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List of works by Vasso Apostolopoulos

A 16-mer peptide (RQIKIWFQNRRMKWKK) from antennapedia preferentially targets the Class I pathway.

scientific article

A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity

scientific journal article

A double mutation of MBP83–99 peptide induces IL-4 responses and antagonizes IFN-γ responses

article

A functional hot spot for antigen recognition in a superagonist TCR/MHC complex

scientific article

A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor

scientific article

A heat shock protein 70-based vaccine with enhanced immunogenicity for clinical use.

scientific article

A membrane penetrating multiple antigen peptide (MAP) incorporating ovalbumin CD8 epitope induces potent immune responses in mice

scientific article published on 15 May 2010

A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes

scientific article

Active immunization with myelin-derived altered peptide ligand reduces mechanical pain hypersensitivity following peripheral nerve injury

scientific article

Advances in Multiple Sclerosis Research-Series I

scientific article published on 29 October 2020

Alamandine reverses hyperhomocysteinemia-induced vascular dysfunction via PKA-dependent mechanisms

scientific article published on 13 September 2017

Alteration of early dendritic cell activation by cancer cell lines predisposes immunosuppression, which cannot be reversed by TLR4 stimulation

scientific article published on 19 October 2016

Altered peptide ligands of myelin basic protein ( MBP87-99 ) conjugated to reduced mannan modulate immune responses in mice

article

Alveolar macrophage function is altered in patients with lung cancer

scientific article published on February 2006

An Effective Model for Prevention and Management of Type 2 Diabetes

scientific article published on 23 March 2015

Angiotensin (1-7) and Alamandine: Similarities and differences

scientific article

Antagonistic Effects of Human Cyclic MBP87-99Altered Peptide Ligands in Experimental Allergic Encephalomyelitis and Human T-Cell Proliferation

article

Anti-CD20 Agents for Multiple Sclerosis: Spotlight on Ocrelizumab and Ofatumumab

scientific article published on 20 October 2020

Anti-Tumor Effects of Vitamin B2, B6 and B9 in Promonocytic Lymphoma Cells

scientific article published on 01 August 2019

Anti-peptide monoclonal antibodies to intestinal mucin 3

article

Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein ⬇️

scientific article published on December 1, 1997

Antihypertensive drugs that act on Renin-Angiotensin System with emphasis in AT(1) antagonists.

scientific article

Applications of peptide mimetics in cancer.

scientific article

Aspects of cancer immunotherapy

scientific article

Assessment of Sodium Knowledge and Urinary Sodium Excretion among Regions of the United Arab Emirates: A Cross-Sectional Study

scientific article published on 09 September 2020

Bioimaging of C2C12 Muscle Myoblasts Using Fluorescent Carbon Quantum Dots Synthesized from Bread

scientific article published on 11 August 2020

Breast cancer and exercise: The role of adiposity and immune markers

scientific article

CHAPTER 19. Calcium-Fortified Soymilk: Function and Health Benefits

article

CRP and fibrinogen imply clinical outcome of patients with Type-2 diabetes and coronary artery disease

scholarly article by Marijan Bosevski et al published 23 January 2017 in Acta Biochimica et Biophysica Sinica

Cancer Vaccines: Research and Applications

scientific article published on 24 July 2019

Cancer vaccines: looking to the future. Interview by Jenaid Rees

scientific article published on 7 October 2013

Cancer vaccines: methods for inducing immunity

Cell-mediated immune responses to MUC1 fusion protein coupled to mannan

article

Cell-penetrating peptides: application in vaccine delivery

scientific article published on 25 September 2009

Characterization of blood monocyte phenotype in patients with endometrial cancer

scientific article published on November 2012

Characterization of mice lacking the tetraspanin superfamily member CD151

scientific journal article

Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease

scientific article published in December 2008

Cognitive decline: A vitamin B perspective

scientific article

Conformational studies of immunodominant myelin basic protein 1–11 analogues using NMR and molecular modeling

Conjugation of a peptide to mannan and its confirmation by tricine sodium dodecyl sulfate-polyacrylamide gel electrophoresis

scientific article published on 14 June 2015

Corrigendum to “Crystal Structure of a Non-canonical High-affinity Peptide Complexed with MHC Class I: A Novel Use of Alternative Anchors”

scholarly article published in Journal of Molecular Biology

Corrigendum to “Crystal Structure of a Non-canonical Low-affinity Peptide Complexed with MHC Class I: A New Approach for Vaccine Design”

scholarly article published in Journal of Molecular Biology

Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors

scientific article

Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design

scientific article

Cyclic MOG35-55 ameliorates clinical and neuropathological features of experimental autoimmune encephalomyelitis

scientific article published on 07 June 2017

Cyclic citrullinated MBP87-99 peptide stimulates T cell responses: Implications in triggering disease

scientific article published on 19 November 2016

Cytokine Production from Murine CD4 and CD8 Cells After Mannan-MUC1 Immunization

article

Cytokine profile and induction of T helper type 17 and regulatory T cells by human peripheral mononuclear cells after microbial exposure.

scientific article published on February 2012

Definition of MHC-restricted CTL epitopes from non-variable number of tandem repeat sequence of MUC1.

scientific article published in April 2000

Delivery of DNA vaccines: an overview on the use of biodegradable polymeric and magnetic nanoparticles

scientific article published on May 2010

Delivery of antigen using a novel mannosylated dendrimer potentiates immunogenicity in vitro and in vivo

scientific article

Delivery of tumor associated antigens to antigen presenting cells using penetratin induces potent immune responses

scientific article published on 25 January 2006

Dendritic Cells and Myeloid Derived Suppressor Cells Fully Responsive to Stimulation via Toll-Like Receptor 4 Are Rapidly Induced from Bone-Marrow Cells by Granulocyte-Macrophage Colony-Stimulating Factor

scientific article published on 12 September 2020

Dendritic cells induce immunity and long-lasting protection against blood-stage malaria despite an in vitro parasite-induced maturation defect

scientific article published on September 2004

Dendritic cells: activation and maturation--applications for cancer immunotherapy

scientific article

Design and Synthesis of Non-Peptide Mimetics Mapping the Immunodominant Myelin Basic Protein (MBP83-96) Epitope to Function as T-Cell Receptor Antagonists.

scientific article

Design and Synthesis of a Cyclic Double Mutant Peptide (cyclo(87−99)[A91,A96]MBP87−99) Induces Altered Responses in Mice after Conjugation to Mannan: Implications in the Immunotherapy of Multiple Sclerosis

article

Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators.

scientific article published on March 2005

Design of Linear and Cyclic Mutant Analogues of Dirucotide Peptide (MBP) against Multiple Sclerosis: Conformational and Binding Studies to MHC Class II

Design of novel cyclic altered peptide ligands of myelin basic protein MBP83-99 that modulate immune responses in SJL/J mice

scientific article published on 19 June 2008

Design of peptide-based vaccines for cancer.

scientific article published on January 2006

Design, synthesis and evaluation of an anthraquinone derivative conjugated to myelin basic protein immunodominant (MBP85-99) epitope: Towards selective immunosuppression

scientific article published on 24 November 2017

Designing Peptide Mimetics for the Treatment of Multiple Sclerosis

scientific article published on 01 September 2001

Development of allergic responses related to microorganisms exposure in early life

article

Development of more efficient and effective DNA vaccines

article

Direct processing and presentation of antigen from malaria sporozoites by professional antigen-presenting cells in the induction of CD8 T-cell responses

scientific article published in June 2005

Editorial [Hot topic: MHC and MHC-Like Molecules in the Design of Vaccines (Executive Editor: Vasso Apostolopoulos)]

scientific article published on 01 January 2009

Effects of active immunisation with myelin basic protein and myelin-derived altered peptide ligand on pain hypersensitivity and neuroinflammation

scientific article

Effects of fermented skim milk drink by Kluyveromyces marxianus LAF4 co-cultured with lactic acid bacteria to release angiotensin-converting enzyme inhibitory activities

Effects of vaccination with altered Peptide ligand on chronic pain in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis

scientific article published on 29 October 2013

Electrophoretic characterization of protein interactions suggesting limited feasibility of accelerated shelf-life testing of ultra-high temperature milk

scientific article published on 16 November 2016

Elevated serum interleukin-5 levels in severe chronic obstructive pulmonary disease

scientific article

Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide

scientific article published on November 2006

Eosinophils in Inflammatory Bowel Disease

scientific article published on 01 June 2019

Exercise and mental health

scientific article

Exercise in Menopausal Women

Extraction and Purification of Short-chain Fatty Acids from Fermented Reconstituted Skim Milk Supplemented with Inulin

Fourier transform infrared spectroscopy analysis of physicochemical changes in UHT milk during accelerated storage

Good, better, best? The effects of polarization on photobiomodulation therapy

scientific article published on 19 February 2020

Homology modeling and molecular dynamics simulations of MUC1-9/H-2Kb complex suggest novel binding interactions

Hormone Therapy Reduces Bone Resorption but not Bone Formation in Postmenopausal Athletes.

scientific article

Immune Modulatory Effects of Probiotic Streptococcus thermophilus on Human Monocytes

scientific article published in 2021

Immune responses of linear and cyclic PLP139-151 mutant peptides in SJL/J mice: peptides in their free state versus mannan conjugation

article

Immunogenetics and the design of Plasmodium falciparum vaccines for use in malaria-endemic populations

scholarly article by Magdalena Plebanski et al published 1 August 2002 in Journal of Clinical Investigation

Immunomodulatory effects of Streptococcus thermophilus on U937 monocyte cell cultures

article

Induction of T helper type 1 and 2 responses to 19-kilodalton merozoite surface protein 1 in vaccinated healthy volunteers and adults naturally exposed to malaria

scientific article

Induction of T1 (cytotoxic lymphocyte) and/or T2 (antibody) responses to a mucin-1 tumour antigen.

scientific article published on October 1997

Inflammatory biomarkers: impact for diabetes and diabetic vascular disease

scientific article published in 2015

Insights into peptide-based vaccine design for cancer immunotherapy

scientific article

Interview. Cancer vaccines and immunotherapy of autoimmune diseases

scientific article published in January 2009

Leucocyte-Rich Platelet-Rich Plasma Enhances Fibroblast and Extracellular Matrix Activity: Implications in Wound Healing

scientific article published on 06 September 2020

Leukocyte populations and IL-6 in the tumor microenvironment of an orthotopic colorectal cancer model

scientific article published on 17 February 2016

MHC and MHC-Like Molecules: Structural Perspectives on the Design of Molecular Vaccines

article

MHC and MHC-like molecules: structural perspectives on the design of molecular vaccines

scientific article

MUC1 (CD227): a multi-tasked molecule

scientific article published on 21 August 2015

MUC1 cross-reactive Galα(l,3)Gal antibodies in humans switch immune responses from cellular to humoral

article

MUC1 immunotherapy against a metastatic mammary adenocarcinoma model: Importance of IFN-gamma

scientific article published in June 2016

MUC1 peptide epitopes associated with five different H‐2 class I molecules ⬇️

scientific article published on October 1, 1997

Maca reduces blood pressure and depression, in a pilot study in postmenopausal women.

scientific article

Mannan derivatives induce phenotypic and functional maturation of mouse dendritic cells.

scientific article

Mannan-MUC1-pulsed dendritic cell immunotherapy: a phase I trial in patients with adenocarcinoma.

scientific article

Mannan-conjugated myelin peptides prime non-pathogenic Th1 and Th17 cells and ameliorate experimental autoimmune encephalomyelitis

scientific article published on 30 October 2014

Mannan-mediated gene delivery for cancer immunotherapy

scientific article published on March 2007

Mannosylated Linear and Cyclic Single Amino Acid Mutant Peptides Using a Small 10 Amino Acid Linker Constitute Promising Candidates Against Multiple Sclerosis

scientific article published on 7 April 2015

Mannosylation of mutated MBP83-99 peptides diverts immune responses from Th1 to Th2.

scientific article published on 9 June 2008

Methamphetamine: Effects on the brain, gut and immune system

scientific article published on 13 March 2017

Methods of Delivery to Antigen-Presenting Cells: Development of New and Improved Vaccines

article

Methods to measure T-cell responses

scientific article published on June 2010

Methods to measure vaccine immunity

scientific article

Mimics and cross reactions of relevance to tumour immunotherapy.

scientific article

Molecular basis of improved immunogenicity in DNA vaccination mediated by a mannan based carrier

article by Choon Kit Tang et al published March 2009 in Biomaterials

Multiple Sclerosis: Immunopathology and Treatment Update

scientific article

Myeloid derived suppressor cells and their role in diseases.

scientific article published on January 2013

Non-canonical anchor motif peptides bound to MHC class I induce cellular responses

article

Non-canonical peptides bound to MHC.

scientific article published on January 2009

Noncanonical peptides in complex with MHC class I.

scientific article published on April 2004

Oxaliplatin Treatment Alters Systemic Immune Responses

article

Oxidative/reductive conjugation of mannan to antigen selects for T1 or T2 immune responses.

scientific article

Oxidised mannan antigen conjugates preferentially stimulate T1 type immune responses

scientific article published in May 1998

Oxidized and reduced mannan mediated MUC1 DNA immunization induce effective anti-tumor responses

article

Parameters for using mannan-MUC1 fusion protein to induce cellular immunity

scientific article published on 01 February 1998

Pathogen recognition and development of particulate vaccines: does size matter?

scientific article published on September 2006

Penetratin tandemly linked to a CTL peptide induces anti-tumour T-cell responses via a cross-presentation pathway

article

Peptide Binding Sites Recognized by Anti-Mucin (MUC2) Monoclonal Antibodies

article

Peptide mimics of a tumor antigen induce functional cytotoxic T cells

scholarly article by Vasso Apostolopoulos et al published March 1998 in Nature Biotechnology

Peptide-based vaccines for cancer: are we choosing the right peptides?

Physical and immunological aspects of exercise in chronic diseases

scientific article

Pilot phase III immunotherapy study in early-stage breast cancer patients using oxidized mannan-MUC1 [ISRCTN71711835].

scientific article

Polarized light therapy: Shining a light on the mechanism underlying its immunomodulatory effects

scientific article published on 29 December 2019

Poly-L-lysine-coated nanoparticles: a potent delivery system to enhance DNA vaccine efficacy

scientific article published on 10 October 2006

Predicting sediment formation in ultra high temperature-treated whole and skim milk using attenuated total reflectance-Fourier transform infrared spectroscopy

Processing and sensory characteristics of a fermented low-fat skim milk drink containing bioactive antihypertensive peptides, a functional milk product

article by Fatah B Ahtesh et al published 27 October 2017 in International Journal of Dairy Technology

Production of anti-breast cancer monoclonal antibodies using a glutathione-S-transferase-MUC1 bacterial fusion protein ⬇️

scientific article published on April 1, 1993

Prognostic implications of myocardial perfusion imaging and coronary calcium score in a Macedonian cohort of asymptomatic patients with type 2 diabetes

scientific article published in April 2017

Progression of carotid artery disease could stratify a risk of coronary artery disease patients with type 2 diabetes

scientific article published on 01 January 2019

Properties of myelin altered peptide ligand cyclo(87-99)(Ala91,Ala96)MBP87-99 render it a promising drug lead for immunotherapy of multiple sclerosis.

scientific article

Protein/peptide and DNA vaccine delivery by targeting C-type lectin receptors

scientific article published on September 2008

Rare monkeypox: Is it really a threat to the elderly?

scientific article published on 09 June 2022

Reactive oxygen species level defines two functionally distinctive stages of inflammatory dendritic cell development from mouse bone marrow

scientific article published on 22 February 2010

Receptor-mediated delivery of antigens to dendritic cells: anticancer applications

scientific article published on 17 January 2007

Regulatory T-cells: immunomodulators in health and disease

scientific article published on January 2006

Resveratrol alleviates oxidative damage in enteric neurons and associated gastrointestinal dysfunction caused by chemotherapeutic agent oxaliplatin

scientific article published on 17 May 2017

Round and round we go: cyclic peptides in disease

scientific article published on January 2006

Selection and characterization of MUC1-specific CD8+ T cells from MUC1 transgenic mice immunized with dendritic-carcinoma fusion cells

article published in 2000

Self-adjuvanting multicomponent cancer vaccine candidates combining per-glycosylated MUC1 glycopeptides and the Toll-like receptor 2 agonist Pam3CysSer.

scientific article published on 7 January 2011

Short-Chain Fatty Acids Regulate Cytokines and Th17/Treg Cells in Human Peripheral Blood Mononuclear Cellsin vitro

Short-Chain Fatty Acids Regulate Secretion of IL-8 from Human Intestinal Epithelial Cell Lines in vitro

scientific article published on October 2015

Short-chain fatty acids produced by synbiotic mixtures in skim milk differentially regulate proliferation and cytokine production in peripheral blood mononuclear cells

article

Simultaneous immunisation with a Wilms’ Tumour 1 epitope and its ubiquitin fusions results in enhanced cell mediated immunity and tumour rejection in C57BL/6 mice

Strategies used for MUC1 immunotherapy: human clinical studies

scientific article published on September 2008

Strategies used for MUC1 immunotherapy: preclinical studies

scientific article published on September 2008

Streptococcus thermophilus ST285 Alters Pro-Inflammatory to Anti-Inflammatory Cytokine Secretion against Multiple Sclerosis Peptide in Mice

scientific article published on 23 February 2020

Structural Comparison of Allogeneic and Syngeneic T Cell Receptor–Peptide-Major Histocompatibility Complex Complexes

scientific article

Structural and dynamic consequences of increasing repeats in a MUC1 peptide tumor antigen

scientific article published in 2005

Structural elucidation of Leuprolide and its analogues in solution: insight into their bioactive conformation

scientific article

Structure and design of polycationic carriers for gene delivery

scientific article published on December 2006

Structure and function of the myelin proteins: current status and perspectives in relation to multiple sclerosis

scientific article

Synthesis and immunological evaluation of self-assembling and self-adjuvanting tricomponent glycopeptide cancer-vaccine candidates

scientific article

Synthesis and study of the electrophoretic behavior of mannan conjugates with cyclic peptide analogue of myelin basic protein using lysine-glycine linker

scientific article published on 3 October 2005

Tetraspanin CD37 contributes to the initiation of cellular immunity by promoting dendritic cell migration

scientific article published on 25 March 2013

Tetraspanins CD37 and CD151 differentially regulate Ag presentation and T-cell co-stimulation by DC.

scientific article

The Anti-Inflammatory Effect of Taurine on Cardiovascular Disease

scientific article published on 17 September 2020

The Complex Interaction between the Tumor Micro-Environment and Immune Checkpoints in Breast Cancer

scientific article published on 19 August 2019

The Effects of Hormonal Therapy and Exercise on Bone Turnover in Postmenopausal Women: A Randomised Double-Blind Pilot Study

scientific article published in November 2016

The Effects of Vitamin B in Depression

scientific article published on 20 September 2016

The Use of Electrochemical Voltammetric Techniques and High-Pressure Liquid Chromatography to Evaluate Conjugation Efficiency of Multiple Sclerosis Peptide-Carrier Conjugates

scientific article published on 21 August 2020

The adjuvanticity of a mannosylated antigen reveals TLR4 functionality essential for subset specialization and functional maturation of mouse dendritic cells

scientific article published in August 2008

The complex immunological and inflammatory network of adipose tissue in obesity

scientific article published on September 2015

The effects of vitamin B on the immune/cytokine network and their involvement in depression

scientific article published on 19 November 2016

The good, the bad and the ugly: how altered peptide ligands modulate immunity

The immunogenicity of MUC1 peptides and fusion protein.

scientific article published on March 1995

The mechanisms tumor cells utilize to evade the host's immune system

scientific article published on 27 April 2017

To exercise, or, not to exercise, during menopause and beyond

scientific article published on 24 January 2014

Towards immunotherapeutic drugs and vaccines against multiple sclerosis

scientific article published on July 2008

Understanding the Driving Forces That Trigger Mutations in SARS-CoV-2: Mutational Energetics and the Role of Arginine Blockers in COVID-19 Therapy

scientific article published on 11 May 2022

Unus pro omnibus, omnes pro uno: A novel, evidence-based, unifying theory for the pathogenesis of endometriosis.

scientific article published on 31 March 2017

Up to 15-year clinical follow-up of a pilot Phase III immunotherapy study in stage II breast cancer patients using oxidized mannan-MUC1.

scientific article published in November 2013

Vaccine Delivery Methods into the Future

scientific article published on 28 March 2016

Vaccine delivery by penetratin: mechanism of antigen presentation by dendritic cells

scientific article published on 2 May 2016

Vaccine development against Methamphetamine drug addiction

scientific article published on 30 November 2020

Vaccines in clinical trials: cancer ⬇️

scientific article published on June 1, 2011

Vitamin D enzymes (CYP27A1, CYP27B1, and CYP24A1) and receptor expression in non-melanoma skin cancer

scientific article published on 01 April 2019

Whole protein and defined CD8(+) and CD4(+) peptides linked to penetratin targets both MHC class I and II antigen presentation pathways

scientific article published on 8 March 2011

Why METH users are at high risk of fatality due to COVID-19 infection?

scientific article published on 30 November 2020

Yeast based spreads improve anxiety and stress

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