List of works - Osamu Tetsu

A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation

scientific article

AKT inactivation causes persistent drug tolerance to EGFR inhibitors

scientific article published on 07 October 2015

Cloning and characterization of two transcripts generated from the mel-13 gene positioned adjacent to the mammalian Polycomb group-related gene mel-18.

scientific article published in March 1996

Cyclin D1 harboring the T286I mutation promotes oncogenic activation in endometrial cancer.

scientific article published on 3 June 2013

Drug Resistance to EGFR Inhibitors in Lung Cancer

scientific article published on 25 February 2016

EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function

scientific article published on 6 July 2015

ETS-targeted therapy: can it substitute for MEK inhibitors?

scientific article

ETS1 inactivation causes innate drug resistance to EGFR inhibitors.

scientific article published on 27 August 2015

Establishment and characterization of an oral tongue squamous cell carcinoma cell line from a never-smoking patient

scientific article

Fatty Acid binding protein 7 is a molecular marker in adenoid cystic carcinoma of the salivary glands: implications for clinical significance

scientific article

Genetic profiling reveals cross-contamination and misidentification of 6 adenoid cystic carcinoma cell lines: ACC2, ACC3, ACCM, ACCNS, ACCS and CAC2.

scientific article

Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

scientific article published on 26 January 2006

Germline mutations of MEK in cardio-facio-cutaneous syndrome are sensitive to MEK and RAF inhibition: implications for therapeutic options.

scientific article published on 2 November 2007

Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells.

scientific article published on February 2015

Mammalian Polycomb group genes are categorized as a new type of early response gene induced by B-cell receptor cross-linking

scientific article published on 01 June 1998

Method for screening ecdysone-inducible stable cell lines.

scientific article published in August 2001

Mutations in the c-Kit gene disrupt mitogen-activated protein kinase signaling during tumor development in adenoid cystic carcinoma of the salivary glands

scientific article

Proliferation of cancer cells despite CDK2 inhibition.

scientific article published in March 2003

Resistance to EGFR-targeted therapy by Ets-1 inactivation

scientific article published on 27 August 2015

Successful gene transfer into murine pancreatic islets using polyamine transfection reagents

scientific article published on 01 March 1998

TP53 and CDKN2a mutations in never-smoker oral tongue squamous cell carcinoma.

scientific article published on 20 February 2014

The role of mel-18, a mammalian Polycomb group gene, during IL-7-dependent proliferation of lymphocyte precursors

scientific article published on 01 July 1997

c-Kit Expression is Rate-Limiting for Stem Cell Factor-Mediated Disease Progression in Adenoid Cystic Carcinoma of the Salivary Glands.

scientific article

mel-18 negatively regulates cell cycle progression upon B cell antigen receptor stimulation through a cascade leading to c-myc/cdc25

scientific article published on 01 October 1998

List of works by Osamu Tetsu

A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation

AKT inactivation causes persistent drug tolerance to EGFR inhibitors

Cloning and characterization of two transcripts generated from the mel-13 gene positioned adjacent to the mammalian Polycomb group-related gene mel-18.

Cyclin D1 harboring the T286I mutation promotes oncogenic activation in endometrial cancer.

Drug Resistance to EGFR Inhibitors in Lung Cancer

EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function

ETS-targeted therapy: can it substitute for MEK inhibitors?

ETS1 inactivation causes innate drug resistance to EGFR inhibitors.

Establishment and characterization of an oral tongue squamous cell carcinoma cell line from a never-smoking patient

Fatty Acid binding protein 7 is a molecular marker in adenoid cystic carcinoma of the salivary glands: implications for clinical significance

Genetic profiling reveals cross-contamination and misidentification of 6 adenoid cystic carcinoma cell lines: ACC2, ACC3, ACCM, ACCNS, ACCS and CAC2.

Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

Germline mutations of MEK in cardio-facio-cutaneous syndrome are sensitive to MEK and RAF inhibition: implications for therapeutic options.

Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells.

Mammalian Polycomb group genes are categorized as a new type of early response gene induced by B-cell receptor cross-linking

Method for screening ecdysone-inducible stable cell lines.

Mutations in the c-Kit gene disrupt mitogen-activated protein kinase signaling during tumor development in adenoid cystic carcinoma of the salivary glands

Proliferation of cancer cells despite CDK2 inhibition.

Resistance to EGFR-targeted therapy by Ets-1 inactivation

Successful gene transfer into murine pancreatic islets using polyamine transfection reagents

TP53 and CDKN2a mutations in never-smoker oral tongue squamous cell carcinoma.

The role of mel-18, a mammalian Polycomb group gene, during IL-7-dependent proliferation of lymphocyte precursors

c-Kit Expression is Rate-Limiting for Stem Cell Factor-Mediated Disease Progression in Adenoid Cystic Carcinoma of the Salivary Glands.

mel-18 negatively regulates cell cycle progression upon B cell antigen receptor stimulation through a cascade leading to c-myc/cdc25