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List of works by Takashi Yamamoto

A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector

scientific article published on 17 March 2015

A simple and practical workflow for genotyping of CRISPR-Cas9-based knockout phenotypes using multiplexed amplicon sequencing

scientific article published on 23 April 2020

A triplex DNA structure of the polypyrimidine: polypurine stretch in the 5' flanking region of the sea urchin arylsulfatase gene

scientific article published on 01 February 1996

ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair

scientific article published on 17 November 2017

Abnormal spermatogenesis at low temperatures in the Japanese red-bellied newt, Cynops pyrrhogaster: possible biological significance of the cessation of spermatocytogenesis

scientific article published in September 2003

Analysis of cis-regulatory elements controlling spatio-temporal expression of T-brain gene in sea urchin, Hemicentrotus pulcherrimus

scientific article published on 25 October 2007

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection

scientific article published on 16 November 2016

Cancer induction and suppression with transcriptional control and epigenome editing technologies

scientific article published on 14 November 2017

Cas9, Cpf1 and C2c1/2/3-What's next?

scientific article published on 31 January 2017

Cilia play a role in breaking left-right symmetry of the sea urchin embryo.

scientific article published on 29 March 2016

Cloning of dynein intermediate chain cDNA of the newt Cynops pyrrhogaster

scientific article published on 01 April 2001

Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice.

scientific article published on 29 April 2015

Clustered Xenopus keratin genes: A genomic, transcriptomic, and proteomic analysis

scientific article published on 11 November 2016

Cold suppression of follicle-stimulating hormone activity on proliferation and survival of newt spermatogonia.

scientific article

Culture time of vitrified/warmed zygotes before microinjection affects the production efficiency of CRISPR-Cas9-mediated knock-in mice.

scientific article

DNA variations within the sea urchin Otx gene enhancer

scientific article published on 16 October 2007

Depdc5 knockout rat: A novel model of mTORopathy

scientific article published on 9 February 2016

Desmocollin-2 alone forms functional desmosomal plaques, with the plaque formation requiring the juxtamembrane region and plakophilins

scientific article published on 13 May 2015

Detailed analysis of targeted gene mutations caused by the Platinum-Fungal TALENs in Aspergillus oryzae RIB40 strain and a ligD disruptant.

scientific article published on 22 October 2016

Developmental expression of HpNanos, the Hemicentrotus pulcherrimus homologue of nanos

scientific article

Dicer is required for the normal development of sea urchin, Hemicentrotus pulcherrimus.

scientific article published in June 2010

Differential expression of annexin V during spermatogenesis in the newt Cynops pyrrhogaster.

scientific article

Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies

scientific article published on 27 August 2014

EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step

scientific article

Efficient TALEN construction and evaluation methods for human cell and animal applications.

scientific article published on 6 February 2013

Efficient Targeted Mutagenesis in Medaka Using Custom-Designed Transcription Activator-Like Effector Nucleases ⬇️

scientific article published on January 3, 2013

Efficient and multiplexable genome editing using Platinum TALENs in oleaginous microalga, Nannochloropsis oceanica NIES-2145

scientific article published on 05 September 2020

Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotes ⬇️

scientific article published on February 13, 2013

Efficient modification of the myostatin gene in porcine somatic cells and generation of knockout piglets.

scientific article published on 21 October 2015

Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc-finger nucleases

scientific article published on 28 May 2012

Enhancer activity sensitive to the orientation of the gene it regulates in the chordategenome ⬇️

scientific article published on December 27, 2012

Equarin is involved as an FGF signaling modulator in chick lens differentiation

scientific article published on 31 May 2012

Establishment of Functional Genomics Pipeline in Epiblast-Like Tissue by Combining Transcriptomic Analysis and Gene Knockdown/Knockin/Knockout, Using RNA Interference and CRISPR/Cas9.

scientific article

Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.

scientific article published on 16 March 2016

Establishment of expanded and streamlined pipeline of PITCh knock-in - a web-based design tool for MMEJ-mediated gene knock-in, PITCh designer, and the variations of PITCh, PITCh-TG and PITCh-KIKO.

scientific article

Establishment of pten knockout medaka with transcription activator-like effector nucleases (TALENs) as a model of PTEN deficiency disease

scientific article published on 20 October 2017

Evaluation of ATM heterozygous mutations underlying individual differences in radiosensitivity using genome editing in human cultured cells.

scientific article

Exploration of genetic basis underlying individual differences in radiosensitivity within human populations using genome editing technology.

scientific article published in April 2018

Expression of a novel matrix metalloproteinase gene during Cynops early embryogenesis

scientific article published on 01 October 2001

Expression of activin beta subunit genes in Sertoli cells of newt testes

scientific article published in July 1996

FAST-id system for enrichment of cells with TALEN-induced mutations and large deletions

scientific article

Follicle-stimulating hormone is indispensable for the last spermatogonial mitosis preceding meiosis initiation in newts (Cynops pyrrhogaster)

scientific article published on 01 January 2002

Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway

scientific article

Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation

scientific article (publication date: 2016)

Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa

scientific article published on 20 June 2016

Gene cassette knock-in in mammalian cells and zygotes by enhanced MMEJ

scientific article

Generation of D1-1 TALEN isogenic control cell line from Dravet syndrome patient iPSCs using TALEN-mediated editing of the SCN1A gene

scientific article published on 2 February 2018

Generation of mutant mice via the CRISPR/Cas9 system using FokI-dCas9

scientific article published on 9 June 2015

Genome Editing in Mouse Spermatogonial Stem Cell Lines Using TALEN and Double-Nicking CRISPR/Cas9.

scientific article

Genome editing for dissecting and curing human genetic diseases

scientific article published on 25 January 2018

Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells

scientific article published on 17 June 2020

Germ cell mutations of the ascidian Ciona intestinalis with TALE nucleases.

scientific article published on 19 March 2014

Germ cell regeneration-mediated, enhanced mutagenesis in the ascidian Ciona intestinalis reveals flexible germ cell formation from different somatic cells.

scientific article published in February 2017

High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos

scientific article published on 4 March 2013

Highly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system.

scientific article

Highly efficient targeted mutagenesis in one-cell mouse embryos mediated by the TALEN and CRISPR/Cas systems

scientific article

Highly multiplexed CRISPR-Cas9-nuclease and Cas9-nickase vectors for inactivation of hepatitis B virus

scientific article published on 23 September 2016

Homeolog-specific targeted mutagenesis in Xenopus laevis using TALENs

scientific article published on 29 April 2015

Homologous Recombination-Independent Large Gene Cassette Knock-in in CHO Cells Using TALEN and MMEJ-Directed Donor Plasmids.

scientific article

Hox-mediated endodermal identity patterns pharyngeal muscle formation in the chordate pharynx.

scientific article published on 13 March 2017

Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation

scientific article published on 19 November 2015

Human recombinant stem cell factor promotes spermatogonial proliferation, but not meiosis initiation in organ culture of newt testis fragments

scientific article published on 01 June 2002

Identification of two teleost homologs of the Drosophila sex determination factor, transformer-2 in medaka (Oryzias latipes).

scientific article published in July 2004

In vivo tracking of histone H3 lysine 9 acetylation in Xenopus laevis during tail regeneration

scientific article published on 24 February 2016

Low temperature promotes annexin V expression in newt testis

scientific article published in June 2003

MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems.

scientific article published on 17 December 2015

Magic wands of CRISPR-lots of choices for gene knock-in.

scientific article

Mammalian follicle-stimulating hormone and insulin-like growth factor I (IGF-I) up-regulate IGF-I gene expression in organ culture of newt testis

scientific article published on 01 September 2001

Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9

scientific article

Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology

scientific article published on 9 November 2017

Molecular cloning, functional characterization, and gene expression of a follicle-stimulating hormone receptor in the testis of newt Cynops pyrrhogaster

scientific article published in August 2000

Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system

scientific article published on 23 June 2014

Non-RVD mutations that enhance the dynamics of the TAL repeat array along the superhelical axis improve TALEN genome editing efficacy

scientific article published on 24 November 2016

Nucleosome exclusion from the interspecies-conserved central AT-rich region of the Ars insulator

scientific article published on 19 September 2011

Organ-specific and age-dependent expression of insulin-like growth factor-I (IGF-I) mRNA variants: IGF-IA and IB mRNAs in the mouse

scientific article

PAX2 is dispensable for in vitro nephron formation from human induced pluripotent stem cells.

scientific article published on 3 July 2017

PLK1-mediated phosphorylation of WDR62/MCPH2 ensures proper mitotic spindle orientation

scientific article published on 26 August 2017

Partial exogastrulation due to apical–basal polarity of F‐actin distribution disruption in sea urchin embryo by omeprazole

scientific article published in 2022

Participation of androgen and its receptor in sex determination of an amphibian species.

scientific article

Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9.

scientific article published on 26 November 2014

Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish

scientific article

Production of Sry knockout mouse using TALEN via oocyte injection.

scientific article

Production of knockout mice by DNA microinjection of various CRISPR/Cas9 vectors into freeze-thawed fertilized oocytes

scientific article published on 22 May 2015

Prolactin induces apoptosis in the penultimate spermatogonial stage of the testes in Japanese red-bellied newt (Cynops pyrrhogaster)

scientific article published on 01 June 2000

Promotion of cathepsin L activity in newt spermatogonial apoptosis induced by prolactin.

scientific article

Quadruple zebrafish mutant reveals different roles of Mesp genes in somite segmentation between mouse and zebrafish.

scientific article published on 6 July 2016

Quantitative assay for TALEN activity at endogenous genomic loci

scientific article

RSF governs silent chromatin formation via histone H2Av replacement

scientific article

Rapid and efficient analysis of gene function using CRISPR-Cas9 in Xenopus tropicalis founders

scientific article published on 24 May 2016

Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines

scientific article

Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity.

scientific article

Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara.

scientific article published on 29 March 2016

Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells

scientific article published on 16 July 2015

Sexually dimorphic expression of a teleost homologue of Müllerian inhibiting substance during gonadal sex differentiation in Japanese flounder, Paralichthys olivaceus

scientific article published on 01 September 2004

Simple knockout by electroporation of engineered endonucleases into intact rat embryos

scientific article

Simultaneous live imaging of the transcription and nuclear position of specific genes.

scientific article

Single-Cell-State Culture of Human Pluripotent Stem Cells Increases Transfection Efficiency.

scientific article published on May 2016

Smarcal1 promotes double-strand-break repair by nonhomologous end-joining.

scientific article published on 18 June 2015

Sterol side chain reductase 2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal glycoalkaloids in potato

scientific article published on 12 September 2014

Suppressor of Hairless (Su(H)) is required for foregut development in the sea urchin embryo.

scientific article published in October 2009

TALEN-induced gene knock out in Drosophila

scientific article

TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome.

scientific article published on 16 December 2013

Tailor-made TALEN system for highly efficient targeted gene replacement in the rice blast fungus

article

Targeted disruption of exogenous EGFP gene in medaka using zinc-finger nucleases.

scientific article published on 30 May 2012

Targeted gene correction of RUNX1 in induced pluripotent stem cells derived from familial platelet disorder with propensity to myeloid malignancy restores normal megakaryopoiesis

scientific article

Targeted gene disruption by use of transcription activator-like effector nuclease (TALEN) in the water flea Daphnia pulex

scientific article

Targeted genome editing

scientific article published in January 2014

Targeted mutagenesis in sea urchin embryos using TALENs.

scientific article published on 21 November 2013

Targeted mutagenesis of multiple and paralogous genes in Xenopus laevis using two pairs of transcription activator-like effector nucleases.

scientific article published on 11 December 2013

Temporal effects of Notch signaling and potential cooperation with multiple downstream effectors on adenohypophysis cell specification in zebrafish

scientific article published on 29 March 2016

The 3'UTR of nanos2 directs enrichment in the germ cell lineage of the sea urchin

scientific article published on 25 January 2013

The Ars insulator facilitates I-SceI meganuclease-mediated transgenesis in the sea urchin embryo.

scientific article published in September 2008

The Expression of TALEN before Fertilization Provides a Rapid Knock-Out Phenotype in Xenopus laevis Founder Embryos

scientific article published on 18 November 2015

The Microtubule-Depolymerizing Activity of a Mitotic Kinesin Protein KIF2A Drives Primary Cilia Disassembly Coupled with Cell Proliferation.

scientific article published on 04 February 2015

Tissue-specific and ubiquitous gene knockouts by TALEN electroporation provide new approaches to investigating gene function in Ciona.

scientific article published on 18 December 2013

Transcription activator-like effector nucleases efficiently disrupt the target gene in Iberian ribbed newts (Pleurodeles waltl), an experimental model animal for regeneration.

scientific article published on 11 December 2013

Transcriptional regulation of a horizontally transferred gene from bacterium to chordate.

scientific article published in December 2016

Ultra-superovulation for the CRISPR-Cas9-mediated production of gene-knockout, single-amino-acid-substituted, and floxed mice.

scientific article published on 07 July 2016

Unexpected heterogeneity derived from Cas9 ribonucleoprotein-introduced clonal cells at the HPRT1 locus

scientific article published on 9 February 2018

Unliganded thyroid hormone receptor α regulates developmental timing via gene repression in Xenopus tropicalis

scientific article

Versatile strategy for isolating transcription activator-like effector nuclease-mediated knockout mutants in Caenorhabditis elegans

scientific article published on 17 December 2013

Zinc-finger nuclease-mediated targeted insertion of reporter genes for quantitative imaging of gene expression in sea urchin embryos.

scientific article

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