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List of works by David F Choy

A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma.

scientific article published on 8 March 2017

A dual-labeling method to quantify unscheduled DNA synthesis in primary cells

scientific article published on 17 January 2008

A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production

scientific article

A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial

scientific article

Accurately measuring and modeling Th2 and Th17 endotypes in severe asthma

scientific article published on February 2017

Airway pathological heterogeneity in asthma: Visualization of disease microclusters using topological data analysis

scientific article published on 7 March 2018

Alternative Splicing Is a Major Factor Shaping Transcriptome Diversity in Mild and Severe Chronic Obstructive Pulmonary Disease

scientific article published in 2024

Angiotensin II induces histomorphologic features of unstable plaque in a murine model of accelerated atherosclerosis

scientific article published on 01 August 2006

Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation.

scientific article

Disconnect between sputum neutrophils and other measures of airway inflammation in asthma

scientific article published on 31 October 2013

Exacerbation Profile and Risk Factors in a Type-2–Low Enriched Severe Asthma Cohort: A Clinical Trial to Assess Asthma Exacerbation Phenotypes

scientific article published in 2022

Exploring the effects of omalizumab in allergic asthma: an analysis of biomarkers in the EXTRA study

scientific article published in April 2013

Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways

scientific article published on 27 December 2010

Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma.

scientific article published on 8 December 2011

IL-13 mediates IL-33-dependent mast cell and type 2 innate lymphoid cell effects on bronchial epithelial cells.

scientific article published on 14 March 2015

Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma.

scientific article published on 8 November 2013

Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma

scientific article published on 5 October 2011

Inhibition of Rho-kinase by fasudil attenuated angiotensin II-induced cardiac hypertrophy in apolipoprotein E deficient mice.

scientific article

Interleukin-18 has antipermeablity and antiangiogenic activities in the eye: reciprocal suppression with VEGF.

scientific article

Lung gene expression in a rhesus allergic asthma model correlates with physiologic parameters of disease and exhibits common and distinct pathways with human asthma and a mouse asthma model

scientific article

Noninvasive biomarkers that predict treatment benefit from biologic therapies in asthma.

scientific article published on December 2013

Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients

scientific article published on August 2012

Ranibizumab for macular edema due to retinal vein occlusions: implication of VEGF as a critical stimulator.

scientific article published on 5 February 2008

Reduced epithelial suppressor of cytokine signalling 1 in severe eosinophilic asthma.

scientific article published on 23 June 2016

Research in progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK)

scientific article (publication date: February 2016)

Seasonal variability of lung function and Asthma Quality of Life Questionnaire Scores in adults with uncontrolled asthma

scientific article published on 11 November 2019

Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics.

scientific article

T-helper type 2-driven inflammation defines major subphenotypes of asthma.

scientific article published on 29 May 2009

TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma.

scientific article published on August 2015

The effects of lebrikizumab in patients with mild asthma following whole lung allergen challenge.

scientific article

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