List of works - Koleka Mlisana

APOBEC3G expression is dysregulated in primary HIV-1 infection and polymorphic variants influence CD4+ T-cell counts and plasma viral load

scientific article

Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure.

scientific article

An outbreak of multiresistant Salmonella typhi in South Africa

scientific article published on February 1, 1992

Anaemia in acute HIV-1 subtype C infection

scientific article

Antibiotic resistance trends of ESKAPE pathogens in Kwazulu-Natal, South Africa: A five-year retrospective analysis

scientific article published on 06 December 2018

Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point

scientific article published on April 2009

Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection

scientific article

Association of polymorphisms in the LEDGF/p75 gene (PSIP1) with susceptibility to HIV-1 infection and disease progression

scientific article published on September 2011

Beyond syndromic management: Opportunities for diagnosis-based treatment of sexually transmitted infections in low- and middle-income countries.

scientific article published on 24 April 2018

Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region

scientific article published on 19 August 2009

Challenges of diagnosing acute HIV-1 subtype C infection in African women: performance of a clinical algorithm and the need for point-of-care nucleic-acid based testing ⬇️

scientific article

Co-enrollment in multiple HIV prevention trials - experiences from the CAPRISA 004 Tenofovir gel trial

scientific article published on 26 January 2011

Colistin-resistant Acinetobacter baumannii as a cause of neonatal ventriculitis

Comparative Pathogenomics of <i>Aeromonas veronii</i> from Pigs in South Africa: Dominance of the Novel ST657 Clone

scientific article published on 16 December 2020

Conserved positive selection signals in gp41 across multiple subtypes and difference in selection signals detectable in gp41 sequences sampled during acute and chronic HIV-1 subtype C infection

scientific article

Differential impact of magnitude, polyfunctional capacity, and specificity of HIV-specific CD8+ T cell responses on HIV set point

scientific article

Does participation in an HIV vaccine efficacy trial affect risk behaviour in South Africa? ⬇️

scientific article published on January 29, 2013

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women

scientific article

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

scientific article

Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage

scientific article published on 08 April 2022

Enrolling adolescents in research on HIV and other sensitive issues: lessons from South Africa

scientific article published on 18 April 2006

Establishing a cohort at high risk of HIV infection in South Africa: challenges and experiences of the CAPRISA 002 acute infection study

scientific article

Evolution of epidemiologic methods and concepts in selected textbooks of the 20th century

scientific article published on January 2004

Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period

scientific article

First report of neonatal bacteraemia caused by blaNDM-1 Raoultella ornithinolytica

Fluidity of HIV-1-specific T-cell responses during acute and early subtype C HIV-1 infection and associations with early disease progression

scientific article

Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa

scientific article

Genital tract inflammation during early HIV-1 infection predicts higher plasma viral load set point in women

scientific article published on January 2012

Genomic Analysis of Carbapenemase-Producing Extensively Drug-Resistant Klebsiella pneumoniae Isolates Reveals the Horizontal Spread of p18-43_01 Plasmid Encoding blaNDM-1 in South Africa

scientific article published on 17 January 2020

HIV prevention in high-risk women in South Africa: condom use and the need for change

scientific article

HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection

scientific article

Health-related quality of life dynamics of HIV-positive South African women up to ART initiation: evidence from the CAPRISA 002 acute infection cohort study

scientific article

Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection

scientific article published on June 2009

Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point

scientific article published on 22 October 2008

Impact of antiretroviral therapy on health-related quality of life among South African women in the CAPRISA 002 acute infection study

scientific article

In silico Design and Synthesis of Tetrahydropyrimidinones and Tetrahydropyrimidinethiones as Potential Thymidylate Kinase Inhibitors Exerting Anti-TB Activity Against Mycobacterium tuberculosis

scientific article published on 09 March 2020

Increased memory differentiation is associated with decreased polyfunctionality for HIV but not for cytomegalovirus-specific CD8+ T cells

scientific article

Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa

scientific article published on 6 May 2022

Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa

scientific article published on 11 November 2021

Interleukin-10 promoter polymorphisms influence HIV-1 susceptibility and primary HIV-1 pathogenesis

scientific article

Intersubtype differences in the effect of a rare p24 gag mutation on HIV-1 replicative fitness

scientific article

Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection

scientific article

Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin

scientific article

Molecular Characterization of Corynebacterium diphtheriae Outbreak Isolates, South Africa, March-June 2015

scientific article

Molecular modeling studies and anti-TB activity of trisubstituted indolizine analogues; molecular docking and dynamic inputs

scientific article published on 28 June 2017

Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection

scientific article published on 4 April 2007

P09-04. Charge changes in the alpha2-helix in the C3 region of the HIV-1 subtype C envelope mediate neutralization escape

scientific article published on 22 October 2009

P13-05. Factors associated with pregnancy during the HVTN 503/Phambili trial, a phase IIB HIV trial of the Merck Ad-5 multi-clade HIV vaccine

article

P14-02. Social impact events in Phambili, the first phase 2B HIV vaccine trial in South Africa.

scientific article

P14-04. HIV-SELECTEST EIA and rapid test: a novel assay for differential diagnosis of HIV infections in the face of vaccine-generated antibodies.

scientific article published on 22 October 2009

P14-07. Offering new prevention modalities in HIV vaccine trials: experience with male circumcision in the Phambili trial

article

P15-08. Did unblinding affect HIV risk behaviour and risk perception in the HVTN503/Phambili study?

article

P15-13. HVTN 503(Phambili) trial discontinuation of enrolment/vaccination: the impact on trial participant attitudes to vaccine trials and scientific research.

scientific article published on 22 October 2009

Pathogenomic Analysis of a Novel Extensively Drug-Resistant Citrobacter freundii Isolate Carrying a blaNDM-1 Carbapenemase in South Africa

scientific article published on 31 January 2020

Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression

scientific article

Posttraumatic brain abscess caused by Aeromonas hydrophila

scientific article published on 12 March 2014

Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop

scientific article

Pregnancy incidence and correlates during the HVTN 503 Phambili HIV vaccine trial conducted among South African women

scientific article

Quantitating the Multiplicity of Infection with Human Immunodeficiency Virus Type 1 Subtype C Reveals a Non-Poisson Distribution of Transmitted Variants.

scientific article published in July 2009

Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants

scientific article published on 04 February 2009

Rapid disease progression in HIV-1 subtype C-infected South African women

scientific article

Rapid, complex adaptation of transmitted HIV-1 full-length genomes in subtype C-infected individuals with differing disease progression

scientific article published on February 2013

Recombinant adenovirus type 5 HIV gag/pol/nef vaccine in South Africa: unblinded, long-term follow-up of the phase 2b HVTN 503/Phambili study

scientific article

Recruitment of high risk women for HIV prevention trials: baseline HIV prevalence and sexual behavior in the CAPRISA 004 tenofovir gel trial

scientific article

Relationship between Levels of Inflammatory Cytokines in the Genital Tract and CD4+Cell Counts in Women with Acute HIV‐1 Infection

article

Resazurin microtitre plate assay and Sensititre® MycoTB for detection of Mycobacterium tuberculosis resistance in a high tuberculosis resistance setting

scientific article published on 13 December 2019

Rifampicin mono-resistance in Mycobacterium tuberculosis in KwaZulu-Natal, South Africa: a significant phenomenon in a high prevalence TB-HIV region

scientific article (publication date: 2013)

Safety and efficacy of the HVTN 503/Phambili study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study

scientific article

Safety of tenofovir gel, a vaginal microbicide, in South African women: results of the CAPRISA 004 Trial

scientific article published on 23 August 2012

Sequential Immunization with gp140 Boosts Immune Responses Primed by Modified Vaccinia Ankara or DNA in HIV-Uninfected South African Participants

scientific article

Short communication decreased incidence of dual infections in South african subtype C-infected women compared to a cohort ten years earlier

scientific article published on 9 February 2011

Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa

scientific article

Syphilis in the 'unbooked' pregnant woman

scientific article published on 01 July 1992

TRIM5α and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment

scientific article published on 29 January 2014

Temporal association of HLA-B81:01- and HLA-B39:10-mediated HIV-1 p24 sequence evolution with disease progression.

scientific article

The HVTN503/Phambili HIV vaccine trial: a comparison of younger and older participants

scientific article published on 08 October 2013

The c3-v4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection

scientific article

The effect of prior antimicrobial therapy for community acquired infections on the aetiology of early and late onset ventilator-associated pneumonia in a level I trauma intensive care unit

scholarly article published 28 April 2017

The emergence of multi-antibiotic-resistant strains of Salmonella typhi in northern Natal-KwaZulu

scientific article published on March 7, 1992

The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection

scientific article

Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage

scientific article

Utilizing nucleic acid amplification to identify acute HIV infection

scientific article published in March 2007

Virological and immunological factors associated with HIV-1 differential disease progression in HLA-B 58:01-positive individuals

scientific article

Whole-Genome Sequence of a Novel Sequence Type 3136 Carbapenem-Resistant Klebsiella pneumoniae Strain Isolated from a Hospitalized Patient in Durban, South Africa

scientific article published on 13 December 2018

List of works by Koleka Mlisana

APOBEC3G expression is dysregulated in primary HIV-1 infection and polymorphic variants influence CD4+ T-cell counts and plasma viral load

Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure.

An outbreak of multiresistant Salmonella typhi in South Africa

Anaemia in acute HIV-1 subtype C infection

Antibiotic resistance trends of ESKAPE pathogens in Kwazulu-Natal, South Africa: A five-year retrospective analysis

Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point

Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection

Association of polymorphisms in the LEDGF/p75 gene (PSIP1) with susceptibility to HIV-1 infection and disease progression

Beyond syndromic management: Opportunities for diagnosis-based treatment of sexually transmitted infections in low- and middle-income countries.

Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region

Challenges of diagnosing acute HIV-1 subtype C infection in African women: performance of a clinical algorithm and the need for point-of-care nucleic-acid based testing ⬇️

Co-enrollment in multiple HIV prevention trials - experiences from the CAPRISA 004 Tenofovir gel trial

Colistin-resistant Acinetobacter baumannii as a cause of neonatal ventriculitis

Comparative Pathogenomics of <i>Aeromonas veronii</i> from Pigs in South Africa: Dominance of the Novel ST657 Clone

Conserved positive selection signals in gp41 across multiple subtypes and difference in selection signals detectable in gp41 sequences sampled during acute and chronic HIV-1 subtype C infection

Differential impact of magnitude, polyfunctional capacity, and specificity of HIV-specific CD8+ T cell responses on HIV set point

Does participation in an HIV vaccine efficacy trial affect risk behaviour in South Africa? ⬇️

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage

Enrolling adolescents in research on HIV and other sensitive issues: lessons from South Africa

Establishing a cohort at high risk of HIV infection in South Africa: challenges and experiences of the CAPRISA 002 acute infection study

Evolution of epidemiologic methods and concepts in selected textbooks of the 20th century

Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period

First report of neonatal bacteraemia caused by blaNDM-1 Raoultella ornithinolytica

Fluidity of HIV-1-specific T-cell responses during acute and early subtype C HIV-1 infection and associations with early disease progression

Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa

Genital tract inflammation during early HIV-1 infection predicts higher plasma viral load set point in women

Genomic Analysis of Carbapenemase-Producing Extensively Drug-Resistant Klebsiella pneumoniae Isolates Reveals the Horizontal Spread of p18-43_01 Plasmid Encoding blaNDM-1 in South Africa

HIV prevention in high-risk women in South Africa: condom use and the need for change

HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection

Health-related quality of life dynamics of HIV-positive South African women up to ART initiation: evidence from the CAPRISA 002 acute infection cohort study

Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection

Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point

Impact of antiretroviral therapy on health-related quality of life among South African women in the CAPRISA 002 acute infection study

In silico Design and Synthesis of Tetrahydropyrimidinones and Tetrahydropyrimidinethiones as Potential Thymidylate Kinase Inhibitors Exerting Anti-TB Activity Against Mycobacterium tuberculosis

Increased memory differentiation is associated with decreased polyfunctionality for HIV but not for cytomegalovirus-specific CD8+ T cells

Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa

Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa

Interleukin-10 promoter polymorphisms influence HIV-1 susceptibility and primary HIV-1 pathogenesis

Intersubtype differences in the effect of a rare p24 gag mutation on HIV-1 replicative fitness

Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection

Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin

Molecular Characterization of Corynebacterium diphtheriae Outbreak Isolates, South Africa, March-June 2015

Molecular modeling studies and anti-TB activity of trisubstituted indolizine analogues; molecular docking and dynamic inputs

Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection

P09-04. Charge changes in the alpha2-helix in the C3 region of the HIV-1 subtype C envelope mediate neutralization escape

P13-05. Factors associated with pregnancy during the HVTN 503/Phambili trial, a phase IIB HIV trial of the Merck Ad-5 multi-clade HIV vaccine

P14-02. Social impact events in Phambili, the first phase 2B HIV vaccine trial in South Africa.

P14-04. HIV-SELECTEST EIA and rapid test: a novel assay for differential diagnosis of HIV infections in the face of vaccine-generated antibodies.

P14-07. Offering new prevention modalities in HIV vaccine trials: experience with male circumcision in the Phambili trial

P15-08. Did unblinding affect HIV risk behaviour and risk perception in the HVTN503/Phambili study?

P15-13. HVTN 503(Phambili) trial discontinuation of enrolment/vaccination: the impact on trial participant attitudes to vaccine trials and scientific research.

Pathogenomic Analysis of a Novel Extensively Drug-Resistant Citrobacter freundii Isolate Carrying a blaNDM-1 Carbapenemase in South Africa

Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression

Posttraumatic brain abscess caused by Aeromonas hydrophila

Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop

Pregnancy incidence and correlates during the HVTN 503 Phambili HIV vaccine trial conducted among South African women

Quantitating the Multiplicity of Infection with Human Immunodeficiency Virus Type 1 Subtype C Reveals a Non-Poisson Distribution of Transmitted Variants.

Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants

Rapid disease progression in HIV-1 subtype C-infected South African women

Rapid, complex adaptation of transmitted HIV-1 full-length genomes in subtype C-infected individuals with differing disease progression

Recombinant adenovirus type 5 HIV gag/pol/nef vaccine in South Africa: unblinded, long-term follow-up of the phase 2b HVTN 503/Phambili study

Recruitment of high risk women for HIV prevention trials: baseline HIV prevalence and sexual behavior in the CAPRISA 004 tenofovir gel trial

Relationship between Levels of Inflammatory Cytokines in the Genital Tract and CD4+Cell Counts in Women with Acute HIV‐1 Infection

Resazurin microtitre plate assay and Sensititre® MycoTB for detection of Mycobacterium tuberculosis resistance in a high tuberculosis resistance setting

Rifampicin mono-resistance in Mycobacterium tuberculosis in KwaZulu-Natal, South Africa: a significant phenomenon in a high prevalence TB-HIV region

Safety and efficacy of the HVTN 503/Phambili study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study

Safety of tenofovir gel, a vaginal microbicide, in South African women: results of the CAPRISA 004 Trial

Sequential Immunization with gp140 Boosts Immune Responses Primed by Modified Vaccinia Ankara or DNA in HIV-Uninfected South African Participants

Short communication decreased incidence of dual infections in South african subtype C-infected women compared to a cohort ten years earlier

Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa

Syphilis in the 'unbooked' pregnant woman

TRIM5α and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment

Temporal association of HLA-B*81:01- and HLA-B*39:10-mediated HIV-1 p24 sequence evolution with disease progression.

The HVTN503/Phambili HIV vaccine trial: a comparison of younger and older participants

The c3-v4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection

The effect of prior antimicrobial therapy for community acquired infections on the aetiology of early and late onset ventilator-associated pneumonia in a level I trauma intensive care unit

The emergence of multi-antibiotic-resistant strains of Salmonella typhi in northern Natal-KwaZulu

Temporal association of HLA-B81:01- and HLA-B39:10-mediated HIV-1 p24 sequence evolution with disease progression.