List of works - Philippe Christen

2-(4-Bromo-phen-yl)-N-[3-(1H-imidazol-1-yl)prop-yl]quinazolin-4-amine

scientific article published on 30 June 2012

5',6'-dehydroguiachrysine and 5',6'-dehydroguiaflavine, two curarizing quaternary indole alkaloids from the stem bark of Strychnos guianensis.

scientific article

A new antifungal and antiprotozoal bibenzyl derivative from Gavilea lutea

scientific article published on 8 June 2017

A novel acylated flavonol glycoside isolated from Brunfelsia grandiflora ssp. grandiflora. Structure elucidation by gradient accelerated NMR spectroscopy at 14T

scientific article published on 25 August 2002

Absolute configuration of tropane alkaloids bearing two alpha,beta-unsaturated ester functions using electronic CD spectroscopy: application to (R,R)-trans-3-hydroxysenecioyloxy-6-senecioyloxytropane

scientific article published in January 2008

Alkaloids as Inhibitors of Monoamine Oxidases and Their Role in the Central Nervous System

Alkaloids of Erythroxylum lucidum stem-bark

Alkaloids of Erythroxylum zambesiacum stem-bark☆

article

Alkaloids of erythroxylum monogynum root-bark

article

Alkaloids of hairy root cultures of a Datura candida hybrid

article

An iridoid diester from valeriana officinalis var. sambucifolia hairy roots

Analysis of Tropane Alkaloids in Biological Matrices

Analysis of isomeric tropane alkaloids from Schizanthus grahamii by very fast gas chromatography

scientific article published in January 2006

Analysis of the neurotoxin anisatin in star anise by LC-MS/MS.

scientific article published on 27 June 2013

Analytical discrimination of poisonous and nonpoisonous chemotypes of giant fennel (Ferula communis L.) through their biologically active and volatile fractions

scientific article published in October 2006

Anti-inflammatory and Quinone Reductase-Inducing Compounds from Beilschmiedia mannii

scientific article published on 22 November 2018

Anti-inflammatory and antiproliferative diterpenoids from Plectranthus scutellarioides

scientific article published on 28 June 2018

Antifungal Quinoline Alkaloids from Waltheria indica

scientific article published on 5 February 2016

Antiproliferative activity of compounds isolated from the root bark of Lannea acida in multiple myeloma cell lines

scientific article published on 10 March 2023

Antiproliferative effects of withanolides from Withania adpressa

scientific article published on March 2009

Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica

scientific article published on 14 October 2014

Azepine-Indole Alkaloids From Psychotria nemorosa Modulate 5-HT2A Receptors and Prevent in vivo Protein Toxicity in Transgenic Caenorhabditis elegans

scientific article published in 2022

Bioactive Azepine-Indole Alkaloids from Psychotria nemorosa

scientific article published on 09 March 2020

Bioactive metabolites from the leaves of Withania adpressa

scientific article published on 01 December 2018

Calystegine distribution in some solanaceous species

scientific article published in October 2001

Calystegines in wild and cultivated Erythroxylum species.

scientific article

Cancer chemopreventive activity of compounds isolated from Waltheria indica

scientific article published on 27 March 2017

Cannabis Profiling: Which Analytical Strategy to Apply?

Capillary electrophoresis for the analysis of tropane alkaloids: pharmaceutical and phytochemical applications

scientific article published on 01 December 1998

Characteristics of growth and tropane alkaloid production in Hyoscyamus albus hairy roots transformed with Agrobacterium rhizogenes A4. ⬇️

scientific article published on November 1992

Characterization of positional and configurational tropane alkaloid isomers by combining GC with NPD, MS and FTIR.

scientific article published in October 2009

ChemInform Abstract: 5′,6′-Dehydroguiachrysine and 5′,6′-Dehydroguiaflavine, Two Curarizing Quaternary Indole Alkaloids from the Stem Bark of Strychnos guianensis

scientific article published on 21 May 2010

Chemical constituents from Waltheria indica exert in vitro activity against Trypanosoma brucei and T. cruzi.

scientific article published on 11 June 2015

Chemical study and anti-inflammatory, analgesic and antioxidant activities of the leaves of Aristotelia chilensis (Mol.) Stuntz, Elaeocarpaceae

scientific article published on 3 May 2011

Chirality and numbering of substituted tropane alkaloids.

scientific article published on 25 August 2011

Cocaine distribution in wild Erythroxylum species

scientific article

Determination of Artemisinin in Artemisia annua L. by Off-Line Supercritical Fluid Extraction and Supercritical Fluid Chromatography Coupled to an Evaporative Light-Scattering Detector

Determination of alkaloids in endemic Genista quadriflora Munby (Fabaceae)

scientific article published in 2014

Determination of artemisinin and artemisinic acid by capillary and packed supercritical fluid chromatography

scientific article published in 1997

Development and validation of a capillary zone electrophoresis method for the determination of atropine, homatropine and scopolamine in ophthalmic solutions ⬇️

scientific article published on August 29, 1997

Development and validation of liquid chromatography and capillary electrophoresis methods for acarbose determination in pharmaceutical tablets

article

Enantioseparation of atropine by capillary electrophoresis using sulfated beta-cyclodextrin: application to a plant extract

scientific article published in February 2000

Essential oils from normal and hairy roots of Valeriana officinalis var. sambucifolia

Evaluation of solid-phase microextraction desorption parameters for fast GC analysis of cocaine in coca leaves

scientific article published in August 2006

Experimental design for enantioselective separation of celiprolol by capillary electrophoresis using sulfated beta-cyclodextrin

scientific article published in November 1999

Experimental design in supercritical fluid extraction of cocaine from coca leaves

scientific article published in July 2000

Extraction and analysis of different Cannabis samples by headspace solid-phase microextraction combined with gas chromatography-mass spectrometry

scientific article

Extraction of artemisinin and artemisinic acid from Artemisia annua L. using supercritical carbon dioxide

scientific article published on 01 October 1997

Flavonoids fromLycium halimifolium1

scientific article published on 01 December 1987

Focused microwave-assisted extraction combined with solid-phase microextraction and gas chromatography-mass spectrometry for the selective analysis of cocaine from coca leaves

scientific article published on 27 December 2005

Focused microwave-assisted extraction of cocaine and benzoylecgonine from coca leaves.

scientific article published in May 2002

Grahamines A–E, Cyclobutane-Centered Tropane Alkaloids from the Aerial Parts ofSchizanthus grahamii

scientific article published on 02 November 2011

Guiaflavine, a New Bisindole Quaternary Alkaloid from the Stem Bark ofStrychnosguianensis

scientific article published on 01 June 1999

Hairy roots of Datura candida × D. aurea: effect of culture medium composition on growth and alkaloid biosynthesis

article

Headspace Solid-Phase Microextraction of Pesticide Residues in Cannabis Samples

High-precision heteronuclear 2D NMR experiments using 10-ppm spectral window to resolve carbon overlap

scientific article published on 20 January 2009

High-yield production of tropane alkaloids by hairy-root cultures of aDatura candida hybrid

article

High-yield production of valepotriates by hairy root cultures of Valeriana officnalis L. var. sambucifolia Mikan

article

Identification of isomeric tropane alkaloids from Schizanthus grahamii by HPLC-NMR with loop storage and HPLC-UV-MS/SPE-NMR using a cryogenic flow probe

scientific article

In vitro shoot and root organogenesis, plant regeneration and production of tropane alkaloids in some species of Schizanthus

scientific article published on 20 January 2006

Inability of Unpacked Gooseneck Liners To Stop the Sample Liquid after Injection with Band Formation (Fast Autosampler) into Hot GC Injectors

scientific article published on 01 March 2004

Influence of plant matrix on microwave-assisted extraction process. The case of diosgenin extracted from fenugreek (Trigonella foenum-graecum L.).

scientific article published in January 2007

Inhibition of Cholinergic Contractions of Rat Ileum by Tropane-Type Alkaloids Present in Schizanthus hookeri

article published in 2013

Inhibition of Cholinergic Contractions of Rat Ileum by Tropane-Type Alkaloids Present in Schizanthus hookeri

scientific article published in 2013

Inhibition of cholinergic contractions of rat ileum by tkopane-type alkaloids present in Schizanthus hookeri

Isomeric tropane alkaloids from the aerial parts of Schizanthus tricolor.

scientific article published in May 2010

Kinetic study of littorine rearrangement in Datura innoxia hairy roots by (13)C NMR spectroscopy

scientific article

Medicinal Plants of Chile: Evaluation of their Anti-Trypanosoma cruzi Activity

scientific article published in 2013

Medicinal Plants of Chile: Evaluation of their Anti-Trypanosoma cruzi Activity

article

Methods of Analysis: Tropane Alkaloids from Plant Origin

article

Microwave-assisted extraction of the main phenolic compounds in flaxseed

Molecular biodiversity and recent analytical developments: a marriage of convenience.

scientific article

Multi-targeted screening of botanicals in food supplements by liquid chromatography with tandem mass spectrometry

scientific article published on 10 November 2012

NASCA-HMBC, a New NMR Methodology for the Resolution of Severely Overlapping Signals: Application to the Study of Agathisflavone

scientific article published on 19 May 2011

New Trends in the Extraction of Natural Products: Microwave-Assisted Extraction and Pressurized Liquid Extraction

Non-aqueous capillary electrophoresis with diode array and electrospray mass spectrometric detection for the analysis of selected steroidal alkaloids in plant extracts.

scientific article published in July 2001

Nonaqueous versus aqueous capillary electrophoresis for the dosage of N-butylscopolamine in various pharmaceutical formulations

scientific article published on 01 October 1999

Occurrence of Natural Hepatotoxins in Herbal Teas

article by Stefan Bieri et al published 29 April 2015 in Chimia

Occurrence of circadian rhythms in hairy root cultures grown under controlled conditions

scientific article published in December 2004

Optimisation of accelerated solvent extraction of cocaine and benzoylecgonine from coca leaves

scholarly article by Anne Brachet et al published 1 November 2001 in Journal of Separation Science

Parameters affecting microwave-assisted extraction of withanolides.

scientific article published in September 2001

Passive Intestinal Absorption of Representative Plant Secondary Metabolites: A Physicochemical Study

scientific article published on 13 February 2017

Plants as a Source of Therapeutic and Health Products ⬇️

scientific article published on January 1, 2012

Prediction of the Passive Intestinal Absorption of Medicinal Plant Extract Constituents with the Parallel Artificial Membrane Permeability Assay (PAMPA).

scientific article published on 12 February 2016

Production of valepotriates by hairy root cultures of Centranthus ruber DC

article

Pyridine-4(1H)-one Alkaloids from Waltheria indica as Antitrypanosomatid Agents ⬇️

scientific article published on 23 October 2020

Quaternary indole alkaloids from the stem bark of Strychnos guianensis

scientific article published in April 2000

Recent extraction techniques for natural products: microwave-assisted extraction and pressurised solvent extraction.

scientific article

Regiospecific synthesis of 1,4,5-trisubstituted 1,2,3-triazoles via enolate–azide cycloaddition between 1,3-dicarbonyl compounds and aryl azides

Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana

scientific article

SYNTHESIS AND ANTIFUNGAL ACTIVITY OF DIARYL HYDRAZONES FROM 2,4-DINITROPHENYLHYDRAZINE

Schizanthines N, O, and P, Tropane Alkaloids from the Aerial Parts ofSchizanthus tricolor

scientific article published on 20 December 2010

Screening and determination of sibutramine in adulterated herbal slimming supplements by HPTLC-UV densitometry

scientific article published on 15 January 2014

Selectivity manipulation using nonaqueous capillary electrophoresis. Application to tropane alkaloids and amphetamine derivatives

scientific article published on 01 November 1998

Separation of four isomeric tropane alkaloids from Schizanthus grahamii by non-aqueous capillary electrophoresis

scientific article

Simultaneous determination of scopolamine, hyoscyamine and littorine in plants and different hairy root clones of Hyoscyamus muticus by micellar electrokinetic chromatography

article

Spectral aliasing: a super zoom for 2D-NMR spectra. Principles and applications.

scientific article published on January 2010

Stability of prednisolone and prednisolone acetate in various vehicles used in semi-solid topical preparations.

scientific article published on October 1990

Structure and Dynamic of Three Indole Alkaloids from theCampylospermumGenus (Ochnaceae)

Survey of pyrrolizidine alkaloids in teas and herbal teas on the Swiss market using HPLC-MS/MS.

scientific article published on 7 October 2014

Synthesis and antifungal activity of phenacyl azoles

Synthesis and in vitro evaluation of tropane halogenated-derivatives against malaria, sleeping sickness, Chagas disease and leishmaniasis

scientific article published on January 2014

Targeted Isolation of Monoterpene Indole Alkaloids from Palicourea sessilis

scientific article published on 9 November 2017

The evaporative light scattering detector: some applications in pharmaceutical analysis

article

Two New Hygroline and Tropane Alkaloids Isolated from Schizanthus hookeri and S. tricolor (Solanaceae)

scientific article published on 01 March 2017

Unexpected occurrence of caffeine in sleep-inducing herbal teas

scientific article published in October 2014

Use of a Doehlert design in optimizing the analysis of selected tropane alkaloids by micellar electrokinetic capillary chromatography

article

Use of borate complexation for the separation of non-UV-absorbing calystegines by capillary electrophoresis

scientific article published on 01 December 2000

Use of porous graphitic carbon column for the separation of natural isomeric tropane alkaloids by capillary LC and mass spectrometry

scientific article published on 18 August 2005

Validated capillary electrophoresis method for the determination of atropine and scopolamine derivatives in pharmaceutical formulations.

scientific article published in September 1998

Withanolide. Naturstoffe mit vielversprechendem Wirkungsspektrum

scientific article published on 01 September 1989

Withanolides fromWithania adpressa

scholarly article by Lalla Hasna Abdeljebbar et al published February 2007 in Helvetica Chimica Acta

List of works by Philippe Christen

2-(4-Bromo-phen-yl)-N-[3-(1H-imidazol-1-yl)prop-yl]quinazolin-4-amine

5',6'-dehydroguiachrysine and 5',6'-dehydroguiaflavine, two curarizing quaternary indole alkaloids from the stem bark of Strychnos guianensis.

A new antifungal and antiprotozoal bibenzyl derivative from Gavilea lutea

A novel acylated flavonol glycoside isolated from Brunfelsia grandiflora ssp. grandiflora. Structure elucidation by gradient accelerated NMR spectroscopy at 14T

Absolute configuration of tropane alkaloids bearing two alpha,beta-unsaturated ester functions using electronic CD spectroscopy: application to (R,R)-trans-3-hydroxysenecioyloxy-6-senecioyloxytropane

Alkaloids as Inhibitors of Monoamine Oxidases and Their Role in the Central Nervous System

Alkaloids of Erythroxylum lucidum stem-bark

Alkaloids of Erythroxylum zambesiacum stem-bark☆

Alkaloids of erythroxylum monogynum root-bark

Alkaloids of hairy root cultures of a Datura candida hybrid

An iridoid diester from valeriana officinalis var. sambucifolia hairy roots

Analysis of Tropane Alkaloids in Biological Matrices

Analysis of isomeric tropane alkaloids from Schizanthus grahamii by very fast gas chromatography

Analysis of the neurotoxin anisatin in star anise by LC-MS/MS.

Analytical discrimination of poisonous and nonpoisonous chemotypes of giant fennel (Ferula communis L.) through their biologically active and volatile fractions

Anti-inflammatory and Quinone Reductase-Inducing Compounds from Beilschmiedia mannii

Anti-inflammatory and antiproliferative diterpenoids from Plectranthus scutellarioides

Antifungal Quinoline Alkaloids from Waltheria indica

Antiproliferative activity of compounds isolated from the root bark of Lannea acida in multiple myeloma cell lines

Antiproliferative effects of withanolides from Withania adpressa

Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica

Azepine-Indole Alkaloids From Psychotria nemorosa Modulate 5-HT2A Receptors and Prevent in vivo Protein Toxicity in Transgenic Caenorhabditis elegans

Bioactive Azepine-Indole Alkaloids from Psychotria nemorosa

Bioactive metabolites from the leaves of Withania adpressa

Calystegine distribution in some solanaceous species

Calystegines in wild and cultivated Erythroxylum species.

Cancer chemopreventive activity of compounds isolated from Waltheria indica

Cannabis Profiling: Which Analytical Strategy to Apply?

Capillary electrophoresis for the analysis of tropane alkaloids: pharmaceutical and phytochemical applications

Characteristics of growth and tropane alkaloid production in Hyoscyamus albus hairy roots transformed with Agrobacterium rhizogenes A4. ⬇️

Characterization of positional and configurational tropane alkaloid isomers by combining GC with NPD, MS and FTIR.

ChemInform Abstract: 5′,6′-Dehydroguiachrysine and 5′,6′-Dehydroguiaflavine, Two Curarizing Quaternary Indole Alkaloids from the Stem Bark of Strychnos guianensis

Chemical constituents from Waltheria indica exert in vitro activity against Trypanosoma brucei and T. cruzi.

Chemical study and anti-inflammatory, analgesic and antioxidant activities of the leaves of Aristotelia chilensis (Mol.) Stuntz, Elaeocarpaceae

Chirality and numbering of substituted tropane alkaloids.

Cocaine distribution in wild Erythroxylum species

Determination of Artemisinin in Artemisia annua L. by Off-Line Supercritical Fluid Extraction and Supercritical Fluid Chromatography Coupled to an Evaporative Light-Scattering Detector

Determination of alkaloids in endemic Genista quadriflora Munby (Fabaceae)

Determination of artemisinin and artemisinic acid by capillary and packed supercritical fluid chromatography

Development and validation of a capillary zone electrophoresis method for the determination of atropine, homatropine and scopolamine in ophthalmic solutions ⬇️

Development and validation of liquid chromatography and capillary electrophoresis methods for acarbose determination in pharmaceutical tablets

Enantioseparation of atropine by capillary electrophoresis using sulfated beta-cyclodextrin: application to a plant extract

Essential oils from normal and hairy roots of Valeriana officinalis var. sambucifolia

Evaluation of solid-phase microextraction desorption parameters for fast GC analysis of cocaine in coca leaves

Experimental design for enantioselective separation of celiprolol by capillary electrophoresis using sulfated beta-cyclodextrin

Experimental design in supercritical fluid extraction of cocaine from coca leaves

Extraction and analysis of different Cannabis samples by headspace solid-phase microextraction combined with gas chromatography-mass spectrometry

Extraction of artemisinin and artemisinic acid from Artemisia annua L. using supercritical carbon dioxide

Flavonoids fromLycium halimifolium1

Focused microwave-assisted extraction combined with solid-phase microextraction and gas chromatography-mass spectrometry for the selective analysis of cocaine from coca leaves

Focused microwave-assisted extraction of cocaine and benzoylecgonine from coca leaves.

Grahamines A–E, Cyclobutane-Centered Tropane Alkaloids from the Aerial Parts ofSchizanthus grahamii

Guiaflavine, a New Bisindole Quaternary Alkaloid from the Stem Bark ofStrychnosguianensis

Hairy roots of Datura candida × D. aurea: effect of culture medium composition on growth and alkaloid biosynthesis

Headspace Solid-Phase Microextraction of Pesticide Residues in Cannabis Samples

High-precision heteronuclear 2D NMR experiments using 10-ppm spectral window to resolve carbon overlap

High-yield production of tropane alkaloids by hairy-root cultures of aDatura candida hybrid

High-yield production of valepotriates by hairy root cultures of Valeriana officnalis L. var. sambucifolia Mikan

Identification of isomeric tropane alkaloids from Schizanthus grahamii by HPLC-NMR with loop storage and HPLC-UV-MS/SPE-NMR using a cryogenic flow probe

In vitro shoot and root organogenesis, plant regeneration and production of tropane alkaloids in some species of Schizanthus

Inability of Unpacked Gooseneck Liners To Stop the Sample Liquid after Injection with Band Formation (Fast Autosampler) into Hot GC Injectors

Influence of plant matrix on microwave-assisted extraction process. The case of diosgenin extracted from fenugreek (Trigonella foenum-graecum L.).

Inhibition of Cholinergic Contractions of Rat Ileum by Tropane-Type Alkaloids Present in Schizanthus hookeri

Inhibition of Cholinergic Contractions of Rat Ileum by Tropane-Type Alkaloids Present in Schizanthus hookeri

Inhibition of cholinergic contractions of rat ileum by tkopane-type alkaloids present in Schizanthus hookeri

Isomeric tropane alkaloids from the aerial parts of Schizanthus tricolor.

Kinetic study of littorine rearrangement in Datura innoxia hairy roots by (13)C NMR spectroscopy

Medicinal Plants of Chile: Evaluation of their Anti-Trypanosoma cruzi Activity

Medicinal Plants of Chile: Evaluation of their Anti-Trypanosoma cruzi Activity

Methods of Analysis: Tropane Alkaloids from Plant Origin

Microwave-assisted extraction of the main phenolic compounds in flaxseed

Molecular biodiversity and recent analytical developments: a marriage of convenience.

Multi-targeted screening of botanicals in food supplements by liquid chromatography with tandem mass spectrometry

NASCA-HMBC, a New NMR Methodology for the Resolution of Severely Overlapping Signals: Application to the Study of Agathisflavone

New Trends in the Extraction of Natural Products: Microwave-Assisted Extraction and Pressurized Liquid Extraction

Non-aqueous capillary electrophoresis with diode array and electrospray mass spectrometric detection for the analysis of selected steroidal alkaloids in plant extracts.

Nonaqueous versus aqueous capillary electrophoresis for the dosage of N-butylscopolamine in various pharmaceutical formulations

Occurrence of Natural Hepatotoxins in Herbal Teas

Occurrence of circadian rhythms in hairy root cultures grown under controlled conditions