List of works - Aya Tanatani

4-(Anilino)pyrrole-2-carboxamides: Novel non-steroidal/non-anilide type androgen antagonists effective upon human prostate tumor LNCaP cells with mutated nuclear androgen receptor

scientific article

6-arylcoumarins as novel nonsteroidal type progesterone antagonists: an example with receptor-binding-dependent fluorescence

scientific article published on 5 October 2011

A chiral N-methylbenzamide: Spontaneous generation of optical activity

A layered artificial dinucleotide complex

Absolute Helical Arrangement of Sulfonamide in the Crystal

scientific article published on 01 October 2003

Absolute helical arrangement of stacked benzene rings: heterogeneous double-helical interaction comprising a hydrogen-bonding belt and an offset parallel aromatic-aromatic-interaction array

scientific article published in March 2004

Amide Conformational Switching Induced by Protonation of Aromatic Substituent

scientific article published on 01 April 2003

Anti-androgens with full antagonistic activity toward human prostate tumor LNCaP cells with mutated androgen receptor

scientific article published in August 2003

Aromatic β-sheet foldamers based on tertiary squaramides

scientific article published on 01 August 2019

Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carborane

scientific article

Calix[3]amide-based anion receptors: high affinity for fluoride ions and a twisted binding model

Chain length-dependent affinity of helical foldamers for a rodlike guest

scientific article published in February 2001

Conformational Properties of Aromatic Oligoamides Bearing Pyrrole Rings

scientific article published on 11 April 2018

Conformational and Chiral Properties of Cyclic-tri(N-methyl-meta-benzamide) Bearing Amidino Groups

scientific article published on 24 June 2015

Conformational properties of aromatic multi-layered and helical oligoureas and oligoguanidines

Cyclic-tri(N-methyl-meta-benzamide)s: substituent effects on the bowl-shaped conformation in the crystal and solution states

Cyclooxygenase inhibitors derived from thalidomide

scientific article (publication date: September 2003)

Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists.

scientific article published on 6 August 2015

Design and synthesis of subtype-selective cyclooxygenase (COX) inhibitors derived from thalidomide.

scientific article

Design and synthesis of tetraol derivatives of 1,12-dicarba- closo -dodecaborane as non-secosteroidal vitamin D analogs

scientific article published on 06 August 2014

Development of 1,3-diphenyladamantane derivatives as nonsteroidal progesterone receptor antagonists.

scientific article

Development of 6-arylcoumarins as nonsteroidal progesterone antagonists. Structure-activity relationships and fluorescence properties.

scientific article published on 12 September 2016

Development of Androgen-Antagonistic Coumarinamides with a Unique Aromatic Folded Pharmacophore

scientific article published on 04 August 2020

Development of Helical Aromatic Amide Foldamers with a Diphenylacetylene Backbone

scientific article published on 17 January 2020

Development of N-(4-Phenoxyphenyl)benzenesulfonamide Derivatives as Novel Nonsteroidal Progesterone Receptor Antagonists

scientific article published on 15 September 2016

Development of Novel Nuclear Receptor Ligands Based on Receptor-Folding Inhibition Hypothesis

article

Development of bis-thiourea-type organocatalyst for asymmetric Baylis–Hillman reaction

article

Development of novel chiral urea catalysts for the hetero-Michael reaction.

scientific article published in April 2004

Development of novel lithocholic acid derivatives as vitamin D receptor agonists

scientific article published on 03 July 2019

Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: Preparation of FXR and PPAR ligands

scientific article published on 17 April 2006

Enantioselective Total Synthesis of Batzelladine A

scientific article published on 01 March 2004

Fluorescent visualization of the conformational change of aromatic amide or urea induced by N-methylation

Foldamers as dynamic receptors: probing the mechanism of molecular association between helical oligomers and rodlike ligands

scientific article published on 01 January 2002

Folding of a linear array of α-amino acids within a helical aromatic oligoamide frame.

scientific article published on 24 June 2013

Frustrated Helicity: Joining the Diverging Ends of a Stable Aromatic Amide Helix to Form a Fluxional Macrocycle.

scientific article published on 14 April 2018

Helical Folding of Poly(naphthalenecarboxamide) Prompted by Solvophobic Effect

Helical aromatic urea and guanidine

Helical structures of N-alkylated poly(p-benzamide)s.

scientific article published in June 2005

Identification of absolute helical structures of aromatic multilayered oligo(m-phenylurea)s in solution.

scientific article published in November 2009

Ligands with a 3,3-diphenylpentane skeleton for nuclear vitamin D and androgen receptors: Dual activities and metabolic activation

scientific article published on 15 May 2006

Ligands with dual vitamin D3-agonistic and androgen-antagonistic activities

scientific article published in October 2005

Lipase-catalyzed asymmetric acylation of boron cluster-containing secondary alcohols

Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists

scientific article published on 28 December 2020

Molecular chirality and chiral capsule-type dimer formation of cyclic triamidesvia hydrogen-bonding interactions

scientific article published on 05 March 2012

Molecular construction based on icosahedral carboranes and aromatic N,N′-dimethylurea groups. Aromatic layered molecules and a transition metal complex

Molecular construction based on icosahedral carboranes and aromatic urea groups. A new type of carboracycle

article published in 2001

N-Methylated Diphenylguanidines: Conformations, Propeller-Type Molecular Chirality, and Construction of Water-Soluble Oligomers with Multilayered Aromatic Structures

scientific article published in 1998

N-phenylphthalimide-type cyclooxygenase (COX) inhibitors derived from thalidomide: substituent effects on subtype selectivity.

scientific article

Novel Non-steroidal Progesterone Receptor Ligands Based on m-Carborane Containing a Secondary Alcohol: Effect of Chirality on Ligand Activity.

scientific article published in January 2017

Novel non-steroidal/non-anilide type androgen antagonists: discovery of 4-substituted pyrrole-2-carboxamides as a new scaffold for androgen receptor ligands

scientific article

Novel vitamin D receptor ligands bearing a spherical hydrophobic core structure—Comparison of bicyclic hydrocarbon derivatives with boron cluster derivatives

scientific article published on 10 January 2012

Nuclear Receptor Drug Discovery

Phenylhomophthalimide-type NOS inhibitors derived from thalidomide.

scientific article

Practical Synthesis and Evaluation of the Biological Activities of 1α,25-dihydroxyvitamin D3Antagonists, 1α,25-dihydroxyvitamin D3-26,23-lactams. Designed on the Basis of the Helix 12-Folding Inhibition Hypothesis

scientific article published on 01 April 2006

Redox-Induced Conformational Alteration ofN,N-Diarylamides

scientific article published on 16 November 2007

Redox-responsive conformational alteration of aromatic amides bearing N-quinonyl system

Solid-Phase Synthesis of Water-Soluble Helically Folded Hybrid α-Amino Acid/Quinoline Oligoamides

scientific article

Solvent-Dependent Conformational Switching ofN-Phenylhydroxamic Acid and Its Application in Crystal Engineering

Solvent-dependent conformational and fluorescence change of an N-phenylbenzohydroxamic acid derivative bearing two pyrene moieties

Specific nonpeptide inhibitors of puromycin-sensitive aminopeptidase with a 2,4(1H,3H)-quinazolinedione skeleton.

scientific article published on November 2003

Spontaneous Resolution of Aromatic Sulfonamides: Effective Screening Method and Discrimination of Absolute Structure

scientific article published on 01 October 2006

Steric structure-activity relationship of cyproheptadine derivatives as inhibitors of histone methyltransferase Set7/9.

scientific article published on 12 July 2016

Structural development of p-carborane-based potent non-secosteroidal vitamin D analogs

scientific article published on 16 September 2014

Structural elucidation of foldamers with no long range conformational order

scientific article published on 01 September 2014

Structure-activity relationship of novel (benzoylaminophenoxy)phenol derivatives as anti-prostate cancer agents

scientific article published on 06 September 2018

Synthesis and Conformational Analysis of Alternately N-Alkylated Aromatic Amide Oligomers

scientific article published on 15 November 2018

Synthesis and Conformational Analysis of Quinoline-Oxazole Peptides

Synthesis and helical properties of aromatic multilayered oligoureas

Synthesis and structure–activity relationship of p-carborane-based non-secosteroidal vitamin D analogs

scientific article published on 21 January 2014

Synthesis of 1alpha,25-dihydroxyvitamin D3-26,23-lactams (DLAMs), a novel series of 1 alpha,25-dihydroxyvitamin D3 antagonist.

scientific article published in May 2004

Synthesis of 1α,25-dihydroxyvitamin D3-26,23-lactams (DLAMs), a novel series of 1α,25-dihydroxyvitamin D3 antagonist

scholarly article by Yuko Kato et al published May 2004 in Bioorganic & Medicinal Chemistry Letters

Synthesis of porphyrinylamide and observation of N-methylation-induced trans–cis amide conformational alteration

Synthesis of soluble aromatic multilayered tetra(m-phenylurea) and analysis of its helical conformation in various solvents.

scientific article

Thalidomide as a nitric oxide synthase inhibitor and its structural development

scientific article published in April 2004

The size-selective synthesis of folded oligomers by dynamic templation

scientific article published in May 2002

Total synthesis of (+)-batzelladine A and (-)-batzelladine D, and identification of their target protein.

scientific article

Unusual conformational preference of an aromatic secondary urea: solvent-dependent open-closed conformational switching of N,N'-bis(porphyrinyl)urea

scientific article published in March 2013

Update on recent progress in vitamin D research. Development of novel Vitamin D Derivatives

scientific article published in January 2017

[Novel Helical Foldamers Based on the Conformational Properties of Aromatic Amides]

scientific article published on 01 January 2019

List of works by Aya Tanatani

4-(Anilino)pyrrole-2-carboxamides: Novel non-steroidal/non-anilide type androgen antagonists effective upon human prostate tumor LNCaP cells with mutated nuclear androgen receptor

6-arylcoumarins as novel nonsteroidal type progesterone antagonists: an example with receptor-binding-dependent fluorescence

A chiral N-methylbenzamide: Spontaneous generation of optical activity

A layered artificial dinucleotide complex

Absolute Helical Arrangement of Sulfonamide in the Crystal

Absolute helical arrangement of stacked benzene rings: heterogeneous double-helical interaction comprising a hydrogen-bonding belt and an offset parallel aromatic-aromatic-interaction array

Amide Conformational Switching Induced by Protonation of Aromatic Substituent

Anti-androgens with full antagonistic activity toward human prostate tumor LNCaP cells with mutated androgen receptor

Aromatic β-sheet foldamers based on tertiary squaramides

Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carborane

Calix[3]amide-based anion receptors: high affinity for fluoride ions and a twisted binding model

Chain length-dependent affinity of helical foldamers for a rodlike guest

Conformational Properties of Aromatic Oligoamides Bearing Pyrrole Rings

Conformational and Chiral Properties of Cyclic-tri(N-methyl-meta-benzamide) Bearing Amidino Groups

Conformational properties of aromatic multi-layered and helical oligoureas and oligoguanidines

Cyclic-tri(N-methyl-meta-benzamide)s: substituent effects on the bowl-shaped conformation in the crystal and solution states

Cyclooxygenase inhibitors derived from thalidomide

Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists.

Design and synthesis of subtype-selective cyclooxygenase (COX) inhibitors derived from thalidomide.

Design and synthesis of tetraol derivatives of 1,12-dicarba- closo -dodecaborane as non-secosteroidal vitamin D analogs

Development of 1,3-diphenyladamantane derivatives as nonsteroidal progesterone receptor antagonists.

Development of 6-arylcoumarins as nonsteroidal progesterone antagonists. Structure-activity relationships and fluorescence properties.

Development of Androgen-Antagonistic Coumarinamides with a Unique Aromatic Folded Pharmacophore

Development of Helical Aromatic Amide Foldamers with a Diphenylacetylene Backbone

Development of N-(4-Phenoxyphenyl)benzenesulfonamide Derivatives as Novel Nonsteroidal Progesterone Receptor Antagonists

Development of Novel Nuclear Receptor Ligands Based on Receptor-Folding Inhibition Hypothesis

Development of bis-thiourea-type organocatalyst for asymmetric Baylis–Hillman reaction

Development of novel chiral urea catalysts for the hetero-Michael reaction.

Development of novel lithocholic acid derivatives as vitamin D receptor agonists

Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: Preparation of FXR and PPAR ligands

Enantioselective Total Synthesis of Batzelladine A

Fluorescent visualization of the conformational change of aromatic amide or urea induced by N-methylation

Foldamers as dynamic receptors: probing the mechanism of molecular association between helical oligomers and rodlike ligands

Folding of a linear array of α-amino acids within a helical aromatic oligoamide frame.

Frustrated Helicity: Joining the Diverging Ends of a Stable Aromatic Amide Helix to Form a Fluxional Macrocycle.

Helical Folding of Poly(naphthalenecarboxamide) Prompted by Solvophobic Effect

Helical aromatic urea and guanidine

Helical structures of N-alkylated poly(p-benzamide)s.

Identification of absolute helical structures of aromatic multilayered oligo(m-phenylurea)s in solution.

Ligands with a 3,3-diphenylpentane skeleton for nuclear vitamin D and androgen receptors: Dual activities and metabolic activation

Ligands with dual vitamin D3-agonistic and androgen-antagonistic activities

Lipase-catalyzed asymmetric acylation of boron cluster-containing secondary alcohols

Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists

Molecular chirality and chiral capsule-type dimer formation of cyclic triamidesvia hydrogen-bonding interactions

Molecular construction based on icosahedral carboranes and aromatic N,N′-dimethylurea groups. Aromatic layered molecules and a transition metal complex

Molecular construction based on icosahedral carboranes and aromatic urea groups. A new type of carboracycle

N-Methylated Diphenylguanidines: Conformations, Propeller-Type Molecular Chirality, and Construction of Water-Soluble Oligomers with Multilayered Aromatic Structures

N-phenylphthalimide-type cyclooxygenase (COX) inhibitors derived from thalidomide: substituent effects on subtype selectivity.

Novel Non-steroidal Progesterone Receptor Ligands Based on m-Carborane Containing a Secondary Alcohol: Effect of Chirality on Ligand Activity.

Novel non-steroidal/non-anilide type androgen antagonists: discovery of 4-substituted pyrrole-2-carboxamides as a new scaffold for androgen receptor ligands

Novel vitamin D receptor ligands bearing a spherical hydrophobic core structure—Comparison of bicyclic hydrocarbon derivatives with boron cluster derivatives

Nuclear Receptor Drug Discovery

Phenylhomophthalimide-type NOS inhibitors derived from thalidomide.

Practical Synthesis and Evaluation of the Biological Activities of 1α,25-dihydroxyvitamin D3Antagonists, 1α,25-dihydroxyvitamin D3-26,23-lactams. Designed on the Basis of the Helix 12-Folding Inhibition Hypothesis

Redox-Induced Conformational Alteration ofN,N-Diarylamides

Redox-responsive conformational alteration of aromatic amides bearing N-quinonyl system

Solid-Phase Synthesis of Water-Soluble Helically Folded Hybrid α-Amino Acid/Quinoline Oligoamides

Solvent-Dependent Conformational Switching ofN-Phenylhydroxamic Acid and Its Application in Crystal Engineering

Solvent-dependent conformational and fluorescence change of an N-phenylbenzohydroxamic acid derivative bearing two pyrene moieties

Specific nonpeptide inhibitors of puromycin-sensitive aminopeptidase with a 2,4(1H,3H)-quinazolinedione skeleton.

Spontaneous Resolution of Aromatic Sulfonamides: Effective Screening Method and Discrimination of Absolute Structure

Steric structure-activity relationship of cyproheptadine derivatives as inhibitors of histone methyltransferase Set7/9.

Structural development of p-carborane-based potent non-secosteroidal vitamin D analogs

Structural elucidation of foldamers with no long range conformational order

Structure-activity relationship of novel (benzoylaminophenoxy)phenol derivatives as anti-prostate cancer agents

Synthesis and Conformational Analysis of Alternately N-Alkylated Aromatic Amide Oligomers

Synthesis and Conformational Analysis of Quinoline-Oxazole Peptides

Synthesis and helical properties of aromatic multilayered oligoureas

Synthesis and structure–activity relationship of p-carborane-based non-secosteroidal vitamin D analogs

Synthesis of 1alpha,25-dihydroxyvitamin D3-26,23-lactams (DLAMs), a novel series of 1 alpha,25-dihydroxyvitamin D3 antagonist.

Synthesis of 1α,25-dihydroxyvitamin D3-26,23-lactams (DLAMs), a novel series of 1α,25-dihydroxyvitamin D3 antagonist

Synthesis of porphyrinylamide and observation of N-methylation-induced trans–cis amide conformational alteration

Synthesis of soluble aromatic multilayered tetra(m-phenylurea) and analysis of its helical conformation in various solvents.

Thalidomide as a nitric oxide synthase inhibitor and its structural development

The size-selective synthesis of folded oligomers by dynamic templation

Total synthesis of (+)-batzelladine A and (-)-batzelladine D, and identification of their target protein.

Unusual conformational preference of an aromatic secondary urea: solvent-dependent open-closed conformational switching of N,N'-bis(porphyrinyl)urea

Update on recent progress in vitamin D research. Development of novel Vitamin D Derivatives

[Novel Helical Foldamers Based on the Conformational Properties of Aromatic Amides]