List of works - Jennifer A. Johnston

Aggresomes: a cellular response to misfolded proteins

scientific article

Aging is not associated with proteasome impairment in UPS reporter mice

scientific article

Cytoplasmic dynein/dynactin mediates the assembly of aggresomes

scientific article published in September 2002

Direct interaction of soluble human recombinant tau protein with Abeta 1-42 results in tau aggregation and hyperphosphorylation by tau protein kinase II.

scientific article published on March 2002

Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease

scientific article

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

scientific article published in November 2000

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

scientific article

Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS target

scientific article

Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS

scientific article published in 2012

Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway.

scientific article published in April 1995

Perlecan domain V inhibits α2 integrin-mediated amyloid-β neurotoxicity

scientific article

Phosphoprotein phosphatase 1 (PP1) is a component of the isolated sea urchin mitotic apparatus

scientific article published in January 1994

Rings, chains and ladders: ubiquitin goes to work in the neuron.

scientific article published in July 2004

Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases

scientific article

Systems-based analyses of brain regions functionally impacted in Parkinson's disease reveals underlying causal mechanisms

scientific article

Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease

scientific article

The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition

scientific article

List of works by Jennifer A. Johnston

Aggresomes: a cellular response to misfolded proteins

Aging is not associated with proteasome impairment in UPS reporter mice

Cytoplasmic dynein/dynactin mediates the assembly of aggresomes

Direct interaction of soluble human recombinant tau protein with Abeta 1-42 results in tau aggregation and hyperphosphorylation by tau protein kinase II.

Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS target

Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS

Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway.

Perlecan domain V inhibits α2 integrin-mediated amyloid-β neurotoxicity

Phosphoprotein phosphatase 1 (PP1) is a component of the isolated sea urchin mitotic apparatus

Rings, chains and ladders: ubiquitin goes to work in the neuron.

Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases

Systems-based analyses of brain regions functionally impacted in Parkinson's disease reveals underlying causal mechanisms

Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease

The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition