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List of works by Jean-Christophe Jonas

Acute nutrient regulation of the mitochondrial glutathione redox state in pancreatic β-cells

scientific article published in June 2014

Acute nutrient regulation of the unfolded protein response and integrated stress response in cultured rat pancreatic islets

scientific article published on 12 May 2007

Antioxidants N-acetyl-L-cysteine and manganese(III)tetrakis (4-benzoic acid)porphyrin do not prevent beta-cell dysfunction in rat islets cultured in high glucose for 1 wk.

scientific article published on 7 February 2006

Atypical Ca2+-induced Ca2+ release from a sarco-endoplasmic reticulum Ca2+-ATPase 3-dependent Ca2+ pool in mouse pancreatic beta-cells.

scientific article

Biomarkers of tumour redox status in response to modulations of glutathione and thioredoxin antioxidant pathways

scientific article published on 10 January 2018

Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes

scientific article published on 01 May 1999

Clonidine inhibits ATP-sensitive K+ channels in mouse pancreatic beta-cells.

scientific article published in October 1991

Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations.

scientific article published on 23 January 2009

Culture duration and conditions affect the oscillations of cytoplasmic calcium concentration induced by glucose in mouse pancreatic islets

scientific article published on 01 October 1994

Dynamic measurements of mitochondrial hydrogen peroxide concentration and glutathione redox state in rat pancreatic β-cells using ratiometric fluorescent proteins: confounding effects of pH with HyPer but not roGFP1.

scientific article published in February 2012

Dynamics of Ca2+ and guanosine 5'-[gamma-thio]triphosphate action on insulin secretion from alpha-toxin-permeabilized HIT-T15 cells.

scientific article published on July 1994

Effects of c-MYC activation on glucose stimulus-secretion coupling events in mouse pancreatic islets.

scientific article published on 15 April 2008

Endoplasmic reticulum accumulation of Kir6.2 without activation of ER stress response in islet cells from adult Sur1 knockout mice

scientific article published on 6 April 2010

Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia

scientific article published on 30 January 2020

Expression of Ca(2+) Transport Genes in Platelets and Endothelial Cells in Hypertension

scientific article published on 01 January 2001

Glucokinase activation is beneficial or toxic to cultured rat pancreatic islets depending on the prevailing glucose concentration

scientific article

Glucolipotoxic conditions induce β-cell iron import, cytosolic ROS formation and apoptosis

scientific article published on 01 August 2018

Glucose regulation of islet stress responses and beta-cell failure in type 2 diabetes.

scientific article

Glucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells

scientific article (publication date: 2012)

HDLs protect pancreatic β-cells against ER stress by restoring protein folding and trafficking

scientific article published on 7 March 2012

Hierarchy of the beta-cell signals controlling insulin secretion.

scientific article

Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.

scientific article published on 04 April 2016

Identification and subcellular localization of the Na+/H+ exchanger and a novel related protein in the endocrine pancreas and adrenal medulla

scientific article published on 01 March 2007

In vitro stimulation of insulin release by SL 84.0418, a new alpha 2-adrenoceptor antagonist.

scientific article published in March 1994

Induction of adiponectin in skeletal muscle by inflammatory cytokines: in vivo and in vitro studies.

scientific article

Influence of cell number on the characteristics and synchrony of Ca2+ oscillations in clusters of mouse pancreatic islet cells

scientific article published on 01 November 1999

Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide

scientific article published on 01 October 2020

Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3.

scientific article

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

scientific article

Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions

scientific article published on 4 December 2017

Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans

scientific article published on 17 October 2019

MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity

scientific article

Mitochondrial regulation of insulin production in rat pancreatic islets.

scientific article published on 29 June 2005

NADPH oxidase-2 does not contribute to β-cell glucotoxicity in cultured pancreatic islets from C57BL/6J mice

scientific article published on 21 September 2016

NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells

scientific article

Nutrient Metabolism, Subcellular Redox State, and Oxidative Stress in Pancreatic Islets and β-Cells

scientific article published on 18 October 2019

Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes

Phlda3 regulates beta cell survival during stress

scientific article published on 06 September 2019

Prenylcysteine analogs mimicking the C-terminus of GTP-binding proteins stimulate exocytosis from permeabilized HIT-T15 cells: comparison with the effect of Rab3AL peptide.

scientific article

Probe-independent and direct quantification of insulin mRNA and growth hormone mRNA in enriched cell preparations.

scientific article published in December 2006

Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.

scientific article published on December 2003

Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped

scientific article published in 2022

Protective antioxidant and antiapoptotic effects of ZnCl2 in rat pancreatic islets cultured in low and high glucose concentrations

scientific article

Role of activating transcription factor 3 in low glucose- and thapsigargin-induced apoptosis in cultured mouse islets

scientific article published on 18 October 2011

SERCA3 ablation does not impair insulin secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca(2+) pumps for Ca(2+) homeostasis in pancreatic beta-cells.

scientific article

Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of KATP Channel Blockers

scientific article published on 16 August 2018

Stable and diffusible pools of nucleotides in pancreatic islet cells

scientific article published on 01 November 1996

Sulphonylureas do not increase insulin secretion by a mechanism other than a rise in cytoplasmic Ca2+ in pancreatic B-cells

scientific article published on 01 March 1996

The imidazoline SL 84.0418 shows stereoselectivity in blocking alpha 2-adrenoceptors but not ATP-sensitive K+ channels in pancreatic B-cells

scientific article published on 01 October 1994

The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.

scientific article published on 03 February 2014

The molecular mechanisms of pancreatic β-cell glucotoxicity: Recent findings and future research directions ⬇️

scientific article published on August 10, 2012

Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia

scientific article

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