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List of works by Maria L. Lozano

A Novel GATA1 Variant in the C-Terminal Zinc Finger Compared with the Platelet Phenotype of Patients with A Likely Pathogenic Variant in the N-Terminal Zinc Finger

scientific article published in 2022

A Radioreceptor Assay for Mass Measurement of Inositol (1,4,5)-Trisphosphate Using Saponin-Permeabilized Outdated Human Platelets

scientific article published in February 1998

A common polymorphism flanking the ATG initiator codon of GPIb alpha does not affect expression and is not a major risk factor for arterial thrombosis

scientific article published in January 2000

A common polymorphism in the annexin V Kozak sequence (-1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients

scientific article published on 15 September 2002

A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect

scientific article published on 16 December 2020

ABO blood group does not increase the risk of thrombosis in Philadelphia-negative myeloproliferative disorders

scientific article published in July 2009

Allogeneic hematopoietic cell transplantation in an adult patient with Glanzmann thrombasthenia

scientific article published on 5 October 2017

An atypical IgM class platelet cold agglutinin induces GPVI-dependent aggregation of human platelets.

scientific article

An early increase of CD56bright natural killer subset as dominant effect and predictor of response to extracorporeal photopheresis for graft-versus-host disease

scientific article published on 27 September 2018

An innovative flow cytometric approach for small-size platelet microparticles: influence of calcium

scientific article published on 28 June 2012

Antithrombotic prophylaxis for surgery-associated venous thromboembolism risk in patients with inherited platelet disorders. The SPATA-DVT Study

scientific article published on 26 September 2019

Apigenin inhibits platelet adhesion and thrombus formation and synergizes with aspirin in the suppression of the arachidonic acid pathway

scientific article

Avatrombopag for the management of thrombocytopenia in patients with chronic liver disease

scientific article published on 25 November 2020

Biallelic Mutations in KDSR Disrupt Ceramide Synthesis and Result in a Spectrum of Keratinization Disorders Associated with Thrombocytopenia

scientific article published on 31 July 2017

Binding of recombinant apolipoprotein(a) to human platelets and effect on platelet aggregation

scientific article published in April 2001

Bleeding risk of surgery and its prevention in patients with inherited platelet disorders

scientific article published on 6 April 2017

Bone marrow steady-state CD34+/CD71- cell content is a predictive value of rG-CSF-mobilized CD34+ cells.

scientific article published in May 1998

Chediak-Higashi syndrome: description of two novel homozygous missense mutations causing divergent clinical phenotype.

scientific article published on 24 October 2013

Circulating microRNAs in patients with immune thrombocytopenia before and after treatment with thrombopoietin-receptor agonists

scientific article published on 18 March 2019

Comparative assessment of prophylactic transfusions of platelet concentrates obtained by the PRP or buffy-coat methods, in patients undergoing allogeneic hematopoietic stem cell transplantation

scientific article published on 27 March 2018

Comparative study of three methods to detect free plasma antiplatelet antibodies.

scientific article

Corrigendum to “Generation of induced pluripotent stem cells (iPSCs) from a Bernard-Soulier syndrome patient carrying a W71R mutation in the GPIX gene” [Stem Cell Res. 16/3 (2016) 692–695]

scientific article published in September 2016

Current treatment of primary immune thrombocytopenia

scientific article

Deciphering predictive factors for choice of thrombopoietin receptor agonist, treatment free responses, and thrombotic events in immune thrombocytopenia

scientific article published on 13 November 2019

Design and application of a 23-gene panel by next-generation sequencing for inherited coagulation bleeding disorders.

scientific article published on 15 February 2016

Differences in phycoerythrin- or fluorescein-isothiocyanate conjugated 8G12 on CD34+ cell evaluation ⬇️

scientific article published on May 1, 1997

Differential effects of quercetin, apigenin and genistein on signalling pathways of protease-activated receptors PAR(1) and PAR(4) in platelets.

scientific article published on 8 October 2009

Down Regulation of the Munc18b-syntaxin-11 Complex and β1-tubulin Impairs Secretion and Spreading in Neonatal Platelets

scientific article published on 10 October 2017

Effect of cold-storage in the accumulation of bioreactive substances in platelet concentrates treated with second messenger effects

scientific article published in May 2001

Effect of rhG-CSF on the mobilization of CD38 and HLA-DR subfractions of CD34+ peripheral blood progenitor cells

scientific article published in September 1995

Evaluation of Novel Platelet Polymorphisms in Stroke. Dichotomic Effect of rs5443 in GNB3.

scientific article

Evaluation of a new whole-blood filter that allows preparation of platelet concentrates by platelet-rich plasma methods

scientific article published in December 2003

Evaluation of four rapid methods for hemoglobin screening of whole blood donors in mobile collection settings.

scientific article

Evaluation of platelet function during extended storage in additive solution, prepared in a new container that allows manual buffy-coat platelet pooling and leucoreduction in the same system.

scientific article

Evaluation of pooled platelet concentrates using prestorage versus poststorage WBC reduction: impact of filtration timing

scientific article published in July 2000

Evaluation of refrigerated platelet concentrates supplemented with low doses of second messenger effectors.

scientific article

Evaluation of two-step haemoglobin screening with HemoCue for blood donor qualification in mobile collection sites.

scientific article published on 11 June 2014

Flavonoids inhibit the platelet TxA(2) signalling pathway and antagonize TxA(2) receptors (TP) in platelets and smooth muscle cells.

scientific article

GENYOi005-A: An induced pluripotent stem cells (iPSCs) line generated from a patient with Familial Platelet Disorder with associated Myeloid Malignancy (FPDMM) carrying a p.Thr196Ala variant

scientific article published on 15 October 2019

GPI-anchor and GPI-anchored protein expression in PMM2-CDG patients

scientific article

Generation of a human induced pluripotent stem cell (iPSC) line from a Bernard-Soulier syndrome patient with the mutation p.Asn45Ser in the GPIX gene.

scientific article

Generation of induced pluripotent stem cells (iPSCs) from a Bernard-Soulier syndrome patient carrying a W71R mutation in the GPIX gene.

scientific article published on 15 April 2016

Genotype-phenotype relationship for six common polymorphisms in genes affecting platelet function from 286 healthy subjects and 160 patients with mucocutaneous bleeding of unknown cause.

scientific article published on 21 April 2009

Hematologic β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity.

scientific article

Hermansky-Pudlak syndrome. Overview of clinical and molecular features and case report of a new HPS-1 variant.

scientific article published on 13 August 2014

High on-treatment platelet reactivity in patients with ischemic cerebrovascular disease

scientific article published in September 2014

Identification of novel variants in ten patients with Hermansky-Pudlak syndrome by high-throughput sequencing

scientific article published on 01 March 2019

Identification of two novel mutations in RASGRP2 affecting platelet CalDAG-GEFI expression and function in patients with bleeding diathesis.

scientific article published in August 2017

IgM monoclonal component associated with type I Gaucher disease resolved after enzyme replacement therapy: A case report

scientific article published on 27 June 2009

Immune recovery after autologous or rhG-CSF primed PBSC transplantation

scientific article published in May 1996

Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: Mechanisms and implications

scientific article published on 01 December 2019

Impaired leucocyte activation is underlining the lower thrombotic risk of essential thrombocythaemia patients with CALR mutations as compared with those with the JAK2 mutation.

scientific article

In vitro analysis of platelet concentrates stored in the presence of modulators of 3′,5′ adenosine monophosphate, and organic anions

scientific article published in February 2000

Induced pluripotent stem cells derived from Bernard-Soulier Syndrome patient's peripheral blood cells with a p.Phe55Ser mutation in the GPIX gene

scientific article published on 11 February 2017

Influence of CYP2C19 Polymorphisms in Platelet Reactivity and Prognosis in an Unselected Population of Non ST Elevation Acute Coronary Syndrome

scientific article published in March 2012

Introducing high-throughput sequencing into mainstream genetic diagnosis practice in inherited platelet disorders.

scientific article published on 5 October 2017

JAK2 V617F, hemostatic polymorphisms, and clinical features as risk factors for arterial thrombotic events in essential thrombocythemia

scientific article published on 26 March 2008

Latent and polymeric antithrombin: clearance and potential thrombotic risk

scientific article published in February 2007

Loss of high-affinity thrombin receptors during platelet concentrate storage impairs the reactivity of platelets to thrombin

scientific article published in April 1997

Management of Adult Patients with Primary Immune Thrombocytopenia (ITP) in Clinical Practice: A Consensus Approach of the Spanish ITP Expert Group

scientific article published on 22 August 2019

Markers of endothelial cell activation and neutrophil extracellular traps are elevated in immune thrombocytopenia but are not enhanced by thrombopoietin receptor agonists

scientific article published on 30 November 2019

MicroRNAs as potential regulators of platelet function and bleeding diatheses

scientific article published on 22 May 2018

Migraine and prothrombotic genetic risk factors

scientific article

Molecular Diagnosis of Inherited Coagulation and Bleeding Disorders

scientific article published on 30 April 2019

Multirefractory primary immune thrombocytopenia; targeting the decreased sialic acid content

scholarly article by Nuria Revilla et al published 8 October 2018 in Platelets

New alleles of the platelet glycoprotein Ibalpha gene

scientific article published in December 1998

Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction

scientific article published on 27 May 2016

Performance and usefulness of platelet aggregation testing

scientific article published on 23 July 2018

Persistent cytotoxic T lymphocyte expansions after allogeneic haematopoietic stem cell transplantation: kinetics, clinical impact and absence of STAT3 mutations.

scientific article

Phenotype description and response to thrombopoietin receptor agonist in -related disorder

scientific article published on 01 September 2018

Platelet activation and neutrophil extracellular trap (NET) formation in immune thrombocytopenia: is there an association?

scientific article published on 24 November 2019

Platelet concentrates from whole-blood donations (buffy-coat) or apheresis: which one to use? ⬇️

scientific article published on July 31, 2011

Platelet cryopreservation using a reduced dimethyl sulfoxide concentration and second-messenger effectors as cryopreserving solution

scientific article published on 01 August 1999

Platelet receptors and signaling in the dynamics of thrombus formation.

scientific article published on 13 March 2009

Polymorphisms of platelet membrane glycoprotein Ib associated with arterial thrombotic disease.

scientific article published in October 1998

Prospective Randomized Study Comparing the Efficacy of Bioequivalent Doses of glycosylated and nonglycosylated rG-CSF for Mobilizing Peripheral Blood Progenitor Cells

scientific article published in February 1997

Proteomic analysis of platelet N-glycoproteins in PMM2-CDG patients.

scientific article published on 21 December 2013

Quality assessment and transfusion efficacy of buffy coat-derived platelet concentrates washed with platelet additive solution.

scientific article published on 13 April 2017

Quality assessment of buffy-coat-derived leucodepleted platelet concentrates in PAS-plasma, prepared by the OrbiSac or TACSI automated system

scientific article published on 28 July 2013

Quality assessment of platelet concentrates supplemented with second-messenger effectors

scientific article published in February 1999

RASGRP2 gene variations associated with platelet dysfunction and bleeding

scientific article published on 08 March 2019

Rare homozygous status of P43 β1-tubulin polymorphism causes alterations in platelet ultrastructure.

scientific article published on 8 March 2011

Re-mobilization of peripheral blood progenitor cells within a short time interval fails to achieve effective progenitor cell yields

scientific article published on 28 July 2000

Real-life management of primary immune thrombocytopenia (ITP) in adult patients and adherence to practice guidelines

scientific article

Retrospective Multicenter Study of Extracorporeal Photopheresis in Steroid-Refractory Acute and Chronic Graft-versus-Host Disease

scientific article published on 07 January 2020

Romiplostim in adults with newly diagnosed or persistent immune thrombocytopenia

scientific article published on 30 November 2020

Significant Hypo-Responsiveness to GPVI and CLEC-2 Agonists in Pre-Term and Full-Term Neonatal Platelets and following Immune Thrombocytopenia.

scientific article

Successful mobilization of hematopoietic peripheral blood progenitor cells with paclitaxel-based chemotherapy as initial or salvage regimen in patients with hematologic malignancies

scientific article published in September 2008

The venous thrombosis risk factor 20210 A allele of the prothrombin gene is not a major risk factor for arterial thrombotic disease.

scientific article published in November 1997

Thrombopoietin receptor agonists in conjunction with oseltamivir for immune thrombocytopenia

scientific article published in April 2016

Towards the targeted management of Chediak-Higashi syndrome

scientific article

Transfusión de plaquetas, ¿concentrados procedentes de un único o de múltiples donantes?

scientific article published in January 2004

Transient desialylation in combination with a novel antithrombin deficiency causing a severe and recurrent thrombosis despite anticoagulation therapy

scientific article published on 17 March 2017

Trasplante de progenitores hematopoyéticos de sangre periférica en España: análisis de coste

scientific article published on 01 October 2004

Two novel variants of the ABCG5 gene cause xanthelasmas and macrothrombocytopenia: a brief review of hematological abnormalities of sitosterolemia

scientific article

Utilización de las heparinas de bajo peso molecular en la enfermedad tromboembólica

scientific article published in January 2000

Valor pronóstico del factor de necrosis tumoral alfa en pacientes con infarto agudo de miocardio con elevación del segmento ST

scientific article published in December 2007

Wiskott-Aldrich syndrome in a child presenting with macrothrombocytopenia.

scientific article

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