List of works by Christian R. Engwerda

4th Australasian Vaccines and Immunotherapeutic Development Meeting

article

A molecular signature for CD8+ T cells from visceral leishmaniasis patients

scientific article published on 30 September 2019

A novel pathway of haematopoiesis revealed after experimental malaria infection

scientific article published on 20 July 2010

A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria

scientific article

A study of the TNF/LTA/LTB locus and susceptibility to severe malaria in highland papuan children and adults

scientific article

ASI 2009: Immunology “down under”

scientific article published on 01 August 2009

Activation of invariant NKT cells exacerbates experimental visceral leishmaniasis

scientific article

Age-related susceptibility to severe malaria associated with galectin-2 in highland Papuans

scientific article

An Age-Related Decrease in Rescue from T Cell Death Following Costimulation Mediated by CD28

scientific article published on 01 May 1996

An antioxidant link between sickle cell disease and severe malaria

scientific article published in April 2011

An in vivo analysis of cytokine production during Leishmania donovani infection in scid mice.

scientific article published on November 1996

Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria

scientific article published on 08 July 2013

Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis

scientific article published on 14 January 2020

Balancing immunity and pathology in visceral leishmaniasis

scientific article

Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.

scientific article published on 14 January 2016

Bromelain activates murine macrophages and natural killer cells in vitro.

scientific article published on May 2001

Bromelain modulates T cell and B cell immune responses in vitro and in vivo.

scientific article published on May 2001

CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo

scientific article

CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria

scientific article published on 22 May 2014

CD95 is required for the early control of parasite burden in the liver of Leishmania donovani-infected mice.

scientific article published on April 2001

CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease.

scientific article

Characterising the mucosal and systemic immune responses to experimental human hookworm infection

scientific article published on 9 February 2012

Characterization of blood dendritic and regulatory T cells in asymptomatic adults with sub-microscopic Plasmodium falciparum or Plasmodium vivax infection

scientific article

Coinfection with Blood-Stage Plasmodium Promotes Systemic Type I Interferon Production during Pneumovirus Infection but Impairs Inflammation and Viral Control in the Lung

scientific article published on 25 February 2015

Combined Immune Therapy for the Treatment of Visceral Leishmaniasis

scientific article

Common strategies to prevent and modulate experimental cerebral malaria in mouse strains with different susceptibilities

scientific article

Critical roles for LIGHT and its receptors in generating T cell-mediated immunity during Leishmania donovani infection

scientific article

Cross-species malaria immunity induced by chemically attenuated parasites

scientific article

Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis

scientific article published on 18 November 2002

Defying malaria: Arming T cells to halt malaria

scientific article published in January 2011

Development and regulation of cell-mediated immune responses to the blood stages of malaria: implications for vaccine research

scientific article

Development of Leishmania vaccines in the era of visceral leishmaniasis elimination

article

Disarming the malaria parasite

scientific article published in September 2008

Distinct Roles for CD4 Foxp3 Regulatory T Cells and IL-10-Mediated Immunoregulatory Mechanisms during Experimental Visceral Leishmaniasis Caused by

scientific article published on 24 October 2018

Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease.

scientific article published on 13 July 2015

Effect of mature blood-stage Plasmodium parasite sequestration on pathogen biomass in mathematical and in vivo models of malaria.

scientific article

Enhanced hematopoietic activity accompanies parasite expansion in the spleen and bone marrow of mice infected with Leishmania donovani

scientific article

Eomesodermin promotes the development of type 1 regulatory T (TR1) cells.

scientific article

Experimental asexual blood stage malaria immunity

scientific article published in April 2011

Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease.

scientific article published on 20 September 2014

Experimentally induced blood stage malaria infection as a tool for clinical research.

scientific article published on 04 October 2012

Gammaherpesvirus Co-infection with Malaria Suppresses Anti-parasitic Humoral Immunity

scientific article

Genetic variation in tumour necrosis factor and lymphotoxin is not associated with endometriosis in an Australian sample

article

Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria

scientific article published on 27 April 2011

Hepatocytes break the silence during liver-stage malaria

scientific article

High parasite burdens cause liver damage in mice following Plasmodium berghei ANKA infection independently of CD8(+) T cell-mediated immune pathology

scientific article

Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria

scientific article published on 07 June 2009

IFN Regulatory Factor 3 Balances Th1 and T Follicular Helper Immunity during Nonlethal Blood-Stage Plasmodium Infection

scientific article published on 10 January 2018

IFN differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract

article

IL-17A-Producing γδ T Cells Suppress Early Control of Parasite Growth by Monocytes in the Liver.

scientific article published on 4 November 2015

IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection

scientific article published on 13 October 2020

IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection

scientific article

Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.

scientific article

IgE, TNFα, IL1 β, IL4 and IFNγ gene polymorphisms in sheep selected for resistance to fleece rot and flystrike

article

IgM in human immunity to Plasmodium falciparum malaria

scientific article published on 25 September 2019

Immune Checkpoint Targets for Host-Directed Therapy to Prevent and Treat Leishmaniasis

scientific article published on 8 November 2017

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

scientific article published on 13 March 2012

Immune regulation during chronic visceral leishmaniasis

scientific article

Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria

scientific article published on 18 August 2010

Immunity to visceral leishmaniasis

scientific article published on 28 December 2011

Immunology. Platelets kill the parasite within

scientific article published in December 2012

Induction of natural killer T cell-dependent alloreactivity by administration of granulocyte colony-stimulating factor after bone marrow transplantation

scientific article published on 29 March 2009

Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria

scientific article published on 18 May 2020

Interactions between malaria parasites and the host immune system

scientific article

Interleukin 2 is an Upstream Regulator of CD4+ T Cells From Visceral Leishmaniasis Patients With Therapeutic Potential

scientific article published on 01 June 2019

Isolation and sequence of sheep immunoglobulin E heavy-chain complementary DNA.

scholarly article

Laser microdissection microscopy in parasitology: microscopes meet thermocyclers

scientific article

Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria

scientific article published on May 2002

Low doses of killed parasite in CpG elicit vigorous CD4+ T cell responses against blood-stage malaria in mice.

scientific article

Low-level Plasmodium falciparum blood-stage infection causes dendritic cell apoptosis and dysfunction in healthy volunteers.

scientific article published on 21 May 2012

Lymphotoxin alpha and tumour necrosis factor are not required for control of parasite growth, but differentially regulate cytokine production during Plasmodium chabaudi chabaudi AS infection.

scientific article published in March 2007

Macrophages, pathology and parasite persistence in experimental visceral leishmaniasis

scientific article

Mast cells fuel the fire of malaria immunopathology

scientific article

Murine cerebral malaria: the whole story

scientific article published on 8 April 2010

Neutralization of IL-12 demonstrates the existence of discrete organ-specific phases in the control of Leishmania donovani.

scientific article published on February 1998

Ovalbumin lipid core peptide vaccines and their CD4(+) and CD8(+) T cell responses

scientific article published on 23 June 2014

Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria

scientific article

Parasites and the immune system: a perspective from down under

scientific article published on 01 August 2010

Peripheral Blood Monocytes With an Antiinflammatory Phenotype Display Limited Phagocytosis and Oxidative Burst in Patients With Visceral Leishmaniasis

scientific article published on 01 August 2018

Plasmodium berghei ANKA (PbA) infection of C57BL/6J mice: a model of severe malaria.

scientific article published in January 2013

Plasmodium berghei bio-burden correlates with parasite lactate dehydrogenase: application to murine Plasmodium diagnostics

scientific article

Preserved dendritic cell HLA-DR expression and reduced regulatory T cell activation in asymptomatic Plasmodium falciparum and P. vivax infection

scientific article published on June 2015

Recent insights into humoral and cellular immune responses against malaria

scientific article published on 08 October 2008

Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease

scientific article

Soluble lymphotoxin is an important effector molecule in GVHD and GVL.

scientific article published on 29 September 2009

Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection

scientific article published on 13 November 2014

Suppression of inflammatory immune responses in celiac disease by experimental hookworm infection

scientific article

TNF family members and malaria: old observations, new insights and future directions

scientific article published on 28 April 2010

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

scientific article published on 24 August 2020

The Regulation of CD4(+) T Cell Responses during Protozoan Infections

scientific article

The Schistosoma mansoni hepatic egg granuloma provides a favorable microenvironment for sustained growth of Leishmania donovani

scientific article

The diverse roles of monocytes in inflammation caused by protozoan parasitic diseases

scientific article published on 30 August 2012

The immunopathology of experimental visceral leishmaniasis

scientific article published in October 2004

The importance of the spleen in malaria

scientific article

The isolation and sequence of sheep interleukin 4

scientific article published on January 1, 1992

The regulation of CD4+ T cells during malaria

scientific article published on 01 November 2019

Therapeutic glucocorticoid-induced TNF receptor-mediated amplification of CD4+ T cell responses enhances antiparasitic immunity

scientific article published on 5 February 2010

Tissue requirements for establishing long-term CD4+ T cell-mediated immunity following Leishmania donovani infection

scientific article published on 14 March 2014

Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection

scientific article published on 18 June 2020

Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity

scientific article

Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection

scientific article published on October 2016

Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

scientific article published on 01 February 2020

Type I interferons suppress CD4⁺ T-cell-dependent parasite control during blood-stage Plasmodium infection

scientific article published on 8 August 2011

UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6c(low)MHCII(hi) macrophages.

scientific article published on 15 January 2013

VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis

scientific article

Where have all the parasites gone? Modelling early malaria parasite sequestration dynamics

scientific article published on 18 February 2013

Paulina is supported by:

About Paulina

Help