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List of works by François Marceau

A fluorescent version of the bradykinin B2 receptor antagonist B-9430: pharmacological characterization and use in live cell imaging

scientific article published on 17 May 2008

A ligand-based approach to investigate the expression and function of angiotensin converting enzyme in intact human umbilical vein endothelial cells

scientific article published on 7 May 2010

A non-peptide antagonist unusually selective for the human form of the bradykinin B2 receptor

scientific article published in October 2003

A nonpeptide antagonist reveals a highly glycosylated state of the rabbit kinin B1 receptor.

scientific article published on 11 January 2006

A novel nonpeptide antagonist of the kinin B1 receptor: effects at the rabbit receptor

scientific article published on 26 July 2004

A possible common pharmacophore in the non-peptide antagonists of the bradykinin B1 receptor

scientific article published on 01 March 2005

A tagged parathyroid hormone derivative as a carrier of antibody cargoes transported by the G protein coupled PTH1 receptor.

scientific article

Absence of ligand-induced regulation of kinin receptor expression in the rabbit

scientific article

Abstracts from the 10th C1-inhibitor deficiency workshop.

scientific article

Advances in the development of bradykinin receptor ligands

scientific article published on January 2006

Agonist-induced translocation of the kinin B(1) receptor to caveolae-related rafts.

scientific article published in March 2002

Altered cardiac bradykinin metabolism in experimental diabetes caused by the variations of angiotensin-converting enzyme and other peptidases.

scientific article published in April 2010

Altered frequency of a promoter polymorphic allele of the kinin B1 receptor gene in inflammatory bowel disease

scientific article

Altered frequency of a promoter polymorphism of the kinin B2 receptor gene in hypertensive African-Americans.

scientific article published in December 2000

Aminopeptidase modulation of the pharmacological responses to synthetic thrombin receptor agonists

scientific article published on 01 March 1994

An in vitro reconstitution system to address the mechanism of the vascular expression of the bradykinin B₁ receptor in response to angiotensin converting enzyme inhibition

scientific article published on 02 October 2011

Anaphylatoxin C5a fails to promote prostacyclin release in cultured endothelial cells from human umbilical veins

scientific article published on 01 October 1986

Angiotensin converting enzyme inhibitor induced angio-oedema: a review of the pathophysiology and risk factors.

scientific article published on 29 July 2009

Antagonist, partial agonist and antiproliferative actions of B-9870 (CU201) as a function of the expression and density of the bradykinin B1 and B2 receptors

scientific article

Assessment of cation trapping by cellular acidic compartments.

scientific article

Autophagic flux inhibition and lysosomogenesis ensuing cellular capture and retention of the cationic drug quinacrine in murine models

scientific article published on 6 October 2015

B-9972 (D-Arg-[Hyp3,Igl5,Oic7,Igl8]-bradykinin) is an inactivation-resistant agonist of the bradykinin B2 receptor derived from the peptide antagonist B-9430 (D-Arg-[Hyp3,Igl5,D-Igl7,Oic8]-bradykinin): pharmacologic profile and effective induction o

scientific article published on 15 August 2007

Bacitracin U.S.P. contains a factor that stimulates receptors for 5-hydroxytryptamine on rabbit aortic strips

scientific article published on 01 January 1990

Bifunctional epitope-agonist ligands of the bradykinin B(2) receptor

scientific article published in March 2013

Bifunctional fusion proteins containing the sequence of the bradykinin homologue maximakinin: activities at the rat bradykinin B₂ receptor

scientific article published on 7 February 2018

Bifunctional ligands of the bradykinin B2 and B1 receptors: An exercise in peptide hormone plasticity

scientific article published on 23 May 2018

Biotechnological Fluorescent Ligands of the Bradykinin B1 Receptor: Protein Ligands for a Peptide Receptor

scientific article

Bradykinin B2 receptor gene polymorphism is associated with altered urinary albumin/creatinine values in diabetic patients.

scientific article published in April 2002

Bradykinin B₂ receptor-mediated transport into intact cells: anti-receptor antibody-based cargoes

scientific article published on 07 July 2011

Bradykinin forming capacity of oversulfated chondroitin sulfate contaminated heparin in vitro

scientific article

Bradykinin receptor ligands: therapeutic perspectives

scientific article published in October 2004

Bradykinin receptors: Agonists, antagonists, expression, signaling, and adaptation to sustained stimulation

scientific article published on 24 February 2020

C-C chemokine receptor-7 mediated endocytosis of antibody cargoes into intact cells

scientific article published on 24 September 2013

Carboxypeptidase N (kininase I) activity in blood and synovial fluid from patients with arthritis

scientific article published on 01 September 1987

Cardiovascular expression of inflammatory signaling molecules, the kinin B1 receptor and COX2, in the rabbit: effects of LPS, anti-inflammatory and anti-hypertensive drugs

scientific article published on 14 September 2007

Cation trapping by cellular acidic compartments: beyond the concept of lysosomotropic drugs

scientific article published on 13 December 2011

Characterization of a fluorescent conjugate of the rabbit angiotensin AT(1) receptor.

scientific article published on April 2003

Characterization of a polymorphism in the coding region of the human C5a anaphylatoxin receptor

scientific article published on 01 July 1999

Cloning and preliminary pharmacological characterization of the anaphylatoxin C5a receptor in the rabbit.

scientific article published on September 1999

Comparing Pathways of Bradykinin Formation in Whole Blood From Healthy Volunteers and Patients With Hereditary Angioedema Due to C1 Inhibitor Deficiency

Comparison of two classes of non-peptide drugs as antagonists of neutrophil receptors for f-Met-Leu-Phe. Pyrazolons and iodinated radiographic contrast agents

scientific article published on February 4, 1992

Contractile effect of anaphylatoxin C5a and of a mimetic peptide on the human umbilical artery: further evidence for leukocyte-dependent vasomotion

scientific article

D-Arg0-Bradykinin-Arg-Arg, a Latent Vasoactive Bradykinin B2 Receptor Agonist Metabolically Activated by Carboxypeptidases

scientific article published on 27 March 2018

Design of fluorescent bradykinin analogs: application to imaging of B2 receptor-mediated agonist endocytosis and trafficking and angiotensin-converting enzyme

scientific article published on 04 January 2011

Development of a binding assay for the B1 receptors for kinins

scientific article published on 01 March 1995

Discovery of a dual-function peptide that combines aminopeptidase N inhibition and kinin B1 receptor antagonism

scientific article published on 20 December 2005

Dissociation of the vacuolar and macroautophagic cytopathology from the cytotoxicity induced by the lipophilic local anesthetic bupivacaine

scientific article published in July 2011

Do angiotensin-converting enzyme inhibitors directly stimulate the kinin B1 receptor?

scientific article published on 20 March 2003

Does zaltoprofen antagonize the bradykinin receptors?

scientific article published on 26 January 2007

Down-regulation of interleukin-1beta production and PGE2 accumulation by an indomethacin-phenylalanine derivative in human monocytes

scientific article published in January 1998

Dual antagonists of the bradykinin B1 and B2 receptors based on a postulated common pharmacophore from existing non-peptide antagonists

scientific article published in February 2006

Editorial: Correspondence from Chirumbolo and Bjorklund.

scientific article published on 5 January 2018

Editorial: Improving the data reproducibility and general interest of natural product submissions

scientific article

Effect of interferon-γ on inflammatory cytokine-induced bradykinin B1 receptor expression in human vascular cells.

scientific article

Effects of experimental conditions on the production of interleukin-1 alpha and -1 beta by human endothelial cells cultured in vitro

scientific article published on May 1, 1992

Effects of inactivation-resistant agonists on the signalling, desensitization and down-regulation of bradykinin B(2) receptors.

scientific article published on 28 September 2009

Effects of low molecular weight fibrin degradation products 6A and 6D on rabbit aorta strips

scientific article published in October 1987

Endogenous aminopeptidase N decreases the potency of peptide agonists and antagonists of the kinin B1 receptors in the rabbit aorta

scientific article published on 26 May 2005

Epidermal growth factor-induced rapid relaxation of the isolated rabbit mesenteric artery

scientific article published on 01 June 1994

Evidence for vascular tone regulation by resident or infiltrating leukocytes.

scientific article published on November 1996

Expression of kinin B(1) receptor in fresh or cultured rabbit aortic smooth muscle: role of NF-kappa B.

scientific article

Expression of metallopeptidases and kinin receptors in swine oropharyngeal tissues: effects of angiotensin I-converting enzyme inhibition and inflammation.

scientific article

Fluorescent ligands of the bradykinin B1 receptors: pharmacologic characterization and application to the study of agonist-induced receptor translocation and cell surface receptor expression.

scientific article

Further analysis of the upregulation of bradykinin B1 receptors in isolated rabbit aorta by using metabolic inhibitors

scientific article published on 01 December 1994

Generation of kinins during preparation and storage of whole blood-derived platelet concentrates

scientific article published in March 2007

Green fluorescent protein fused to peptide agonists of two dissimilar G protein-coupled receptors: novel ligands of the bradykinin B2 (rhodopsin family) receptor and parathyroid hormone PTH1 (secretin family) receptor

scientific article

Guest editorial for the special issue peptide receptors: focus on neuropeptides and kinins

scientific article published on 20 October 2009

High affinity capture and concentration of quinacrine in polymorphonuclear neutrophils via vacuolar ATPase-mediated ion trapping: comparison with other peripheral blood leukocytes and implications for the distribution of cationic drugs

scientific article published on 17 April 2013

High agonist-independent clearance of rabbit kinin B1 receptors in cultured cells.

scientific article

Human kallikrein hK2 has low kininogenase activity while prostate-specific antigen (hK3) has none

scientific article published on 01 November 1997

In Vitro Modeling of Bradykinin-Mediated Angioedema States

scientific article published on 19 August 2020

In Vitro Pharmacological Profile of a New Small Molecule Bradykinin B2 Receptor Antagonist

scientific article published on 19 June 2020

In Vivo Effects of Bradykinin B2 Receptor Agonists with Varying Susceptibility to Peptidases.

scientific article published in January 2015

Increased fibrinolysis-induced bradykinin formation in hereditary angioedema confirmed using stored plasma and biotechnological inhibitors

scientific article published on 27 May 2019

Induction of beta 1-receptors for kinins in the rabbit by a bacterial lipopolysaccharide

scientific article published in April 1981

Inflammatory hyperalgesia induced by zymosan in the plantar tissue of the rat: effect of kinin receptor antagonists

scientific article published on 01 February 2000

Infrared-emitting, peptidase-resistant fluorescent ligands of the bradykinin B2 receptor: application to cytofluorometry and imaging

scientific article

Inhibition of human and rabbit arterial smooth muscle cell migration mediated by the kinin B1 receptor: role of receptor density and released mediators

scientific article published on 01 November 2006

Inhibitory effects of cytoskeleton disrupting drugs and GDP-locked Rab mutants on bradykinin B₂ receptor cycling

scientific article published on 27 February 2013

Intense pseudotransport of a cationic drug mediated by vacuolar ATPase: procainamide-induced autophagic cell vacuolization

scientific article

International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences

scientific article (publication date: March 2005)

Intracellular sequestration of amiodarone: role of vacuolar ATPase and macroautophagic transition of the resulting vacuolar cytopathology.

scientific article published on 7 July 2009

Introduction: Natural product-based drug discovery in Immunopharmacology.

scientific article

Kinin B1 receptors: a review.

scientific article

Kinin receptors

scientific article published on 01 January 1998

Kinin receptors: functional aspects.

scientific article

Kininases and vascular responses to kinins

scientific article published on 01 February 1982

Lack of direct interaction between enalaprilat and the kinin B1 receptors

scientific article

Ligand-mediated regulation of kinin receptors in the rabbit.

scientific article published in January 2001

Long-term culture and characterization of human limbal microvascular endothelial cells.

scientific article

Loss of function of vascular smooth muscle cells by nitric oxide-dependent and -independent interactions with tumorigenic cells

scientific article published on December 2004

Lysosomotropic cationic drugs induce cytostatic and cytotoxic effects: Role of liposolubility and autophagic flux and antagonism by cholesterol ablation.

scientific article published on 8 June 2016

Massive cell vacuolization induced by organic amines such as procainamide.

scientific article published on 8 March 2004

Measurement of Bradykinin Formation and Degradation in Blood Plasma: Relevance for Acquired Angioedema Associated With Angiotensin Converting Enzyme Inhibition and for Hereditary Angioedema Due to Factor XII or Plasminogen Gene Variants

scientific article published on 17 July 2020

Mechanism of the contractile effect of diaspirin-cross-linked hemoglobin in rat isolated aorta strip denuded of endothelium as revealed using an oil-immersion procedure

scientific article published on 01 October 1996

Met-Lys-bradykinin-Ser-Ser, a peptide produced by the neutrophil from kininogen, is metabolically activated by angiotensin converting enzyme in vascular tissue

scientific article published on 11 August 2011

Mitogenic effect of bradykinin and of des-Arg9-bradykinin on cultured fibroblasts.

scientific article

Molecular identification and pharmacological profile of the bovine kinin B1 receptor

scientific article

N-substituted 4-aminobenzamides (procainamide analogs): an assessment of multiple cellular effects concerning ion trapping

scientific article published on 23 September 2005

N-terminal extended conjugates of the agonists and antagonists of both bradykinin receptor subtypes: structure-activity relationship, cell imaging using ligands conjugated with fluorophores and prospect for functionally active cargoes.

scientific article published on 18 February 2012

NLRP3 promotes autophagy of urate crystals phagocytized by human osteoblasts.

scientific article

NTPDase1 (CD39) controls nucleotide-dependent vasoconstriction in mouse.

scientific article published on January 2010

Non-competitive pharmacological antagonism at the rabbit B(1) receptor.

scientific article published on November 2000

Pharmacological effects of recombinant human tissue kallikrein on bradykinin B2 receptors

scientific article published on 10 February 2015

Pharmacological evidence of bradykinin regeneration from extended sequences that behave as peptidase-activated B2 receptor agonists.

scientific article published on 7 March 2014

Pharmacological modulation of interleukin 1 production by cultured endothelial cells from human umbilical veins ⬇️

scientific article published on March 1, 1990

Pharmacological modulation of the up-regulated responses to des-Arg9-bradykinin in vivo and in vitro

scientific article published on 01 May 1989

Pharmacological profile of a bifunctional ligand of the formyl peptide receptor1 fused to the myc epitope.

scientific article

Pharmacology of kinins: Their relevance to tissue injury and inflammation ⬇️

scientific article published on January 1, 1983

Production and evaluation of parathyroid hormone receptor1 ligands with intrinsic or assembled peroxidase domains

scientific article published on 12 October 2017

Prolonged signalling and trafficking of the bradykinin B2 receptor stimulated with the amphibian peptide maximakinin: insight into the endosomal inactivation of kinins

scientific article published on 16 November 2011

Quantification of des-Arg9-bradykinin using a chemiluminescence enzyme immunoassay: application to its kinetic profile during plasma activation

scientific article published on 01 March 1995

Rapid assay of human plasma carboxypeptidase N by high-performance liquid chromatographic separation of hippuryl-lysine and its product

scientific article published on 01 August 1983

Receptor tyrosine kinases as mediators of injury-induced bradykinin B1 receptor expression in rabbit aortic smooth muscle.

scientific article published on 21 January 2009

Receptor-independent, vacuolar ATPase-mediated cellular uptake of histamine receptor-1 ligands: possible origin of pharmacological distortions and side effects

scientific article published on 7 February 2008

Recombinant Human Hemoglobin (rHb1.1) Selectively Inhibits Vasorelaxation Elicited by Nitric Oxide Donors in Rabbit Isolated Aortic Rings ⬇️

scientific article published on 01 April 1995

Reprint of: Editorial: Correspondence from Chirumbolo and Bjorklund

scientific article published on 07 July 2018

Role of nuclear factor-kappaB and protein kinase C signaling in the expression of the kinin B1 receptor in human vascular smooth muscle cells

scientific article

S100A9 potentiates the activation of neutrophils by the etiological agent of gout, monosodium urate crystals.

scientific article published on 26 May 2017

Selective induction of cardiovascular responses to des-Arg9-bradykinin by bacterial endotoxin

scientific article published in January 1984

Species-specific pharmacology of maximakinin, an amphibian homologue of bradykinin: putative prodrug activity at the human B2 receptor and peptidase resistance in rats

scientific article published on 18 January 2017

Structural modification of the highly potent peptide bradykinin B1 receptor antagonist B9958.

scientific article published on 5 July 2007

Studies on rabbit natural and recombinant tissue factors: intracellular retention and regulation of surface expression in cultured cells

scientific article published on 14 January 2005

Synthetic C5a receptor agonists. Pharmacology, metabolism and in vivo cardiovascular and hematologic effects.

scientific article

The Development of a Targeted and More Potent, Anti-Inflammatory Derivative of Colchicine: Implications for Gout

scientific article published on 26 June 2020

The ability of des-Arg9-bradykinin to relax rabbit isolated mesenteric arteries is acquired during in vitro incubation

scientific article published on 01 October 1987

The antiwrinkle effect of topical concentrated 2-dimethylaminoethanol involves a vacuolar cytopathology

scientific article published on 01 March 2007

The bradykinin B2 receptor antagonist icatibant (Hoe 140) blocks aminopeptidase N at micromolar concentrations: off-target alterations of signaling mediated by the bradykinin B1 and angiotensin receptors

scientific article published on 08 September 2006

The isolated human umbilical vein as a bioassay for kinin-generating proteases: An in vitro model for therapeutic angioedema agents

scientific article published on 07 May 2016

The kallikrein-kinin system: current and future pharmacological targets.

scientific article

The kallikrein-kininogen-kinin system: lessons from the quantification of endogenous kinins.

scientific article

The kinin B<SUB>1 </SUB>receptor: an inducible G protein coupled receptor

scientific article published on June 1, 1997

Tissue kallikrein actions at the rabbit natural or recombinant kinin B2 receptors.

scientific article published on 3 February 2003

Trapping of adrenergic decongestant drugs into cellular endomembrane compartments: toxicological and pharmacological consequences

scientific article published on 27 July 2007

Tumor cells expressing tissue factor influence the migration of smooth muscle cells in a catalytic activity-dependent way.

scientific article published on September 2009

Vacuolar ATPase-mediated cellular concentration and retention of quinacrine: a model for the distribution of lipophilic cationic drugs to autophagic vacuoles

scientific article published on 22 September 2009

Vacuolar ATPase-mediated sequestration of local anesthetics in swollen macroautophagosomes.

scientific article published on 7 January 2010

Vascular smooth muscle contractility assays for inflammatory and immunological mediators

scientific article published on 08 September 2010

Vasopeptidase-activated latent ligands of the histamine receptor-1.

scientific article published on 7 September 2013

Wortmannin alters the intracellular trafficking of the bradykinin B2 receptor: role of phosphoinositide 3-kinase and Rab5.

scientific article published on October 2003

[Anti-wrinkle properties of amines: vacuolar cytopathology mediated by the V-ATPase]

scientific article published on 01 June 2007

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