List of works by Ana P. Silva

Acetyl-L-Carnitine Prevents Methamphetamine-Induced Structural Damage on Endothelial Cells via ILK-Related MMP-9 Activity

scientific article

Activation of neuropeptide Y receptors is neuroprotective against excitotoxicity in organotypic hippocampal slice cultures ⬇️

scientific article published on April 8, 2003

Ampakine CX546 increases proliferation and neuronal differentiation in subventricular zone stem/progenitor cell cultures.

scientific article published on 16 April 2012

Aquaporin-4 as a New Target against Methamphetamine-Induced Brain Alterations: Focus on the Neurogliovascular Unit and Motivational Behavior.

scientific article published on 10 March 2017

Brain injury associated with widely abused amphetamines: neuroinflammation, neurogenesis and blood-brain barrier.

scientific article published on December 2010

Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists.

scientific article published in September 1999

Effect of Hypoproteic and High-Fat Diets on Hippocampal Blood-Brain Barrier Permeability and Oxidative Stress

scientific article published on 01 January 2018

Effect of chronic methylphenidate treatment on hippocampal neurovascular unit and memory performance in late adolescent rats

scientific article published on 13 December 2018

Effects of drugs of abuse on the central neuropeptide Y system

scientific article published on 22 April 2015

Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis

scientific article published in September 2017

Extended-access methamphetamine self-administration elicits neuroinflammatory response along with blood-brain barrier breakdown.

scientific article

Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer's Disease.

scientific article

Impact of developmental exposure to methylphenidate on rat brain's immune privilege and behavior: Control versus ADHD model.

scientific article published on 20 October 2017

Inhibition of glutamate release by BIA 2-093 and BIA 2-024, two novel derivatives of carbamazepine, due to blockade of sodium but not calcium channels.

scientific article published in May 2001

Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia.

scientific article published in April 2008

Long-Term Treatment with Low Doses of Methamphetamine Promotes Neuronal Differentiation and Strengthens Long-Term Potentiation of Glutamatergic Synapses onto Dentate Granule Neurons.

scientific article published on May 2016

May exercise prevent addiction?

scientific article published on March 2011

Methamphetamine changes NMDA and AMPA glutamate receptor subunit levels in the rat striatum and frontal cortex

scientific article

Methamphetamine decreases dentate gyrus stem cell self-renewal and shifts the differentiation towards neuronal fate.

scientific article published on 13 August 2014

Methamphetamine exerts toxic effects on subventricular zone stem/progenitor cells and inhibits neuronal differentiation.

scientific article

Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory.

scientific article published on 26 September 2007

Methamphetamine transiently increases the blood-brain barrier permeability in the hippocampus: role of tight junction proteins and matrix metalloproteinase-9.

scientific article published on 14 July 2011

Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment.

scientific article published in November 2012

Methamphetamine-induced early increase of IL-6 and TNF-alpha mRNA expression in the mouse brain

scientific article

Methamphetamine-induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin.

scientific article published on 13 January 2010

Methamphetamine-induced nitric oxide promotes vesicular transport in blood-brain barrier endothelial cells.

scientific article published on September 2012

Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells

scientific article published on 4 July 2016

Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration

scientific article published on 01 June 2020

Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.

scientific article published in August 2003

Modulation of intracellular calcium changes and glutamate release by neuropeptide Y1 and Y2 receptors in the rat hippocampus: differential effects in CA1, CA3 and dentate gyrus.

scientific article published in October 2001

Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures.

scientific article published in July 2005

Neuropeptide Y as an endogenous antiepileptic, neuroprotective and pro-neurogenic peptide

scientific article

Neuropeptide Y can rescue neurons from cell death following the application of an excitotoxic insult with kainate in rat organotypic hippocampal slice cultures

scientific article published on 8 January 2007

Neuropeptide Y modulation of interleukin-1{beta} (IL-1{beta})-induced nitric oxide production in microglia.

scientific article

Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures

scientific article published on 22 February 2012

Neurotoxic/neuroprotective profile of carbamazepine, oxcarbazepine and two new putative antiepileptic drugs, BIA 2-093 and BIA 2-024

scientific article published on 01 October 2000

Presynaptic modulation controlling neuronal excitability and epileptogenesis: role of kainate, adenosine and neuropeptide Y receptors.

scientific article published on October 2003

Prevention of methamphetamine-induced microglial cell death by TNF-α and IL-6 through activation of the JAK-STAT pathway

scientific article published on 6 July 2012

Protective role of neuropeptide Y Y₂ receptors in cell death and microglial response following methamphetamine injury

scientific article

Protein kinase C activity blocks neuropeptide Y-mediated inhibition of glutamate release and contributes to excitability of the hippocampus in status epilepticus.

scientific article published on 13 December 2006

Psychostimulants and brain dysfunction: a review of the relevant neurotoxic effects

scientific article

Role of desensitization of AMPA receptors on the neuronal viability and on the [Ca2+]ichanges in cultured rat hippocampal neurons

scientific article published on 01 June 2000

Role of kainate receptor activation and desensitization on the [Ca(2+)](i) changes in cultured rat hippocampal neurons.

scientific article

Role of methamphetamine on glioblastoma cytotoxicity induced by doxorubicin and methotrexate.

scientific article published on 21 March 2014

Solubilization and immunological identification of presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in the rat hippocampus

scientific article

Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes

scientific article published on 19 September 2017

The TNF-α/NF-κB signaling pathway has a key role in methamphetamine-induced blood-brain barrier dysfunction

scientific article published on 22 April 2015

The dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin ameliorates retinal endothelial cell dysfunction triggered by inflammation.

scientific article published on 29 March 2018

The effect of methamphetamine on subventricular zone neurogenesis: Cell death, proliferation and differentiation

The interplay between glioblastoma and microglia cells leads to endothelial cell monolayer dysfunction via the interleukin-6-induced JAK2/STAT3 pathway

scientific article published on 01 April 2019

The putative neuroprotective role of neuropeptide Y in the central nervous system.

scientific article

Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats

scientific article published on April 2005

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