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List of works by Suzanne M Cutts

A gel mobility shift assay for probing the effect of drug-DNA adducts on DNA-binding proteins.

scientific article published on January 1997

A molecular understanding of mitoxantrone-DNA adduct formation: effect of cytosine methylation and flanking sequences

scientific article published on 12 February 2004

A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo

scientific article

ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin-DNA adducts

scientific article published on 6 September 2009

Activation of DNA damage response pathways as a consequence of anthracycline-DNA adduct formation

scientific article

Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate

scientific article published on April 2007

An oligonucleotide crosslinking assay for the analysis of individual drug-binding sites.

scientific article published on January 1997

Anthracyclines ⬇️

scholarly article

Barminomycin functions as a potent pre-activated analogue of Adriamycin ⬇️

scientific article published on November 28, 2001

Binding of pixantrone to DNA at CpA dinucleotide sequences and bulge structures

scientific article published on June 2015

Cloning, expression, and promoter structure of a mammalian inner centromere protein (INCENP).

scientific article published in April 1999

Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation.

scientific article published in May 2001

CpG methylation potentiates pixantrone and doxorubicin-induced DNA damage and is a marker of drug sensitivity

scientific article published on 31 August 2009

DNA binding by pixantrone

scientific article

DNA repair in response to anthracycline-DNA adducts: a role for both homologous recombination and nucleotide excision repair.

scientific article published on 16 September 2007

Design, synthesis, and DNA sequence selectivity of formaldehyde-mediated DNA-adducts of the novel N -(4-aminobutyl) acridine-4-carboxamide

scientific article published on 23 October 2014

Detection of Adriamycin-DNA adducts by accelerator mass spectrometry at clinically relevant Adriamycin concentrations

scientific article published on 16 July 2008

Detection of adriamycin-DNA adducts by accelerator mass spectrometry

scientific article

Development of pluronic micelle-encapsulated doxorubicin and formaldehyde-releasing prodrugs for localized anticancer chemotherapy

scientific article published on 01 January 2009

Disparate impact of butyroyloxymethyl diethylphosphate (AN-7), a histone deacetylase inhibitor, and doxorubicin in mice bearing a mammary tumor

scientific article

Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death

scientific article

Effects of histone deacetylase inhibitory prodrugs on epigenetic changes and DNA damage response in tumor and heart of glioblastoma xenograft

scientific article published on 17 March 2017

Encapsulation of Mitoxantrone within Cucurbit[8]uril Decreases Toxicity and Enhances Survival in a Mouse Model of Cancer

scientific article

Erratum: Factors determining the stability, size distribution, and cellular accumulation of small, monodisperse chitosan nanoparticles as candidate vectors for anticancer drug delivery: application to the passive encapsulation of [(14)C]-doxorubicin

scholarly article published in Nanotechnology, Science and Applications

Factors determining the stability, size distribution, and cellular accumulation of small, monodisperse chitosan nanoparticles as candidate vectors for anticancer drug delivery: application to the passive encapsulation of [(14)C]-doxorubicin

scientific article

Formaldehyde-activated Pixantrone is a monofunctional DNA alkylator that binds selectively to CpG and CpA doublets

scientific article published on 15 April 2008

Formaldehyde-releasing prodrugs specifically affect cancer cells by depletion of intracellular glutathione and augmentation of reactive oxygen species

scientific article published on 21 November 2007

Formation of adriamycin--DNA adducts in vitro.

scientific article published on June 1994

High-resolution transcription assay for probing drug-DNA interactions at individual drug sites

scientific article published on 01 January 2001

In vitro transcription assay for resolution of drug-DNA interactions at defined DNA sequences

scientific article published in January 2010

In vivo and in vitro antitumor activity of butyroyloxymethyl-diethyl phosphate (AN-7), a histone deacetylase inhibitor, in human prostate cancer

scientific article published in August 2005

Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells

scientific article published on 15 April 2015

Interstrand cross-linking by adriamycin in nuclear and mitochondrial DNA of MCF-7 cells

scientific article

Isolation and structural analysis of the covalent adduct formed between a bis-amino mitoxantrone analogue and DNA: a pathway to major-minor groove cross-linked adducts

scientific article published on 13 October 2016

M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe

scientific article

Mitoxantrone mediates demethylation and reexpression of cyclin d2, estrogen receptor and 14.3.3sigma in breast cancer cells.

scientific article published in May 2003

Mitoxantrone, More than Just Another Topoisomerase II Poison.

scientific article published on 19 August 2015

Mode of interaction between butyroyloxymethyl-diethyl phosphate (AN-7) and doxorubicin in MCF-7 and resistant MCF-7/Dx cell lines

scientific article published on 7 July 2006

New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation

scientific article published on October 2010

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

scientific article

Potential Therapeutic Advantages of Doxorubicin when Activated by Formaldehyde to Function as a DNA Adduct-Forming Agent

scientific article published on 13 April 2015

Processing of anthracycline-DNA adducts via DNA replication and interstrand crosslink repair pathways

scientific article published on 2 February 2012

Recent advances in understanding and exploiting the activation of anthracyclines by formaldehyde.

scientific article

Reversible and formaldehyde-mediated covalent binding of a bis-amino mitoxantrone analogue to DNA.

scientific article published on 4 May 2016

The cardio-protecting agent and topoisomerase II catalytic inhibitor sobuzoxane enhances doxorubicin-DNA adduct mediated cytotoxicity

scientific article published on 27 June 2007

The histone deacetylase inhibitor butyroyloxymethyl diethylphosphate (AN-7) protects normal cells against toxicity of anticancer agents while augmenting their anticancer activity

scientific article published on 23 September 2010

The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts

scientific article

The power and potential of doxorubicin-DNA adducts

scientific article

The role of intracellularly released formaldehyde and butyric acid in the anticancer activity of acyloxyalkyl esters.

scientific article published on February 2005

The selectivty and anti-metastatic activity of oral bioavailable butyric acid prodrugs

scientific article published on September 2006

ToF-SIMS and Machine Learning for Single-Pixel Molecular Discrimination of an Acrylate Polymer Microarray

scientific article published on 13 April 2020

Use of oligonucleotides to define the site of interstrand cross-links induced by Adriamycin.

scientific article

Visualizing ToF-SIMS Hyperspectral Imaging Data Using Color-Tagged Toroidal Self-Organizing Maps

scientific article published on 07 October 2019

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