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List of works by Neale D. Ridgway

19q13.12 microdeletion syndrome fibroblasts display abnormal storage of cholesterol and sphingolipids in the endo-lysosomal system.

scientific article published on 23 March 2018

A Lipid Transfer Protein Signaling Axis Exerts Dual Control of Cell-Cycle and Membrane Trafficking Systems.

scientific article published on 26 January 2018

A mechanism for suppression of the CDP-choline pathway during apoptosis

scientific article published on 17 October 2013

Altered regulation of cholesterol and cholesteryl ester synthesis in Chinese-hamster ovary cells overexpressing the oxysterol-binding protein is dependent on the pleckstrin homology domain ⬇️

scientific article published on August 15, 1997

Analysis of Sphingolipid Synthesis and Transport by Metabolic Labeling of Cultured Cells with [³H]Serine

scientific article published in January 2016

Aromatic boronic acids as probes of the catalytic site of human plasma lecithin-cholesterol acyltransferase

scientific article

Brefeldin A renders Chinese hamster ovary cells insensitive to transcriptional suppression by 25-hydroxycholesterol.

scientific article published on April 1995

Bridging the molecular and biological functions of the oxysterol-binding protein family

scientific article published on 13 March 2018

CTP:phosphocholine cytidylyltransferase α (CCTα) and lamins alter nuclear membrane structure without affecting phosphatidylcholine synthesis

scientific article published on 9 April 2011

CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis

scientific article published on 09 July 2015

Characterization of the sterol and phosphatidylinositol 4-phosphate binding properties of Golgi-associated OSBP-related protein 9 (ORP9)

scientific article

Curcumin-induced apoptosis in PC3 prostate carcinoma cells is caspase-independent and involves cellular ceramide accumulation and damage to mitochondria.

scientific article

Differential effects of sphingomyelin hydrolysis and cholesterol transport on oxysterol-binding protein phosphorylation and Golgi localization

scientific article published on 01 November 1998

Effect of fumonisin B1 on phosphatidylethanolamine biosynthesis in Chinese hamster ovary cells

scientific article published on 01 December 1996

Expansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha.

scientific article

Functional implications of sterol transport by the oxysterol-binding protein gene family.

scientific article published on July 2010

Golgi localization of oxysterol binding protein-related protein 4L (ORP4L) is regulated by ligand binding

scientific article published on 19 July 2018

How CCTα puts a leash on phospholipid synthesis.

scientific article published in May 2018

In vitro phosphorylation of phosphatidylethanolamine N-methyltransferase by cAMP-dependent protein kinase: lack of in vivo phosphorylation in response to N6-2'-O-dibutryladenosine 3',5'-cyclic monophosphate

scientific article published on 01 August 1989

Induction of apoptosis by lipophilic activators of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha).

scientific article published on December 2005

Induction of protein kinase C substrates, Myristoylated alanine-rich C kinase substrate (MARCKS) and MARCKS-related protein (MRP), by amyloid beta-protein in mouse BV-2 microglial cells

scientific article published in August 2003

Inhibition of HCV replication by oxysterol-binding protein-related protein 4 (ORP4) through interaction with HCV NS5B and alteration of lipid droplet formation

scientific article

Inhibition of acyl-CoA:cholesterol acyltransferase in Chinese hamster ovary (CHO) cells by short-chain ceramide and dihydroceramide

scientific article published in April 1995

Inhibition of phosphorylation of the oxysterol binding protein by brefeldin A.

scientific article published in February 1998

Inhibitors of actin polymerization and calmodulin binding enhance protein kinase C-induced translocation of MARCKS in C6 glioma cells

scientific article published in April 1997

Involvement of phospholipase D and protein kinase C in phorbol ester and fatty acid stimulated turnover of phosphatidylcholine and phosphatidylethanolamine in neural cells ⬇️

scientific article published on February 5, 1998

Lipid-associated PML structures assemble nuclear lipid droplets containing CCTα and Lipin1

scientific article published on 27 May 2020

Lipoprotein lipase-mediated sequestration of long-chain polyunsaturated triacylglycerols in serum LDL from normal and hypothyroid rats

scientific article published on 01 October 1984

Metabolism of short-chain ceramide and dihydroceramide analogues in Chinese hamster ovary (CHO) cells

scientific article published in April 1995

Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis.

scientific article published on 8 August 2012

Myristoylated alanine-rich C-kinase substrate is phosphorylated and translocated by a phorbol ester-insensitive and calcium-independent protein kinase C isoform in C6 glioma cell membranes.

scientific article published on January 1999

Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport

scientific article

Nuclear export of the rate-limiting enzyme in phosphatidylcholine synthesis is mediated by its membrane binding domain.

scientific article

Nuclear-localized CTP:phosphocholine cytidylyltransferase α regulates phosphatidylcholine synthesis required for lipid droplet biogenesis

scientific article

OSBP negatively regulates ABCA1 protein stability

scientific article published in May 2008

Oxysterol activation of phosphatidylcholine synthesis involves CTP:phosphocholine cytidylyltransferase alpha translocation to the nuclear envelope.

scientific article

Oxysterol binding protein-dependent activation of sphingomyelin synthesis in the golgi apparatus requires phosphatidylinositol 4-kinase IIα.

scientific article

Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function

scientific article

Oxysterol-Binding Protein-Related Protein 1L Regulates Cholesterol Egress from the Endo-Lysosomal System

scientific article published in May 2017

Oxysterol-binding Protein Activation at Endoplasmic Reticulum-Golgi Contact Sites Reorganizes Phosphatidylinositol 4-Phosphate Pools

scientific article published on 23 November 2015

Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival

scientific article published on 16 April 2014

Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein

scientific article

Oxysterol-binding protein recruitment and activity at the endoplasmic reticulum-Golgi interface are independent of Sac1.

scientific article published on 4 May 2017

Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 substrate and regulates Akt phosphorylation.

scientific article

Oxysterol-binding proteins.

scientific article

Phosphatidylcholine synthesis influences the diacylglycerol homeostasis required for SEC14p-dependent Golgi function and cell growth

scientific article published on March 2001

Phosphatidylcholine synthesis regulates triglyceride storage and chylomicron secretion by Caco2 cells

scientific article published on 16 August 2018

Phosphatidylethanolamine N-methyltransferase from rat liver

scientific article published on 01 January 1992

Phospholipase D activity is altered in X-linked adrenoleukodystrophy heterozygous carriers, but not in hemizygous patients

scientific article published in July 1998

Phospholipase D hydrolysis of plasmalogen and diacyl ethanolamine phosphoglycerides by protein kinase C dependent and independent mechanisms.

scientific article published in January 1997

Phosphorylation of a serine/proline-rich motif in oxysterol binding protein-related protein 4L (ORP4L) regulates cholesterol and vimentin binding

scientific article published on 29 March 2019

Preferential externalization of newly synthesized phosphatidylserine in apoptotic U937 cells is dependent on caspase-mediated pathways

scientific article published on 01 September 2000

Progesterone metabolism in human fibroblasts is independent of P-glycoprotein levels and Niemann-Pick type C disease

scientific article

Protein kinase C isoforms and growth, differentiation and phosphatidylcholine turnover in human neuroblastoma cells.

scientific article published in September 1996

Protein kinase D1 and oxysterol-binding protein form a regulatory complex independent of phosphorylation

scientific article published on 11 September 2018

Regulation of intracellular cholesterol metabolism is defective in lymphoblasts from Niemann-Pick type C and type D patients.

scientific article published on May 1994

Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation

scientific article

Regulation of phosphatidylcholine metabolism in Chinese hamster ovary cells by the sterol regulatory element-binding protein (SREBP)/SREBP cleavage-activating protein pathway

scientific article published on 01 May 2000

Regulation of the CDP-choline pathway by sterol regulatory element binding proteins involves transcriptional and post-transcriptional mechanisms.

scientific article

Resistance to UV-induced apoptosis in Chinese-hamster ovary cells overexpressing phosphatidylserine synthases.

scientific article published on August 2004

Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine

scientific article published on 2 November 2016

Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1

scientific journal article

The role of de novo ceramide synthesis in the mechanism of action of the tricyclic xanthate D609.

scientific article published on 16 September 2003

The role of phosphatidylcholine and choline metabolites to cell proliferation and survival.

scientific article published on January 2013

The role of phospholipids in the biological activity and structure of the endoplasmic reticulum

scientific article

U18666A inhibits intracellular cholesterol transport and neurotransmitter release in human neuroblastoma cells

scientific article published on 01 January 1999

VAMP-associated protein-A regulates partitioning of oxysterol-binding protein-related protein-9 between the endoplasmic reticulum and Golgi apparatus.

scientific article

Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum.

scientific article

cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19

scientific article

ras-Induced up-regulation of CTP:phosphocholine cytidylyltransferase α contributes to malignant transformation of intestinal epithelial cells.

scientific article published on 15 November 2012

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