phospholipase A2 toxins

scientific article published on 26 September 2019

Glutamate exocytosis from astrocytes controls synaptic strength

scientific article published on 18 February 2007

Imaging the cell entry of the anthrax oedema and lethal toxins with fluorescent protein chimeras

scientific article published in October 2010

In vitro biological activity and toxicity of tetanus and botulinum neurotoxins

scientific article published in December 1998

Metal substitution of tetanus neurotoxin

scientific article published on March 1997

Nucleolin Rescues TDP-43 Toxicity in Yeast and Human Cell Models

scientific article published on 12 April 2021

Nucleolin internalizesBothrops asperLys49 phospholipase A2forming cell surface amyloid-like assemblies

Potent inhibitors of anthrax lethal factor from green tea

scientific article

Production in Escherichia coli, folding, purification and characterization of notexin with wild type sequence and with N-terminal and catalytic site mutations.

scientific article

Proteases

Protective activity and immunogenicity of two recombinant anthrax vaccines for veterinary use.

scientific article

Ratio of lethal and edema factors in rabbit systemic anthrax

scientific article published on 5 September 2008

Recombinant and Truncated Tetanus Neurotoxin Light Chain: Cloning, Expression, Purification, and Proteolytic Activity

Screening inhibitors of anthrax lethal factor

scientific article published on July 2002

Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo

scientific article

Stop the killer: how to inhibit the anthrax lethal factor metalloprotease

scientific article published on 01 June 2004

Structural Studies on the Zinc-endopeptidase Light Chain of Tetanus Neurotoxin

scientific article published in 1995

Tetanus and botulism neurotoxins: a novel group of zinc-endopeptidases.

scientific article published on January 1996

The Helicobacter pylori neutrophil-activating protein is an iron-binding protein with dodecameric structure.

scientific article published in October 1999

The adenylate cyclase toxin of Bacillus anthracis is a potent promoter of TH17 cell development

scientific article published on 09 February 2011

The anthrax lethal factor and its MAPK kinase-specific metalloprotease activity

scientific article published on 07 August 2009

The metalloproteolytic activity of the anthrax lethal factor is substrate-inhibited.

scientific article published on 29 July 2003

Tyrosine-728 and glutamic acid-735 are essential for the metalloproteolytic activity of the lethal factor of Bacillus anthracis.

scientific article published in January 2004

X-ray Absorption Spectroscopy Study of Zinc Coordination in Tetanus Neurotoxin, Astacin, Alkaline Protease and Thermolysin

scientific article published on 01 February 1996

cAMP imaging of cells treated with pertussis toxin, cholera toxin, and anthrax edema toxin

scientific article published on 13 September 2008

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