List of works - Juan José Martínez-Irujo

A new strategy to inhibit the excision reaction catalysed by HIV-1 reverse transcriptase: compounds that compete with the template-primer

scientific article published on July 2007

All-trans-retinoic acid inhibits collapsin response mediator protein-2 transcriptional activity during SH-SY5Y neuroblastoma cell differentiation

scientific article published on January 2007

Analysis of the combined effect of two linear inhibitors on a single enzyme ⬇️

scientific article published on February 1, 1998

Contribution of phosphodiesterase isoenzymes and cyclic nucleotide efflux to the regulation of cyclic GMP levels in aortic smooth muscle cells

scientific article published on 01 November 1999

Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51

scientific article published on 6 March 2016

Factors affecting the dimerization of the p66 form of HIV-1 reverse transcriptase

scientific article published on 01 March 2001

Fibronectin peptides as potential regulators of hepatic fibrosis through apoptosis of hepatic stellate cells.

scientific article

Flavonoids induce apoptosis in human leukemia U937 cells through caspase- and caspase-calpain-dependent pathways.

scientific article published in January 2004

Induction of Cyclooxygenase-2 by Overexpression of the Human NADPH Oxidase 5 (NOX5) Gene in Aortic Endothelial Cells

scientific article published on 06 March 2020

Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3'-azido-3'-deoxythymidine with nonnucleoside inhibitors

scientific article

Inhibitory effect against polymerase and ribonuclease activities of HIV-reverse transcriptase of the aqueous leaf extract of Terminalia triflora.

scientific article published on December 2002

NADPH oxidase 5 promotes proliferation and fibrosis in human hepatic stellate cells

scientific article published on 21 July 2018

New indole and pyridazinoindole analogs--synthesis and study as inhibitors of phosphodiesterases and as inhibitors of blood platelet aggregation

scientific article published on 01 October 1995

New indole and triazino[5,4-b]indol-4-one derivatives: synthesis and studies as inotropics and inhibitors of blood platelet aggregation.

scientific article published in July 1992

Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3'-azido-3'-deoxythymidine (AZT)-resistant polymerase to AZT-5'-triphosphate

scientific article published on 13 August 2003

Novel structural insights for imidoselenocarbamates with antitumoral activity related to their ability to generate methylselenol ⬇️

scientific article published on July 15, 2012

Oxidation pathways underlying the pro-oxidant effects of apigenin

scientific article

Recurrent exposure to nicotine differentiates human bronchial epithelial cells via epidermal growth factor receptor activation

scientific article published on 23 December 2007

Role of AGAP2 in the profibrogenic effects induced by TGFβ in LX-2 hepatic stellate cells

scientific article published on 17 January 2019

Selective Excision of Chain-terminating Nucleotides by HIV-1 Reverse Transcriptase with Phosphonoformate as Substrate

scientific article published in Journal of Biological Chemistry

Synergistic inhibition of HIV-1 reverse transcriptase by combinations of chain-terminating nucleotides.

scientific article

TGFbeta-induced protein mediates lymphatic endothelial cell adhesion to the extracellular matrix under low oxygen conditions.

scientific article

Two ellagitannins from the leaves of Terminalia triflora with inhibitory activity on HIV-1 reverse transcriptase

scientific article published on 01 August 2004

Unfolded protein response induced by Brefeldin A increases collagen type I levels in hepatic stellate cells through an IRE1α, p38 MAPK and Smad-dependent pathway.

scientific article published on 4 May 2016

List of works by Juan José Martínez-Irujo

A new strategy to inhibit the excision reaction catalysed by HIV-1 reverse transcriptase: compounds that compete with the template-primer

All-trans-retinoic acid inhibits collapsin response mediator protein-2 transcriptional activity during SH-SY5Y neuroblastoma cell differentiation

Analysis of the combined effect of two linear inhibitors on a single enzyme ⬇️

Contribution of phosphodiesterase isoenzymes and cyclic nucleotide efflux to the regulation of cyclic GMP levels in aortic smooth muscle cells

Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51

Factors affecting the dimerization of the p66 form of HIV-1 reverse transcriptase

Fibronectin peptides as potential regulators of hepatic fibrosis through apoptosis of hepatic stellate cells.

Flavonoids induce apoptosis in human leukemia U937 cells through caspase- and caspase-calpain-dependent pathways.

Induction of Cyclooxygenase-2 by Overexpression of the Human NADPH Oxidase 5 (NOX5) Gene in Aortic Endothelial Cells

Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3'-azido-3'-deoxythymidine with nonnucleoside inhibitors

Inhibitory effect against polymerase and ribonuclease activities of HIV-reverse transcriptase of the aqueous leaf extract of Terminalia triflora.

NADPH oxidase 5 promotes proliferation and fibrosis in human hepatic stellate cells

New indole and pyridazinoindole analogs--synthesis and study as inhibitors of phosphodiesterases and as inhibitors of blood platelet aggregation

New indole and triazino[5,4-b]indol-4-one derivatives: synthesis and studies as inotropics and inhibitors of blood platelet aggregation.

Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3'-azido-3'-deoxythymidine (AZT)-resistant polymerase to AZT-5'-triphosphate

Novel structural insights for imidoselenocarbamates with antitumoral activity related to their ability to generate methylselenol ⬇️

Oxidation pathways underlying the pro-oxidant effects of apigenin

Recurrent exposure to nicotine differentiates human bronchial epithelial cells via epidermal growth factor receptor activation

Role of AGAP2 in the profibrogenic effects induced by TGFβ in LX-2 hepatic stellate cells

Selective Excision of Chain-terminating Nucleotides by HIV-1 Reverse Transcriptase with Phosphonoformate as Substrate

Synergistic inhibition of HIV-1 reverse transcriptase by combinations of chain-terminating nucleotides.

TGFbeta-induced protein mediates lymphatic endothelial cell adhesion to the extracellular matrix under low oxygen conditions.

Two ellagitannins from the leaves of Terminalia triflora with inhibitory activity on HIV-1 reverse transcriptase

Unfolded protein response induced by Brefeldin A increases collagen type I levels in hepatic stellate cells through an IRE1α, p38 MAPK and Smad-dependent pathway.