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List of works by Jan F. Stevens

18O-Tracer Metabolomics Reveals Protein Turnover and CDP-Choline Cycle Activity in Differentiating 3T3-L1 Pre-Adipocytes

scientific article

A dihydroflavonol with taxonomic significance from the fern Notholaena sulphurea.

scientific article

A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol

scientific article published on 14 May 2013

A novel 2-hydroxyflavanone from collinsonia canadensis

scientific article published on 01 February 1999

Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract.

scientific article

Acrolein

scientific article published on 01 September 2011

Amelioration of Metabolic Syndrome-Associated Cognitive Impairments in Mice via a Reduction in Dietary Fat Content or Infusion of Non-Diabetic Plasma.

scientific article published on 12 December 2015

Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro

scientific article published on 01 September 2000

Antiproliferative and Cytotoxic Activity of Xanthohumol and Its Non-Estrogenic Derivatives in Colon and Hepatocellular Carcinoma Cell Lines ⬇️

scientific article published on 09 March 2019

Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines.

scientific article

Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome

scientific article published on 08 March 2017

Application of Paper Strip Extraction in Combination with LC-MS-MS in Pharmacokinetics.

scientific article published on October 2013

Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells

scientific article published on May 2009

Ascorbylated 4-hydroxy-2-nonenal as a potential biomarker of oxidative stress response

scientific article published on 14 July 2005

Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design.

scientific article

C-methyl-flavonoids from the leaf waxes of some Myrtaceae

scientific article published on 01 December 2000

CYP2K6 from zebrafish (Danio rerio): cloning, mapping, developmental/tissue expression, and aflatoxin B1 activation by baculovirus expressed enzyme.

scientific article published in February 2005

Caffeoylquinic Acids in Centella asiatica Reverse Cognitive Deficits in Male 5XFAD Alzheimer's Disease Model Mice

scientific article published on 13 November 2020

Caffeoylquinic acids in Centella asiatica protect against amyloid-β toxicity.

scientific article published on January 2014

Centella asiatica water extract shows low potential for CYP-mediated drug interactions

scientific article published on 24 June 2020

Comparison of isothiocyanate metabolite levels and histone deacetylase activity in human subjects consuming broccoli sprouts or broccoli supplement

scientific article

Comprehensive analysis of phospholipids in the brain, heart, kidney, and liver: brain phospholipids are least enriched with polyunsaturated fatty acids

scientific article published on 9 October 2017

Computation-Assisted Identification of Bioactive Compounds in Botanical Extracts: A Case Study of Anti-Inflammatory Natural Products from Hops

scientific article published in 2022

Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies.

scientific article published on 2 September 2016

Design, synthesis, and application of a hydrazide-functionalized isotope-coded affinity tag for the quantification of oxylipid-protein conjugates

scientific article

Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion

scientific article

Distribution of alkaloids and tannins in the Crassulaceae

scientific article published in 1995

EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol ⬇️

scientific article

Effects of Time and Storage Conditions on the Chemical and Microbiologic Stability of Diluted Buprenorphine for Injection

scientific article published on July 2017

Electrospray Quadrupole Travelling Wave Ion Mobility Time-of-Flight Mass Spectrometry for the Detection of Plasma Metabolome Changes Caused by Xanthohumol in Obese Zucker (fa/fa) Rats

scientific article published on 13 August 2013

Exudate flavonoids in some Gnaphalieae and Inuleae (Asteraceae).

scientific article

Fate of xanthohumol and related prenylflavonoids from hops to beer

scientific article published on 01 June 1999

Flavin-containing monooxygenase S-oxygenation of a series of thioureas and thiones.

scientific article

Flavonoids: separation and quantitation.

scientific article published in March 2015

Formation of a vitamin C conjugate of acrolein and its paraoxonase-mediated conversion into 5,6,7,8-tetrahydroxy-4-oxooctanal

scientific article

Functional food--where do we go?

scientific article published in 2014

Germ-Free Swiss Webster Mice on a High-Fat Diet Develop Obesity, Hyperglycemia, and Dyslipidemia

scientific article published on 05 April 2020

Herbicidal activity of glucosinolate degradation products in fermented meadowfoam ( Limnanthes alba ) seed meal ⬇️

scientific article

High-resolution image workstation for intensive care units.

scientific article published on July 1994

Hop proanthocyanidins induce apoptosis, protein carbonylation, and cytoskeleton disorganization in human colorectal adenocarcinoma cells via reactive oxygen species.

scientific article

Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione

scientific article

Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops

scientific article

Identification and phytotoxicity of a new glucosinolate breakdown product from Meadowfoam (Limnanthes alba) seed meal

scientific article published on 16 July 2014

Identification of isoflavones in the roots of Pueraria lobata.

scientific article

Identifying Rates of Meadowfoam (Limnanthes alba) Seed Meal Needed for Suppression of Meloidogyne hapla and Pythium irregulare in Soil

scientific article published on 01 September 2014

In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus

article published in 2000

Inhibition of peroxynitrite-mediated LDL oxidation by prenylated flavonoids: the alpha,beta-unsaturated keto functionality of 2'-hydroxychalcones as a novel antioxidant pharmacophore.

scientific article published in October 2003

Isolation and Identification of Tyrosinase-Inhibitory and Copper-Chelating Peptides from Hydrolyzed Rice-Bran-Derived Albumin

scientific article published on 31 July 2018

Isolation and identification of antioxidant peptides from enzymatically hydrolyzed rice bran protein.

scientific article

Isolation of two cytotoxic diterpenes from the fern Pteris multifida.

scientific article published in September 1996

LC‐MS/MS Quantitation of Mercapturic Acid Conjugates of Lipid Peroxidation Products as Markers of Oxidative Stress ⬇️

scientific article published on February 1, 2011

Lethal dysregulation of energy metabolism during embryonic vitamin E deficiency

scientific article

Linden (Tilia cordata) associated bumble bee mortality: Metabolomic analysis of nectar and bee muscle

scientific article published on 10 July 2019

Lipid quantitation and metabolomics data from vitamin E-deficient and -sufficient zebrafish embryos from 0 to 120 hours-post-fertilization

scientific article

Lipidomics and H2(18)O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos

scientific article published on 11 January 2016

Mass spectrometry-based quantification of myocardial protein adducts with acrolein in an in vivo model of oxidative stress.

scientific article published on 2 August 2011

Mass tagging approach for mitochondrial thiol proteins.

scientific article published in July 2005

Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice

scientific article

Metabolomic analysis to define and compare the effects of PAHs and oxygenated PAHs in developing zebrafish

scientific article

Metabolomics-Driven Elucidation of Cellular Nitrate Tolerance Reveals Ascorbic Acid Prevents Nitroglycerin-Induced Inactivation of Xanthine Oxidase

scholarly article by Elizabeth Rose Axton et al published 2018 in Frontiers in Pharmacology

Mitochondria-Centric Review of Polyphenol Bioactivity in Cancer Models.

scientific article published on 30 October 2017

Nitrate and nitrite exposure leads to mild anxiogenic-like behavior and alters brain metabolomic profile in zebrafish

scientific article published on 31 December 2020

Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice

scientific article

Novel function of vitamin E in regulation of zebrafish (Danio rerio) brain lysophospholipids discovered using lipidomics.

scientific article published on 8 April 2015

Novel liquid chromatography-mass spectrometry method shows that vitamin E deficiency depletes arachidonic and docosahexaenoic acids in zebrafish (Danio rerio) embryos

scientific article published on 17 December 2013

On the occurrence of exudate flavonoids in the borage family (Boraginaceae)

scientific article published on 01 May 2002

Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.

scientific article

Photoprotective Properties of Isothiocyanate and Nitrile Glucosinolate Derivatives From Meadowfoam (Limnanthes alba) Against UVB Irradiation in Human Skin Equivalent.

scientific article published on 15 May 2018

Phytochemical Investigation and Reproductive Capacity of the Bulgarian Endemic Plant Species Marrubium friwaldskyanum Boiss. (Lamiaceae)

scientific article published in 2021

Prenylated chalcones and flavanones as inducers of quinone reductase in mouse Hepa 1c1c7 cells.

scientific article

Prenylflavonoid variation in Humulus lupulus: distribution and taxonomic significance of xanthogalenol and 4'-O-methylxanthohumol

scientific article published on 01 April 2000

Reductive Metabolism of Xanthohumol and 8-Prenylnaringenin by the Intestinal Bacterium Eubacterium ramulus

scientific article published on 03 December 2018

Rice Protein Matrix Enhances Circulating Levels of Xanthohumol Following Acute Oral Intake of Spent Hops in Humans.

scientific article published on 11 January 2018

Roles of the sodium-translocating NADH:quinone oxidoreductase (Na+-NQR) on vibrio cholerae metabolism, motility and osmotic stress resistance.

scientific article

S-oxygenation of the thioether organophosphate insecticides phorate and disulfoton by human lung flavin-containing monooxygenase 2.

scientific article

Scoping dietary supplements versus botanical medicines

scientific article published in 2015

Simultaneous, untargeted metabolic profiling of polar and nonpolar metabolites by LC-Q-TOF mass spectrometry

scientific article published on May 2013

Site-specific protein adducts of 4-hydroxy-2(E)-nonenal in human THP-1 monocytic cells: protein carbonylation is diminished by ascorbic acid.

scientific article

Stable isotope-assisted LC-MS/MS monitoring of glyceryl trinitrate bioactivation in a cell culture model of nitrate tolerance

scientific article published on 24 December 2015

Sulforaphane absorption and histone deacetylase activity following single dosing of broccoli sprout supplement in normal dogs

scientific article published on 17 August 2018

The Chemistry of Gut Microbial Metabolism of Polyphenols

scientific article

Total synthesis of [13 C]2 -, [13 C]3 -, and [13 C]5 -isotopomers of xanthohumol, the principal prenylflavonoid from hops.

scientific article

Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish

scientific article published on 01 December 2019

Untargeted Metabolomic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts.

scientific article published on 28 January 2018

Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts

scientific article published on 05 March 2020

Vitamin C deficiency activates the purine nucleotide cycle in zebrafish

scientific article published on 13 December 2011

Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans

scientific article

Vitamins C and E: Beneficial effects from a mechanistic perspective ⬇️

scientific article published on May 25, 2011

Withania somnifera Extracts Promote Resilience against Age-Related and Stress-Induced Behavioral Phenotypes in Drosophila melanogaster; a Possible Role of Other Compounds besides Withanolides

scientific article published in 2022

Xanthohumol and related prenylated flavonoids inhibit inflammatory cytokine production in LPS-activated THP-1 monocytes: structure-activity relationships and in silico binding to myeloid differentiation protein-2 (MD-2).

scientific article published on 22 March 2010

Xanthohumol and related prenylflavonoids from hops and beer: to your good health!

scientific article

Xanthohumol improved cognitive flexibility in young mice.

scientific article

Xanthohumol improves dysfunctional glucose and lipid metabolism in diet-induced obese C57BL/6J mice

scientific article published on 11 March 2016

Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats

scientific article

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