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List of works by Alaa Othman

1-Deoxysphingolipid-induced neurotoxicity involves N-methyl-d-aspartate receptor signaling.

scientific article published on 22 March 2016

A Novel Variant (Asn177Asp) in SPTLC2 Causing Hereditary Sensory Autonomic Neuropathy Type 1C

scientific article published on 06 April 2019

A functional analysis of 180 cancer cell lines reveals conserved intrinsic metabolic programs

scientific article published in November 2022

Altered sphingoid base profiles in type 1 compared to type 2 diabetes

scientific article

Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate

scientific article

Astrocyte glutathione maintains endothelial barrier stability

scientific article published on 19 May 2020

Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitus

scientific article

Brain endothelial specific gene therapy improves experimental Sandhoff disease

scientific article published on 29 July 2019

Cell-Derived Vesicles as TRPC1 Channel Delivery Systems for the Recovery of Cellular Respiratory and Proliferative Capacities

scientific article published on 02 September 2020

Circulating microRNAs -192 and -194 are associated with the presence and incidence of diabetes mellitus

scientific article published in Scientific Reports

Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway

scientific article published on 21 November 2016

DEGS1-associated aberrant sphingolipid metabolism impairs nervous system function in humans

Decreased phosphatidylcholine plasmalogens--A putative novel lipid signature in patients with stable coronary artery disease and acute myocardial infarction

scientific article published on 6 January 2016

Defects in high density lipoprotein metabolism and hepatic steatosis in mice with liver-specific ablation of hepatocyte nuclear factor 4α

scientific article published on 02 July 2020

Deoxysphingoid bases as plasma markers in diabetes mellitus

scientific article

Deoxysphingolipids, novel biomarkers for type 2 diabetes, are cytotoxic for insulin-producing cells

scientific article published on 30 December 2013

Elevation of plasma 1-deoxy-sphingolipids in type 2 diabetes mellitus: a susceptibility to neuropathy?

scientific article published on 26 January 2015

Elucidating the chemical structure of native 1-deoxysphingosine

scientific article published on 10 May 2016

Explaining ionic liquid water solubility in terms of cation and anion hydrophobicity.

scientific article published on 18 March 2009

Fenofibrate lowers atypical sphingolipids in plasma of dyslipidemic patients: A novel approach for treating diabetic neuropathy?

scientific article published on 4 April 2015

HSAN1 mutations in serine palmitoyltransferase reveal a close structure-function-phenotype relationship.

scientific article

Hyperglycemia in Stroke Impairs Polarization of Monocytes/Macrophages to a Protective Noninflammatory Cell Type.

scientific article published in September 2016

Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration

scientific article published on 13 March 2019

Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction.

scientific article published on 23 November 2016

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.

scientific article published on 12 April 2018

Lowering Plasma 1-Deoxysphingolipids Improves Neuropathy in Diabetic Rats

scientific article published on 02 October 2014

MS2 and LC libraries for untargeted metabolomics: Enhancing method development and identification confidence

scientific article published on 04 April 2020

Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPARγ signature

scientific article published on 01 March 2020

Neurotoxic 1-deoxysphingolipids and paclitaxel-induced peripheral neuropathy

scientific article

Novel HSAN1 mutation in serine palmitoyltransferase resides at a putative phosphorylation site that is involved in regulating substrate specificity

scientific article

Obesity-induced activation of JunD promotes myocardial lipid accumulation and metabolic cardiomyopathy

scientific article published on 01 March 2019

Peak-fitting and integration imprecision in the Aerodyne aerosol mass spectrometer: effects of mass accuracy on location-constrained fits

article by J. C. Corbin et al published 3 November 2015 in Atmospheric Measurement Techniques

Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus

scientific article

Plasma 1-deoxysphingolipids are predictive biomarkers for type 2 diabetes mellitus

scientific article

Plasma C20-Sphingolipids predict cardiovascular events independently from conventional cardiovascular risk factors in patients undergoing coronary angiography

scientific article published on 14 March 2015

Plasma deoxysphingolipids: a novel class of biomarkers for the metabolic syndrome?

scientific article published on 29 November 2011

Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism

scientific article

Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control

scientific article published on 24 October 2015

Plasmalogens of high-density lipoproteins (HDL) are associated with coronary artery disease and anti-apoptotic activity of HDL.

scientific article published on 9 June 2015

Structure-function relationships of HDL in diabetes and coronary heart disease

scientific article published on 16 January 2020

Telmisartan prevents development of obesity and normalizes hypothalamic lipid droplets

scientific article published on 01 January 2020

The AT1 Receptor Blocker Telmisartan Reduces Intestinal Mucus Thickness in Obese Mice

scientific article published on 31 March 2022

Viral serine palmitoyltransferase induces metabolic switch in sphingolipid biosynthesis and is required for infection of a marine alga

scientific article published on 16 March 2016

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